Beneficial effects of SARS-CoV-2 vaccination resulting from the COVID-19 pandemic with regard to the uptake of influenza virus, pneumococcal, and herpes zoster adult vaccination - a narrative literature review
Ann Agric Environ Med. 2023 Dec 22;30(4):587-594. doi: 10.26444/aaem/176747. Epub 2023 Dec 20.ABSTRACTINTRODUCTION AND OBJECTIVE: Analysis of factors influencing COVID-19 vaccination coverage in various countries raised the question whether the recent pandemic affected the vaccination rates of other pathogens in adults. Therefore, the aim of this review article was to analyse the literature to find potentially beneficial effects of the introduction of the large-scale vaccinations resulting from the COVID-19 pandemic, with regard to the influenza virus, pneumococcal and herpes zoster adult vaccinations, in order to identify...
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Karolina K łoda Artur Mierzecki Agnieszka Mastalerz-Migas Mateusz Babicki Source Type: research

Pneumococcal population dynamics: Investigating vaccine-induced changes through multiscale modelling
by Nicola Mulberry, Alexander R. Rutherford, Caroline Colijn The mechanisms behind vaccine-induced strain replacement in the pneumococcus remain poorly understood. There is emerging evidence that distinct pneumococcal lineages can co-colonise for significant time periods, and that novel recombinants can readily emerge during natural colonisation. Despite this, patterns of post-vaccine replacement are indicative of competition between specific lineages. Here, we develop a multiscale transmission model to investigate explicitly how within host dynamics shape observed ecological patterns, both pre- and post-vaccination. Our ...
Source: PLoS Computational Biology - December 28, 2023 Category: Biology Authors: Nicola Mulberry Source Type: research

Nasopharyngeal carriage and antibiotic susceptibility patterns of Sstreptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus among urban Ugandan children post-PCV10 introduction: a cross-sectional study
In 2013, Uganda introduced the PCV10 pneumococcal vaccine and it is given to children at 6, 10 and 14 weeks after birth. Carriage prevalence studies post PCV10-introduction are necessary for monitoring the impact of vaccination and trends in antibiotic resistance. Here, we studied carriage/antibiotic resistance of Streptococcus pneumoniae (pneumococcus),Haemophilus influenzae, Moraxella catarrhalis, andStaphylococcus aureus isolated from 194 children at the Mulago Assessment Centre clinic in Kampala-Uganda, 5 years post-PCV10 introduction. Almost all the children were vaccinated with PCV10 (98.5%, 191/194). The overall car...
Source: African Health Sciences - December 27, 2023 Category: African Health Authors: Nshimiyimana Thadd ée , Najjuka Christine Florence , Nalwanga Winnie , Katende George , Kateete David Patrick Source Type: research

Design, development, and assessment of a novel multi-peptide vaccine targeting PspC, PsaA, and PhtD proteins of Streptococcus pneumoniae
This report for the first time presents a novel multi-peptide vaccine composed of immunodominant peptides of PspC, PsaA, and PhtD. In general, the experimental results supported the immunoinformatics predictions.PMID:38143051 | DOI:10.1016/j.ijbiomac.2023.128924 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - December 24, 2023 Category: Biochemistry Authors: Zohreh Bahadori Mona Shafaghi Jahangir Sabzevari Hamid Madanchi Mohammad Mehdi Ranjbar Seyed Fazlollah Mousavi Ali Akbar Shabani Source Type: research

Design, development, and assessment of a novel multi-peptide vaccine targeting PspC, PsaA, and PhtD proteins of Streptococcus pneumoniae
This report for the first time presents a novel multi-peptide vaccine composed of immunodominant peptides of PspC, PsaA, and PhtD. In general, the experimental results supported the immunoinformatics predictions.PMID:38143051 | DOI:10.1016/j.ijbiomac.2023.128924 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - December 24, 2023 Category: Biochemistry Authors: Zohreh Bahadori Mona Shafaghi Jahangir Sabzevari Hamid Madanchi Mohammad Mehdi Ranjbar Seyed Fazlollah Mousavi Ali Akbar Shabani Source Type: research

An Optional Delinked Reward System: Making Pharmaceutical Innovation Work for Everyone
AbstractConflicts over pharmaceutical pricing are driven by the patients ’ need for affordable medicines and the producer’s reward for the investments in developing innovative medicines. A single price cannot achieve both goals, as it will either obstruct access by patients or provide too low a return to investors. This has led to calls to “delink” the payment fo r innovation from the price paid for drugs, so that both goals can be met efficiently and without conflict. However, the details of how best to do that are unclear. This paper proposes a specific implementation for delinking the Optional Delinked Reward Sy...
Source: Applied Health Economics and Health Policy - December 22, 2023 Category: Health Management Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research

Invasive pneumococcal disease surveillance in Canada, 2020
CONCLUSION: Though the incidence of IPD decreased in 2020 in comparison to previous years across all age groups, disease due to PCV13 serotypes 3 and 4, as well as non-PCV13 serotypes such as 8 and 12F, increased in prevalence. Continued surveillance of IPD is imperative to monitor shifts in serotype distribution and antimicrobial resistance.PMID:38124782 | PMC:PMC10732480 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - December 21, 2023 Category: Infectious Diseases Authors: Alyssa Golden Averil Griffith Walter Demczuk Brigitte Lefebvre Allison McGeer Gregory Tyrrell George Zhanel Julianne Kus Linda Hoang Jessica Minion Paul Van Caeseele Hanan Smadi David Haldane George Zahariadis Kristen Mead Laura Steven Lori Strudwick Anit Source Type: research