Health State Values of Deaf British Sign Language (BSL) Users in the UK: An Application of the BSL Version of the EQ-5D-5L
AbstractBackgroundDeaf people experience health inequalities compared to hearing populations. The EQ-5D, a widely used, standardised, generic measure of health status, which is available in over 100 languages, was recently translated into British Sign Language (BSL) and initial validation conducted. Using data from this previous study of the EQ-5D-5L BSL we aimed to assess (1) whether responses to the EQ-5D differed between a sample of Deaf BSL users and the general population (2) whether socio-demographic characteristics and clinical measures were associated with EQ-5D index scores in Deaf BSL users and (3) the impact of ...
Source: Applied Health Economics and Health Policy - January 16, 2020 Category: Health Management Source Type: research

Correction to: Cost Effectiveness of Cladribine Tablets for the Treatment of Relapsing-Remitting Multiple Sclerosis in The Netherlands
The second author ’s name should be “Maria De Francesco” rather than “Maria de Fransesco”. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 14, 2020 Category: Health Management Source Type: research

Comparison of Utilization Trends between Biosimilars and Generics: Lessons from the Nationwide Claims Data in South Korea
ConclusionBiosimilars captured the market rapidly, despite a heterogeneous uptake rate by product in South Korea. However, expansion of biosimilar use in the market and consequent expenditure savings need to be supported by pre-emptive policy measures to encourage price competition and boost utilization. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 13, 2020 Category: Health Management Source Type: research

Do Research Groups Align on an Intervention ’s Value? Concordance of Cost-Effectiveness Findings Between the Institute for Clinical and Economic Review and Other Health System Stakeholders
AbstractThe Institute for Clinical and Economic Review (ICER) employs fixed cost-effectiveness (CE) thresholds that guide their appraisal of an intervention ’s long-term economic value. Given ICER’s rising influence in the healthcare field, we undertook an assessment of the concordance of ICER’s CE findings to the published CE findings from other research groups (i.e., “non-ICER” researchers including life science manufacturers, academics, and government institutions). Disease areas and pharmaceutical interventions for comparison were determined based on ICER evaluations conducted from 1 Janua...
Source: Applied Health Economics and Health Policy - January 10, 2020 Category: Health Management Source Type: research

The Impact of Physicians ’ Working Hours on Inappropriate Use of Outpatient Medicine in a Tertiary Hospital in China
ConclusionsLonger working hours are a risk factor for inappropriate prescribing. Relevant interventions are urgently needed to establish working hour limits in China to reduce the likelihood of inappropriate prescribing by physicians. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 27, 2019 Category: Health Management Source Type: research

iFuse Implant System for Treating Chronic Sacroiliac Joint Pain: A NICE Medical Technology Guidance
AbstractTreatment and management of sacroiliac joint pain is often non-surgical, involving packages of care that can include analgesics, physiotherapy, corticosteroid injections and radiofrequency ablation. Surgical intervention is considered when patients no longer respond to conservative management. The iFuse Implant System is placed across the sacroiliac joint using minimally invasive surgery, stabilising the joint and correcting any misalignment or weakness that can cause chronic pain. The iFuse system was evaluated in 2018 by the UK National Institute for Health and Care Excellence (NICE) as part of the Medical Techno...
Source: Applied Health Economics and Health Policy - December 27, 2019 Category: Health Management Source Type: research

Comment on: “Projections of the Healthcare Costs and Disease Burden due to Hepatitis C Infection Under Different Treatment Policies in Malaysia, 2018–2040”
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 19, 2019 Category: Health Management Source Type: research

Cost-Effectiveness of Extended and One-Time Screening Versus No Screening for Non-Valvular Atrial Fibrillation in the USA
ConclusionsOur analysis suggests that, screening the general population at age 75  years for NVAF is cost effective at a WTP threshold of $100,000. Both extended screening and one-time screening for NVAF are expected to provide health benefits at an acceptable cost. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 17, 2019 Category: Health Management Source Type: research

Incorporating the Environmental Impact into a Budget Impact Analysis: The Example of Adopting RESPIMAT ® Re-usable Inhaler
ConclusionsAdopting RESPIMAT® re-usable to the national healthcare services may be a cost-saving option, which has the additional benefit of reducing the societal cost of carbon emissions. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 6, 2019 Category: Health Management Source Type: research

The Relevant Perspective of Economic Evaluations Informing Local Decision Makers: An Exploration in Weight Loss Services
AbstractSince 2013, obesity services in the UK National Health Service (NHS) have focused on a tiered structure, with tiers 3 (specialist weight management services) and 4 (primarily bariatric surgery) commissioned by Clinical Commissioning Groups (CCGs) and widely reported as cost effective and recommended by national guidelines. However, CCGs have been reluctant to fully conform to the guidance. We explore how the different evaluative perspective of those generating evidence from local decision makers has contributed to this failure of the CCGs to provide services considered cost effective. We explore four elements where...
Source: Applied Health Economics and Health Policy - December 4, 2019 Category: Health Management Source Type: research

Value-Based Pricing Alternatives for Personalised Drugs: Implications of Asymmetric Information and Competition
AbstractThe market for new drugs is changing: personalised drugs will increase the heterogeneity in patients ’ responses and, possibly, costs. In this context, price regulation will play an increasingly important role. In this article, we argue that personalised medicine opens new scenarios in the relationship between value-based prices, regulation and industry listing strategies. Our focus is on the rol e of asymmetry of information and competition. We show that, if the firm has more information than the payer on the heterogeneity in patients’ responses and it adopts a profit-maximising listing strategy, the o...
Source: Applied Health Economics and Health Policy - December 2, 2019 Category: Health Management Source Type: research

The Evolution of Mental Health in the Context of Transitory Economic Changes
ConclusionEven though the need for mental healthcare increased during the recession, the fact that fewer people were diagnosed suggests that barriers to accessing mental healthcare may be aggravated during the crisis. Policies aiming to tackle the challenges posed by the high prevalence of mental disorders have to be particularly attentive to changes in individuals ’ socioeconomic situation, including education, unemployment and social class. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 25, 2019 Category: Health Management Source Type: research

Constrained Optimization for the Selection of Influenza Vaccines to Maximize the Population Benefit: A Demonstration Project
ConclusionSignificant gains in cost efficiency can be realized for a decision maker using a CO model, especially for a disease like influenza with many vaccine options. Testing the model under different scenarios offers powerful insights into maximum achievable benefit overall and per age group within the predefined constraints of a vaccine budget. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 22, 2019 Category: Health Management Source Type: research

Systematic Review of Economic Evaluations of Services Provided by Community Pharmacists
ConclusionsOur findings suggest there are various issues related to the quality of conduct and reporting of economic evaluations of services provided by community pharmacists. Interpretation of these studies should be treated with caution to facilitate decision making in the local context. In an era of scarce resources and demand for evidence-informed decision making, there may be a need for guidance on methodological approaches to assess the value of these services. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 21, 2019 Category: Health Management Source Type: research

Cost-Effectiveness of Therapeutic Use of Safety-Engineered Syringes in Healthcare Facilities in India
ConclusionRUP syringes are estimated to be cost-effective in the Indian context. SIP and RUP  + SIP syringes are not cost-effective at the current unit prices. Efforts should be made to bring down the price of SES to improve its cost-effectiveness. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 19, 2019 Category: Health Management Source Type: research

Forecasting Ontario Oncology Drug Expenditures: A Hybrid Approach to Improving Accuracy
AbstractBackgroundThe Provincial Drug Reimbursement Program (PDRP) at Cancer Care Ontario (CCO) is responsible for monitoring actual and projected outpatient intravenous cancer drug spending in the province. We developed a hybrid forecasting approach combining automated time-series forecasting with expert-customizable input.ObjectiveOur objectives were to provide a flexible tool in which to incorporate multiple forecasts and to improve the accuracy of the resulting forecast.MethodsThe approach employed linear and non-linear time-series techniques and a combined hybrid model incorporating both approaches. We developed an in...
Source: Applied Health Economics and Health Policy - November 14, 2019 Category: Health Management Source Type: research

Healthcare Costs for People with Serious Mental Illness in England: An Analysis of Costs Across Primary Care, Hospital Care, and Specialist Mental Healthcare
ConclusionsAnnual healthcare costs for people with SMI vary significantly across clinical and socioeconomic characteristics and healthcare sectors. This analysis informs policy and research, including estimation of health budgets for particular patient profiles, and economic evaluation of health services and policies. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 8, 2019 Category: Health Management Source Type: research

Cost-Effectiveness of Dementia Care Mapping in Care-Home Settings: Evaluation of a Randomised Controlled Trial
AbstractBackgroundBehaviours such as agitation impact on the quality of life of care-home residents with dementia and increase healthcare use. Interventions to prevent these behaviours have little evidence supporting their effectiveness or cost-effectiveness. We conducted an economic evaluation alongside a trial assessing Dementia Care Mapping ™ (DCM) versus usual care for reducing agitation, and highlight methodological challenges of conducting evaluations in this population and setting.MethodsRCT data over 16  months from English care-home residents with dementia (interventionn = 418; controln&th...
Source: Applied Health Economics and Health Policy - November 8, 2019 Category: Health Management Source Type: research

Cost Effectiveness of Secukinumab Versus Other Biologics and Apremilast in the Treatment of Active Psoriatic Arthritis in Germany
ConclusionsSecukinumab appears to be cost effective compared with other DMARDs for the treatment of active PsA in biologic-na ïve and biologic-experienced populations in Germany. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 7, 2019 Category: Health Management Source Type: research

Time to Review Authorisation and Funding for New Cancer Medicines in Europe? Inferences from the Case of Olaratumab
AbstractThe potential benefits of early patient access to new medicines in areas of high unmet medical need are recognised, but uncertainties concerning effectiveness, safety and added value when new medicines are authorised, and subsequently funded based on initial preliminary data only, have important implications. In 2016 olaratumab received accelerated conditional approval from both the European Medicines Agency and the US Food and Drug Administration for the treatment of soft-tissue sarcoma, based on the claims of a substantial reduction in the risk of death with an 11.8-month improvement in median overall survival in...
Source: Applied Health Economics and Health Policy - November 7, 2019 Category: Health Management Source Type: research

Socioeconomic Disparities in Unmet Need for Student Mental Health Services in Higher Education
ConclusionSocioeconomic disparities in unmet need are driven by higher rates of mental ill-health among those from lower socioeconomic backgrounds. Our findings have implications for the targeting of services, as well as the provision of information about mental health and associated services. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 5, 2019 Category: Health Management Source Type: research

Cost-utility Analysis of Opportunistic and Systematic Diabetic Retinopathy Screening Strategies from the Perspective of the Brazilian Public Healthcare System
ConclusionSystematic teleophthalmology-based DR screening for the Brazilian population with T2D would be considered very cost effective compared to the opportunistic ophthalmology referral-based screening according to the WHO-WTP threshold. However, there is still a considerable amount of uncertainty around the results. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - November 1, 2019 Category: Health Management Source Type: research

Acknowledgement to Referees
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 29, 2019 Category: Health Management Source Type: research

An Alternative Approach to Decomposing the Redistributive Effect of Health Financing Between and Within Groups Using the Gini Index: The Case of Out-of-Pocket Payments in Nigeria
AbstractEquity in health financing remains significant in the universal health coverage discourse. The way a health system is financed, apart from determining whether people have access to needed health services, also has implications for income inequality in a country. Traditionally, the impact of health financing on income inequality or the redistributive effect of health financing is assessed by looking at whether income inequality reduces because of health financing. This is also decomposed into a vertical component (the extent of progressivity), a horizontal component (the extent to which households with similar incom...
Source: Applied Health Economics and Health Policy - October 18, 2019 Category: Health Management Source Type: research

Implicitly Estimating the Cost of Mental Illness in Australia: A Standard-of-Living Approach
ConclusionPeople with mental illness need to increase equivalised disposable income, which includes existing financial supports, by 50 –80% to achieve a similar level of financial satisfaction to those without a mental illness. The cost estimate can be substantially higher if the overall life satisfaction is used to proxy for standard of living. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 17, 2019 Category: Health Management Source Type: research

Universal Mental Health Interventions for Children and Adolescents: A Systematic Review of Health Economic Evaluations
ConclusionFew studies were found, which limits the possibility of drawing strong conclusions about cost effectiveness. There is some evidence based on decision-analytic modelling that anti-bullying interventions represent value for money. Generally, there is a lack of studies that take into account long-term costs and effects.Systematic Review Registration NumberCRD42019115882. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 12, 2019 Category: Health Management Source Type: research

Expanding the Role of the Patient-Centered Outcomes Research Institute: Reauthorization and Facilitating Value Assessments
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 5, 2019 Category: Health Management Source Type: research

Estimating Attribute-Specific Willingness-to-Pay Values from a Health Care Contingent Valuation Study: A Best –Worst Choice Approach
ConclusionOur BWC-CV framework may serve as a valuable alternative for estimating marginal WTP values for health care attributes when the choice behavior of respondents raises concerns for the validity of DCE estimates. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 28, 2019 Category: Health Management Source Type: research

Using the Threshold Technique to Elicit Patient Preferences: An Introduction to the Method and an Overview of Existing Empirical Applications
AbstractPatient preference information (PPI) is a topic of interest to regulators and industry. One of many known methods for eliciting PPI is the threshold technique (TT). However, empirical studies of the TT differ from each other in many ways and no effort to date has been made to summarize them or the evidence regarding the performance of the method. We sought to describe the TT and summarize the empirical applications of the method. Forty-three studies were reviewed. Most studies estimated the minimum level of benefit required to make a treatment worthwhile, and over half estimated the maximum level of risk patients w...
Source: Applied Health Economics and Health Policy - September 20, 2019 Category: Health Management Source Type: research

Determining the Baseline Strategy in a Cost-Effectiveness Analysis with Treatment Sequences
This study investigated the impact of the baseline strategy on the cost-effectiveness results, when a sequence of treatments was used. First, we reviewed submissions to the UK National Institute for Health and Care and Excellence to understand how economic models that used comparisons of treatment sequences defined the baseline strategy. We then built a simple Markov model to use as a case study. The analysis we conducted contained four hypothetical treatments of varying cost-effectiveness relationships to a fixed control (best supportive care): Treatment A was cost effective, Treatment B was extendedly dominated by Treatm...
Source: Applied Health Economics and Health Policy - September 20, 2019 Category: Health Management Source Type: research

A Multinational European Study of Patient Preferences for Novel Diagnostics to Manage  Antimicrobial Resistance
ConclusionPatients in different European countries do not have the same preferences for the attributes of diagnostic tests to manage AMR in primary care. Failure to account for such differences during test development could reduce test uptake, result in continued overuse of antibiotics, and hamper marketisation. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 20, 2019 Category: Health Management Source Type: research

Assessing Horizontal Equity in the Utilization of Mental Healthcare Services in Turkey: A Gender Perspective
ConclusionsThere is a great need for gender-focused policies to improve horizontal equity in mental healthcare services utilization. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 18, 2019 Category: Health Management Source Type: research

Evaluating the Cost Effectiveness of a Suicide Prevention Campaign Implemented in Ontario, Canada
AbstractBackgroundAlthough suicide-prevention campaigns have been implemented in numerous countries, Canada has yet to implement a strategy nationally. This is the first study to examine the cost utility of the implementation of a multidimensional suicide-prevention program that combines several interventions over a 50-year time horizon.MethodsWe used Markov modeling to capture the dynamic changes to health status and estimate the incremental cost per quality-adjusted life-year gained over a 50-year period for Ontario residents for a suicide-prevention strategy compared to no intervention. The strategy consisted of a packa...
Source: Applied Health Economics and Health Policy - September 18, 2019 Category: Health Management Source Type: research

Why Do Informal Sector Workers Not Pay the Premium Regularly? Evidence from the National Health Insurance System in Indonesia
ConclusionAlthough there is no single policy that can ensure that informal sector workers (PBPU members) regularly pay their premiums, this study recommends some policy interventions, including (1) flexibility in applying for a government subsidy for premiums (Penerima Bantuan Iuran [PBI]), especially for people who have financial hardship; (2)  an intensive promotion of insurance literacy; (3) expanding the quantity and quality of healthcare services; and (4) tailor-made policies for ensuring the sustainability of premium payments for each regional division. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 18, 2019 Category: Health Management Source Type: research

Price Models for Multi-indication Drugs: A Systematic Review
ConclusionsThere are no applications of pure IBP systems and their practical consequences are therefore unknown. More economic theory-based assessments of the pros and cons of IBP and studies different from reviews are needed to capture their intricacies and specificities. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 16, 2019 Category: Health Management Source Type: research

An Assessment of Domestic Financing for Reproductive, Maternal, Neonatal and Child Health in Sub-Saharan Africa: Potential Gains and Fiscal Space
ConclusionThis result reinforces calls for increased domestic financing for health through innovations in domestic resource mobilization. Improving the performance of tax systems will be a step in the right direction, with possible long-term gains to the health sector. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 12, 2019 Category: Health Management Source Type: research

A Review of the Development and Application of Generic Preference-Based Instruments with the Older Population
This article reviews the development and application of these instruments within the older population and discusses the issues surrounding their use with this population. Areas for further research relating to the development and application of generic preference-based instruments wit h populations of older people are also highlighted. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 12, 2019 Category: Health Management Source Type: research

Financial Burden of Prescribed Medicines Included in Outpatient Benefits Package Schemes: Comparative Analysis of Co-Payments for Reimbursable Medicines in European Countries
ConclusionsCo-payments for prescribed medicines can pose a substantial financial burden for outpatients, particularly in lower-income countries. The price of a medicine, availability of lower-priced medicines and the design of co-payments, including exemptions and reductions for specific groups, can considerably impact patients ’ expenses for medicines. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - September 11, 2019 Category: Health Management Source Type: research

The Impact of Ghana ’s National Health Insurance on Psychological Distress
AbstractBackgroundPoor mental health is among the growing number of noncommunicable diseases in low- and middle-income countries. Despite poor mental health accounting for an already considerable and growing burden of disease in many low- and middle-income countries, policy action to confront the challenge has been limited, at both international and national levels. Recently, several low- and middle-income countries have embarked on the journey toward universal health coverage by expanding their public health insurance provision, with the ultimate objective of improving population health, in addition to other health system...
Source: Applied Health Economics and Health Policy - September 9, 2019 Category: Health Management Source Type: research

A Review of Recent Decision-Analytic Models Used to Evaluate the Economic Value of Cancer Treatments
This study summarises the key modelling approaches considered in oncology, alongside their advantages and limitations. A review was conducted to identify single technology appraisals (STAs) submitted to the National Institute for Health and Care Excellence (NICE) and published papers reporting full economic evaluations of cancer treatments published within the last 5  years. The review was supplemented with the existing methods literature discussing cancer modelling. In total, 100 NICE STAs and 124 published studies were included. Partitioned-survival analysis (n = 54) and discrete-time state transition stru...
Source: Applied Health Economics and Health Policy - September 4, 2019 Category: Health Management Source Type: research

Cost Effectiveness of Cladribine Tablets for the Treatment of Relapsing-Remitting Multiple Sclerosis in The Netherlands
ConclusionsThe base-case analysis shows that treatment of RRMS with cladribine tablets is cost effective versus alemtuzumab and fingolimod in HDA patients, and cost effective versus natalizumab in RES patients, at a threshold of €50,000. Driven by the lower costs, cladribine tablets were cost effective (dominant) in all base-case analyses. However, given that outcomes are based on indirect comparisons and post hoc subgroup analysis, as well as the uncertainty surrounding the outcomes, the results presented in this paper s hould be interpreted with caution. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - August 23, 2019 Category: Health Management Source Type: research

Analyzing the Financial Sustainability of User Fee Removal Policies: A Rapid First Assessment Methodology with a Practical Application for Burkina Faso
AbstractThe purpose of this paper is to briefly present a methodological framework that does not require cumbersome investigations for a first assessment of the financial sustainability of policies aiming to remove or reduce healthcare user fees (the so-called free healthcare policy [FHCP]). This paper is organized in two main sections. The first analyzes the various possibilities available to finance an FHCP. Using several scenarios, it includes a special focus devoted to the calculus of what to consider when assessing the sustainability of expanding fiscal space for financing the FHCP. The second section relies on the cu...
Source: Applied Health Economics and Health Policy - August 21, 2019 Category: Health Management Source Type: research

Improving Decision-Making Processes in Health: Is It Time for (Disease-Specific) Reference Models?
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - August 20, 2019 Category: Health Management Source Type: research

The Value Employees Place on Health Insurance Plans: A Discrete-Choice Experiment
This study examined the values that single adults with employer-based coverage place on health insurance plan attributes using a discrete-choice experiment (DCE).MethodsAs part of an online survey, each respondent completed 28 paired comparisons trading off four attributes: source of coverage, plan type, monthly out-of-pocket premium, and quality of coverage.ResultsBased on our results (N = 2207), single employees slightly preferred their employer over the Marketplace as a source of coverage (0.726 odds ratio;p value  
Source: Applied Health Economics and Health Policy - August 19, 2019 Category: Health Management Source Type: research

Program Evaluation and Decision Analytic Modelling of Universal Suicide Prevention Training (safeTALK) in Secondary Schools
This study aims to evaluate a suicide awareness training (safeTALK) and to model potential return on investment (ROI) on a population basis. SafeTALK, comprises a 3-h education session, and has been delivered to secondary school students (aged 15 –16 years) in Mackay, located in the Australian state of Queensland.MethodsEvaluation consisted of two phases, ex-post and ex-ante. Phase I was a pre-post, follow-up analysis using a mixed-method questionnaire administered immediately prior (Time 1), immediately after (Time 2), and 4  weeks after training (Time 3). Phase II involved decision analytic modelling comp...
Source: Applied Health Economics and Health Policy - August 14, 2019 Category: Health Management Source Type: research

Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting
ConclusionsThe HMGA2 test is estimated to improve leukemia-free survival and overall survival outcomes, and yield costs savings from a healthcare system and societal perspective. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - August 7, 2019 Category: Health Management Source Type: research

In-Hospital Healthcare Utilization, Outcomes, and Costs in Pre-Hospital-Adjudicated Low-Risk Chest-Pain Patients
ConclusionIn low-risk chest-pain patients according to pre-hospital risk assessment, acute healthcare utilization and costs are high, with limited added value. Possibly, if a complete risk assessment can be performed by ambulance paramedics, acute hospitalization of the majority of low-risk patients is not necessary, which can lead to substantial cost reduction.Trial IDDutch Trial Register [http://www.trialregister.nl]: trial number 4205. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - August 6, 2019 Category: Health Management Source Type: research

What Does Society Value About Cancer Medicines? A Discrete Choice Experiment in the Belgian Population
ConclusionsThis study has shown that gain in quality of life with cancer medicines is valued higher by Belgian society for patients who have lower initial quality of life before the start of treatment. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - July 30, 2019 Category: Health Management Source Type: research

Health Insurance in Sub-Saharan Africa: A Scoping Review of the Methods Used to Evaluate its Impact
AbstractWe conducted a scoping review with the objective of synthesizing available literature and mapping what designs and methods have been used to evaluate health insurance reforms in sub-Saharan Africa. We systematically searched for scientific and grey literature in English and French published between 1980 and 2017 using a combination of three key concepts: “Insurance” and “Impact evaluation” and “sub-Saharan Africa”. The search led to the inclusion of 66 articles with half of the studies pertaining to the evaluation of National Health Insurance schemes, especially the Ghanaian one,...
Source: Applied Health Economics and Health Policy - July 30, 2019 Category: Health Management Source Type: research

Cost-Effectiveness of a School-Based Social and Emotional Learning Intervention: Evidence from a Cluster-Randomised Controlled Trial of the Promoting Alternative Thinking Strategies Curriculum
ConclusionThe PATHS curriculum has the potential to be cost effective at standard UK willingness-to-pay thresholds. However, the sensitivity of the cost-effectiveness estimates to key assumptions means decision makers should seek further information before allocating scarce public resources.Trial registration numberISRCTN85087674. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - July 26, 2019 Category: Health Management Source Type: research