Applied Health Economics and Health Policy
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Medication Adherence and Healthcare Costs in Chronically Ill Patients Using German Claims Data
ConclusionsThe estimated effect on total costs differed from most other studies, which highlights concerns about generalizability, although effect estimates in sub-categories were as expected. Comparison of time lags indicates the importance of avoiding concurrent measurement. A non-linear relationship should be considered. These methodological approaches are valuable in future research on adherence and its consequences. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - March 18, 2023 Category: Health Management Source Type: research
Economic Evaluation of Evusheld for Preexposure Prevention of COVID-19 in High-Risk Populations: Early Evidence from Thailand
ConclusionAmong three COVID-19-vaccinated immunocompromised patient populations, this study concluded that Evusheld was cost-effective for dialysis patients with inadequate immune response to the COVID-19 vaccine. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - March 16, 2023 Category: Health Management Source Type: research
Review and Assessment of Policy Options for Improving Access to Combination Therapies in Oncology in Europe
ConclusionsThere is a growing need to ensure that CTs are affordable to health systems. It would appear that there is no one set of policies that is appropriate for all countries in Europe, so countries wishing to ensure that patients have (or continue to have) access to CTs of value to them must explore and implement the policies that are best suited to their general approach to funding health care and to the assessment and reimbursement of medicines. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - March 10, 2023 Category: Health Management Source Type: research
Stakeholder Engagement in the Development of Public Health Economic Models: An Application to Modelling of Minimum Unit Pricing of Alcohol in South Africa
ConclusionsOur programme of stakeholder engagement was fully integrated into the research programme. It resulted in a number of benefits including creating positive working relationships, guiding modelling decisions, tailoring the research to the context, and providing ongoing opportunities for communication. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - March 9, 2023 Category: Health Management Source Type: research
Modelling Methods of Economic Evaluations of HIV Testing Strategies in Sub-Saharan Africa: A Systematic Review
ConclusionsThis review is the first to synthesise economic evaluations of HIV testing strategies in sub-Saharan Africa. The majority of models exhibited dynamic, stochastic and individual properties. Model reporting against the 13 criteria in our novel tool was mixed. Future model-based economic evaluations of HIV testing strategies would benefit from transparency around the choice of modelling approach, model structure, data handling procedures and model validation techniques. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - February 28, 2023 Category: Health Management Source Type: research
An Investigation into the Relationship Between Choice of Model Structure and How to Adjust for Subsequent Therapies Using a Case Study in Oncology
ConclusionsThe simplicity of the PartSA is lost when the decision problem becomes more complex (for example, when OS data are confounded by subsequent therapies). In this setting, the MSM structure may be considered more flexible, with fewer and less restrictive assumptions required versus the PartSA. Researchers should consider important study design features that may influence the generalisability of data when undertaking model conceptualisation. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - February 27, 2023 Category: Health Management Source Type: research
Global Pull Incentives for Better Antibacterials: The UK Leads the Way
(Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - February 11, 2023 Category: Health Management Source Type: research
The Impact of Value-Based Payment Models for Networks of Care and Transmural Care: A Systematic Literature Review
ConclusionsThe overall positive effect on clinical and cost outcomes validates the success of VBP models. The mostly negative effects on organization-reported outcomes/experiences are corroborated by findings regarding providers ’ lack of awareness, trust, and engagement with the model. This may be justified by their exclusion from the design of the models, decreasing their sense of ownership and, therefore, motivation. Incentives, targets, benchmarks, and quality measures, if adequately designed, seem to be important fac ilitators, and if lacking or inadequate, they are key inhibitors. These are prominent facilitators a...
Source: Applied Health Economics and Health Policy - February 1, 2023 Category: Health Management Source Type: research
A Systematic Review of Health Economic Evaluations and Budget Impact Analyses to Inform Healthcare Decision-Making in Central America
ConclusionIn Central America, health economic research is sparse and is considered as suboptimal quality for reporting. The findings reported information useful to other low- and middle-income countries with similar advances in the application of economics to promote health policy decision-making. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 31, 2023 Category: Health Management Source Type: research
The Impact of Suboxone ’s Market Exclusivity on Cost of Opioid Use Disorder Treatment
ConclusionsUnmerited 6 years of market exclusivity for brand-name buprenorphine-naloxone in Canada resulted in substantial excess costs. There is an urgent need to implement policies that can help reduce costs for high-priority drugs in Canada. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 18, 2023 Category: Health Management Source Type: research
Can the UK ‘Netflix’ Payment Model Boost the Antibacterial Pipeline?
This article describes how the project was devised, developed, and progressed. The learning from this work might help other countries to adopt or adapt the approach to fit wi th their national systems, and collectively achieve a global incentive to reinvigorate the antibacterial pipeline. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 17, 2023 Category: Health Management Source Type: research
Cost Effectiveness of Denosumab for Secondary Prevention of Osteoporotic Fractures Among Postmenopausal Women in China: An Individual-Level Simulation Analysis
ConclusionsDenosumab is not cost effective for preventing secondary fractures among overall postmenopausal women in China. It is advisable to identify alternative denosumab regimens for high-risk subgroups among previously fractured postmenopausal women. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 10, 2023 Category: Health Management Source Type: research
Development of an Instrument for the Assessment of Health-Related Multi-sectoral Resource Use in Europe: The PECUNIA RUM
ConclusionThis is the first study that transparently describes the development process of a generic multi-sectoral RUM instrument in health economics and provides insights into the methodological aspects and overall validity of its development process. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 9, 2023 Category: Health Management Source Type: research
Conditional Funding Recommendations for Drugs in Canada: A Cross-Sectional Analysis
ConclusionsCADTH has facilitated patient access to innovative drugs even with limited evidence by conditional recommendations. The clinical criteria are the cornerstone of conditional recommendations. CADTH has developed the assessment process over time. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - January 7, 2023 Category: Health Management Source Type: research
Headroom Analysis for Early Economic Evaluation: A Systematic Review
ConclusionsBecause the application of the headroom analysis varies considerably, we recommend its appropriate use and clear reporting of analytical approaches, level of evidence available, and the use of expert judgement. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - December 28, 2022 Category: Health Management Source Type: research