Coronavirus and People with Intellectual Disabilities: A Special Perspective.
Authors: Tenenbaum A, Glasbauer D, Wexler ID Abstract BACKGROUND: The attention of the world is focused on the coronavirus disease-2019 (COVID-19) pandemic. There is s general awareness that certain population groups are at greater risk. However, some other populations may be transparent and may not be receiving the attention they warrant. We focused on those with intellectual disability explaining why they are vulnerable during the current pandemic and require special attention. PMID: 33443333 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Convalescent Whole Blood Donors Screening Strategies for Providing Efficient and Safe COVID-19 Survivors' Plasma and Other Blood Components.
CONCLUSIONS: Blood component units from recovering COVID-19 patients are safe. Plasma units with positive IgG antibodies could serve as an efficient passive immunization for COVID-19 patients. Moreover, in the face of increased transfusion demand for treatment of anemia and coagulation dysfunction in critical ill COVID-19 patients, red blood cells units and random platelets units from convalescent donors can be safely transfused. PMID: 33443334 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Self-reported changes in use of addictive substances and behaviors among patients treated in an addiction treatment clinic during the COVID-19 quarantine.
Authors: Lev Bar-Or R, Shalit N, Shpitzer R, Kor A, Lev-Ran S PMID: 33443335 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Impact of Dietary Modifications and Medical Management on 24-Hour Urinary Metabolic Profiles and the Status of Renal Stone Disease in Recurrent Stone Formers.
CONCLUSIONS: Dietary modifications and medical management significantly aid in correcting urinary metabolic abnormalities. Consequently, reduced nehprolithiasis-related events and better stone burden control is expected. PMID: 33443336 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Sex Differences in Folate Levels: A Cross Sectional Study of a Large Cohort from Israel.
Authors: Cohen E, Margalit I, Shochat T, Goldberg E, Krause I Abstract BACKGROUND: Low folate levels are associated with megaloblastic anemia, neural tube defects, and an increased risk of cancer. Data are scarce regarding the sex aspect of this deficiency. OBJECTIVES: To assess sex differences in folate levels in a large cohort of patients and to investigate the effect of low folate levels on homocysteine concentrations. METHODS: Data were collected from medical records of patients examined at a screening center in Israel between 2000 and 2014. Cross sectional analysis was conducted on 9214 males and 4336 ...
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

An Assessment of the Completeness and Timeliness of the Israel National Cancer Registry.
CONCLUSIONS: Completeness and timeliness of the INCR are high and meet international guidelines. Fully automated reporting will likely improve the quality and timeliness of INCR data. PMID: 33443338 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Changing Paradigms in Below-the-Knee Arterial Interventions: Are We Saving Legs?
Authors: Silverberg D, Hater H, Sonqrot H, Raskin D, Khaitovich B, Halak M Abstract BACKGROUND: Patients with critical limb ischemia (CLI) involving the below-the-knee (BTK) arteries are at increased risk of limb loss. Despite improvement in endovascular modalities, it is still unclear whether an aggressive approach results in improved limb salvage. OBJECTIVES: To assess whether an aggressive approach to BTK arterial disease results in improved limb salvage. METHODS: A comparative study of two groups was conducted. Group 1 included patients treated between 2012 and 2014, primarily with transfemoral angiopla...
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Morphological and Histological Changes in the Human Anterior Cruciate Ligament after Rupture.
CONCLUSIONS: The morphological features of the ACL remnant in the first 3 months after injury showed no scar tissue and its histological features had the characteristics of a reparative phase. This phase was followed by a prolonged remodeling phase that ended with attachment of the remnant to the posterior cruciate ligament. PMID: 33443340 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

European Registry on Helicobacter pylori management (Hp-EuReg): First-line Therapy in Israel.
Authors: Boltin D, Beniashvili Z, Lahat A, Hirsch J, Nyssen OP, Mégraud F, O'Morain C, Gisbert JP, Niv Y Abstract BACKGROUND: The antibiotic resistance profile of Helicobacter pylori (H. pylori) is constantly changing. Up-to-date and reliable data for the effectiveness of first-line H. pylori treatment protocols are necessary to provide evidence-based best-practice guidelines. OBJECTIVES: To determine the effectiveness, compliance and safety of first-line treatment for H. pylori in Israel. METHODS: An observational, prospective, multicenter study was conducted in tertiary referral centers in Israel, ...
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Factors Associated with More Than 500 Grams Inaccuracy in Sonographic Fetal Weight Estimation.
Authors: Hendin N, Levin G, Tsur A, Ilan H, Rottenstreich A, Meyer R Abstract BACKGROUND: The sonographic assessment of estimated fetal weight (EFW) is essential for identification of fetuses in weight extremes and aids in peripartum management. However, there are inconsistent reports regarding EFW accuracy. OBJECTIVES: To examine maternal and fetal determinants associated with unreliable EFW. METHODS: A retrospective case-control study was conducted at a single, tertiary medical center between 2011 and 2019. All term, singleton deliveries with a sonographic EFW within 2 weeks of delivery were included. Unr...
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Torsion of Functional Adnexal Cysts in Pregnancy: Aspiration and Drainage are Important in Preventing Recurrence.
CONCLUSIONS: Functional ovarian cysts are the most common adnexal pathology encountered in pregnant women with torsion. Intra-operative cyst aspiration and drainage may reduce the risk of recurrent torsion. Further multi-center studies are required to validate our data prospectively. PMID: 33443343 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Intravascular Small Cell Carcinoma Disguised as Pulmonary Embolism.
Authors: Rokach A, Hochberg-Klein S, Arish N, Doviner V, Bar-Shalom R, Turner Y, Heching N, Heyman SN PMID: 33443344 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Stroke Following Cannabis Overuse.
Authors: Levinger U, Hadar S, Habib G PMID: 33443345 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Perichondritis after High Ear Piercing.
Authors: Roguin Maor N, Zmiri P PMID: 33443346 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Respiratory Failure Induced by Vaping-Associated Pulmonary Injury: Case Report of a New Entity.
Authors: Sarel E, Hoppenstein DR, Lahav M, Ifrach N, Fanadka F, Fredman BD PMID: 33443347 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Ileal Perforation in Granulomatosis with Polyangiitis: A Rare Complication.
Authors: Levartovsky A, Gilead R, Sharon A, Pomeranz A, Druyan A, Westrich G, Huber RK, Mayan H, Shilo N PMID: 33443348 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Recurrent Pregnancy Loss: Causes, Controversies, and Treatment.
Authors: Mashiach S PMID: 33443349 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Response to Autoimmune/inflammatory syndrome induced by adjuvant associated with a metal implant in the mouth; explantation was followed by recovery.
Authors: Zohar Y PMID: 33443350 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

ASIA Induced by Adjuvant Associated with a Metal Implant in the Mouth: A Response.
Authors: Shoenfeld Y PMID: 33443351 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 15, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Two Decades of Respiratory Medicine in Israel: Achievements and Perspectives.
Authors: Shulimzon TR, Adir Y PMID: 33381941 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Weaning of Severe COVID-19 Mechanically Ventilated Patients: Experience within a Dedicated Unit in Israel.
CONCLUSIONS: Despite the high mortality of COVID-19 patients who require mechanical ventilation, most of the patients in our cohort were weaned in a relatively short period of time. Further large-scale studies are necessary to assess the cost effectiveness of dedicated COVID-19 departments for ventilator weaning. PMID: 33381942 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Catheter Injectable Hydrogel-Based Scaffolds for Tissue Engineering Applications in lung disease.
CONCLUSIONS: The catheter-injectable gelatin-alginate hydrogel represents a new concept, which combines tissue engineering with minimal invasive procedure. It is an inexpensive and convenient to use alternative to other types of suggested scaffolds for lung tissue engineering. This novel concept may be used for additional clinical applications in regenerative medicine. PMID: 33381943 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Lung Transplantation in Idiopathic Pulmonary Fibrosis: Risk Factors and Outcome.
CONCLUSIONS: IPF patients with higher mean PHT, older age (> 65 years), and desaturation following 6MWT had lower survival rates following LTx. DLT may decrease survival rate compared to SLT just for the short and medium period of time after LTx. These results may lead to better selection of IPF patient candidates for LTx. Additional studies are warranted for choosing which patients will have better prognosis after LTx. PMID: 33381944 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Clinical and Radiological Characteristics of Patients Diagnosed with Spontaneous Pneumothorax: Treatment Options and Clinical Outcomes. A Retrospective Analysis 2004 to 2017.
Authors: Erez D, Israeli-Shani L, Epstein Shochet G, King DA, Abu-Akel M, Dovrish Z, Shitrit D Abstract BACKGROUND: Primary spontaneous pneumothorax (PSP) tends to occur in young adults without underlying lung diseases and is usually followed by limited symptoms, while secondary spontaneous pneumothorax (SSP) is a complication of a pre-existing lung disease. Surprisingly, for such common conditions, there is a considerable inconsistency regarding management guidelines. OBJECTIVES: To evaluate the risk factors for spontaneous pneumothoraxes and to summarize outcomes and complications based on our clinical experi...
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Balloon Pulmonary Angioplasty for Inoperable Chronic Thromboembolic Pulmonary Hypertension: First Experience at the Israeli National CTEPH Referral Center.
CONCLUSIONS: We successfully established BPA as a treatment for inoperable CTEPH in our center. BPA resulted in hemodynamic and clinical improvements that were sustained over time. PMID: 33381946 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Fiberoptic Bronchoscopic Submucosal Injection of Mitomycin C for Recurrent Bening Tracheal Stenosis: A Case Series.
CONCLUSIONS: The efficacy of MyC injection should be studied prospectively. PMID: 33381947 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Effect of a Multidisciplinary Integrated Approach on Outcomes in Chronic Obstructive Pulmonary Disease.
CONCLUSIONS: Multidisciplinary approach is feasible and efficacious in patients with COPD. PMID: 33381948 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Computed Tomography-Guided Lung Biopsy: Does a Rural Hospital Do Better?
CONCLUSIONS: CT-guided percutaneous lung biopsies are comparable between rural and urban hospitals regarding procedure characteristics and complication rates. PMID: 33381949 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Advanced Lung Disease in Patients with Cystic Fibrosis Is Associated with Low Diffusion capacity.
CONCLUSIONS: The 10- second perfusion time of the inert gas during DLCOSB represent the communicative alveolar volume in CF patients with advanced pulmonary disease. The findings justify the use of DLCOSB with the deterioration of FEV1 and elevation of pCO2 levels. PMID: 33381950 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

A Review of Symptoms and Complications of Ultrasound Assisted Thoracentesis in the First Specialist Pleural Clinic in Israel.
CONCLUSIONS: Symptoms are a common feature of thoracentesis even when performed by experienced operators in ideal settings. Complications, however, are rare when the procedure is performed with bedside ultrasound and attention is paid to patient-reported symptoms and volume drained. Specialist pleural clinics provide a good model for a standardized approach to safe performance of this common procedure. PMID: 33381951 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Diseases in a Community Medical Center.
CONCLUSIONS: TBC was found to be safe; however, the diagnostic yield was rather low compared to other studies, which emphasizes the need for interstitial lung disease centers with expert in this field. PMID: 33381952 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Early Blood-based Liquid Biopsy in Patients with Treatment-na ïve Metastatic Adenocarcinoma of the Lung: A Case Series.
CONCLUSIONS: These findings suggest that cfDNA analysis should be ordered by the pulmonologists early in the evaluation of patients with NSCLC, which might complement the tumor biopsy. PMID: 33381953 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Rising Incidence of Lung Cancer in Arab Females, Jewish Females, and Arab Males from 1990 to 2014 in Israel.
CONCLUSIONS: Jewish females and Arab males and females living in Israel demonstrated a constant increase in lung cancer incidence, mostly in adenocarcinoma and small cell lung cancer incidence. In addition, a younger age of diagnosis in Arabs was noted. Smoking reduction interventions and screening should be implemented in those populations. PMID: 33381954 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

To Fly Or Not To Fly? Aviation and Respiratory Diseases.
Authors: Abdel-Rahman N, Izbicki G Abstract BACKGROUND: For most passengers, even those with respiratory disease, air travel is safe and comfortable. Some travelers may experience hypoxia at sea level but may not need supplemental oxygen during air travel in a hypobaric hypoxic environment. For some individuals compensatory pulmonary mechanisms may be inadequate, causing profound hypoxia. In addition, venous thromboembolism/pulmonary emboli may occur, especially during long haul flights. With adequate screening, patients at risk can be identified, therapeutic solutions can be proposed for the flight, and most can t...
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Minimally Invasive Surgery of Orbital Apex.
Authors: Shemesh R, Ben Simon GJ, Bedrin L, Yakirevitch A PMID: 33381956 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 1, 2021 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Treating Epilepsy Patients with Investigational Anti-COVID-19 Drugs: Recommendations by the Israeli Chapter of the ILAE.
Authors: Ekstein D, Noyman I, Fahoum F, Herskovitz M, Linder I, Ben Zeev B, Eyal S Abstract BACKGROUND: The coronavirus disease-2019 (COVID-19) and its management in patients with epilepsy can be complex. Prescribers should consider potential effects of investigational anti-COVID-19 drugs on seizures, immunomodulation by anti-seizure medications (ASMs), changes in ASM pharmacokinetics, and the potential for drug-drug interactions (DDIs). The goal of the Board of the Israeli League Against Epilepsy (the Israeli Chapter of the International League Against Epilepsy, ILAE) was to summarize the main principles of the ph...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Impact of the COVID-19 Pandemic on General Surgery Acute Admissions and Urgent Operations: A Comparative Prospective Study.
Authors: Aviran E, Laks S, Benvenisti H, Khalilieh S, Assaf D, Aviran N, Hazzan D, Klein Y, Cohen A, Gutman M, Nissan A, Segev L Abstract BACKGROUND: As part of the effort to control the coronavirus disease-19 (COVID-19) outbreak, strict emergency measures, including prolonged national curfews, have been imposed. Even in countries where healthcare systems still functioned, patients avoided visiting emergency departments (EDs) because of fears of exposure to COVID-19. OBJECTIVES: To describe the effects of the COVID-19 outbreak on admissions of surgical patients from the ED and characteristics of urgent operatio...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Conditions Favoring Increased COVID-19 Morbidity and Mortality: Their Common Denominator and Treatment.
Authors: Shevel E PMID: 33249786 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

In Vitro Fertilization Informed Consent: Revisited, Empirically.
CONCLUSIONS: C process goals are not achieved under current practices, at least as far as IVF treatment are concerned. New tools and incentives should be implemented to meet the requirements dictated by the laws regarding patient rights. PMID: 33249787 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Yield of Ileoscopy: Does Indication Matter?
Authors: Mari A, Khoury T, Mahamid M, Akram S, Kopelman Y, Abu Baker F Abstract BACKGROUND: While the routine performance of terminal ileum (TI) intubation during colonoscopy procedures is perceived to have a low yield, its utility during colonoscopies performed for specific indications have not been well studied. OBJECTIVES: To assess the diagnostic yield of an indication-based ileoscopy in real-life practice. METHODS: The authors reviewed endoscopic reports of patients who underwent colonoscopies over an 8-year period (2011-2018) and had routine ileoscopy during these procedures. Demographic data, indicat...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Re-Appraisal of Echocardiographic Assessment in Patients with Pulmonary Embolism: Prospective Blinded Long-Term Follow-Up.
Authors: Shmueli H, Steinvil A, Aviram G, Moaad S, Sharon A, Bendet A, Biner S, Shacham Y, Sherez J, Megidish R, Hasin Y, Elazar E, Letourneau-Shesaf S, Keren G, Berliner S, Topilsky Y Abstract BACKGROUND: Acute pulmonary embolism (PE) is considered to be one of the most common cardiovascular diseases with considerable mortality. Conflicting data imply possible role for echocardiography in assessing this disease. OBJECTIVES: To determine which of the echo parameters best predicts short-term and long-term mortality in patients with PE. METHODS: We prospectively enrolled 235 patients who underwent computed to...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Sex Differences in Vitamin D Deficiency and Anthropometric Measurements in School-age Children from Rural Areas in Israel.
Authors: Kassem E, Eilat-Adar S, Sindiani M, Ben-Zaken S Abstract BACKGROUND: Vitamin D is essential for skeletal health. Because peak bone mass accrual occurs during childhood and adolescence, vitamin D insufficiency during this period of life could cause adverse health outcomes. OBJECTIVES: To explore the potential sex differences in anthropometric indicators and vitamin D status among primary school-age children. METHODS: A modified food-frequency intake questionnaire was completed by 116 pre-pubertal children (52 girls, 64 boys). Body measurements were recorded and blood was drawn to assess vitamin D st...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Standardization of Burn Patients Transfer: Implementation of a Transfer Request Form to Israel's National Burn Center.
CONCLUSIONS: Implementation of a standardized transfer process will improve communication between healthcare professionals to help maintain a continuum of care. We believe that implementation of a burn transfer form in all future referrals can standardize and assure better care for burn patients, thus improving overall patient care. PMID: 33249791 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Recent Changes and Innovations in Melanoma Treatment: A Review.
Authors: Sabag N, Yakobson A, Silberstein E Abstract BACKGROUND: Malignant melanoma is one of the most extensively studied diseases in the last few decades. The outcome of these studies and the treatment changes that followed have dramatically altered the landscape of not only melanoma therapy, but all solid tumors. In this review we presented the recent advances of surgical and adjuvant management of patients with cutaneous malignant melanoma. This review focuses on stage III melanoma since this stage of disease requires surgical treatment as well as adjuvant therapy. PMID: 33249792 [PubMed - in process] (Sour...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Immune-Mediated Fetal Complete Atrioventricular Block: Can Dexamethasone Therapy Revert the Process?
We describe a case of a fetus that developed CAVB 6 days after normal sinus rhythm (NSR), who under aggressive dexamethasone therapy gradually reverted to NSR. This fetus had a previous sibling with CAVB. We assumed the immune damage to the conduction system in this small group of fetuses with a previous CAVB sibling may have occurred more quickly than usual. We therefore recommend a twice-weekly follow-up with these fetuses. PMID: 33249793 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Highlights in Autoimmunity: 2020.
Authors: Toubi E, Vadasz Z Abstract BACKGROUND: Innate and adaptive immune response dysregulations are equally involved in the induction of autoimmunity. Toll-like receptors play a leading role in the activation of innate immune cells, thus priming auto-reactive T cells. Th17 cells and related cytokines are widely involved in many immune-mediated diseases such as rheumatoid arthritis. Thus, the recent introduction of anti-IL-17 therapies should be further evaluated. Janus kinase inhibitors and Fc receptor-targeting drugs are some of the new therapeutic strategies that are being implemented when old classical therap...
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Erythema Induratum of Bazin: A Case of Chronic Unilateral Erythematous Plaques in a Lower Limb.
Authors: Santos Felisberto V, Delgado AR, Pinto H, Morais P PMID: 33249795 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Scleroderma Renal Crisis as an Early Presentation of Systemic Sclerosis.
Authors: Dolnikov K, Milo G, Assady S, Dragu R, Braun-Moscovici Y, Balbir-Gurman A PMID: 33249796 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Medical Errors According to Maimonides' Treatise on Asthma.
Authors: Garty BZ PMID: 33249797 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Difficulties in Communicating Information about Screening for Lung Cancer.
Authors: Benbassat J PMID: 33249798 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - December 1, 2020 Category: General Medicine Tags: Isr Med Assoc J Source Type: research