Twenty Years of IMAJ.
Authors: Hagay Z PMID: 30905092 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Birth of The Israel Medical Association Journal.
Authors: Blachar Y PMID: 30905093 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The 20th anniversary of IMAJ.
Authors: Shoenfeld Y, Shemer J, Keren G PMID: 30905094 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

IMAJ celebrates 20 years.
Authors: Toubi E PMID: 30905095 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

20 Years Anniversary for IMAJ - Looking Back into the Future.
Authors: Israeli E PMID: 30905096 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Glatiramer Acetate: from Bench to Bed and Back.
Authors: Arnon R, Aharoni R Abstract BACKGROUND: Glatiramer acetate (GA, Copaxone®, Copolymer1, Cop 1) is an approved drug for the treatment of relapsing-remitting multiple sclerosis (RRMS). Its efficacy in reducing the frequency of exacerbations and its safety profile establish it as a first-line therapy for MS. Evidence from the animal model experimental autoimmune encephalomyelitis (EAE) and from MS patients indicate that GA affects various levels of the innate and the adaptive immune response, inducing deviation from the pro-inflammatory to the anti-inflammatory pathways. This includes mainly the induction ...
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Helminth-Related Tuftsin-Phosphorylcholine Compound and its Interplay with Autoimmune Diseases.
Authors: Blank M, Shoenfeld Y Abstract BACKGROUND: The hygiene theory represents one of the environmental facets that modulate the risk for developing autoimmune diseases. There is a reverse correlation between the presence of helminthes and flares of autoimmune diseases, which explains the rise in incidence of certain autoimmune diseases in developed countries. The protective properties of certain helminthes are attributed to their secretory compounds which immunomodulate the host immune network in order to survive. Thus, the helminthes use an array of mechanisms. One of the major mechanisms enabling manipulation ...
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Future Evolution of Hospitals.
Authors: Zimlichman E, Afek A, Kahn CN, Kreiss Y PMID: 30905099 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Medical Humanitarian Face of Israel.
Authors: Zarka S PMID: 30905100 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Existentialism and Internal Medicine 2019: Where Do We Stand?
Authors: Elis A, Amital H PMID: 30905101 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Peripheral Medical Centers in Israel: Narrowing the Gap - A Personal Perspective.
Authors: Blum A PMID: 30905102 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Poisoning in Israel: Annual Report of the Israel Poison Information Center, 2017.
We present computerized queries and a descriptive analysis of the medical records database of the IPIC for 2017. RESULTS: A total of 39,928 poison exposure cases were recorded, reflecting increases of 226.3% and 26.7% compared with 1995 and 2012, respectively. Children
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Characteristics of Pericardial Biopsy: 100 Cases in a Single Center.
CONCLUSIONS: Our findings suggest a low diagnostic yield from pericardial biopsies, especially in malignant pericarditis. This conclusion, along with novel therapies, resulted in the infrequent use of pericardial biopsy in recent years. PMID: 30905104 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Health and Lifestyle of Adult Patients with Congenital Isolated Growth Hormone Deficiency Treated in Childhood.
CONCLUSIONS: Patients with congenital IGHD who do not receive early and regular replacement treatment are prone to lag in achieving normal height and suffer from educational and vocational handicaps. PMID: 30905105 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Incidence and Prevalence of Inflammatory Bowel Disease in the Jewish and Arab Populations of Israel.
CONCLUSIONS: Understanding the factors underlying the differences in incidence and prevalence of IBD in the Jewish and Arab populations may shed light on the genetic and environmental factors associated with these diseases. PMID: 30905106 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Differences in Stabbing-Related Injury Profiles of Men and Women.
CONCLUSIONS: There are significant differences in the injury profiles of male and female stabbing victims, which can be explained by the different circumstances of the injury event. PMID: 30905107 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Computed Tomography Angiography Findings in Pulmonary Embolism Patients Vary Following Thrombolytic Treatment.
CONCLUSIONS: The prevalence of pleural effusion (unilateral or bilateral) was higher in patients not treated with tPA. Therefore, in patients with a borderline condition, the presence of pleural effusion could support the decision not to give tPA treatment. PMID: 30905108 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Use of Unenhanced Abdominal Computed Tomography for Assessment of Acute Non-Traumatic Abdominal Pain in the Emergency Department.
CONCLUSIONS: In this study, unenhanced CT proved to be a feasible, convenient and legitimate examination for the evaluation of patients with acute non-traumatic abdominal pain presenting to the ED. PMID: 30905109 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Clinical and Radiographical Characteristics in Male and Female Adolescent Idiopathic Scoliosis Surgical Candidates.
CONCLUSIONS: In this study we were not able to demonstrate any clinical nor radiological statistical differences between male and female patients who are candidate for surgical treatment. PMID: 30905110 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Cannabis sativa as a Potential Treatment for Systemic Sclerosis.
Authors: Nogueira AR, Shoenfeld Y, Amital H PMID: 30905111 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Biotinidase Deficiency: A Treatable Neurological Inborn Error of Metabolism.
Authors: Hayek W, Dumin Y, Tal G, Zehavi Y, Sakran W, Spiegel R PMID: 30905112 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Intriguing Story of Jews' Resistance to Tuberculosis, 1850-1920.
Authors: Martini M, Mahroum N, Luigi Bragazzi N, Parodi A PMID: 30905113 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Anatomic Abnormalities in Botticelli's Artwork La Primavera.
Authors: Moldavsky M PMID: 30905114 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 25, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Inhibition of endothelial Progenitor Cells Inhibition in the first 24 hours of an Acute Ischemic Cerebrovascular Event.
Authors: Blum A, Pastukh N, Sirchan R, Blum N, Chernikoff L, Vaispapir V Abstract BACKGROUND: Endothelial progenitor cells may have a role in ongoing endothelial repair. Impaired mobilization or depletion of these cells may contribute to progression of vascular disease. Our hypothesis was that endothelial progenitor cells would be suppressed in patients with acute cerebrovascular event based on our previous study that found severe endothelial dysfunction in those patients. OBJECTIVES: To study the ability of patients with acute stroke to build colonies of endothelial progenitor cells. METHODS: We studied th...
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Case-Control Retrospective Study of Child Sexual Abuse History among Psychiatric Consultations in a General Hospital Emergency Room.
CONCLUSIONS: The characteristics of the patients with past CSA in this study are similar to community-based samples, except for a significant gender difference. To the best of our knowledge, this study is the first to investigate CSA history during hospital ED psychiatric consultations. A history of CSA should be considered during psychiatric consultations in a general hospital ED admission. PMID: 30772955 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Comparative Study of Frozen and Paraffin-Embedded Sections: Evaluation of Inflammatory Dermatoses.
CONCLUSIONS: This study suggests that FS is a valid approach for the rapid diagnosis of inflammatory dermatoses. This method is as specific as PS, although it is less sensitive. PMID: 30772956 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Unilateral Renal Agenesis Diagnosed on Early Prenatal Trans-Vaginal Scans.
CONCLUSIONS: URA is a rare finding in early trans-vaginal sonography. Associated anomalies are very common and should be sought. PMID: 30772957 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Maternal and Neonatal Complications of Pregnant Women with Mitral Stenosis.
Authors: Perelshtein Brezinov O, Simchen MJ, Ben Zekry S, Kuperstein R Abstract BACKGROUND: Rheumatic mitral stenosis (MS) is a relatively rare diagnosis in the developed countries and its treatment during pregnancy is challenging due to hemodynamic changes. With the demographic changes due to recent waves of immigration an increase in the prevalence of rheumatic heart disease is expected. OBJECTIVES: To evaluate maternal and neonatal complications in patients with mitral stenosis. METHODS: During the years 2006-2017, 22 women who underwent 31 pregnancies were followed at the Sheba Medical Center in Israel....
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Hyperchloremia and Diuresis in Children Undergoing Scoliosis Surgery: A Retrospective Cohort Study.
Authors: Friedman S, Zac L, Cattan A, Ovadia D, Lebel DE, Matot I Abstract BACKGROUND: Hyperchloremia is frequent in adult surgical patients and is associated with renal dysfunction. Studies in surgical pediatric patients are lacking. OBJECTIVES: To identify both the incidence of postoperative hyperchloremia in children undergoing surgery for idiopathic and non-idiopathic scoliosis, and the association of postoperative hyperchloremia with intraoperative fluid management and postoperative diuresis. METHODS: The records of 74 children and adolescents who underwent elective scoliosis surgery were retrospective...
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Ga-PSMA PET/CT Staging of Newly Diagnosed Intermediate- and High-Risk Prostate Cancer.
CONCLUSIONS: Ga-PSMA PET/CT shows promise as a sole whole-body imaging modality for assessing the presence of soft tissue and bone metastases in the setting of prostate cancer. PMID: 30772960 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Nationwide Survey of Intratympanic Steroids for the Management of Sudden Sensorineural Hearing Loss.
CONCLUSIONS: Our results demonstrate a variability among Israeli medical centers in many aspects of intratympanic treatment. We believe this reinforces the need for a comparative international study in order to establish a standard protocol. PMID: 30772961 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Hospitalization for Respiratory Syncytial Virus Bronchiolitis in the Palivizumab Prophylaxis Era: Need for Reconsideration of Preventive Timing and Eligibility.
CONCLUSIONS: According to the results of the present study we suggest advancing RSV prophylaxis in Israel from 1 November to mid-October. The precise palivizumab-eligible categories should be reconsidered. PMID: 30772962 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Ultrasound-Guided Botulinum Toxin Injections into the Salivary Glands for the Treatment of Drooling.
CONCLUSIONS: Ultrasound-guided botulinum toxin injections into the parotid and submandibular glands seem to be a safe and effective therapy for the treatment of drooling. Further long-term prospective studies with varying doses are warranted. PMID: 30772963 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Acute Stroke and Attenuation in Endothelial Progenitor Cells: Cause or Effect?
Authors: Vaturi M, Lev EI Abstract PMID: 30772964 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

IgG4-Related Disease and Eosinophilic Granulomatosis with Polyangiitis: Similarity or Coexistence?
Authors: Shovman O, Shoenfeld Y Abstract PMID: 30772965 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Immunoglobulin G4-Related Disease Presenting with Clinical Similarity to Churg-Strauss Syndrome.
Authors: Meridor K, Levy Y Abstract PMID: 30772966 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Bilateral Diaphragmatic Paralysis: A Rare but not to be Neglected Cause of Dyspnea.
Authors: Nogueira AR, Chatterji S, Shulimzon T, Shoenfeld Y Abstract PMID: 30772967 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Inadvertent Rapid Lipid Emulsion Administration.
Authors: Hoofien A, Mozer Y, Guz-Mark A, Hoffer V, Landau D, Shamir R Abstract PMID: 30772968 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 19, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Ultrapure Filter does not Confer Short-Term Benefits over Two Reverse Osmosis Systems in Chronic Hemodialysis Patients.
CONCLUSIONS: A double RO system to produce ultrapure water is not inferior to the use of ultrapure filters. PMID: 30685897 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Reemergence of Human Brucellosis in Israel.
CONCLUSIONS: We demonstrate the importance of analyzing incidence in the population at risk for a disease. HB is an urgent public health issue in the Arab population in Israel, mandating an immediate and long-term eradication and control program. PMID: 30685898 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Effect of Left Atrial Enlargement on Success Rates of Catheter Ablation of Atrial Fibrillation in Women.
Authors: Sabbag A, Farhadian Y, Younis A, Luria D, Gurevitz O, Nof E, Glikson M, Beinart R Abstract BACKGROUND: Catheter ablation (CA) is a well-established therapeutic option for patients with recurrent symptomatic atrial fibrillation (AF). Data on gender-related differences are limited with regard to baseline characteristics and long-term success rates of catheter ablation for AF. METHODS: We analyzed a cohort of 251 consecutive patients who underwent a first catheter ablation for AF in our institute during the period 2008 through 2015. All patients were followed by regular annual clinic visits, electrocardio...
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

COPD Exacerbator Phenotype is Inversely Associated with Current Smoking But Not with Haptoglobin Phenotype.
CONCLUSIONS: We found no relationship between haptoglobin polymorphism and frequent exacerbator status. However, frequent exacerbator status had a statistically significant association with COPD Assessment Test scores and pack-years and a negative correlation with current smoking status. PMID: 30685900 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Ascites and Gallbladder Abnormalities are Frequent Findings in Adults with Hepatitis A Virus Infection.
CONCLUSIONS: Abdominal ultrasonographic findings, such as ascites and gallbladder abnormalities, are frequently observed during acute HAV infection and are significantly associated with disease severity. PMID: 30685901 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Autoimmune Diseases in Systemic Sclerosis Patients and Their Relatives: Data from a Single Center.
Authors: Balbir-Gurman A, Shataylo V, Braun-Moscovici Y Abstract BACKGROUND: The aggregation of autoimmune diseases in relatives (AID-R) of patients with systemic sclerosis (SSc) has been reported. OBJECTIVES: To analyze the prevalence of autoimmune diseases in SSc relatives and to compare their features to those of SSc patients without AID-R (controls). METHODS: A case-control analysis compared SSc patients with AID-R to those without AID-R (25 patients) with similar disease duration. RESULTS: Among 322 patients, 25 (7.7%; 21 females, 41.4 ± 15.6 years of age, disease duration 11 ± 8.6 ye...
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Effect of Tight Glycemic Control Protocol on Hypoglycemia and Mortality in the Burn Unit: A Case-Control Study.
Authors: Wiser I, Averbuch Sagie R, Barzilai L, Haratz M, Haik J Abstract BACKGROUND: Burn injury pathophysiology is characterized by severe catabolic state and poor glycemic control. A tight glycemic control protocol using insulin for burn victims has yielded inconsistent mortality and morbidity outcomes. OBJECTIVES: To compare the effect of standard and tight glycemic control protocols on mortality and hypoglycemia events in critical care burn patients. METHODS: We conducted a case-control study of burn victims admitted to the burn intensive care unit between 2005 and 2011. Patients were assigned to eithe...
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Prevalence of Fetal Alcohol Spectrum Disorder among High-Risk Children and Adolescents in a Correctional Facility.
CONCLUSIONS: This study is the most comprehensive review of FASD among Israeli children and adolescents in a population with learning and behavior challenges. PMID: 30685904 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The Possibility of Transmitting Infections with Vaginal Ultrasound Probes: Why We Cannot Meet the Guidelines.
Authors: Ben David C, Solt I Abstract BACKGROUND: The use of ultrasound endovaginal probes is common practice in the fields of gynecology and obstetrics. The vagina serves as a host environment for many microorganisms, contributing greatly to its defensive mechanisms. It is not known whether the introduction of other microorganisms into the vaginal region are detrimental or require intensive preventative measures. Several national ultrasonography societies, as well as the Israel Ministry of Health, have addressed the proper and adequate handling of sonographic endovaginal probes, including the use of high-level dis...
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Ultrapure Dialysis Water: Is it really pure?
Authors: Tovbin D Abstract PMID: 30685906 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Human Brucellosis in Israel - The Saga Continues.
Authors: Glikman D Abstract PMID: 30685907 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Effect of Left Atrial Enlargement on Success Rates of Atrial Fibrillation Ablation in Women: A Wake-Up Call for Early Ablation.
Authors: Laish-Farkash A Abstract PMID: 30685908 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - January 29, 2019 Category: General Medicine Tags: Isr Med Assoc J Source Type: research