Otologic disease trends in Japan post-COVID-19 outbreak: A retrospective time-series analysis
CONCLUSION: Our findings indicate that COVID-19 and vaccinations had minimal discernible effects on hospitalization of patients with otologic diseases, suggesting that otologic diseases may not be significantly impacted by COVID-19 and vaccinations, which could have implications for public health policies and the allocation of healthcare resources during a pandemic. Further research and monitoring of long-term effects are warranted to validate these findings and guide healthcare decision-making.PMID:38522357 | DOI:10.1016/j.anl.2024.01.004 (Source: Herpes)
Source: Herpes - March 24, 2024 Category: Infectious Diseases Authors: Keisuke Kondo Keiji Honda Keiichi Goshima Norihiko Inoue Daisuke Shinjo Takeshi Tsutsumi Kiyohide Fushimi Source Type: research

Otologic disease trends in Japan post-COVID-19 outbreak: A retrospective time-series analysis
CONCLUSION: Our findings indicate that COVID-19 and vaccinations had minimal discernible effects on hospitalization of patients with otologic diseases, suggesting that otologic diseases may not be significantly impacted by COVID-19 and vaccinations, which could have implications for public health policies and the allocation of healthcare resources during a pandemic. Further research and monitoring of long-term effects are warranted to validate these findings and guide healthcare decision-making.PMID:38522357 | DOI:10.1016/j.anl.2024.01.004 (Source: Herpes)
Source: Herpes - March 24, 2024 Category: Infectious Diseases Authors: Keisuke Kondo Keiji Honda Keiichi Goshima Norihiko Inoue Daisuke Shinjo Takeshi Tsutsumi Kiyohide Fushimi Source Type: research

An overload of missense variants in the OTOG gene may drive a higher prevalence of familial Meniere disease in the European population
AbstractMeniere disease is a complex inner ear disorder with significant familial aggregation. A differential prevalence of familial MD (FMD) has been reported, being 9 –10% in Europeans compared to 6% in East Asians. A broad genetic heterogeneity in FMD has been described,OTOG being the most common mutated gene, with a compound heterozygous recessive inheritance. We hypothesize that anOTOG-related founder effect may explain the higher prevalence of FMD in the European population. Therefore, the present study aimed to compare the allele frequency (AF) and distribution ofOTOG rare variants across different populations. Fo...
Source: Human Genetics - March 22, 2024 Category: Genetics & Stem Cells Source Type: research

Deep Learning Model to Evaluate Sensorimotor System Ability in Patients With Dizziness for Postural Control
This study has potential to reduce balance testing time (spent on six conditions with three trials each in sensory organization test) and the size of computerized dynamic posturography (movable visual surround and force plate), and helps achieve the widespread application of the balance assessment. (Source: IEE Transactions on Neural Systems and Rehabilitation Engineering)
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 18, 2024 Category: Neuroscience Source Type: research

Surgical labyrinthectomy in the treatment of unilateral Meniere disease: a Belgian retrospective study
ConclusionsBased on our results, SL represents an efficient and safe approach to achieve vestibular deafferentation in patients with unilateral, disabling, and treatment-resistant MD, with non-functional hearing. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 15, 2024 Category: ENT & OMF Source Type: research

Sense of direction in vestibular disorders
CONCLUSIONS: SOD appears to be less affected by peripheral vestibular dysfunction than by functional and/or central diagnoses, indicating that higher level disruptions to central vestibular processing networks may impact SOD more than reductions in sensory peripheral inputs. Additionally, spatial anxiety is highly associated with orientational abilities in both patients and control subjects.PMID:38489201 | DOI:10.3233/VES-230082 (Source: Journal of Vestibular Research: Equilibrium and Orientation)
Source: Journal of Vestibular Research: Equilibrium and Orientation - March 15, 2024 Category: Neuroscience Authors: Alexander I G Moore John F Golding Anastasia Alenova Patricia Castro Adolfo M Bronstein Source Type: research

Navigating the vestibular maze: text-mining analysis of publication trends over five decades
ConclusionOur study presents a unique opportunity and point of view, exploring the evolving landscape of vestibular science publications over the past five decades. The analysis underscored the dynamic nature of the field, highlighting shifts in focus and emerging publication trends in diagnosis and treatment over time. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 15, 2024 Category: Neurology Source Type: research

Effects of Age on the Frequency Amplitude Ratio of Cervical and Ocular Vestibular Evoked Myogenic Potentials
CONCLUSIONS: Drawing from the normative FAR from this study, there is evidence that the existing MD diagnostic criteria would misidentify a considerable number of older adults. Therefore, to reduce false positives, we recommend a more stringent cVEMP and oVEMP FAR criterion in older adults.PMID:38470852 | DOI:10.1044/2024_AJA-23-00253 (Source: American Journal of Audiology)
Source: American Journal of Audiology - March 12, 2024 Category: Audiology Authors: Raghav H Jha Erin G Piker Jesus Gomez Source Type: research

Effects of Age on the Frequency Amplitude Ratio of Cervical and Ocular Vestibular Evoked Myogenic Potentials
CONCLUSIONS: Drawing from the normative FAR from this study, there is evidence that the existing MD diagnostic criteria would misidentify a considerable number of older adults. Therefore, to reduce false positives, we recommend a more stringent cVEMP and oVEMP FAR criterion in older adults.PMID:38470852 | DOI:10.1044/2024_AJA-23-00253 (Source: American Journal of Audiology)
Source: American Journal of Audiology - March 12, 2024 Category: Audiology Authors: Raghav H Jha Erin G Piker Jesus Gomez Source Type: research

A novel radiomics nomogram based on T2-sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE) images for predicting cochlear and vestibular endolymphatic hydrops in Meniere ’s disease patients
ConclusionThe novel radiomics nomograms based on T2-SPACE images were successfully constructed to predict cochlear and vestibular EH in Meniere ’s disease. The models showed a solid and superior performance and may play an important role in the EH prediction.Clinical relevance statementWe constructed a novel radiomics nomogram, which can be a very useful tool for predicting cochlear and vestibular endolymphatic hydrops in Meniere ’s disease patients.Key Points•This is the first T2-SPACE-based nomogram to predict cochlear and vestibular endolymphatic hydrops.•The nomogram is of great value to patients who are unable...
Source: European Radiology - March 8, 2024 Category: Radiology Source Type: research