Evaluation of Vestibular Functions in a Case of Vestibular Migraine With Successful Treatment With Erenumab
Ear Nose Throat J. 2023 Sep 25:1455613231202200. doi: 10.1177/01455613231202200. Online ahead of print.ABSTRACTThis is the first report of vestibular examinations before and after the successful treatment of vestibular migraine (VM), a common cause of recurrent vertigo, with calcitonin gene-related peptide (CGRP) receptor inhibitor. We evaluated a 42-year-old female with VM and concomitant probable Meniere's disease, whose headache and dizziness have improved promptly with the administration of erenumab, a CGRP receptor inhibitor. The sensorineural hearing loss in pure-tone audiometry, dysfunctions shown in vestibular exam...
Source: Ear, Nose and Throat Journal - September 25, 2023 Category: ENT & OMF Authors: Takaki Inui Fumiharu Kimura Kou Moriyama Tatsuro Kuriyama Takeo Shirai Yusuke Ayani Yuko Inaka Masako Yuki Shin-Ichi Haginomori Ryo Kawata Source Type: research

Meniere's disease: Pathogenesis, treatments, and emerging approaches for an idiopathic bioenvironmental disorder
Environ Res. 2023 Aug 28:116972. doi: 10.1016/j.envres.2023.116972. Online ahead of print.ABSTRACTMeniere's disease (MD) is a severe inner ear condition known by debilitating symptoms, including spontaneous vertigo, fluctuating and progressive hearing loss, tinnitus, and aural fullness or pressure within the affected ear. Prosper Meniere first described the origins of MD in the 1860s, but its underlying mechanisms remain largely elusive today. Nevertheless, researchers have identified a key histopathological feature called Endolymphatic Hydrops (ELH), which refers to the excessive buildup of endolymph fluid in the membrano...
Source: Environmental Research - August 30, 2023 Category: Environmental Health Authors: Masoud Mohseni-Dargah Zahra Falahati Christopher Pastras Khosro Khajeh Payal Mukherjee Amir Razmjou Sebastian Stefani Mohsen Asadnia Source Type: research

Meniere's disease: Pathogenesis, treatments, and emerging approaches for an idiopathic bioenvironmental disorder
Environ Res. 2023 Aug 28:116972. doi: 10.1016/j.envres.2023.116972. Online ahead of print.ABSTRACTMeniere's disease (MD) is a severe inner ear condition known by debilitating symptoms, including spontaneous vertigo, fluctuating and progressive hearing loss, tinnitus, and aural fullness or pressure within the affected ear. Prosper Meniere first described the origins of MD in the 1860s, but its underlying mechanisms remain largely elusive today. Nevertheless, researchers have identified a key histopathological feature called Endolymphatic Hydrops (ELH), which refers to the excessive buildup of endolymph fluid in the membrano...
Source: Environmental Research - August 30, 2023 Category: Environmental Health Authors: Masoud Mohseni-Dargah Zahra Falahati Christopher Pastras Khosro Khajeh Payal Mukherjee Amir Razmjou Sebastian Stefani Mohsen Asadnia Source Type: research

Findings of Intravenous Gadolinium Inner Ear MRI in Patients with Acute Low-Tone Sensorineural Hearing Loss
CONCLUSION: Our study showed that the cochlear hydrops ratio, especially in the apex area on the affected side, was significantly higher in patients with ALHL, indicating that EH in the cochlea contributes to the pathogenesis of ALHL.PMID:37641856 | DOI:10.21053/ceo.2023.00486 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - August 29, 2023 Category: ENT & OMF Authors: Hee Won Seo Yikyung Kim Hyung-Jin Kim Won-Ho Chung Young Sang Cho Source Type: research

Endolymphatic hydrops imaging and correlation with clinical characteristics, audiovestibular function and mental impairment in patients with Meniere ’s disease
ConclusionEndolymph-enhancing MRI was used as an important imaging method for the diagnosis of labyrinthine hydrops in Meniere ’s disease. There were certain correlation between EH and the degree of vertigo attack, hearing loss level, vestibular function, and further changes in anxiety and depression emotion. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - August 21, 2023 Category: ENT & OMF Source Type: research

Spontaneous Intracranial Hypotension: An Uncommon Cause of Postural Vestibulocochlear Symptoms
We present a case series that highlights the common vestibulocochlear symptoms and a review of the literature to increase awareness amongst otolaryngologists and highlight the path to diagnosis and management of this condition.PMID:37596853 | DOI:10.1177/01455613231194431 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - August 19, 2023 Category: ENT & OMF Authors: Samuel Sharp Peter L Silbert Scott Davies Peter Friedland Source Type: research

Spontaneous Intracranial Hypotension: An Uncommon Cause of Postural Vestibulocochlear Symptoms
We present a case series that highlights the common vestibulocochlear symptoms and a review of the literature to increase awareness amongst otolaryngologists and highlight the path to diagnosis and management of this condition.PMID:37596853 | DOI:10.1177/01455613231194431 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - August 19, 2023 Category: ENT & OMF Authors: Samuel Sharp Peter L Silbert Scott Davies Peter Friedland Source Type: research

Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission
Conclusion The current study reveals that the serum levels of Otolin-1 are not significantly different between the patients with MD in the interictal phase and the control group's healthy ones. [...] Thieme Revinter Publicações Ltda. Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, BrazilArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: International Archives of Otorhinolaryngology)
Source: International Archives of Otorhinolaryngology - August 4, 2023 Category: ENT & OMF Authors: Singh, Anup Yadav, Harsha Verma, Hitesh Sikka, Kapil Abraham, Ransi Ann Irugu, David Victor Kumar Tags: Original Research Source Type: research

Endolymphatic hydrops imaging and correlation with clinical characteristics, audiovestibular function and mental impairment in patients with Meniere ’s disease
ConclusionEndolymph-enhancing MRI was used as an important imaging method for the diagnosis of labyrinthine hydrops in Meniere ’s disease. There were certain correlation between EH and the degree of vertigo attack, hearing loss level, vestibular function, and further changes in anxiety and depression emotion. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - July 28, 2023 Category: ENT & OMF Source Type: research

Iatrogenic inner ear dehiscence associated with lateral skull base surgery: a systematic analysis of drilling injuries and their causal factors
ConclusionsInappropriate drill depth, errant lateral drilling, inadequate drill trajectory, or a combination of these led to iatrogenic IED. Image-based segmentation, individualized 3D anatomical model generation, and geometric and volumetric analyses can optimize operative plans and possibly reduce inner ear breaches from lateral skull base surgery. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - July 11, 2023 Category: Neurosurgery Source Type: research