Development of a Novel Intraoperative Neuromonitoring System Using an Accelerometer Sensor in Thyroid Surgery: A Porcine Model Study.
Conclusion: Accelerometer sensors located at the anterior neck or postcricoid area were able to identify laryngeal twitching. The stimulus intensity measured with these sensors was equivalent to that from conventional vocalis EMG. Our novel IONM system with an accelerometer sensor that checks changes in surface acceleration can be an alternative to EMG of the vocalis muscle for IONM in the future. PMID: 31195791 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - June 16, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Intratympanic Gentamicin Versus Labyrinthectomy: Inner Ear Sensitivity to Gentamicin and Impact on the Contralateral Labyrinth.
Conclusion: In our study, labyrinthectomy had an impact on the responses recorded from the contralateral ear, while IT gentamicin ablated the ipsilateral labyrinthine function without affecting the contralateral responses, possibly because of a milder, more gradual impact. We also show for the first time the order that IT gentamicin application affects the semicircular canals, with the lateral being the first to be affected. PMID: 31109159 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - May 23, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Neurocognition of Aged Patients With Chronic Tinnitus: Focus on Mild Cognitive Impairment.
Conclusion: Tinnitus severity appears to be a potential independent determinant for predicting the MCI, suggesting the underlying mechanism between chronic tinnitus and cognitive deficit. Given that MCI highly links to dementia, the evaluation of cognitive functions in aged patients with chronic tinnitus need to be considered at the initial assessment of tinnitus. PMID: 31079444 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - May 14, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Tobacco Smoking and Alcohol Consumption Are Related to Benign Parotid Tumor: A Nested Case-Control Study Using a National Health Screening Cohort.
Authors: Kim SY, Min C, Oh DJ, Choi HG Abstract Objectives: To evaluate the relationship among smoking, alcohol consumption, and obesity and benign or malignant parotid tumors in a Korean population. Methods: The Korean National Health Insurance Service-Health Screening Cohort (for ≥40-year-olds) was assessed from 2002 to 2013. In total, 336 benign parotid tumors and 46 malignant parotid tumors were matched with controls at a ratio of 1 to 4 with respect to age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia. We analyzed previous histories of smoking, alcohol consumption, and obes...
Source: Clinical and Experimental Otorhinolaryngology - May 14, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Management of Acquired Cholesteatoma Associated With Patulous Eustachian Tube and Habitual Sniffing.
Authors: Choi SW, Lee DJ, Lee SH, Oh SJ, Kong SK Abstract Objectives: To investigate the effect of surgical treatment with eustachian tube (ET) catheter insertion in patients with acquired cholesteatoma associated with patulous eustachian tube (PET) and habitual sniffing. Methods: Nine ears of nine patients (two men and seven women; age, 20 to 65 years; average, 37.9±12.0 years) of acquired cholesteatoma associated with PET and habitual sniffing who underwent cholesteatoma surgery with simultaneous additional ET catheter insertion were examined in this study. Successful treatment was defined as stoppage ...
Source: Clinical and Experimental Otorhinolaryngology - May 10, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Feasibility of Eye Tracking Assisted Vestibular Rehabilitation Strategy Using Immersive Virtual Reality.
Conclusion: Considering substantial gain may come from goal directed attention and activation of brain-network while performing VRT, our preclinical study from SEE suggests that eye tracking algorithms may work efficiently in vestibular rehabilitation using HMD. PMID: 31066247 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - May 10, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Long-term Breastfeeding in the Prevention of Allergic Rhinitis: Allergic Rhinitis Cohort Study for Kids (ARCO-Kids Study).
Authors: Han DH, Shin JM, An S, Kim JS, Kim DY, Moon S, Kim JS, Cho JS, Kim SW, Kim YH, Roh HJ, Shim WS, Rha KS, Kim SW, Lee SS, Kim DW, Cho KS, Yim HJ, Park SK, Rhee CS Abstract Objectives: There is a great deal of interest in the possibility that environmental factors may influence the risk of developing allergic rhinitis (AR) in early life. We investigated the simultaneous effects of mode of delivery and duration of breastfeeding on the development of AR in children. Methods: Data from 1,374 children participating in the Allergic Rhinitis Cohort Study for kids (ARCO-kids study) was analyzed. All subjects wer...
Source: Clinical and Experimental Otorhinolaryngology - April 18, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Response of Glucocorticoid Receptor Alpha and Histone Deacetylase 2 to Glucocorticoid Treatment Predicts the Prognosis of Sudden Sensorineural Hearing Loss.
Conclusion: A lack of GRα and HDAC2 induction following steroid treatment in GC-resistant SSNHL patients may play a fundamental mechanistic role in GC insensitivity. Response of GRα and HDAC2 to steroid treatment may, thus, predict the prognosis of hearing improvement in SSNHL patients. PMID: 30993958 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - April 18, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Abrupt Change in Electrophysiological Properties Begins From Postnatal Day 7 Before Hearing Onset in the Developing Mice Auditory Cortical Layer II/III Neurons.
Conclusion: As regular spiking cells were observed from P7 but never from P3 to P6, P7 might be regarded as an important milestone in the development of auditory cortical layer II/III neurons. This change might mainly result from the increase in Na+ current density. PMID: 30982321 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - April 17, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Perceptual and Acoustic Outcomes of Early-Stage Glottic Cancer After Laser Surgery or Radiotherapy: A Meta-Analysis.
Conclusion: Results of our meta-analysis suggested that RT might lead to superior voice quality than LS in early glottic cancer. PMID: 30959580 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - April 10, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Diagnosis of Sarcopenia in Head and Neck Computed Tomography: Cervical Muscle Mass as a Strong Indicator of Sarcopenia.
Authors: Ufuk F, Herek D, Yüksel D Abstract Objectives: Patients with head and neck cancer (HNC) have a high risk of sarcopenia, which is associated with poor prognosis. Skeletal-muscle area and index at the third lumbar (L3) vertebra level (L3MA and L3MI) are recommended for the detection of sarcopenia. However, L3 level is not included in many imaging protocols and there are no data for optimal levels and cutoffs for the diagnosis of sarcopenia in head and neck computed tomography (HNCT) scans. Our aim was to assess the relationship between cervical paravertebral muscle values and L3MI and to investigate opt...
Source: Clinical and Experimental Otorhinolaryngology - April 7, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Evolving Strategy for Surgical Management of Oral Cancer: Present and Future.
Authors: Joo YH, Koo BS PMID: 30942046 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - April 4, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Endoscopic Ear Surgery: Paradigm Shift or Subordinate Role?
Authors: Moon IJ, Kim SH PMID: 30942047 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - April 4, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Can Olfactory Tests Help to Diagnose Parkinson Disease?
Authors: Kim JK PMID: 30942048 [PubMed] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - April 4, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Antiallergic Effect of Hizikia fusiformis in an Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Authors: Zhang YL, Shin HJ, Lee JH, Lee J Abstract OBJECTIVES: The extract of Hizikia fusiformis is known to exhibit anticancer, antiatopic and antioxidant activities. We aimed to investigate the extract of H. fusiformis on allergic rhinitis inflammation in a mouse model. METHODS: The 4-week-old BALB/c mice were randomly assigned into four groups: group A, control group (n=9); group B, allergic rhinitis group (n=10); group C (n=10) received 300 mg/kg of H. fusiformis during nasal challenging period; group D (n=10) received 600 mg/kg of H. fusiformis during general sensitization period and 300 mg/kg of H. fusifo...
Source: Clinical and Experimental Otorhinolaryngology - April 4, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Nasopharyngeal Width and Its Association With Sleep-Disordered Breathing Symptoms in Children.
This study was undertaken to measure nasopharyngeal width in children undergoing adenotonsillectomy for sleep-disordered breathing and to investigate the clinical implications of this factor. Methods: This was a retrospective study with a follow-up period of 1 year, performed at a tertiary referral center. We reviewed the operative records of children who underwent adenotonsillectomy at our center for symptoms of sleepdisordered breathing, such as snoring, apnea, and mouth breathing. The nasopharyngeal width was measured immediately before adenotonsillectomy, which was performed under general anesthesia with a microsco...
Source: Clinical and Experimental Otorhinolaryngology - March 7, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Does Improved Attention Induced by Caffeine Intake Affect Olfactory Function?
Conclusion.: Caffeine may significantly improve attentional congnitive function, while not have acute effects on olfactory function. PMID: 30813710 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - March 1, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

The Effects of Air Pollutants on the Prevalence of Common Ear, Nose, and Throat Diseases in South Korea: A National Population-Based Study.
Conclusion.: We found that increased ambient concentrations of PM10 particles were clearly associated with increased the risk of chronic rhinosinusitis and septal deviation; the exposure-response relationship was definitive. PMID: 30813711 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - March 1, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Serum Vitamin D and Long-Term Outcomes of Benign Paroxysmal Positional Vertigo.
Authors: Rhim GI Abstract Objectives.: The purpose of the present study was to examine the effect of serum vitamin D concentrations on the longterm recurrence rates of benign paroxysmal positional vertigo (BPPV) patients. Methods.: The present study was conducted with patients diagnosed with BPPV from June 2014 to April 2016. Whether the patients' sex, age, types and locations of semicircular canals, diabetes, hypertension, hyperlipidemia, and vitamin D concentrations affect their recurrence rates was examined using Pearson chi-square tests, independent samples t-tests and Cox proportional hazards regression an...
Source: Clinical and Experimental Otorhinolaryngology - March 1, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Clinical Outcomes of a 14-Day In-Hospital Stay Program in Patients Undergoing Head and Neck Cancer Surgery With Free Flap Reconstruction Under the National Health Insurance System.
Conclusion.: In patients undergoing HNC surgery with free flap reconstruction as an initial treatment, a 14-day LOS could be safe in terms of comparable oncological outcomes and postoperative complications. To achieve this goal safely, careful management for T3-4 tumors and prevention of postoperative complications seem to be necessary. PMID: 30813713 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - March 1, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Guidelines for the Surgical Management of Oral Cancer: Korean Society of Thyroid-Head and Neck Surgery.
Authors: Korean Society of Thyroid-Head and Neck Surgery Guideline Task Force, Joo YH, Cho JK, Koo BS, Kwon M, Kwon SK, Kwon SY, Kim MS, Kim JK, Kim H, Nam I, Roh JL, Park YM, Park IS, Park JJ, Shin SC, Ahn SH, Won S, Ryu CH, Yoon TM, Lee G, Lee DY, Lee MC, Lee JK, Lee JC, Lim JY, Chang JW, Jang JY, Chung MK, Jung YS, Cho JG, Choi YS, Choi JS, Lee GH, Chung PS Abstract Korean Society of Thyroid-Head and Neck Surgery appointed a Task Force to provide guidance on the implementation of a surgical treatment of oral cancer. MEDLINE databases were searched for articles on subjects related to "surgical management of ...
Source: Clinical and Experimental Otorhinolaryngology - February 4, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Understanding the Biomechanical Properties of Skull Base Tissues Is Essential for the Future of Virtual Reality Endoscopic Sinus and Skull Base Surgery Simulators.
Authors: Favier V, Gallet P, Subsol G, Captier G PMID: 30700086 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - February 2, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Outcomes of Modified Canal Wall Down Mastoidectomy and Mastoid Obliteration Using Autologous Materials.
This study evaluated outcomes in patients who underwent modified canal wall down mastoidectomy (mCWDM) and mastoid obliteration using autologous materials. Methods.: Our study included 76 patients with chronic otitis media, cholesteatoma, and adhesive otitis who underwent mCWDM and mastoid obliteration using autologous materials between 2010 and 2015. Postoperative hearing airbone gap and complications were evaluated. Results.: During the average follow-up of 64 months (range, 20 to 89 months), there was no recurrent or residual cholesteatoma or chronic otitis media. No patient had a cavity problem and anatomic int...
Source: Clinical and Experimental Otorhinolaryngology - February 2, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Can Endoscopic Tympanoplasty Be a Good Alternative to Microscopic Tympanoplasty? A Systematic Review and Meta-Analysis.
Authors: Lee SY, Lee DY, Seo Y, Kim YH Abstract Although efficacies and proportions of tympanoplasty performed via endoscopic ear surgery (EES) have gradually introduced, it remains unclear whether total EES is a good alternative to microscopic ear surgery (MES). Herein, we aimed to compare therapeutic effects of EES and MES in patients receiving tympanoplasty or myringoplasty. A search of MEDLINE, PubMed, and Embase databases was conducted to compare the efficacies of EES and MES. Two investigators independently reviewed all studies and extracted data with a standardized form. We assessed risk of bias and calculat...
Source: Clinical and Experimental Otorhinolaryngology - January 26, 2019 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Characteristics of Smell Identification Test in Patients With Parkinson Disease.
Authors: Fujio H, Inokuchi G, Tatehara S, Kuroki S, Fukuda Y, Kowa H, Nibu KI Abstract Objectives: Parkinson disease (PD) is frequently associated with olfactory disorder at early stage, which is caused by deposition of Lewy bodies emerging from the olfactory bulb to higher olfactory centers. Early detection of olfactory disorder in the patients with PD may lead to the early diagnosis and treatment for this refractory disease. Methods: Visual analog scale (VAS), Jet Stream Olfactometry, and Japanese smell identification test, Open Essence (OE), were carried out on 39 patients with PD. Thirty-one patients with p...
Source: Clinical and Experimental Otorhinolaryngology - December 29, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Association Between High Neutrophil to Lymphocyte Ratio and Delayed Recovery From Bell's Palsy.
Conclusion: Higher NLR in patients with Bell's palsy was associated with longer recovery time. NLR may be prognostic of recovery time in patients with Bell's palsy. PMID: 30545211 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 16, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Development of a Novel Intraoperative Neuromonitoring System Using a Surface Pressure Sensor to Detect Muscle Movement: A Rabbit Model Study.
Conclusion: It is possible to measure the change in surface pressure by using a piezo-electric surface pressure sensor instead of EMG to detect muscle movement induced by nerve stimulation. The application of IONM using a piezo-electric surface pressure sensor during surgery is noninvasive, safe, and feasible. Measuring muscle twitching to identify the state of the nerves using the novel IONM system can be an alternative to recording of EMG responses. PMID: 30531650 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 13, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Role of Immunohistochemistry in Fine Needle Aspiration and Core Needle Biopsy of Thyroid Nodules.
Conclusion: With these data, we could conclude that IHC was more effective following CNB than following FNA. PMID: 30531651 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 13, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Decreased Aquaporin 4 and 6 mRNAs in Patients With Chronic Otitis Media With Otorrhea.
Conclusion: AQP 1, 2, 3, 4, 5, 6, 8, and 10 are involved in the development of COM. Specifically, it shows reductions in AQP 4 and 6 mRNA levels, as observed in the otorrhea group, have an effect on the clinical manifestations of COM. PMID: 30518172 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 9, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Direction-Changing and Direction-Fixed Positional Nystagmus in Patients With Vestibular Neuritis and Meniere Disease.
Conclusion: Though direction-fixed paretic PN was most common in VN and MD patients, direction-changing PN could be observed in a few patients (9%-20%) with peripheral vestibular disorders regardless of the duration from the onset of dizziness, suggesting the presence of otolith-related dizziness. PMID: 30509014 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 6, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
Authors: Demir E, Afacan NN, Celiker M, Celiker FB, ─░necikli MF, Terzi S, Dursun E Abstract Objectives: We explored whether wideband tympanometry (WBT) could be used as a screening test for superior semicircular canal dehiscence (SSCD), and obtained new WBT data (given that the test is not yet in common clinical use) on patients with SSCD. Methods: We compared the WBT data of patients clinically and radiologically diagnosed with SSCD in our hospital between 2013 and 2018 to those of healthy volunteers. We compared the resonance frequency (RF), maximum absorbance frequency (MAF), and maximum absorbance ratio (M...
Source: Clinical and Experimental Otorhinolaryngology - November 23, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Comparison Between Endoscopic Prelacrimal Medial Maxillectomy and Caldwell-Luc Approach for Benign Maxillary Sinus Tumors.
Conclusion: EPMM is the effective surgical approach for resecting benign maxillary sinus tumor compared with CLA. Although facial numbness was reported in EPMM, the duration of numbness was shorter than CLA. PMID: 30458603 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - November 23, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Does Rapid Eye Movement Sleep Aggravate Obstructive Sleep Apnea?
Conclusion: Our results demonstrated the highest AHI during REM sleep stage in total participants after control of posture. However, there were 16.2% of patients showed NREM-dominant pattern (AHINREM/AHIREM>2) and 6.8% of patients showed higher AHISWS than AHIN1N2. Therefore, each group might have a different pathophysiology of obstructive sleep apnea (OSA), and we need to consider this point when we treat the patients with OSA. PMID: 30415523 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - November 14, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Hyperbilirubinemia and Follow-up Auditory Brainstem Responses in Preterm Infants.
Conclusion: UCB is a better predictor of bilirubin-induced hearing loss than TSB in preterm infants as evaluated by serial ABR. Serial ABR testing can be a useful, noninvasive methods to evaluate early reversible bilirubin-induced hearing loss in preterm infants. PMID: 30404412 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - November 10, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Analysis of Inner Ear Anomalies in Unilateral Congenital Aural Atresia Combined With Microtia.
Authors: Park E, Lee G, Jung HH, Im GJ Abstract Objectives: The aim of this study was to analyze the incidence of inner ear anomalies in patients with unilateral congenital aural atresia (CAA) combined with microtia. Methods: We retrospectively reviewed 61 patients with unilateral CAA combined with microtia who underwent high-resolution temporal bone computed tomography (TBCT) and hearing examination. Inner ear anomalies were analyzed using TBCT and evaluated according to the Jahrsdoerfer grading system, Marx classification, and extent of inferior displacement of the mastoid tegmen. Results: Inner ear anoma...
Source: Clinical and Experimental Otorhinolaryngology - November 9, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Clinical Characteristics and Management of Saccular Cysts: A Single Institute Experience.
Conclusion: Saccular cysts can be managed endoscopically using CO2 laser, without requiring an external approach. Therefore, an endoscopic approach should be actively considered for an optimal treatment outcome. PMID: 30403838 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - November 9, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Effect of Ginkgo Biloba Extract on N-Methyl-D-Aspartic Acid Receptor Subunit 2B Expression in a Salicylate-Induced Ototoxicity Model.
Conclusion: EGb may play a role in regulating the GluN2B expression in the IC of salicylate-induced ototoxicity model. PMID: 30360042 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - October 28, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Endoplasmic Reticulum Stress Induces MUC5AC and MUC5B Expression in Human Nasal Airway Epithelial Cells.
Conclusion: These results demonstrate that ER stress plays an important role in the regulation of MUC5AC and MUC5B via the activations of XBP-1, CHOP, and ATF6 in human nasal airway epithelial cells. PMID: 30336657 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - October 20, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Virtual Reality Simulators for Endoscopic Sinus and Skull Base Surgery: The Present and Future.
Authors: Kim DH, Kim Y, Park JS, Kim SW Abstract Endoscopic sinus and skull base surgeries are minimally invasive surgical techniques that reduce postoperative symptoms and complications and enhance patients' quality of life. However, to ensure excellent surgical outcomes after such interventions, intimate familiarity with important landmarks and high-level endoscope manipulation skills are essential. Cadaver training is one possible option, but cadavers are expensive, scarce, and nonreusable and cadaver work requires specialized equipment and staff. In addition, it is difficult to mimic specific diseases using cad...
Source: Clinical and Experimental Otorhinolaryngology - October 18, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Decellularization of Trachea With Combined Techniques for Tissue-Engineered Trachea Transplantation.
Conclusion: Using combination methods may reduce exposure to chemicals, prevent the excessive influence of the matrix, and shorten the decellularization time. PMID: 30326701 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - October 18, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

The Presence of Neural Stem Cells and Changes in Stem Cell-Like Activity With Age in Mouse Spiral Ganglion Cells In Vivo and In Vitro.
Conclusion: Our findings showed the presence of self-renewing and proliferative subtypes of SGN-NSCs which might serve as a promising source for the regeneration of auditory neurons even in adult mice. PMID: 30309200 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - October 14, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Nasality Changes With Age in Normal Korean-Speaking Adults.
Conclusion: Nasalance scores for the passages containing nasal consonants decreased with age although significant increases were observed in nasal cavity volume and nasal patency with age. Therefore, the age-related decreases in nasalance scores may result from factors other than changes in the nasal cavity. PMID: 30257547 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - September 28, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Principal Clinical Factors Predicting Therapeutic Outcomes After Surgical Drainage of Postoperative Cheek Cysts: Experience From a Single Center.
Conclusion: The location and size of the cyst as well as the use of the open surgical approach were important factors in predicting the therapeutic outcome of POCC. The time point of treatment and surgical approaches should be based on the above-mentioned findings. PMID: 30257548 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - September 28, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Robotic and Endoscopic Thyroid Surgery: Evolution and Advances.
In conclusion remote access thyroidectomy is feasible and its outcomes are comparable to those of conventional transcervical thyroidectomy in highly selected patients. PMID: 30196688 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - September 11, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?
Authors: Cobanoglu HB, Vuralkan E, Arslan A, Mirasoglu B, Toklu AS Abstract Objectives: Cisplatin is an antineoplastic agent, used in the treatment of different types of malignant neoplasms. Side effects such as ototoxicity, nephrotoxicity, and bone marrow toxicity are the main limitations of its clinical use. The aim of the present study was to evaluate the possible effects of hyperbaric oxygen (HBO) therapy as a protective agent in cisplatin-induced ototoxicity in rats. Methods: A total of 30 adult Wistar rats (60 ears) were divided into five equal groups. Group 1 is a control group; group 2 is HBO therapy gr...
Source: Clinical and Experimental Otorhinolaryngology - September 8, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Prediction of Obstructive Sleep Apnea Based on Respiratory Sounds Recorded Between Sleep Onset and Sleep Offset.
Conclusion: This study showed that our binary classifier predicted patients with AHI of ≥15 with sensitivity and specificity of>80% by using respiratory sounds during sleep. Since our prediction model included all sleep stage data, algorithms based on respiratory sounds may have a high value for prescreening OSA with mobile devices. PMID: 30189718 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - September 8, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Comparison of the Clinical Results of Attic Cholesteatoma Treatment: Endoscopic Versus Microscopic Ear Surgery.
Conclusion: The endoscopic approach for the management of attic cholesteatoma is as useful as the microscopic approach. PMID: 30165729 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - September 1, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Auditory Deficits in Patients With Mild and Moderate Obstructive Sleep Apnea Syndrome: A Speech Syllable Evoked Auditory Brainstem Response Study.
Authors: Fu Q, Wang T, Liang Y, Lin Y, Zhao X, Wan J, Fan S Abstract Objectives.: The energy consumption process of cochlea and neural signal transduction along the auditory pathway are highly dependent on blood oxygen supply. At present, it is under debate on whether the obstructive sleep apnea syndrome (OSAS) would affect the auditory function since the patients suffer from low oxygen saturation. Moreover, it is difficult to detect the functional state of auditory in less severe stage of OSAS. Recently, speech-evoked auditory brainstem response (speech-ABR) has been reported to be a new electrophysiological tool ...
Source: Clinical and Experimental Otorhinolaryngology - August 25, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Body Surface Area Is Not a Reliable Predictor of Tracheal Tube Size in Children.
Conclusion: The Cole formula, BSA, and ultrasonography had similar estimation rates in patients aged 24≤ to ≤96 months. BSA had a correct estimation rate of 40.2% and may not be reliable in clinical practice to predict uncuffedETT-size. PMID: 30139232 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - August 25, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research

Two Compound Heterozygous Were Identified in SLC26A4 Gene in Two Chinese Families With Enlarged Vestibular Aqueduct.
Conclusion: In summary, this study revealed two compound heterozygous mutations (c.1174A>T/c.1181delTCT; c.919- 2A>G/c.1023insC) in Pendrin protein, which might account for the deafness of the two probands clinically diagnosed with EVA. Thus this study contributes to improve understanding of the causes of hearing loss associated with EVA and develop a more scientific screening strategy for deafness. PMID: 30086623 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - August 9, 2018 Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research