Early postoperative benefit in receptive and expressive language development of cochlear implantation under 9 months of age in comparison to those implanted at later ages
CONCLUSION: CI before 9 months of age significantly enhances receptive language development than CI implanted later, maintaining its effect at least up to the age 2. This study supports the consideration of earlier CI, beyond pediatric FDA labeling criteria (>9 months), in children with profound deafness, who have a clear deafness etiology and language development delays (<1 percentile).PMID:38326998 | DOI:10.21053/ceo.2024.00011 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - February 8, 2024 Category: ENT & OMF Authors: Seung Jae Lee Heonjeong Oh Kyu Ha Shin Sung-Min Park Yun Kyeong Kim Do Hyun Jung Jiyeon Yang Yejun Chun Min Young Kim Jin Hee Han Ju Ang Kim Ngoc-Trinh Tran Bong Jik Kim Byung Yoon Choi Source Type: research

Positive airway pressure therapy compliance in patients with comorbid insomnia and sleep apnea (COMISA)
CONCLUSION: This study demonstrated no significant disparity in PAP compliance between the COMISA and control groups at either 3 or 9 months. Furthermore, insomnia clinic visits did not significantly impact PAP compliance in COMISA patients during the 3- and 9-month intervals.PMID:38291866 | DOI:10.21053/ceo.2023.00017 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 31, 2024 Category: ENT & OMF Authors: Mi Rye Bae Young-Ha Lee Sei Won Lee Seokhoon Chung Yoo-Sam Chung Source Type: research

Electrically Evoked Auditory Brainstem Response Using Extracochlear Stimulation at Different Cochlear Sites: A Comparison With Intracochlear Stimulation
CONCLUSION: Our Results indicated that eEABR slopes showed significant spatial correlations to the functionality of the auditory nerve. Therefore, eEABR tests at various cochlear positions possibly can be used for estimating the extent of excitable SGNs in cochlear implant candidates prior to implantation.PMID:38273767 | DOI:10.21053/ceo.2023.00034 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 26, 2024 Category: ENT & OMF Authors: Woongsang Sunwoo Woonhoe Goo Seung-Ha Oh Source Type: research

Hair Cell Regeneration: From Animals to Humans
Clin Exp Otorhinolaryngol. 2024 Jan 19. doi: 10.21053/ceo.2023.01382. Online ahead of print.ABSTRACTCochlear hair cells are critical in converting sound into electrical signals that are relayed via the spiral ganglion neurons to the central auditory pathway. Hair cells are vulnerable to damage caused by excessive noise, aging, and ototoxic agents. Non-mammals can regenerate lost hair cells by mitotic regeneration and direct transdifferentiation of surrounding supporting cells. However, in mature mammals, damaged hair cells are not replaced, resulting in permanent hearing loss. Recent studies have uncovered mechanisms by wh...
Source: Clinical and Experimental Otorhinolaryngology - January 25, 2024 Category: ENT & OMF Authors: Sung-Won Choi Julia Abitbol Alan Cheng Source Type: research

Development and validation of a pathomics model for predicting CXCL8 expression and prognosis with machine learning in head and neck cancer
CONCLUSION: The pathomics model reflected by CXCL8 mRNA expression is an effective tool for predicting the prognosis in HNSCC patients and can assist clinical decisiondecision-making. High CXCL8 expression may contribute to decreased DNA damage and associate with the pro pro-inflammatory microenvironment, providing a potential target for tumor therapy.PMID:38246983 | DOI:10.21053/ceo.2023.00026 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 21, 2024 Category: ENT & OMF Authors: Weihua Wang Suyu Ruan Yuhang Xie Shengjian Fang Junxian Yang Xueyan Li Yu Zhang Source Type: research

Downregulation of TET2 contributes to nasal polypogenesis through HIF1 α-mediated epithelial-to-mesenchymal transition
CONCLUSION: TET2 was negatively correlated with HIF1α and EMT in vivo. Moreover, TET2 was down-regulated by HIF1α, resulting in EMT in CoCl2-hypoxia hNECs via regulation of oxidative stress in vitro. Hence, TET2 might provide a new therapeutic approach for CRSwNP.PMID:38228132 | DOI:10.21053/ceo.2023.01340 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 16, 2024 Category: ENT & OMF Authors: Kunyu Liu Yu Xu Source Type: research

Changes in Revision Cochlear Implantation and Device Failure Profiles
CONCLUSION: Although the overall survival of CI appears to be stable, device failure is still the most common cause of RCIs. In addition, the pattern of revision has changed, such as flap retention issue and electrode tip fold-over, particularly for the recently released implant models. Due to the clinical significance of device failure and re-operation, clinicians should be aware of and respond to these changes.PMID:38228133 | DOI:10.21053/ceo.2023.00010 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 16, 2024 Category: ENT & OMF Authors: Bokhyun Song Subi Oh Doyun Kim Young Sang Cho Il Joon Moon Source Type: research

Comparison of partial and superficial or total parotidectomies for superficial T1-2 primary parotid cancers
CONCLUSION: The conservative surgical approach of partial parotidectomy can yield oncologic outcomes comparable to superficial or total parotidectomies under careful patient selection in T1-2 parotid cancers.PMID:38228134 | DOI:10.21053/ceo.2023.00014 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - January 16, 2024 Category: ENT & OMF Authors: Seung Hoon Han Jihae Lee Jeong Wook Kang Heejin Kim Dong Jin Lee Jin Hwan Kim Il Seok Park Source Type: research

Analysis of differences in nasal shapes and degree of changes with pairing analysis
CONCLUSION: Our findings indicate that the aging nose exhibits a relatively longer nasal length with inferior angulation of the nasal tip, with an increase in the nasofrontal angle, profile nasal length, and nasal bridge height, along with a decrease in the nasofacial angle. Most of the degree of nasal morphologic changes demonstrated no differences by specific age period.PMID:38062715 | DOI:10.21053/ceo.2023.01137 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 8, 2023 Category: ENT & OMF Authors: Younghac Kim Joo Hyun Park Minhae Park Eunkyu Lee Sang Duk Hong Yong Gi Jung Gwanghui Ryu Hyo Yeol Kim Source Type: research

The Effects of Music-Based Auditory Training on Hearing-Impaired Elderly with Mild Cognitive Impairment
CONCLUSION: : The music-based auditory training produced a positive effect in terms of a meaningful change in auditory function and also partial cognitive ability in the elderly patients with hearing loss and MCI. We expect that the music-based method will be used for auditory training of the elderly in clinics because of interesting and easy to follow.PMID:38062716 | DOI:10.21053/ceo.2023.00815 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 8, 2023 Category: ENT & OMF Authors: Sihun Park Kyoung Ho Park Woojae Han Source Type: research

Analysis of differences in nasal shapes and degree of changes with pairing analysis
CONCLUSION: Our findings indicate that the aging nose exhibits a relatively longer nasal length with inferior angulation of the nasal tip, with an increase in the nasofrontal angle, profile nasal length, and nasal bridge height, along with a decrease in the nasofacial angle. Most of the degree of nasal morphologic changes demonstrated no differences by specific age period.PMID:38062715 | DOI:10.21053/ceo.2023.01137 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 8, 2023 Category: ENT & OMF Authors: Younghac Kim Joo Hyun Park Minhae Park Eunkyu Lee Sang Duk Hong Yong Gi Jung Gwanghui Ryu Hyo Yeol Kim Source Type: research

The Effects of Music-Based Auditory Training on Hearing-Impaired Elderly with Mild Cognitive Impairment
CONCLUSION: : The music-based auditory training produced a positive effect in terms of a meaningful change in auditory function and also partial cognitive ability in the elderly patients with hearing loss and MCI. We expect that the music-based method will be used for auditory training of the elderly in clinics because of interesting and easy to follow.PMID:38062716 | DOI:10.21053/ceo.2023.00815 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 8, 2023 Category: ENT & OMF Authors: Sihun Park Kyoung Ho Park Woojae Han Source Type: research

Analysis of differences in nasal shapes and degree of changes with pairing analysis
CONCLUSION: Our findings indicate that the aging nose exhibits a relatively longer nasal length with inferior angulation of the nasal tip, with an increase in the nasofrontal angle, profile nasal length, and nasal bridge height, along with a decrease in the nasofacial angle. Most of the degree of nasal morphologic changes demonstrated no differences by specific age period.PMID:38062715 | DOI:10.21053/ceo.2023.01137 (Source: Clinical and Experimental Otorhinolaryngology)
Source: Clinical and Experimental Otorhinolaryngology - December 8, 2023 Category: ENT & OMF Authors: Younghac Kim Joo Hyun Park Minhae Park Eunkyu Lee Sang Duk Hong Yong Gi Jung Gwanghui Ryu Hyo Yeol Kim Source Type: research