Vestibular Drop Attacks and Meniere's Disease as Results of Otolithic Membrane Damage-A Numerical Model
J Assoc Res Otolaryngol. 2022 Dec 14. doi: 10.1007/s10162-022-00880-0. Online ahead of print.NO ABSTRACTPMID:36517730 | DOI:10.1007/s10162-022-00880-0 (Source: Cell Research)
Source: Cell Research - December 14, 2022 Category: Cytology Authors: Nicholas Senofsky Justin Faber Dolores Bozovic Source Type: research
Vestibular Drop Attacks and Meniere ’s Disease as Results of Otolithic Membrane Damage—A Numerical Model
The objective of this study is to determine if otolithic membrane damage alone is sufficient to induce spurious vestibular signals, thus potentially eliciting VDAs and the vestibular dysfunction seen in patients with MD. We use a previously developed numerical model to describe the nonlinear dynamics of an array of active, elastically coupled hair cells. We then reduce the coupling strength of a selected region of the membrane to model the effects of tissue damage. As we reduce the coupling strength, we ob serve large and abrupt spikes in hair bundle position. As bundle displacements from the equilibrium position have been...
Source: JARO - Journal of the Association for Research in Otolaryngology - December 14, 2022 Category: ENT & OMF Source Type: research
Assessing the usefulness of inner ear contrast-enhanced magnetic resonance imaging and pure-tone audiometry in estimating the prognostic value of hearing improvement in patients with definite Meniere ’s disease
ConclusionsEstimating hearing improvement in patients with DMD using IEC –MRI was not possible. However, PTA showed better hearing prognosis in LTL than in LMTL. Therefore, estimating hearing improvement using PTA was possible at disease attack. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - December 10, 2022 Category: ENT & OMF Source Type: research
Long-term efficacy of dexamethasone treatment via tympanic antrum catheterization for intractable Meniere's disease
ConclusionDexamethasone treatment via TAC can effectively control vertigo attacks and improve related symptoms of intractable MD patients, providing valuable new insights into the treatment of MD. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - December 2, 2022 Category: Neurology Source Type: research
Direction-changing spontaneous nystagmus in patients with dizziness
ConclusionsAlthough the periodicity of DCSN could not be determined because of insufficiently long observation times, it was observed in various central and peripheral vestibulopathies. Careful examination of spontaneous nystagmus over a sufficient period may ensure the detection of DCSN when evaluating dizziness. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - December 1, 2022 Category: ENT & OMF Source Type: research
