Advancing Holmium Laser Enucleation of the Prostate Outcomes Reporting: An Assessment of Patient-Reported Outcomes in the Literature
Holmium laser enucleation of the prostate (HoLEP) is a size independent option for benign prostatic hyperplasia (BPH) surgical management. Since lower urinary tract symptoms (LUTS) are a quality-of-life issue, studies should prioritize patient reported outcomes (PROs). This HoLEP review assesses PROs inclusion in the top 20 cited HoLEP studies and defines their limitations. PROs were categorized by domain: LUTS, incontinence, sexual function, pain, hematuria, and patient satisfaction. On review, no top cited study included all PRO domains. (Source: Urology)
Source: Urology - March 3, 2024 Category: Urology & Nephrology Authors: Laena Hines, Kaela Mali, Timothy Campbell, Rajat Jain, Scott O Quarrier Source Type: research
Leuconostoc mesenteroides and Liquorilactobacillus mali strains, isolated from Algerian food products, are producers of the postbiotic compounds dextran, oligosaccharides and mannitol
AbstractSix lactic acid bacteria (LAB) isolated from Algerian sheep ’s milk, traditional butter, date palm sap and barley, which produce dextran, mannitol, oligosaccharides and vitamin B2 have been characterized. They were identified asLeuconostoc mesenteroides (A4X, Z36P, B12 and O9) andLiquorilactobacillus mali (BR201 and FR123). Their exopolysaccharides synthesized from sucrose by dextransucrase (Dsr) were characterized as dextrans with (1,6)-d-glucopyranose units in the main backbone and branched at positionsO-4,O-2 and/orO-3, withd-glucopyranose units in the side chain. A4X was the best dextran producer (4.5 g/L),...
Source: World Journal of Microbiology and Biotechnology - February 29, 2024 Category: Microbiology Source Type: research
Characteristics of Hospitalized COVID-19 Patients at Admission and Factors Associated with Clinical Severity in Low- and Middle-Income Countries: An Observational Study
The objective of this observational, prospective, hospital-based multicentric study was to describe clinical features and outcomes of laboratory-confirmed COVID-19 patients hospitalized in each of the participating centers in Bangladesh, Guinea, Ivory Coast, Lebanon, Madagascar, and Mali during the first year of the pandemic (March 5, 2020 to May 4, 2021). The study outcome was the clinical severity of COVID-19, defined as hospitalization in intensive care unit or death. Multivariate logistic regression models were performed to identify independent variables associated with disease severity. Overall, 1,096 patients were in...
Source: The American Journal of Tropical Medicine and Hygiene - February 27, 2024 Category: Tropical Medicine Authors: Marianne Abifadel Kaousar Ahmmed Sayera Banu Ibrahima Camara Fahmida Chowdhury Daouda Coulibaly Georges Dabar C édric Dananché Rachel Daw Zakiul Hassan Magali Herv é Ariful Islam Florence Komurian-Pradel Jean-Pierre Kouam é Bourema Kouriba Josette Naj Source Type: research
Characteristics of Hospitalized COVID-19 Patients at Admission and Factors Associated with Clinical Severity in Low- and Middle-Income Countries: An Observational Study
The objective of this observational, prospective, hospital-based multicentric study was to describe clinical features and outcomes of laboratory-confirmed COVID-19 patients hospitalized in each of the participating centers in Bangladesh, Guinea, Ivory Coast, Lebanon, Madagascar, and Mali during the first year of the pandemic (March 5, 2020 to May 4, 2021). The study outcome was the clinical severity of COVID-19, defined as hospitalization in intensive care unit or death. Multivariate logistic regression models were performed to identify independent variables associated with disease severity. Overall, 1,096 patients were in...
Source: Am J Trop Med Hyg - February 27, 2024 Category: Infectious Diseases Authors: Marianne Abifadel Kaousar Ahmmed Sayera Banu Ibrahima Camara Fahmida Chowdhury Daouda Coulibaly Georges Dabar C édric Dananché Rachel Daw Zakiul Hassan Magali Herv é Ariful Islam Florence Komurian-Pradel Jean-Pierre Kouam é Bourema Kouriba Josette Naj Source Type: research
Characteristics of Hospitalized COVID-19 Patients at Admission and Factors Associated with Clinical Severity in Low- and Middle-Income Countries: An Observational Study
The objective of this observational, prospective, hospital-based multicentric study was to describe clinical features and outcomes of laboratory-confirmed COVID-19 patients hospitalized in each of the participating centers in Bangladesh, Guinea, Ivory Coast, Lebanon, Madagascar, and Mali during the first year of the pandemic (March 5, 2020 to May 4, 2021). The study outcome was the clinical severity of COVID-19, defined as hospitalization in intensive care unit or death. Multivariate logistic regression models were performed to identify independent variables associated with disease severity. Overall, 1,096 patients were in...
Source: The American Journal of Tropical Medicine and Hygiene - February 27, 2024 Category: Tropical Medicine Authors: Marianne Abifadel Kaousar Ahmmed Sayera Banu Ibrahima Camara Fahmida Chowdhury Daouda Coulibaly Georges Dabar C édric Dananché Rachel Daw Zakiul Hassan Magali Herv é Ariful Islam Florence Komurian-Pradel Jean-Pierre Kouam é Bourema Kouriba Josette Naj Source Type: research
Characteristics of Hospitalized COVID-19 Patients at Admission and Factors Associated with Clinical Severity in Low- and Middle-Income Countries: An Observational Study
The objective of this observational, prospective, hospital-based multicentric study was to describe clinical features and outcomes of laboratory-confirmed COVID-19 patients hospitalized in each of the participating centers in Bangladesh, Guinea, Ivory Coast, Lebanon, Madagascar, and Mali during the first year of the pandemic (March 5, 2020 to May 4, 2021). The study outcome was the clinical severity of COVID-19, defined as hospitalization in intensive care unit or death. Multivariate logistic regression models were performed to identify independent variables associated with disease severity. Overall, 1,096 patients were in...
Source: Am J Trop Med Hyg - February 27, 2024 Category: Infectious Diseases Authors: Marianne Abifadel Kaousar Ahmmed Sayera Banu Ibrahima Camara Fahmida Chowdhury Daouda Coulibaly Georges Dabar C édric Dananché Rachel Daw Zakiul Hassan Magali Herv é Ariful Islam Florence Komurian-Pradel Jean-Pierre Kouam é Bourema Kouriba Josette Naj Source Type: research
Characteristics of Hospitalized COVID-19 Patients at Admission and Factors Associated with Clinical Severity in Low- and Middle-Income Countries: An Observational Study
The objective of this observational, prospective, hospital-based multicentric study was to describe clinical features and outcomes of laboratory-confirmed COVID-19 patients hospitalized in each of the participating centers in Bangladesh, Guinea, Ivory Coast, Lebanon, Madagascar, and Mali during the first year of the pandemic (March 5, 2020 to May 4, 2021). The study outcome was the clinical severity of COVID-19, defined as hospitalization in intensive care unit or death. Multivariate logistic regression models were performed to identify independent variables associated with disease severity. Overall, 1,096 patients were in...
Source: The American Journal of Tropical Medicine and Hygiene - February 27, 2024 Category: Tropical Medicine Authors: Marianne Abifadel Kaousar Ahmmed Sayera Banu Ibrahima Camara Fahmida Chowdhury Daouda Coulibaly Georges Dabar C édric Dananché Rachel Daw Zakiul Hassan Magali Herv é Ariful Islam Florence Komurian-Pradel Jean-Pierre Kouam é Bourema Kouriba Josette Naj Source Type: research
A novel de novo variant in the RUNX2 gene causes cleidocranial dysplasia in a Malian girl
We report the first case in Mali, caused by a novel de novo variant in the RUNX2 gene.AbstractCleidocranial dysplasia (CCD) is a rare autosomal dominant skeletal dysplasia characterized by an aplastic/hypoplastic clavicles, patent sutures and fontanels, dental abnormalities and a variety of other skeletal changes. We report a novel de novo variant in theRUNX2 gene causing a severe phenotype of CCD in a Malian girl. (Source: Clinical Case Reports)
Source: Clinical Case Reports - February 27, 2024 Category: General Medicine Authors: Lassana Ciss é,
Abdoulaye Yalcouyé,
Kadidia Oumar Touré,
Youlouza Coulibaly,
Alassane Baneye Maiga,
Salia Bamba,
Dramane Diallo,
Salimata Diarra,
Abdoulaye Taméga,
Oumou Traoré,
Mahamadou Kotioumbé,
Moussa Aly Sangaré,
Hamidou Oumar Ba, Tags: CASE REPORT Source Type: research
Viruses, Vol. 16, Pages 355: Identification of Mycoviruses in the Pathogens of Fragrant Pear Valsa Canker from Xinjiang in China
In this study, 199 isolates were obtained from diseased branches of fragrant pear in the main production areas of Xinjiang. Among them, 134 belonged to Valsa spp., identified using morphological and molecular biological techniques, in which V. mali was the dominant species. The mycoviruses in Valsa spp. were further identified using metatranscriptomic sequencing and RT-PCR. The results revealed that a total of seven mycoviruses were identified, belonging to Botourmiaviridae, Endornaviridae, Fusariviridae, Hypoviridae, Mitoviridae, and Narnaviridae, among which Phomopsis longicolla hypovirus (PlHV) was dominant in all the s...
Source: Viruses - February 25, 2024 Category: Virology Authors: Chenguang Zhang Xiaoya Zheng Zhanjiang Tie Hui Xi Mai Shi Yanjun Ma Wenbin Chen Yingjie Mi Rui Yang Sifeng Zhao Xuekun Zhang Tags: Article Source Type: research
SARS-CoV-2 seroprevalence in vaccine-na ïve participants from the Democratic Republic of Congo, Guinea, Liberia, and Mali
In the four years since COVID-19 was declared a global pandemic on March 11, 2020, more than 760 million cases have been reported worldwide leading to a death toll of almost 7 million people [1]. During the first year of the pandemic, while high rates of SARS-CoV-2 infections were reported globally, initial reports suggested that infection rates were significantly lower in sub-Saharan Africa than in other parts of the world [2,3]. Subsequent studies revealed that although seroprevalence was rapidly increasing in sub-Saharan African countries during the start of the pandemic, it was estimated that less than 1% of infections...
Source: International Journal of Infectious Diseases - February 25, 2024 Category: Infectious Diseases Authors: Laverdure Sylvain, Kazadi Donatien, Kone Kadidia, Callier Viviane, Dabitao Djeneba, Dennis Dehkontee, Haidara Mory Cherif, Hunsberger Sally, Mbaya Olivier Tshiani, Ridzon Renee, Sereti Irini, Shaw-Saliba Katy, the InVITE Study Team Source Type: research
A rare case of thyrotoxic periodic paralysis revealing Graves' disease in a young Malian
AbstractSporadic thyrotoxic periodic paralysis (TPP) is a rare muscle disorder that manifests with abrupt muscle weakness and hypokalemia associated with hyperthyroidism. It is mostly reported in the Asian population, and rare in Caucasians. Only few cases have been reported in people with black ancestry. Here, we report a rare case of thyrotoxic periodic paralysis revealing Graves' disease in a young Malian. A 17-year-old man was admitted in the Neurology clinic with rapid proximal tetraplegia that started after strenuous physical activities at the school. Clinical examination confirmed the proximal weakness. In addition,...
Source: Clinical Case Reports - February 23, 2024 Category: General Medicine Authors: Mohamed Emile Demb élé,
Abdoulaye Yalcouyé,
Mamadou Cissoko,
Lassana Cissé,
Cheick Oumar Guinto,
Guida Landouré Tags: CASE REPORT Source Type: research
Pro: Methadone should be used as a part of Enhanced Recovery after Cardiac Surgery (ERACS) protocol
Methadone is a highly effective synthetic opioid (FDA approved in 1947) used primarily in opioid use disorder treatment but has been studied and used for acute perioperative pain treatment. Its duration of action is highly dependent on dose and frequency. Methadone has a short speed of onset of 6-8 minutes and redistribution half-life of approximately 6 minutes but with increasing dosage (>= 20 mg) its elimination half-life is extended to approximately 30 hours (range 8 ≥ 59 hours).1,2 Methadone's mechanism of action involves effects at several sites central in nociception including mu-opioid receptor, N-methyl-D-Asparta...
Source: Journal of Cardiothoracic and Vascular Anesthesia - February 21, 2024 Category: Anesthesiology Authors: Shelby Garcia, Mitali Mali, Ashanpreet Grewal Tags: Pro and Con Source Type: research
Molecules, Vol. 29, Pages 947: Chemical Composition of Piper nigrum L. Cultivar Guajarina Essential Oils and Their Biological Activity
veira
Eloisa Helena de Aguiar Andrade
The essential oils and aroma derived from the leaves (L), stems (St), and spikes (s) of Piper nigrum L. cv. Guajarina were extracted; the essential oils were extracted using hydrodistillation (HD), and steam distillation (SD), and the aroma was obtained by simultaneous distillation and extraction (SDE). Chemical constituents were identified and quantified using GC/MS and GC-FID. Preliminary biological activity was assessed by determining the toxicity against Artemia salina Leach larvae, calculating mortality rates, and determining lethal concentration values (LC50). The predomina...
Source: Molecules - February 21, 2024 Category: Chemistry Authors: Bruna de Souza Feitosa Oberdan Oliveira Ferreira Celeste de Jesus Pereira Franco Himani Karakoti Ravendra Kumar Marcia Moraes Cascaes Rahul D. Jawarkar Suraj N. Mali Jorddy Neves Cruz Ilmarina Campos de Menezes Mozaniel Santana de Oliveira Eloisa Helena d Tags: Article Source Type: research
Pro: Methadone Should Be Used as a Part of Enhanced Recovery After Cardiac Surgery Protocol
METHADONE IS A HIGHLY effective synthetic opioid (Food and Drug Administration-approved in 1947) used primarily in opioid use disorder treatment, but has been studied and used for acute perioperative pain treatment. Its duration of action is highly dependent on dose and frequency. Methadone has a short speed of onset of 6-to-8 minutes, and a redistribution half-life of approximately 6 minutes, but with increasing dosage ( ≥20 mg), its elimination half-life is extended to approximately 30 hours (range 8 ≥ 59 hours). (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - February 21, 2024 Category: Anesthesiology Authors: Shelby Garcia, Mitali Mali, Ashanpreet Grewal Tags: Pro and Con Source Type: research
User requirements for non-invasive and minimally invasive glucose self-monitoring devices in low-income and middle-income countries: a qualitative study in Kyrgyzstan, Mali, Peru and Tanzania
Conclusions
Ease-of-use and affordability were consistently prioritised, with broad functionality required for alarms, measurements and attachment possibilities. Perspectives of PLWD are crucial in developing a target product profile to inform characteristics of NI-MI-GMDs in LMICs. Stakeholders must consider these requirements to guide development and selection of NI-MI-GMDs at country level, so that devices are fit for purpose and encourage frequent glucose monitoring among PLWD in these settings. (Source: BMJ Open)
Source: BMJ Open - February 17, 2024 Category: General Medicine Authors: Safary, E., Beran, D., Vetter, B., Lepeska, M., Abdraimova, A., Dunganova, A., Besancon, S., Lazo-Porras, M., Portocarrero Mazanett, J., Perez-Leon, S., Maixenchs, M., Nchimbi, H., Ramaiya, K., Munishi, C., Martinez-Perez, G. Z. Tags: Open access, Diabetes and Endocrinology Source Type: research
