Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: The American Journal of Tropical Medicine and Hygiene - March 26, 2024 Category: Tropical Medicine Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: Am J Trop Med Hyg - March 26, 2024 Category: Infectious Diseases Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: The American Journal of Tropical Medicine and Hygiene - March 26, 2024 Category: Tropical Medicine Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: Am J Trop Med Hyg - March 26, 2024 Category: Infectious Diseases Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: The American Journal of Tropical Medicine and Hygiene - March 26, 2024 Category: Tropical Medicine Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: Am J Trop Med Hyg - March 26, 2024 Category: Infectious Diseases Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: The American Journal of Tropical Medicine and Hygiene - March 26, 2024 Category: Tropical Medicine Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: Am J Trop Med Hyg - March 26, 2024 Category: Infectious Diseases Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: The American Journal of Tropical Medicine and Hygiene - March 26, 2024 Category: Tropical Medicine Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
We examined hematological and clinical chemistry parameters in healthy residents at two rural vaccine trial sites: Bancoumana and Doneguebougou in Mali, West Africa. During screening of clinical studies in 2018 and 2019, peripheral blood samples from 1,192 apparently healthy individuals age 6 months to 82 years were analyzed at a laboratory accredited by the College of American Pathologists for a complete blood count, and creatinine and/or alanine aminotransferase levels. Based on manufacturers' reference range values, which are currently used in Malian clinical laboratories, abnormal values were common in this healthy pop...
Source: Am J Trop Med Hyg - March 26, 2024 Category: Infectious Diseases Authors: M'Bouye Doucoure Amatigue Zeguime Amadou Niangaly Merepen A Guindo Justin Y A Doritchamou Mahamadoun H Assadou Abdoulaye Katile Moussa B Kanoute Sidiki Perou Adama Ouattara Sintry Sanogo Boucary Ouologuem Souleymane Traore Bakary Dao Drissa Dembele Mamady Source Type: research

Updates in the Management of Uveal Melanoma
Cancer J. 2024 Mar-Apr 01;30(2):92-101. doi: 10.1097/PPO.0000000000000708.ABSTRACTUveal melanoma (UM), arising from intraocular melanocytes, poses a complex clinical challenge with a substantial risk of distant metastasis, often to the liver. Molecular profiling, encompassing genetic, cytogenetic, gene expression, and immunological subsets, plays a pivotal role in determining prognoses. The evolving landscape includes promising systemic treatments, such as tebentafusp, a novel immune-modulating bispecific fusion protein, and targeted therapies. Combined regional and systemic approaches, including immune checkpoint inhibito...
Source: Cancer Journal - March 25, 2024 Category: Cancer & Oncology Authors: Mali Barbi Richard D Carvajal Craig E Devoe Source Type: research

Updates in the Management of Uveal Melanoma
Cancer J. 2024 Mar-Apr 01;30(2):92-101. doi: 10.1097/PPO.0000000000000708.ABSTRACTUveal melanoma (UM), arising from intraocular melanocytes, poses a complex clinical challenge with a substantial risk of distant metastasis, often to the liver. Molecular profiling, encompassing genetic, cytogenetic, gene expression, and immunological subsets, plays a pivotal role in determining prognoses. The evolving landscape includes promising systemic treatments, such as tebentafusp, a novel immune-modulating bispecific fusion protein, and targeted therapies. Combined regional and systemic approaches, including immune checkpoint inhibito...
Source: Cancer Journal - March 25, 2024 Category: Cancer & Oncology Authors: Mali Barbi Richard D Carvajal Craig E Devoe Source Type: research

Updates in the Management of Uveal Melanoma
Cancer J. 2024 Mar-Apr 01;30(2):92-101. doi: 10.1097/PPO.0000000000000708.ABSTRACTUveal melanoma (UM), arising from intraocular melanocytes, poses a complex clinical challenge with a substantial risk of distant metastasis, often to the liver. Molecular profiling, encompassing genetic, cytogenetic, gene expression, and immunological subsets, plays a pivotal role in determining prognoses. The evolving landscape includes promising systemic treatments, such as tebentafusp, a novel immune-modulating bispecific fusion protein, and targeted therapies. Combined regional and systemic approaches, including immune checkpoint inhibito...
Source: Cancer Journal - March 25, 2024 Category: Cancer & Oncology Authors: Mali Barbi Richard D Carvajal Craig E Devoe Source Type: research

Updates in the Management of Uveal Melanoma
Cancer J. 2024 Mar-Apr 01;30(2):92-101. doi: 10.1097/PPO.0000000000000708.ABSTRACTUveal melanoma (UM), arising from intraocular melanocytes, poses a complex clinical challenge with a substantial risk of distant metastasis, often to the liver. Molecular profiling, encompassing genetic, cytogenetic, gene expression, and immunological subsets, plays a pivotal role in determining prognoses. The evolving landscape includes promising systemic treatments, such as tebentafusp, a novel immune-modulating bispecific fusion protein, and targeted therapies. Combined regional and systemic approaches, including immune checkpoint inhibito...
Source: Cancer Journal - March 25, 2024 Category: Cancer & Oncology Authors: Mali Barbi Richard D Carvajal Craig E Devoe Source Type: research

Updates in the Management of Uveal Melanoma
Cancer J. 2024 Mar-Apr 01;30(2):92-101. doi: 10.1097/PPO.0000000000000708.ABSTRACTUveal melanoma (UM), arising from intraocular melanocytes, poses a complex clinical challenge with a substantial risk of distant metastasis, often to the liver. Molecular profiling, encompassing genetic, cytogenetic, gene expression, and immunological subsets, plays a pivotal role in determining prognoses. The evolving landscape includes promising systemic treatments, such as tebentafusp, a novel immune-modulating bispecific fusion protein, and targeted therapies. Combined regional and systemic approaches, including immune checkpoint inhibito...
Source: Cancer Journal - March 25, 2024 Category: Cancer & Oncology Authors: Mali Barbi Richard D Carvajal Craig E Devoe Source Type: research