Loquat (Eriobotrya japonica) allergy, including anaphylaxis, is induced by a Bet v1 homolog.
PMID: 31017106 [PubMed - as supplied by publisher] (Source: Journal of Investigational Allergology and Clinical Immunology)
Source: Journal of Investigational Allergology and Clinical Immunology - April 23, 2019 Category: Allergy & Immunology Authors: Takaoka Y, Kondo Y, Matsunaga K, Aoki Y, Hasegawa E, Tokuda R, Fujisawa T, Morikawa A, Doi S Tags: J Investig Allergol Clin Immunol Source Type: research

Recombinant polyphenol oxidases for production of theaflavins from tea polyphenols.
Abstract Theaflavins (TFs) have attracted much attention due to their various bioactivities in black tea. This paper describes the first trial for enzymatic production of TFs by recombinant polyphenol oxidases (PPOs). PPO genes were cloned from nine species and expressed in E. coli. Crude enzyme assays by LC-MS revealed that eight recombinant PPOs were active for TFs production from tea polyphenols as substrates. Much higher activities were observed for crude enzymes of Md2 from Malus domestica (apple), Pp4 from Pyrus pashia (pear), and Ej2 from Eriobotrya japonica (loquat). When immobilized on mesoporous ...
Source: International Journal of Biological Macromolecules - April 21, 2019 Category: Biochemistry Authors: Zeng J, Du G, Shao X, Feng KN, Zeng Y Tags: Int J Biol Macromol Source Type: research

[ASAP] Ursolic Acid Isolated from the Leaves of Loquat ( < italic toggle="yes" > Eriobotrya japonica < /italic > ) Inhibited Osteoclast Differentiation through Targeting Exportin 5
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.8b06954 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - March 18, 2019 Category: Food Science Authors: Hui Tan, Chong Zhao, Qinchang Zhu, Yoshinori Katakura, Hiroyuki Tanaka, Koichiro Ohnuki, Kuniyoshi Shimizu Source Type: research

Dielectric relaxation of Mediterranean Lignocellulosic Fibers for Sustainable Functional Biomaterials
Publication date: Available online 1 March 2019Source: Materials Chemistry and PhysicsAuthor(s): Osama Fares, Faris M. AL-Oqla, Mohammed T. HayajnehAbstractGreen composite materials have become one of the most potential alternative solutions for various sustainable industries. Green bio-materials have the capability of being functional materials for wide range of high-tech applications including anti-bacterial food packaging, implantable sensors and energy harvesting devices due to their desired novel characteristics. In this work, the electrical characteristics of some of the most widely available Mediterranean lignocellu...
Source: Materials Chemistry and Physics - March 1, 2019 Category: Materials Science Source Type: research

Triterpenoid Acids from Eriobotrya japonica
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - February 20, 2019 Category: Chemistry Source Type: research

Neutrophil elastase inhibitory effects of pentacyclic triterpenoids from Eriobotrya japonica (loquat leaves)
ConclusionTCLL has a significant HNEI effect in vitro and a therapeutic effect on LPS-induced inflammation in a mouse model. Both the effects are more efficient than UA. Improved absorption of PTs in TCLL may be one explanation for these results.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - January 29, 2019 Category: Drugs & Pharmacology Source Type: research

Selection of the optimal reference genes for expression analyses in different materials of Eriobotrya japonica
Loquat (Eriobotrya japonica) is a subtropical tree bearing fruit that ripens during late spring and early summer, which is the off-season for fruit production. The specific flowering habit of loquat, which starts... (Source: Plant Methods)
Source: Plant Methods - January 28, 2019 Category: Biology Authors: Wenbing Su, Yuan Yuan, Ling Zhang, Yuanyuan Jiang, Xiaoqing Gan, Yunlu Bai, Jiangrong Peng, Jincheng Wu, Yuexue Liu and Shunquan Lin Tags: Research Source Type: research

Molecules, Vol. 24, Pages 448: Microscopic Analyses of Fruit Cell Plastid Development in Loquat (Eriobotrya japonica) during Fruit Ripening
Changjie Xu Plastids are sites for carotenoid biosynthesis and accumulation, but detailed information on fruit plastid development and its relation to carotenoid accumulation remains largely unclear. Here, using Baisha (BS; white-fleshed) and Luoyangqing (LYQ; red-fleshed) loquat (Eriobotrya japonica), a detailed microscopic analysis of plastid development during fruit ripening was carried out. In peel cells, chloroplasts turned into smaller chromoplasts in both cultivars, and the quantity of plastids in LYQ increased by one-half during fruit ripening. The average number of chromoplasts per peel cell in fully ripe fr...
Source: Molecules - January 27, 2019 Category: Chemistry Authors: Pengjun Lu Ruqian Wang Changqing Zhu Xiumin Fu Shasha Wang Don Grierson Changjie Xu Tags: Communication Source Type: research

Hepatoprotective Effect of Eriobotrya japonica Leaf Extract and Its Various Fractions against Carbon Tetra Chloride Induced Hepatotoxicity in Rats.
Authors: Shahat AA, Ullah R, Alqahtani AS, Alsaid MS, Husseiny HA, Al Meanazel OTR Abstract Eriobotrya japonica is traditionally used as an antipyretic, digestive, and diuretic agent. Its flowers possess free radical-scavenging, antioxidative, and hepatoprotective effects. We investigated the hepatoprotective potential of E. japonica leaf extract and its various fractions against hepatotoxicity in rats. Liver injury was stimulated by the oral administration of carbon tetrachloride (CCl4; 2.5 mL/kg b.wt.). Male albino rats (n = 55) were distributed arbitrarily into 11 groups: Group I, normal control group; ...
Source: Evidence-based Complementary and Alternative Medicine - January 17, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Floral nectar chitinase is a potential marker for monofloral honey botanical origin authentication: a case study from loquat (Eriobotrya japonica Lindl.)
Publication date: Available online 3 January 2019Source: Food ChemistryAuthor(s): Yue-Qin Song, Richard I Milne, Hong-Xia Zhou, Xue-Long Ma, Jiang-Yu Fang, Hong-Guang ZhaAbstractHoney,as a commercial product, is a target of adulteration through inappropriate production practices and deliberate mislabelling of botanical origin. Floral nectar protein could be a good marker for determining the source flowers of honey, especially monofloral honeys. Here, nectar and monofloral honey from Eriobotrya japonica Lindl. (loquat) were systematically compared, especially regarding proteomic and enzymatic activity. Using two-dimensional...
Source: Food Chemistry - January 3, 2019 Category: Food Science Source Type: research

Genes, Vol. 9, Pages 639: De Novo Analysis Reveals Transcriptomic Responses in Eriobotrya japonica Fruits during Postharvest Cold Storage
This study aimed to explore the changes of loquat transcriptome during long-term cold storage. Our results showed that the gene expression patterns were differed among the five stages. The differentially expressed genes (DEGs) in response to cold storage were more intense and complex in earlier stage. The membrane-related genes preferentially responded to low temperature and were followed by intracellular-located genes. The cold-induced pathways were mainly concerned with signal transduction and secondary metabolism (i.e., lignin, pectin, cellulose, terpenoid, carotenoid, steroid) in the first three stages and were chiefly...
Source: Genes - December 17, 2018 Category: Genetics & Stem Cells Authors: Shoukai Lin Ti Wu Hailan Lin Yanqing Zhang Shichang Xu Jinge Wang Bisha Wu Yu Chen Suying Lin Dahe Lin Xiumei Wang Xiaoxu Zhao Jincheng Wu Tags: Article Source Type: research

In vitro and in vivo evaluation of the genotoxicity of Eriobotrya japonica leaf extract
Publication date: November 2018Source: Regulatory Toxicology and Pharmacology, Volume 99Author(s): Myung-Hwan Jeong, Nak-Won Seong, Jong-Yun Lee, Yong-Jae Kim, Na-Rae Shin, Jong-Choon KimAbstractEriobotrya japonica leaf is included in the Chinese Pharmacopoeia, and is widely used as a medicinal material in traditional medicine. The present study investigated the potential genotoxic effects of E. japonica leaf extract (EJE) using three standard battery systems. Genotoxicity tests were conducted following the test guidelines of the Organisation for Economic Cooperation and Development (OECD) and Ministry of Food and Drug Saf...
Source: Regulatory Toxicology and Pharmacology - October 5, 2018 Category: Toxicology Source Type: research

In vitro and in vivo evaluation of the genotoxicity of Eriobotrya japonica leaf extract.
Abstract Eriobotrya japonica leaf is included in the Chinese Pharmacopoeia, and is widely used as a medicinal material in traditional medicine. The present study investigated the potential genotoxic effects of E. japonica leaf extract (EJE) using three standard battery systems. Genotoxicity tests were conducted following the test guidelines of the Organisation for Economic Cooperation and Development (OECD) and Ministry of Food and Drug Safety (MFDS), with application of Good Laboratory Practice. The bacterial reverse mutation test was conducted using the pre-incubation method in the presence or absence of...
Source: Regulatory Toxicology and Pharmacology : RTP - September 27, 2018 Category: Toxicology Authors: Jeong MH, Seong NW, Lee JY, Kim YJ, Shin NR, Kim JC Tags: Regul Toxicol Pharmacol Source Type: research

Antidiabetic and antihyperlipidemic effects of the flower extract of Eriobotrya japonica in streptozotocin-induced diabetic mice and the potential bioactive constituents in vitro
This study was designed to evaluate the effects of flower extracts of Eriobotrya japonica (EJ) on diabetes and hyperlipidemia for 4 weeks in streptozotocin (STZ)-induced diabetic mice. EJ treatment significantly lowered levels of blood glucose, HbA1C, plasma triglyceride (TG), and total cholesterol (TC) but increased the size of the islets of Langerhans within the pancreas. Membrane expression levels of glucose transporter 4 (GLUT4) and phospho-Akt in the skeletal muscles from EJ-treated STZ mice were increased, but G6Pase mRNA levels were decreased, contributing to EJ’s antidiabetic activity. EJ caused an increase in ...
Source: Journal of Functional Foods - August 22, 2018 Category: Nutrition Source Type: research

Generation of (2-Nitroethyl)benzene and related benzenoids from L-Phenylalanine; flower scents of the Japanese Loquat Eriobotrya japonica [Rosales: Rosaceae].
Abstract (2-Nitroethyl)benzene, methyl 4-methoxybenzoate and 4-methoxybenzaldehyde have been known as major scent components in flowers of the Japanese loquat Eriobotrya japonica [Rosales: rosaceae], together with 13 related benzenoids, including Z- and E-2-phenylacetaldoxime and benzyl alcohol. The scents air-trapped from a flowering panicle during 24 h incubation with d8-L-phenylalanine were composed of 15 deuterium labeled compounds {d6-styrene, d5-benzaldehyde, d7-2-phenylacetaldehyde, methyl d5-benzoate, d7 -2-phenylethanol, d7-2-phenylacetonitrile, d4-1,4-dimethoxybenzene, d7-Z-2-phenylacetaldoxime,...
Source: Bioscience, Biotechnology, and Biochemistry - July 25, 2018 Category: Biochemistry Authors: Kuwahara Y, Asano Y Tags: Biosci Biotechnol Biochem Source Type: research