Tomato Phytonutrients Balance UV Response: Results from a Double-Blind, Randomized, Placebo-Controlled Study
Conclusion: This well-tolerated carotenoid-containing supplement significantly protected against UVB-induced erythema formation and upregulation of proinflammatory cytokines in healthy volunteers.Skin Pharmacol Physiol 2019;32:101 –108 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - March 7, 2019 Category: Dermatology Source Type: research
Dehydroabietic Acid Induces Regeneration of Collagen Fibers in Ultraviolet B-Irradiated Human Dermal Fibroblasts and Skin Equivalents
Conclusion: Our results suggest that DAA could be a useful agent for improving skin photoaging through the protection and regeneration of collagen fibers in skin.Skin Pharmacol Physiol 2019;32:109 –115 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - March 7, 2019 Category: Dermatology Source Type: research
Quantitative Analysis of Free Amino Acids and Urea Derived from Isolated Corneocytes of Healthy Young, Healthy Aged, and Diseased Skin
Conclusion: This study suggests that the levels of FAAs and urea in the skin are affected by age and skin conditions (healthy/diseased). However, further studies are needed to show the effects of different skin conditions on the levels of FAAs and urea.Skin Pharmacol Physiol 2019;32:94 –100 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - February 15, 2019 Category: Dermatology Source Type: research
Development of a Novel Approach to Studying Corneodesmosomes and Stratum Corneum Adhesion: Extending Knowledge on the Pathophysiology of Sensitive Skin
Conclusion: The developed novel and easy-to-apply approach allows investigation of corneodesmosome components. We confirm a role of altered corneocytes in the pathomechanism of SS. The disclosed protocol can further be optimized in studies of skin conditions with strongly affected corneodesmosomes.Skin Pharmacol Physiol 2019;32:81 –93 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - January 27, 2019 Category: Dermatology Source Type: research
Reconstructed Human Epidermis Predicts Barrier-Improving Effects of < b > < i > Lactococcus lactis < /i > < /b > Emulsion in Humans
Conclusions:Lactococcus emulsion improved the skin barrier function with good biocompatibility. Moreover, our study exemplifies the translational predictive capacity of testing on RHE with respect toLactococcus emulsion.Skin Pharmacol Physiol 2019;32:72 –80 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - January 13, 2019 Category: Dermatology Source Type: research
Influence of Storage and Preservation Techniques on Egg-Derived Carotenoids: A Substantial Source for Cutaneous Antioxidants
In conclusion, RRS is suitable for monitoring egg-derived carotenoid levels, and carotenoid levels in eggs are generally stable under common storage and preservation modalities. Boiling in contrast to broiling of eggs might be superior in terms of carotenoid preservation within food processing.Skin Pharmacol Physiol 2019;32:65 –71 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - January 4, 2019 Category: Dermatology Source Type: research
Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata
Conclusion: This comprehensive work shows that the role of oxidative stress is very important in the pathogenesis of AA. In this study, we believe that we clarified the pathogenesis of oxidative stress for AA patients by investigating the TAS, TOS, OSI levels, PON1, arylesterase and prolidase enzyme activity parameters.Skin Pharmacol Physiol 2019;32:59 –64 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - December 13, 2018 Category: Dermatology Source Type: research
Current Data on Effects of Long-Term Missions on the International Space Station on Skin Physiological Parameters
Conclusion: In conclusion, we found that spaceflight under present conditions has no negative impact on skin physiological parameters.Skin Pharmacol Physiol 2019;32:43 –51 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - November 28, 2018 Category: Dermatology Source Type: research
Self-Reported Skin Changes by a Selected Number of Astronauts after Long-Duration Mission on ISS as Part of the Skin B Project
Conclusion: Based on these preliminary data, it is important to pay more attention to skin hygiene and maintenance in space.Skin Pharmacol Physiol 2019;32:52 –57 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - November 28, 2018 Category: Dermatology Source Type: research
In vivo Human Skin Penetration of the UV Filter Ethylhexyl Triazone: Effect of Lipid Microparticle Encapsulation
Conclusion: For the cream with the nonencapsulated sunscreen agent, the percentage of the applied EHT dose diffused into the stratum corneum was 21.9 ± 4.9%, not significantly different from that of the smaller-molecular-weight OMC (22.2 ± 7.6%) and BMDBM (20.5 ± 3.7%). A marked (45.7%) and statistically significant reduction in the in vivo skin penetration of EHT was attained with the cream containing microencapsulated EHT. The decreased perc utaneous penetration provided by the LMs should favor the efficacy of EHT and limit potential toxicological risks.Skin Pharmacol Physiol 2019;32:22 –31 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - October 31, 2018 Category: Dermatology Source Type: research
ZnO:SBA-15 Nanocomposites for Potential Use in Sunscreen: Preparation, Properties, Human Skin Penetration and Toxicity
Conclusion: Due to their suitable physicochemical properties and improved safety compared to bare ZnO nanoparticles, the ZnO:SBA-15 nanocomposites show promise for use in cosmetic applications.Skin Pharmacol Physiol 2019;32:32 –42 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - October 31, 2018 Category: Dermatology Source Type: research
Effect of Physical and Chemical Hair Removal Methods on Skin Barrier Function in vitro: Consequences for a Hydrophilic Model Permeant
Conclusion: Considering CRS and diffusion cell data, a moderate if significant decrease in skin barrier function was found after hair removal by dry shaving (physical skin/material interaction) and epilation methods (plucking out the entire hair, for example, by electrical epilation and waxing). Subsequent experiments will include testing of different permeants covering a broad range of physicochemical properties in vitro and confirming our findings in vivo.Skin Pharmacol Physiol 2019;32:8 –21 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - October 19, 2018 Category: Dermatology Source Type: research
Moisturizers versus Current and Next-Generation Barrier Repair Therapy for the Management of Atopic Dermatitis
We compare here the principal characteristics of over-the-counter moisturizers with physiologic lipid-based barrier repair therapy. Moisturizers are standard ancillary therapy for anti-inflammatory skin disorders, like atopic dermatitis (AD), and can attenuate the emergence of AD, the initial step in the “atopic march.” But not all moisturizers are beneficial; some can make skin function worse, and can even induce inflammation, possibly accounting for the frequent occurrence of “sensitive skin” in women. In contrast, physiologic lipid-based barrier repair therapy, if comprised of the 3 key s tratum corneum lipids, ...
Source: Skin Pharmacology and Physiology - October 18, 2018 Category: Dermatology Source Type: research
Acknowledgment to the Reviewers
Skin Pharmacol Physiol 2018;31:337 –338 (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - October 9, 2018 Category: Dermatology Source Type: research
Contents Vol. 31, 2018
Skin Pharmacol Physiol 2018;31:I –IV (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - October 9, 2018 Category: Dermatology Source Type: research
