Blue Lagoon Algae Improve Uneven Skin Pigmentation: Results from in vitro Studies and from a Monocentric, Randomized, Double-Blind, Vehicle-Controlled, Split-Face Study
Conclusion: Thus,BL algae can affect human melanocyte function in vitro and reduce uneven facial skin pigmentation in vivo.Skin Pharmacol Physiol (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 30, 2021 Category: Dermatology Source Type: research

Blue Lagoon Algae improve uneven skin pigmentation: Results from in vitro studies and from a monocenter, randomized, double blind, vehicle controlled, split-face study
(Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 30, 2021 Category: Dermatology Source Type: research

A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
(Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 19, 2021 Category: Dermatology Source Type: research

In vitro and in vivo Effect of Platelet-Rich Plasma-Based Autologous Topical Serum on Cutaneous Wound Healing
Conclusion: This preliminary study suggests that ES might promote cutaneous wound healing and may be useful for accelerating the re-epithelization of skin ulcers.Skin Pharmacol Physiol (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 9, 2021 Category: Dermatology Source Type: research

Effects of Intermittent Treatment with Topical Corticosteroids and Calcineurin Inhibitors on Epidermal and Dermal Thickness Using Optical Coherence Tomography and Ultrasound
Conclusions: MPA, HC, and PIM may be more suitable for repeated and prolonged treatment, especially in chronic diseases. (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 8, 2021 Category: Dermatology Source Type: research

Effects of intermittent treatment with topical corticosteroids and calcineurin inhibitors on epidermal and dermal thickness using optical coherence tomography and ultrasound
(Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 8, 2021 Category: Dermatology Source Type: research

Alpha-Tocopherol Protects Human Dermal Fibroblasts by Modulating Nitric Oxide Release, Mitochondrial Function, Redox Status, and Inflammation
Conclusion:α-Tocopherol exerts protective effects in HDF which underwent oxidative stress by modulating the redox status, inflammation, iNOS-dependent NO release, and mitochondrial function. These observations have a potential role in the prevention and treatment of photoaging-related skin cancers.Skin Pharmacol Physiol (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 8, 2021 Category: Dermatology Source Type: research

Copper Ions Ameliorated Thermal Burn-Induced Damage in ex vivo Human Skin Organ Culture
Conclusion: The deterioration of the zone of stasis and the increase in wound size following burning may be prevented or reduced by using copper ion-based therapeutic interventions.Skin Pharmacol Physiol (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 8, 2021 Category: Dermatology Source Type: research

Assessment of Skin Photoallergy Risk in Cosmetics Containing Herbal Extract Ingredients
Conclusion: We have shown thatCoptis, shikonin, or curcumin at 5% concentration in cosmetics could be applied safely without inducing contact allergic and photosensitive reactions on the skin. These findings advance the understanding of herbal extract use in cosmetic ingredients as related to the fields of dermatopharmacology and dermatotoxicology.Skin Pharmacol Physiol (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - July 1, 2021 Category: Dermatology Source Type: research

Topical α-Gal Nanoparticles Enhance Wound Healing in Radiated Skin
(Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - June 24, 2021 Category: Dermatology Source Type: research

Inhibitory Effects of Chitosan on Sebum Production on Facial Skin
(Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - June 23, 2021 Category: Dermatology Source Type: research

Lower limb dynamic activity significantly reduces foot skin perfusion – exploring data with different optical sensors in age-grouped healthy adults
(Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - June 21, 2021 Category: Dermatology Source Type: research

MiR-221-3p as a Potential Biomarker for Patients with Psoriasis and Its Role in Inflammatory Responses in Keratinocytes
Conclusion: MiR-221-3p is a latent biomarker of psoriasis patients. Lower expression of miR-221-3p inhibits the cell proliferation and inflammatory responses of HaCaT cells, which offers a possible target for the therapeutic interventions of psoriasis.Skin Pharmacol Physiol (Source: Skin Pharmacology and Physiology)
Source: Skin Pharmacology and Physiology - June 4, 2021 Category: Dermatology Source Type: research

Effects of Spaceflight on Human Skin
During both short- and long-duration spaceflight, several health problems can occur, including those of the skin. Astronauts in space and after returning to earth experience erythematous, burning, itchy, dry, sensitive, and thinning skin. Other skin problems, such as infections, abrasions, lacerations, delayed wound healing, and accelerated skin aging, are also common. Human skin is an ecosystem composed of a wide range of habitats for bacteria, fungi, and viruses called microbiome, which not only show a strong skin site-specific preference but also serve as microbial fingerprints that are highly unique to individuals. The...
Source: Skin Pharmacology and Physiology - May 31, 2021 Category: Dermatology Source Type: research

A Melanocortin-4 Receptor Agonist Induces Skin and Hair Pigmentation in Patients with Monogenic Mutations in the Leptin-Melanocortin Pathway
We report the results of a maximum treatment duration of 46 months. Skin pigmentation increased in all treated patients, as confirmed by spectrophotometry. During continuous treatment, the current results indicate that elevated tanning intensity levels may stabilize over time. Lips and nevi also darkened. In red-haired study participants, hair color changed to brown after initiation ofsetmelanotide treatment.Discussion:Setmelanotide treatment leads to skin tanning and occasionally hair color darkening in both POMC- and LEPR-deficient patients. No malignant skin changes were observed in the patients of this study. However, ...
Source: Skin Pharmacology and Physiology - May 31, 2021 Category: Dermatology Source Type: research