Report of plasmid-mediated colistin resistance in Klebsiella oxytoca from Iran
Conclusion: A high rate of carbapenem resistance and emergence of colistin resistance which have been located on mobile genetic elements is a concern. Detection, surveillance and control of multidrug-resistant Enterobacteriacea spread are essential to eradicate due infections. (Source: Reviews in Medical Microbiology)
Source: Reviews in Medical Microbiology - March 27, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Microbial pathogenesis and biofilm mediated by Enterococcus
Enterococcus have emerged as antibiotic resistant in nosocomial infections, food pollutant and also found in root canal teeth. The presence of virulence factors leads to spreading and survive in a hospital or other environments. Different molecular studies have reported the importance of Enterococcus with putative virulence factors at infections. The host immune process is able to identify Enterococcus, although these virulence factors provided conditions to evasion from the immune system. Therefore, these determinants are the best candidates for new therapies strategy and controlling this problematic microorganism. (Sourc...
Source: Reviews in Medical Microbiology - March 27, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Zika virus
In this review, the authors present current knowledge and research on the Zika virus, including epidemiology, symptom manifestations (collectively referred as ‘Zika fever’), modes of transmission, as well as Zika-related complications including Guillain–Barré syndrome and congenital Zika syndrome. (Source: Reviews in Medical Microbiology)
Source: Reviews in Medical Microbiology - March 27, 2018 Category: Microbiology Tags: Virology Source Type: research

New Publications in Medical Microbiology
No abstract available (Source: Reviews in Medical Microbiology)
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Book Review Source Type: research

Production of antihypertensive (angiotensin I-converting enzyme inhibitory) peptides derived from fermented milk supplemented with WPC70 and Calcium caseinate by Lactobacillus cultures
The ability of proteolytic Lactobacillus strains to hydrolyze milk proteins to release angiotensin I-converting enzyme inhibitory peptides was evaluated. The peptide profiles were obtained from the 3 and 5 kDa water-soluble extract (WSE) and subsequently separated by reversed-phase high performance liquid chromatography. WSE of fermented milks supplemented with different levels of WPC70 and Calcium caseinate (1.0, 1.5, or 2.0%) were passed through 3 and 5 kDa ultra cutoff membrane for optimization of peptides production. WSE of permeates and retentates were analyzed for peptides production and angiotensin-converting en...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Molecular chaperones impacts in growth, metabolism, pathogenicity and production of virulence factors in bacterial pathogen
Molecular chaperones are proteins that assist the valence folding or evolution and also the assembly or activity of different organic compound structures. In bacterial cell, the folding of expressed proteins is mainly occurred by preserved cytosolic chaperones, namely trigger factor. Many chaperones consider heat shock proteins, that is proteins expressed in response to elevated temperatures or alternative cellular stresses. Molecular chaperones are proteins responsible for varied processes in microbial cells, as well as helping the folding of new synthesized proteins, each throughout and when translation, helping in polyp...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Role of the microbiota in cancer growth and necrosis: the challenges and opportunities of bacteriotherapy for cancer and its complications
Possessing a selective growth advantage by influencing proliferation barrier, immune system, metabolism, and cell proliferation and death in tissues, is a critical event in cancer formation, progression, and suppression, indicating that specific microbes and microbiotas may enhance or dwindle cancer susceptibility. A host's microbiota may affect not only immune responses in developing tumor environment by inducing proinflammatory or immunosuppressive events but also response to cancer diagnosis, treatment, and relevant complications. As gifts to both cancer biology and microbiology, increased interrogating technologies hav...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Absence of Zika virus in abortion and placental tissue in a German cohort
In this study, we verified the hypothesis that the Zika virus (ZIKV) so far solely occurs as an imported zoonosis and is not yet circulating in a cohort in Germany. We have tested tissue specimens from abortions and placentas collected from 300 patients treated at the gynecology department of our hospital. Not surprisingly, although control specimens tested positive for ZIKV by reverse transcription-PCR, none of the tissue specimens contained viral RNA, thus supporting the hypothesis that ZIKV spread is limited to tropical and subtropical areas. (Source: Reviews in Medical Microbiology)
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Virology Source Type: research

Molecular diagnosis of Zika virus infections
The association between Zika virus (ZIKV) infection and serious complications, such as microcephaly in infants and Guillain–Barre syndrome in adults, necessitates the availability of accurate diagnostic tests. Molecular testing for ZIKV RNA provides the most definitive diagnosis of infection. Since the onset of the ZIKV outbreak in the Americas, numerous commercially available assays and laboratory developed tests have been established for Zika RNA. Laboratories now have a wide variety of options available, and choices depend on their resources and patient needs. Molecular detection of Zika RNA however is complicated by ...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Virology Source Type: research

The role of serologic testing for Zika virus infection
Direct detection of Zika virus (ZIKV) nucleic acid with nucleic acid tests is definitive laboratory evidence of infection. Initial studies suggest that the ZIKV viremic period is limited, leading the Centers for Disease Control and Prevention to recommend that nucleic acid tests be utilized only up to 14 days postsymptom onset in serum and urine. The host immune response to flaviviruses, including to ZIKV, primarily targets the viral envelope (E) protein, which has three main domains (ED I–III). Recent studies suggest that neutralizing antibodies against the EDIII domain are relatively specific and potentially able to di...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Virology Source Type: research

New Publications in Medical Microbiology
No abstract available (Source: Reviews in Medical Microbiology)
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Book Review Source Type: research

Production of antihypertensive (angiotensin I-converting enzyme inhibitory) peptides derived from fermented milk supplemented with WPC70 and Calcium caseinate by Lactobacillus cultures
The ability of proteolytic Lactobacillus strains to hydrolyze milk proteins to release angiotensin I-converting enzyme inhibitory peptides was evaluated. The peptide profiles were obtained from the 3 and 5 kDa water-soluble extract (WSE) and subsequently separated by reversed-phase high performance liquid chromatography. WSE of fermented milks supplemented with different levels of WPC70 and Calcium caseinate (1.0, 1.5, or 2.0%) were passed through 3 and 5 kDa ultra cutoff membrane for optimization of peptides production. WSE of permeates and retentates were analyzed for peptides production and angiotensin-converting en...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Molecular chaperones impacts in growth, metabolism, pathogenicity and production of virulence factors in bacterial pathogen
Molecular chaperones are proteins that assist the valence folding or evolution and also the assembly or activity of different organic compound structures. In bacterial cell, the folding of expressed proteins is mainly occurred by preserved cytosolic chaperones, namely trigger factor. Many chaperones consider heat shock proteins, that is proteins expressed in response to elevated temperatures or alternative cellular stresses. Molecular chaperones are proteins responsible for varied processes in microbial cells, as well as helping the folding of new synthesized proteins, each throughout and when translation, helping in polyp...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Role of the microbiota in cancer growth and necrosis: the challenges and opportunities of bacteriotherapy for cancer and its complications
Possessing a selective growth advantage by influencing proliferation barrier, immune system, metabolism, and cell proliferation and death in tissues, is a critical event in cancer formation, progression, and suppression, indicating that specific microbes and microbiotas may enhance or dwindle cancer susceptibility. A host's microbiota may affect not only immune responses in developing tumor environment by inducing proinflammatory or immunosuppressive events but also response to cancer diagnosis, treatment, and relevant complications. As gifts to both cancer biology and microbiology, increased interrogating technologies hav...
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Bacteriology Source Type: research

Absence of Zika virus in abortion and placental tissue in a German cohort
In this study, we verified the hypothesis that the Zika virus (ZIKV) so far solely occurs as an imported zoonosis and is not yet circulating in a cohort in Germany. We have tested tissue specimens from abortions and placentas collected from 300 patients treated at the gynecology department of our hospital. Not surprisingly, although control specimens tested positive for ZIKV by reverse transcription-PCR, none of the tissue specimens contained viral RNA, thus supporting the hypothesis that ZIKV spread is limited to tropical and subtropical areas. (Source: Reviews in Medical Microbiology)
Source: Reviews in Medical Microbiology - January 1, 2018 Category: Microbiology Tags: Virology Source Type: research