Analysis of correlation factors influencing the outcome of initial 131I remnant ablative therapy in intermediate- to high-risk patients with papillary thyroid microcarcinoma
Objective
To investigate the factors influencing the outcome of initial 131I remnant ablative therapy in intermediate- to high-risk patients with papillary thyroid microcarcinoma (PTMC).
Methods
We divided 99 patients with PTMC who underwent total thyroidectomy into two groups according to their response to initial 131I remnant ablative therapy: excellent response (ER) and non-ER groups. Clinical and laboratory characteristics were collected and retrospectively analyzed using univariate and multivariate binary logistic regression. Receiver operator characteristic (ROC) curves and diagnostic cutoff values were an...
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Is there an added value for whole body scan combined with stimulated thyroglobulin testing for follow-up of differentiated thyroid cancer patients?
Background
Aim
The aim of this study was to evaluate the incidence of positive WBS in patients with negative stimulated thyroglobulin (sTg), to define the clinical characteristics of this group, and the association with disease outcome.
Methods
DTC patients who underwent surveillance with simultaneous sTg and WBS were included.
Results
Two hundred seventy-two patients were included. Age at diagnosis was 46.5 ± 15.2 years, 79% were female. Mean duration of follow-up was 11.6 ± 6.8 years. Patients were categorised according to stimulation test results: sTg(−)/WBS(−) in 192/272 (70.6%); sTg...
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Youtube videos for the most commonly applied radionuclide treatments: sufficient for patients as an information source?
Conclusion
Although high-quality videos about radionuclide treatments on YouTube may enlighten and motivate patients positively; it should be kept in mind that improper information may also be uploaded to this platform. Under the guidance of the European Association of Nuclear Medicine, it is necessary to generate an official video in English with multilingual subtitles. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Optimized cocktail of 90Y/177Lu for radionuclide therapy of neuroendocrine tumors of various sizes: a simulation study
Conclusion
Our work showed that to achieve a more uniform dose distribution within the tumor, 177Lu alone is more effective for small tumors. For medium and large tumors, a ratio of 90Y to 177Lu with more or less 177Lu, respectively, is recommended. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
18F-fluorodeoxyglucose PET and PET/computed tomography for the evaluation of immunoglobulin G4-related disease: a systematic review
Conclusion
Despite some limitations that affect our review, 18F-FDG PET or PET/CT demonstrated the ability to assess IgG4RD both at initial evaluation and after therapy. In general, no correlation between PET/CT parameters and IgG4 serum levels has been reported. A possible role for 18F-FDG PET/CT to drive differential diagnosis with other disease is starting to emerge. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Review Articles Source Type: research
Role of 68Ga and 18F PSMA PET/CT and PET/MRI in biochemical recurrence of prostate cancer: a systematic review of prospective studies
Conclusion
There is prospective evidence for efficacy of PSMA PET/CT and PET/MRI in localizing disease recurrence in BCR, which increases with increasing PSA level at the time of scanning. There are no reported significant adverse effects related to the PSMA PET ligands. There is evidence of major change in management but no evidence for whether this achieves any improvement in outcome. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Review Articles Source Type: research
Nuclear medicine in the management of superficial skin abnormalities and institutional experience
Keloid, hypertrophic scars and basal cell carcinoma (BCC) falls under the category of non-melanoma skin cancer. Intralesional steroids, external beam radiation therapy, 5-Fluorouracil, cryotherapy, laser, etc are the available treatment options. However, recurrence has been reported with each type of treatment mode. In the present article, various treatment modes have been discussed and institutional experience of Rhenium-188 skin patches for the treatment of keloids and BCC has been discussed. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 24, 2022 Category: Nuclear Medicine Tags: Review Articles Source Type: research
British Nuclear Medicine Society Spring Meeting 2022
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Abstracts Source Type: research
Performance and long-term consistency of five Galliform 68Ge/68Ga generators used for clinical Ga-68 preparations over a 4 year period
Conclusion
The ability to prepare in the hospital radiopharmacy high-purity and pharmaceutically acceptable 68Ga-radiolabeled probes on a routine basis facilitates patient access to precision imaging for clinical and research aims. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Predicting pathological response and overall survival in locally advanced gastric cancer patients undergoing neoadjuvant chemotherapy: the role of PET/computed tomography
Conclusions
Metabolic parameters obtained with F-18 FDG PET/CT scanning before and after NACT in LAGC patients can accurately predict PR and OS. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Test–retest repeatability and interobserver variation of healthy tissue metabolism using 18F-FDG PET/CT of the thorax among lung cancer patients
Conclusion
HT metabolism is stable in a test–retest scenario and has high interobserver agreement. SUVmean was the most stable metric in organs with low FDG uptake and SUVpeak in HTs with moderate uptake. Test–retest measurements in LV were highly variable irrespective of the SUV parameters used for measurements. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Pretherapy 18F-fluorodeoxyglucose positron emission tomography/computed tomography robust radiomic features predict overall survival in non-small cell lung cancer
Conclusion
Ten radiomic features were robust to segmentation methods and two of them (total lesion glycolysis and gray level zone length matrix_gray level non-uniformity) were independently associated with 2-year overall survival. Together with the clinical staging, these features could be utilized towards improved risk stratification of lung cancer patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Combined clinical and specific positron emission tomography/computed tomography-based radiomic features and machine-learning model in prediction of thymoma risk groups
Conclusions
This small dataset study has proposed a machine-learning model by MLP Classifier (ANN) analysis on 18F-FDG PET/CT images, which can predict low risk and high-risk thymoma. This study also demonstrated that the combination of clinical data and specific PET/CT-based radiomic features with image variables can predict thymoma risk groups. However, these results should be supported by studies with larger dataset. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Restoration of Tc-99m methyl diphosphonate bone scan image using Richardson–Lucy algorithm
Conclusion
Tc-99 m MDP bone scan images were restored to improve image quality using the Richardson–Lucy algorithm. The optimum value of the PSF parameter was found to be of size = 11 pixels and sigma = 1.75 pixels. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Comparison of reprojected bone SPECT/CT and planar bone scintigraphy for the detection of bone metastases in breast and prostate cancer
Conclusion
Whole-body bone SPECT/CT can be reprojected into more familiar anterior and posterior planar images with excellent sensitivity for bone metastases, making additional acquisition of planar BS unnecessary. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - April 18, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
