Derivation and validation of a 18F-FDG PET/CT scoring model to predict malignant pleural effusion
Conclusions The PET/CT scoring model is a valuable strategy to help physicians to distinguish malignant–benign pleural effusion and stratify patients who will benefit from invasive procedures. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The impact of 18F-fluorodeoxyglucose PET/computed tomography on clinical staging in bladder cancer
Conclusion 18F-FDG PET/CT can potentially change the clinical stage determined by CT and MRI when used for staging in bladder cancer, and can lead to nodal up-staging particularly in cases with muscle-invasive bladder cancer. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Reduction of radiation accumulation in salivary glands through oral vitamin C during 68Ga-PSMA-11 total-body dynamic PET/CT imaging
Conclusion Oral vitamin C could reduce the accumulation of radiation in the salivary glands during 68Ga-PSMA-11 total-body dynamic PET/CT imaging. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Accurate measurement of coronary artery calcium in cancer patients using the CT component of PET/CT scans
Conclusion Estimation of CAC from the CT component of PET/CT scans is a reliable method for the detection of significant CAC in cancer patients and correlates well with the standard method. This technique should permit the calculation of cardiovascular risk in cancer patients undergoing PET/CT without any additional radiation exposure. A significant number of asymptomatic low-to-intermediate-risk cancer patients were found to have a high risk of cardiovascular disease. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Reference values of mandibular condylar growth activity: a study of SUVmax with quantitative bone SPECT/CT
Conclusions The condylar SUVmax varied with age. Different cutoff values of condylar SUVmax should be employed for diagnosing active UCH for patients in different ages. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Postoperative radioiodine therapy impact on survival in poorly differentiated thyroid carcinoma: a population-based study
Purpose The true impact of postoperative radioiodine therapy on survival has been controversial for patients with poorly differentiated thyroid carcinoma (PDTC). We aimed to determine the impact of postoperative radioiodine on survival in PDTC through a population-based study. Methods Data on patients with PDTC were collected from the US SEER database (2004 to 2015). Patients were divided into the radioiodine group and nonradioiodine group. Survival comparison between groups was evaluated by Kaplan–Meier curves, log-rank test and multivariate Cox regression analysis. Akaike information criterion was used to se...
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Tandem high-dose 131I-MIBG therapy supported by dosimetry in pediatric patients with relapsed-refractory high-risk neuroblastoma: the Bambino Gesu’ Children’s Hospital experience
Conclusion High-dose 131I-MIBG therapy combined with chemotherapy represent a well-tolerated and effective modality of treatment in heavily pretreated patients affected by relapsed/refractory NBL. However, further studies, including a wider cohort of patients, are needed. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

18F-FDG PET/CT for the evaluation of male breast cancer: a systematic review
Conclusion Despite some limitations affecting our review, 18F-FDG PET/CT seems to be a valuable tool to assess MBC. Further research studies are required to better underline the role of hybrid imaging with 18F-FDG for the evaluation of MBC, especially in comparison with female breast cancer. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 24, 2022 Category: Nuclear Medicine Tags: Review Article Source Type: research

Relationship between total lesion glycolysis of primary lesions based on 18F-FDG PET/CT and lymph node metastasis in gastric adenocarcinoma: a cross-sectional preliminary study
Objectives We explored the relationship between lymph node metastasis (LNM) and total lesion glycolysis (TLG) of primary lesions determined by 18fluoro-2-deoxyglucose PET/computed tomography (18F-FDG PET/CT) in patients with gastric adenocarcinoma, and evaluated the independent effect of this association. Methods This retrospective study included 106 gastric adenocarcinoma patients who were examined by preoperative 18F-FDG PET/CT imaging between April 2016 and April 2020. We measured TLG of primary gastric lesions and evaluated its association with LNM. Multivariate logistic regression and a two-piece-wise linea...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The role of fluorodeoxyglucose-PET/computed tomography as a predictor of breast cancer characteristics and prognosis
Conclusion In this study, we showed that the SUVmax of FDG-PET/CT was a useful predictor of lymph node metastasis and breast cancer prognosis. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The value of preoperative 18F-FDG PET metabolic and volumetric parameters in predicting microvascular invasion and postoperative recurrence of hepatocellular carcinoma
Background Microvascular invasion (MVI) is very important in the evaluation of hepatocellular carcinoma (HCC), but diagnosis is determined by postoperative pathology; thus, preoperative noninvasive methods will play an active role. The purpose of the study was to assess the performance of metabolic parameters of preoperative 18F-fluorodeoxyglucose PET/computerized tomography (18F-FDG PET/CT) in the prediction of MVI and postoperative recurrence in primary hepatocellular carcinoma. Methods We retrospectively collected 72 patients with HCC who have performed 18F-FDG PET/CT scan before partial hepatectomy between 2...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Clinical usefulness of PET/MRI in differentiating anterior mediastinal masses
Objectives To investigate the clinical usefulness of 18F-fluorodeoxyglucose (FDG) PET/MRI in differentiating anterior mediastinal lesions, including small ones. Material and methods Among 96 patients who underwent 18F-FDG PET/MRI screening for anterior mediastinal lesions, we retrospectively reviewed images of 42 patients with histologically or clinically diagnosed thymic carcinomas, thymomas or anterior mediastinal cysts. MRI findings and maximum standardized uptake value (SUVmax) were compared among the three categories. In addition, small lesions measuring (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Interreader agreement in evaluation of 68Ga-PSMA PET/CT at the time of initial staging: comparison of the three evaluation criteria in the pretreatment risk groups
Objective The aim of this study was to assess the interreader agreement in evaluation 68Ga-prostate-specific membrane antigen (PSMA) PET/CT according to three current criteria European association of nuclear medicine, PROMISE with miTNM, and PSMA-RADS in newly diagnosed prostate cancer (PC) patients. Methods The images of 101 patients who had been diagnosed with PC and underwent 68Ga-PSMA PET/CT at the time of initial staging were evaluated according to the three interpretation criteria by two nuclear medicine specialists. Local tumor, pelvic lymph node metastasis and distant metastasis were evaluated separately...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Lesion detection in 18F-sodium fluoride bone imaging: a comparison of attenuation-corrected versus nonattenuation-corrected PET reconstructions from modern PET-CT systems
Conclusion AC PET data provided superior lesion detection to NAC in NaF bone examinations and are thus required for clinical interpretation. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The association between lesion tracer uptake on 68Ga-DOTATATE PET with morphological response to 177Lu-DOTATATE therapy in patients with progressive metastatic neuroendocrine tumors
Conclusion In patients with SSTR-RADS 5 PM-NETs treated with 177Lu-DOTATATE, there was similar response to therapy for all lesions with PET-generated Krenning score ≥2. No correlation was found between lesion’s POD and level of tracer uptake. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research