Relationship between total lesion glycolysis of primary lesions based on 18F-FDG PET/CT and lymph node metastasis in gastric adenocarcinoma: a cross-sectional preliminary study
Objectives
We explored the relationship between lymph node metastasis (LNM) and total lesion glycolysis (TLG) of primary lesions determined by 18fluoro-2-deoxyglucose PET/computed tomography (18F-FDG PET/CT) in patients with gastric adenocarcinoma, and evaluated the independent effect of this association.
Methods
This retrospective study included 106 gastric adenocarcinoma patients who were examined by preoperative 18F-FDG PET/CT imaging between April 2016 and April 2020. We measured TLG of primary gastric lesions and evaluated its association with LNM. Multivariate logistic regression and a two-piece-wise linea...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
The role of fluorodeoxyglucose-PET/computed tomography as a predictor of breast cancer characteristics and prognosis
Conclusion
In this study, we showed that the SUVmax of FDG-PET/CT was a useful predictor of lymph node metastasis and breast cancer prognosis. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
The value of preoperative 18F-FDG PET metabolic and volumetric parameters in predicting microvascular invasion and postoperative recurrence of hepatocellular carcinoma
Background
Microvascular invasion (MVI) is very important in the evaluation of hepatocellular carcinoma (HCC), but diagnosis is determined by postoperative pathology; thus, preoperative noninvasive methods will play an active role. The purpose of the study was to assess the performance of metabolic parameters of preoperative 18F-fluorodeoxyglucose PET/computerized tomography (18F-FDG PET/CT) in the prediction of MVI and postoperative recurrence in primary hepatocellular carcinoma.
Methods
We retrospectively collected 72 patients with HCC who have performed 18F-FDG PET/CT scan before partial hepatectomy between 2...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Clinical usefulness of PET/MRI in differentiating anterior mediastinal masses
Objectives
To investigate the clinical usefulness of 18F-fluorodeoxyglucose (FDG) PET/MRI in differentiating anterior mediastinal lesions, including small ones.
Material and methods
Among 96 patients who underwent 18F-FDG PET/MRI screening for anterior mediastinal lesions, we retrospectively reviewed images of 42 patients with histologically or clinically diagnosed thymic carcinomas, thymomas or anterior mediastinal cysts. MRI findings and maximum standardized uptake value (SUVmax) were compared among the three categories. In addition, small lesions measuring (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Interreader agreement in evaluation of 68Ga-PSMA PET/CT at the time of initial staging: comparison of the three evaluation criteria in the pretreatment risk groups
Objective
The aim of this study was to assess the interreader agreement in evaluation 68Ga-prostate-specific membrane antigen (PSMA) PET/CT according to three current criteria European association of nuclear medicine, PROMISE with miTNM, and PSMA-RADS in newly diagnosed prostate cancer (PC) patients.
Methods
The images of 101 patients who had been diagnosed with PC and underwent 68Ga-PSMA PET/CT at the time of initial staging were evaluated according to the three interpretation criteria by two nuclear medicine specialists. Local tumor, pelvic lymph node metastasis and distant metastasis were evaluated separately...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Lesion detection in 18F-sodium fluoride bone imaging: a comparison of attenuation-corrected versus nonattenuation-corrected PET reconstructions from modern PET-CT systems
Conclusion
AC PET data provided superior lesion detection to NAC in NaF bone examinations and are thus required for clinical interpretation. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
The association between lesion tracer uptake on 68Ga-DOTATATE PET with morphological response to 177Lu-DOTATATE therapy in patients with progressive metastatic neuroendocrine tumors
Conclusion
In patients with SSTR-RADS 5 PM-NETs treated with 177Lu-DOTATATE, there was similar response to therapy for all lesions with PET-generated Krenning score ≥2. No correlation was found between lesion’s POD and level of tracer uptake. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Comparison of 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT in the staging and restaging of gastric adenocarcinoma
Conclusion
68Ga-FAPI-04 PET/CT is an imaging modality with the potential of yielding more sensitive and specific findings 18F-FDG PET/CT. This modality may help avoid invasive diagnostic procedures that may be frequently required in GAc. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
FDG PETCT for assessing marrow involvement at staging pediatric nonhematological round cell malignancies
Conclusion
FDG PETCT with sensitivity and NPV of 100% can be considered as a first stop imaging and biopsy can be avoided in patients with a negative scan. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Associations of whole-body 18F-FDG PET/CT parameters and SCC-Ag level with overall survival in patients with cervical cancer
Objective
To explore the whole-body metabolic tumour volume (WBMTV), whole-body total lesion glycolysis (WBTLG) and tumour whole-body maximum standardised uptake value (WBSUVmax) of post-treatment 18F-fluorodeoxyglucose PET/computed tomography (18F-FDG PET/CT) in predicting the overall survival (OS) in patients with cervical squamous cell carcinoma (SCC).
Methods
The clinical data of 74 patients with cervical SCC who received 18F-FDG PET/CT were retrospectively analysed. WBMTV, WBTLG and WBSUVmax, as well as the serum SCC-Ag level, were measured. The Kaplan–Meier method and Cox regression were used to analyse ...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Clinical and metabolic parameters for predicting disease progression of gallbladder adenocarcinoma
Conclusion
In GB adenocarcinoma, clinical stage and MTV are the most powerful parameters for predicting recurrence and disease progression. Based on clinical stage, MTV will represent a strong prognostic predictor. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Site-based performance of 131I-MIBG imaging and 99mTc-HYNIC-TOC scintigraphy in the detection of nonmetastatic extra-adrenal paraganglioma
Conclusions
131I-MIBG imaging could become the first-line investigation modality in patients with extra-adrenal abdominal paragangliomas. However, 99mTc-HYNIC-TOC scintigraphy has high sensitivity and is superior to 131I-MIBG imaging for detecting head & neck and thoracic paraganglioma. Both 131I-MIBG imaging and 99mTc-HYNIC-TOC scintigraphy have poor performance for detecting urinary bladder paragangliomas. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Prognostic value of lung shunt fraction in hepatocellular carcinoma and unresectable liver dominant metastatic colorectal cancer undergoing transarterial radioembolisation
Aim
To assess the overall survival and determine whether pre-TARE shunt fraction, tumor volume and tumor marker impact the outcome.
Methods
This is a retrospective study of 75 patients who were referred for 90Y-glass microsphere radioembolisation by a joint clinic decision between 1 January 2010 and 31 December 2014. All patients underwent pre-TARE CECT and 99mTc-MAA lung shunt fraction (LSF) imaging.
Results
Overall survival was 19 months for hepatocellular carcinoma (HCC) and 24 months for metastatic colorectal carcinoma. For hepatocellular carcinoma-LSF higher than 6.51 % was predictive of significantl...
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Three-dimensional semiquantitative analysis of gastric emptying SPECT
Conclusion
D-SPECT imaging can overcome the interference in the semiquantitative data of residual GE caused in 2D mode. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Impact of reconstruction parameters on spatial resolution and its comparison between cadmium-zinc-telluride SPECT/CT and conventional SPECT/CT
Conclusion
The spatial resolution was improved with the increase of iterations. Increasing the cutoff frequency of the Butterworth filter and decreasing the Gauss filter enhanced spatial resolution. The spatial resolution was better reconstructed by OSEM associated with attenuation correction, scatter correction and resolution recovery than FBP. CZT-SPECT/CT had better spatial resolution than conventional SPECT/CT. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 16, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
