Evaluation of 68Ga-PSMA PET/CT with Volumetric Parameters for Staging of Prostate Cancer Patients: Erratum
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Erratum Source Type: research
British Nuclear Medicine Society Autumn Meeting 2021
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Abstracts Source Type: research
In-house development, implementation and evaluation of machine learning software for automated clinical scan processing
Conclusion
This work demonstrates that established machine learning technology and modest hardware can be used to create automated segmentation tools that perform well in the clinic. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
18F-FDG PET/computed tomography scan in patients with suspicion of recurrent neuroendocrine carcinoma of the cervix
Conclusions
18F-FDG PET/CT is an efficient technique for detecting recurrent cervical neuroendocrine carcinoma, and may thus contribute to improving patient management. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Peptide-based 68Ga-PET radiotracer for imaging CD133 expression in colorectal cancer
Conclusion:
Rapid tumor CD133 detection and selectivity were demonstrated in vitro and in vivo with PET using the specific CD133 binding peptide 68Ga-DOTA-LS7. A robust correlation was detected in vivo between tumor signals from mouse xenograft models with different cell lines and CD133 expression. The favorable characteristics of 68Ga-DOTA-LS7, such as convenient synthesis and specific uptake, warrant its further investigation for CD133 expression imaging. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Improved 18-FDG PET/CT diagnosis of multiple myeloma diffuse disease by radiomics analysis
Conclusions
Radiomics analysis of 18-FDG PET/CT images with machine-learning overcame the limitations of visual analysis, providing a highly accurate and more reliable diagnosis of diffuse bone marrow infiltration in multiple myeloma patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Identification of specific SUVmax ratios enhances diagnostic accuracy for staging of intrathoracic nodes in lung cancer
Conclusion
In this relatively small sample, SUVmax LN/MBP 2.3 had a PPV of 100% for diagnosing malignant nodes. Using SUVmax ratios could obviate the need for staging EBUS in selected patients with resultant time and cost savings. Selecting different SUVmax ratios, chosen to provide high accuracies for the parameter of interest to change management, is a potentially powerful diagnostic tool that is overlooked when FDG uptake is only classified as ‘positive’ or ‘negative’. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
68Ga-PSMA-I&T-PET/CT interobserver and intraobserver agreement for prostate cancer: a lesion based and subregional comparison study among observers with different levels of experience
Conclusion
Interpretation of prostate-specific membrane antigen (PSMA) for prostate cancer is acceptably consistent among observers, but some details are noteworthy. The evaluation should be done more algorithmically for local tumors, since all observers showed relatively lower agreement. The agreement increased as prostate-specific antigen and Gleason score increased. The observer with PSMA experience (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Usefulness of PET-guided surgery with 64Cu-labeled cetuximab for resection of intrapancreatic residual tumors in a xenograft mouse model of resectable pancreatic cancer
Conclusions
OpenPET-guided surgery with 64Cu-labeled-cetuximab enabled intraoperative identification and resection of intrapancreatic small residual tumors. This technology could be useful to prevent tumor residuals during surgery and improve pancreatic cancer survival. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
18F-FDG-PET/CT analysis in hospitalized patients affected by pulmonary disease: The experience of the Nuclear Medicine Unit of “Policlinico Tor Vegata”
Conclusion
Data here reported showed the high accuracy of the F-FDG-PET/CT performed in our department, mainly for pulmonary diseases, also highlighting the importance of continuously updating the selection criteria for patients who need PET examinations. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Quantitative evaluation of single-photon emission computed tomography findings in lower extremity possible without computed tomography-based attenuation correction
Conclusions
In bone SPECT quantitative examinations of the lower extremity, quantitative evaluation without CTAC is possible without the use of scatter correction or resolution recovery. Thus, quantitative evaluation can be performed with use of a standalone SPECT device without CT. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Comparison of bone SPECT/CT and MRI in detection of pain generator in ankle and foot pain: a retrospective diagnostic study
Objective
To study the sensitivity and specificity of MRI and bone SPECT-CT in detecting the pain generator in ankle and foot pain with diagnostic dilemma.
Methods
Retrospectively data of patients with ankle or foot pain who underwent both MRI and Bone SPECT-CT were analyzed. The lesions and probable pain generator sites were reported as per MRI and bone SPECT-CT findings. These lesions were correlated clinically, managed accordingly and followed up. The patients who had significant improvement in response to the treatment provided were considered to have been diagnosed accurately. The foot and ankle disability ...
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Prospective evaluation of organ-specific dose and lesional doses following therapeutic [177Lu]Lu-EDTMP administration in patients with multiple skeletal metastases and its correlation with clinical hematological toxicity
Aim
In patients with multiple skeletal metastases, accurate estimation of absorbed doses to radiosensitive bone marrow in bone-directed systemic radionuclide therapies (RNT) is critically important from clinical dose determination standpoint. The primary aim of the present study was to estimate the radiation absorbed doses of therapeutic [177Lu]Lu-EDTMP to bone marrow by two methods viz. Medical Internal Radiation Dose (MIRD) schema and using OLINDA software and correlate with hematological toxicity.
Methods
A total of 15 patients diagnosed to have multiple painful skeletal metastases being treated with [177Lu]L...
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Reassessment of the lung dose limits for radioembolization
Radioembolization, also known as selective internal radiation therapy (SIRT), is an established treatment for the management of patients with unresectable liver tumors. Advances in liver dosimetry and new knowledge about tumor dose-response relationships have helped promote the well-tolerated use of higher prescribed doses, consequently transitioning radioembolization from palliative to curative therapy. Lung dosimetry, unfortunately, has not seen the same advances in dose calculation methodology and renewed consensus in dose limits as normal liver and tumor dosimetry. Therefore, the efficacy of curative radioembolization ...
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Review Article Source Type: research
BNMS position statement on molecular radiotherapy
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 23, 2021 Category: Nuclear Medicine Tags: Editorial Source Type: research
