Edge-preserving adaptive autoregressive model for Poisson noise reduction
Autoregressive models in image processing are linear prediction models that split an image into a predicted (i.e. filtered) image and a prediction error image, which extracts data on the image edges. Edge separation is a crucial feature of an autoregressive model. Data on the edges can be processed in different ways and then added to the filtered image. Another basic feature of our method is spatially varying modelling. In this short article, we propose an improved autoregressive model that preserves image sharpness around the edges of the image and focus on the reduction of Poisson noise, which degrades nuclear medicine i...
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Technical Notes Source Type: research
Comparison of ordered-subset expectation maximization and filtered back projection reconstruction based on quantitative outcome from dynamic [18F]NaF PET images
This study compares differences between quantitative outcomes at the hip derived from images reconstructed using the FBP and ordered-subset expectation maximization (OSEM) methods. Dynamic [18F]NaF PET data at the hip for four postmenopausal women were reconstructed using FBP and nine variations of the OSEM algorithm (all combinations of 1, 5, 15 iterations and 10, 15, 21 subsets). Seven volumes of interest were placed in the hip. Bone metabolism was measured using standardized uptake values, Patlak analysis (Ki-PAT) and Hawkins model Ki-4k. Percentage differences between the standardized uptake values and Ki values from F...
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Technical Notes Source Type: research
PET/computed tomography enterography
Interpretation of gastrointestinal PET/computed tomography (PET/CT) is often complicated by anatomy including bowel folds, flexures, variant redundancy, decompressed bowel segments and physiological uptake. This makes it very difficult to identify both true positives and true negatives, compromising both sensitivity and specificity. CT enterography is increasingly being integrated into the field of nuclear medicine to address these issues. This technique uses the combination of negative/neutral contrast to distend the lumen of the gut and iodinated contrast to enhance the gastrointestinal wall and pathological findings. Ap...
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Technical Notes Source Type: research
Differences in diagnostic impact of dual-tracer PET/computed tomography according to the extrahepatic metastatic site in patients with hepatocellular carcinoma
Objectives
We compared the diagnostic performance of C-11 acetate and F-18 fluorodeoxyglucose (FDG) PET/computed tomography (CT) for the detection of extrahepatic metastasis in patients with hepatocellular carcinoma (HCC) and evaluated whether the improvement in the diagnostic performance of dual tracer PET/CT differs by the metastatic site.
Methods
Fifty-eight patients who had extrahepatic metastasis on either C-11 acetate or F-18 FDG PET/CT were enrolled, and 193 metastatic lesions were analyzed in this retrospective study. The metastatic lesions were categorized based on six sites of involvement. According to...
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Clinical relevance of incidental focal breast uptake on fluorine-18 fluorodeoxyglucose PET/computed tomography studies: an experience in a high-load center of Spain
Conclusion
Although BIU detected by 18F-FDG PET/CT is infrequently found, the risk of malignancy remains very high (39.1%). Both SUVmax and maximum diameter were greater in malignant than in benign lesions. An exhaustive study with ultrasound/mammography and selective histopathological correlation is mandatory after BIU findings, even in small lesions. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Is 18F-FDG PET/CT capable of differential diagnosis from tuberculous pleurisy from malignant mesothelioma?
Conclusion
Intense pleural FDG uptake can be observed in TP like malignant mesothelioma. For the evaluation of the pleural pathologies in the tuberculosis endemic countries, it should be considered that FDG PET/CT may have false-positive results. Evaluation of increased pleural FDG uptake together with the detected parenchymal findings and lymphatic involvement may help us to make more accurate interpretation of the diagnosis. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Analysis of the F-18 FDG PET/CT features of pulmonary sclerosing pneumocytoma
Purpose
This retrospective study aimed to analyzed the F-18 fluorodeoxyglucose PET/computed tomography (F-18 FDG PET/CT) features of pulmonary sclerosing pneumocytoma (PSP) to improve the understanding and preoperative diagnostic efficacy of this rare disorder.
Methods
FDG PET/CT images from 11 patients with 22 lesions (including one patient with 12 lesions) proven PSP in our hospital were reviewed. We summarized the PET/CT features of PSP and analyzed the correlation between FDG uptake and tumor size.
Results
PET/CT imaging revealed all tumors located in each lobe of the two lungs randomly. All 22 tumors...
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Correlation between semiquantitative and volumetric 18F-FDG PET/computed tomography parameters and Ki-67 expression in breast cancer
Objectives
To evaluate the relationship between semiquantitative and volumetric parameters on 18F-FDG PET/computed tomography (CT), including maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), metabolic tumor volume (MTV), total lesion glycolysis (TLG), tumor to liver ratio (TLR) and tumor to mediastinum ratio (TMR) with the level of Ki-67 expression in breast cancer.
Patient and methods
We retrospectively reviewed 105 female patients with newly diagnosed breast cancer who underwent baseline 18F-FDG PET/CT and had immunohistochemical staining to determine the level of Ki-67 exp...
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Diagnostic utility of Ga-68 DOTA-SSTR and F-18 FDG PET/CT in the detection of culprit tumours causing osteomalacia: a systematic review and meta-analysis
Conclusion
In the detection of offending tumours in TIO, Ga-68 DOTA-SSTR PET/CT has better sensitivity than F-18 FDG PET/CT and should be used as first-line imaging modality due to very high sensitivity. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Prognostic value of pretreatment F-18 fluorodeoxyglucose PET/CT in colorectal cancer with unresectable metastasis
Purpose
The aim of the study was to assess the prognostic value of pretreatment PET/computed tomography (CT) scans in colorectal cancer (CRC) patients with unresectable metastasis.
Materials and methods
We retrospectively reviewed the pretreatment PET/CT images of 82 CRC patients with unresectable metastasis and their medical records. On PET/CT images, maximum standardized uptake value (SUVmax) of primary tumor, highest SUVmax of metastatic tumors and number of metastatic organs were identified. The patients were further divided into single and multiple organ metastases groups according to the extent of disease....
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
18F-choline PET-computed tomography for the prediction of early treatment responses to transarterial radioembolization in patients with hepatocellular carcinoma
Conclusions
Our preliminary results showed that changes in certain metabolic parameters (from baseline PET to 1-month PET) are predictive of the response to TARE in HCC (Delta SUVmean, delta TLG, and delta SUL). The absence of post-treatment inflammation could lead to a better prediction than MRI evaluation. This study suggests that 1-month 18F-choline PET/CT could modify the clinical management predicting responders.
Video Abstract: http://links.lww.com/NMC/A193 (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Role of post-therapy 99mTc-MIBI single-photon emission computed tomography/computed tomography scan in predicting survival in patients with high-grade glioma
Conclusion
In patients with HGG, post-therapy brain SPECT/CT with 99mTc-MIBI can provide useful prognostic information. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Investigation of Cushing’s and subclinical Cushing’s syndromes using adrenocortical scintigraphy
Conclusion
There were differences in the intake rates of adrenocortical scintigraphy between the Cushing’s syndrome group and subclinical Cushing’s syndrome group, making it possible to differentiate between the two using the intake rate. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
BRAFV600E mutation is associated with increased prevalence of contralateral lymph-node metastases in low and low-to-intermediate risk papillary thyroid cancer
Conclusion
This study suggests that BRAFV600E mutation represents a significant risk factor for developing contralateral lymph-node metastases and confirms that BRAFV600E mutation is associated with more aggressive PTC features and a higher prevalence of metastatic disease also in low or low-to-intermediate-risk PTC patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Advantages of gravity-assisted diuretic renogram: F + 10 (seated position) method
Discussion
F + 10(sp) method improves patient compliance avoiding bladder fullness-related problems, without need of catheterization. It allows for a more reliable quantification of the renal output, thanks to outflow indices that are favored by gravity effects. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - May 20, 2021 Category: Nuclear Medicine Tags: Review Articles Source Type: research
