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Neoadjuvant strategies for advanced pancreatic neuroendocrine tumors: should combined chemotherapy and peptide receptor radionuclide therapy be the preferred regimen for maximizing outcome?
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Letter to the Editor Source Type: research

Assessment of biological and clinical aggressiveness of invasive ductal breast cancer using baseline 18F-FDG PET/CT-derived volumetric parameters
Conclusion SUVmax may appropriately reflect the immunohistochemical characteristics of IDBC, whereas TLG is associated with clinical risk factors and systemic metastasis. Our preliminary findings suggesting different relationships between volumetric parameters and the clinical tumor size and the Ki-67 index for different subtypes require further evaluation. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Post-therapy lesions in patients with non-Hodgkin’s lymphoma characterized by 18F-FDG PET/CT-guided biopsy using automated robotic biopsy arm
Conclusion 18F-FDG PET/CT for response evaluation in NHL possesses a low PPV and hence warrants histopathological correlation when 18F-FDG PET/CT findings influence management decision. Diagnostic yield of 18F-FDG PET/CT-guided biopsy is high and has the potential to reduce sampling errors. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Utility of whole-body (head-to-toe) PET/CT in the evaluation of melanoma and sarcoma patients
Conclusion In patients with melanoma and sarcoma, inclusion of entire lower extremities adds little additional clinical value as detection of isolated, unexpected metastasis is rare. Brain imaging may add value as the presence of brain metastases alters clinical management. Overall, in patients with melanoma or sarcoma, whole-brain PET/CT imaging may be of value, but routine inclusion of the entire lower extremities adds little additional value. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Correlation between functional imaging markers derived from diffusion-weighted MRI and 18F-FDG PET/CT in esophageal cancer
Conclusion This study indicates that tumor cellularity derived from DW-MRI and tumor metabolism measured by 18F-FDG PET/CT are independent cellular phenomena in newly diagnosed esophageal cancer. Therefore, tumor ADC and SUV values may play complementary roles as imaging markers in the prediction of survival and evaluation of response to treatment in esophageal cancer. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Effect of postoperative radiotherapy on outcome in resectable stage IIIA-N2 non-small-cell lung cancer: an updated meta-analysis
Background In a previous meta-analysis-based modeling study, it was hypothesized that modern postoperative radiotherapy (PORT) may improve both local recurrence and overall survival (OS) in stage IIIA-N2 non-small-cell lung cancer (NSCLC). There were only four single-arm trials with a total of 357 patients. As other trials have provided new and controversial data, we performed this updated meta-analysis to test the hypothesis. Patients and methods Systematic reviews in Medline, Cochrane, and Science Direct up to December 2015 identified publications exploring the efficacy of PORT in resectable stage IIIA-N2 NSCLC. Re...
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Benefits of respiratory-gated 18F-FDG PET acquisition in lung disease
Background Fluorine-18-fluorodeoxyglucose (18F-FDG) PET/computed tomography (CT) is a reliable imaging modality for the diagnosis of malignant lung nodules and to assess the latter’s prognosis. However, physiological respiratory motion deteriorates PET images and thus decreases the technique’s diagnostic and prognostic values. This issue can be overcome by applying respiratory gating to the 18F-FDG PET/CT acquisitions. Purpose The aim of this study was to evaluate the ability of respiratory-gated 18F-FDG PET/CT to diagnose malignant lung nodules and to predict recurrence and patient survival. Patients and...
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Clinical utility of 18F-FDG PET/CT in low 18F-FDG-avidity breast cancer subtypes: comparison with breast US and MRI
Conclusion PET/CT showed comparable diagnostic performance with US and/or MRI for ALN staging and detecting tumor recurrence even when the primary breast cancer has low 18F-FDG avidity. 18F-FDG PET/CT also detected unsuspected distant metastasis in 36.4% of stage III patients. Surveillance PET/CT should be considered in advanced-stage invasive lobular carcinoma for early detection of recurrence. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Preoperative maximal removal rate of technetium-99m-galactosyl-human serum albumin of the remnant liver is associated with postoperative tumor relapse in hepatitis C virus-related hepatocellular carcinoma
Background Prognosis in patients with hepatocellular carcinoma (HCC) is not only influenced by tumor-related factors but also by the background liver functions. The maximal removal rate of technetium-99m-galactosyl human serum albumin (GSA-Rmax) of the remnant liver (rGSA-Rmax) is a useful candidate for predicting the liver function and clarifying the relationship between the remnant liver functional reserve and tumor-free survival in patients who have undergone hepatectomy. Patients and methods One hundred and sixty-five patients with HCC who underwent curative hepatectomy were divided into three groups of hepatitis ...
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Clinical outcomes and prognostic factors of radioiodine ablation therapy for lymph node metastases from papillary thyroid carcinoma
Conclusion Our data indicate that 131I therapy is highly effective in the treatment of lymph node metastases from papillary thyroid carcinoma; patients with a small size of metastatic lymph node, younger patients, those with lower thyroglobulin levels, and patients with lymph node metastases detectable on the first postablative 131I Rx-WBS and single-photon emission computed tomography–computed tomography showed a good response to radioiodine ablation therapy. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Prognostic factor analysis in 325 patients with Graves’ disease treated with radioiodine therapy
Conclusion Our results showed that 131I treatment was more successful in patients with lower weight of the thyroid, lower free thyroxine level, and shorter ATD taking period. Furthermore, early hypothyroidism after radioiodine treatment was more likely to occur in patients with lower 24-h iodine uptake, lower total dose of iodine, and higher iodine dose per garm of thyroid tissue. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Reproducibility of differential renal function measurement using technetium-99m-ethylenedicysteine dynamic renal scintigraphy: a French prospective multicentre study
Conclusion This prospective multicentre study showed that 99mTc-EC is highly reproducible for assessing DRF in a standard paediatric population, thus validating its use as an alternative to 99mTc-MAG3 in this setting. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Dual time-point quantitative SPECT-CT parathyroid imaging using a single computed tomography: feasibility and operator variability
This study explores the feasibility of co-registering early and delayed SPECT-CT from a single CT and evaluates the most effective combination of images for co-registration. Patients and methods Fourteen retrospective patients with early and delayed planar and SPECT-CT images were recruited for this validation study. Results from contemporaneous early and delayed SPECT-CT, with hardware matched registration, are considered the gold standard. Noncontemporaneous early SPECT with delayed CT and vice versa were also processed with manual alignment by an experienced and a novice operator three times each to evaluate interope...
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Rhenium-188 as a therapeutic radionuclide in low-income and middle-income countries
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2017 Category: Nuclear Medicine Tags: Editorial Source Type: research

Response to: Oral lithium as an adjunctive therapy during radioiodine treatment for hyperthyroidism
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Oral lithium as an adjunctive therapy during radioiodine treatment for hyperthyroidism
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Value of the visual and semiquantitative analysis of carbon-11-methionine PET/CT in brain tumors’ recurrence versus post-therapeutic changes
To compare the visual and semiquantitative analysis of carbon-11-methionine (11C-MET) PET/computed tomography (CT) images in patients with primary brain tumors and suspected recurrence, persistence, or necrotic post-therapeutic changes. A total of 41 consecutive 11C-MET-PET/CT scans on 35 (21 men, mean age 44.1±16.6 years) patients were requested for MRI suspicion of recurrent or persistent primary tumor after therapy. The 11C-MET PET/CT were obtained 20 min after an intravenous injection of 555–740 MBq (15–20 mCi) of 11C-MET. Both visual and semiquantitative evaluations were perform...
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Technical Note Source Type: research

The utility of 18F-FDG PET/CT for the diagnosis of adrenal metastasis in lung cancer: a PRISMA-compliant meta-analysis
Conclusion: 18F-FDG PET/CT plays a vital role in the differentiation of adrenal metastasis from a benign adrenal mass in lung cancer patients, with excellent diagnostic performance. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Common malignant brain tumors: can 18F-FDG PET/CT aid in differentiation?
Conclusion: Central nervous system lymphomas can be differentiated from GBM and metastases by their higher metabolic activity. In addition, 18F-FDG PET/CT can potentially impact therapeutic decisions by detecting primary malignancy in patients with metastatic brain lesions and extracranial disease sites in patients with brain lymphoma. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Clinical relevance of 18F-FDG PET/CT lower-limb imaging in patients with malignant cutaneous melanoma
Conclusion: Our study, the largest of its kind, confirms that, when using 18F-FDG PET/CT for staging, restaging, or surveillance of malignant cutaneous melanoma in patients without previously known or suspected lower-limb melanoma lesions, imaging the lower extremities offers little additional clinically relevant information and stopping the scan at the proximal thighs has essentially no clinical impact. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Comparison of 68Ga-PSMA PET/CT and multiparametric MRI for staging of high-risk prostate cancer68Ga-PSMA PET and MRI in prostate cancer
Conclusion: This study suggests that 68Ga-PSMA PET/CT is useful for lymph node and metastases staging in high-risk prostate cancers, whereas its utility for staging of disease in the prostate is limited. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The efficacy of the available peptide receptor radionuclide therapy for neuroendocrine tumors: a meta-analysis
Conclusion: 90Y-PRRT had the highest disease control rates under both RECIST and SWOG criteria. Tandem-PRRT had the highest disease response rate in the RECIST criteria, indicating that PRRT should be customized to each patient individually for maximum benefit. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Correlation of the apparent diffusion coefficient and the standardized uptake value in neoplastic lesions: a meta-analysis
Conclusion: The two functional parameters of ADC and SUV showed a very weak inverse correlation, which may contribute toward a sophisticated characterization of tumor biology. However, the findings require further validation with trials with large samples and different tumor types. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

A proof-of-concept study analyzing the clinical utility of fluorine-18-sodium fluoride PET-CT in skeletal staging of oncology patients with end-stage renal disease on dialysis
Purpose: The quality of conventional bone scintigraphy can be poor in patients with end-stage renal disease (ESRD). Fluorine-18-sodium fluoride (18F-NaF) PET-computed tomography (CT) has rapid single-pass extraction, fast clearance from the soft tissues and a better target to background ratio. The aim of the present study is to preliminarily assess the superior tracer kinetics of 18F-NaF in ESRD patients. Materials and methods: A cohort comprising of 13 patients with ESRD (mean age 65.5 years; median age 68.5 years; six men and seven women) and a control group of 20 patients with normal renal function (mean age 64±...
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Factors associated with diffusely increased renal uptake of Tc-99m diphosphono-propanedicarboxylic acid on bone scintigraphy in patients with end-stage renal disease
Objective: We aimed to determine the factors contributing toward diffusely increased renal uptake on bone scintigraphy using technetium-99m (Tc-99m) diphosphono-propanedicarboxylic acid (DPD) in patients with end-stage renal disease. Patients and methods: One-hundred and forty-three bone scintigraphies, performed between June 2007 and July 2013, in 135 patients with chronic kidney disease were analyzed retrospectively, including 22 bone scintigraphies (15 patients; eight women; seven men) with glomerular filtration rates less than 15 ml/min/1.73 m2. Patients with nephrocalcinosis were excluded. The clinical ...
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Dynamic risk stratification for predicting the recurrence in differentiated thyroid cancer
Aim: To analyze the predictive value of the dynamic risk stratification (DRS) system for assessing the risk of recurrent/persistent disease in our large group of differentiated thyroid carcinoma (DTC) patients. Patients and methods: We retrospectively included 2184 consecutive patients who received radioiodine ablation therapy following a total or near total thyroidectomy in our department between 1998 and 2014. The American Thyroid Association (ATA) classification was used for initial risk classification. At the second year of follow-up period after radioiodine ablation therapy, DRS was performed also. The ATA and DRS ri...
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Dual-isotope subtraction SPECT-CT in parathyroid localization
Conclusion: Dual-isotope subtraction SPECT-CT imaging has a very high sensitivity and specificity in detecting and locating a parathyroid adenoma, showing that it is a very reliable preoperative imaging technique in primary hyperparathyroidism. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Radioprotective effect of lycopene on the gastrointestinal tract after high-dose radioiodine administration in rat models
Conclusion: As a first study assessing the protective effect of lycopene on gastrointestinal tract organs in a rat model after RAI, these preliminary basic research findings suggest that lycopene appears to exert radioprotective effects against RAI-induced acute gastrointestinal tract damage. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Clinical response to radioactive iodine therapy for prophylactic central neck dissection is not superior to total thyroidectomy alone in cN0 patients with papillary thyroid cancer
Objective: Prophylactic central neck dissection (pCND) is controversial in papillary thyroid carcinoma (PTC) without clinical positive lymph nodes. The aim of this study was to investigate the effect of radioactive iodine (RAI) therapy on the clinical outcome in clinically node-negative (cN0) PTC patients treated with total thyroidectomy (TT) alone or in combination with pCND. Patients and methods: One-hundred and sixty-seven cN0 PTC patients who underwent TT alone (TT) or in combination with pCND (TT+pCND) in our hospital from January 2014 to August 2015 were evaluated retrospectively. Adjuvant RAI therapy was recommende...
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Occipital lobe and posterior cingulate perfusion in the prediction of dementia with Lewy body pathology in a clinical sample
Objective: The aim of this study was to investigate the diagnostic value of occipital lobe and posterior cingulate perfusion in predicting dopamine transporter imaging outcome using a quantitative measure of analysis. Patients and methods: In total, 99 patients with cognitive complaints who had undergone both technetium-99m-hexamethylpropyleneamine oxime single-photon emission computed tomography (99mTc-HMPAO SPECT) and 123I ioflupane (123I-FP-CIT also called DaTSCAN) imaging in a dementia diagnostic center were analyzed. Measures of perfusion were calculated from HMPAO SPECT images for the medial and lateral occipital lo...
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Improving women’s health in low-income and middle-income countries. Part II: the needs of diagnostic imaging
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Editorials Source Type: research

Improving women’s health in low-income and middle-income countries. Part I: challenges and priorities
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 17, 2017 Category: Nuclear Medicine Tags: Editorials Source Type: research

Identification of optimal mask size parameter for noise filtering in 99mTc-methylene diphosphonate bone scintigraphy images
In this study, we have identified the optimal mask size that yields a good smooth bone scan image. Forty four bone scan images were processed using mask sizes 3, 5, 7, 9, 11, 13, and 15 pixels. The input and processed images were reviewed in two steps. In the first step, the images were inspected and the mask sizes that produced images with significant loss of clinical details in comparison with the input image were excluded. In the second step, the image quality of the 40 sets of images (each set had input image, and its corresponding three processed images with 3, 5, and 7-pixel masks) was assessed by two nuclear medicin...
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Technical Note Source Type: research

Coronary fluorine-18-sodium fluoride uptake is increased in healthy adults with an unfavorable cardiovascular risk profile: results from the CAMONA study
This study evaluated the relationship between coronary artery 18F-NaF uptake and cardiovascular risk in healthy adults at low cardiovascular risk. Participants and methods: Study participants underwent blood pressure measurements, blood analyses, and coronary artery 18F-NaF PET/CT imaging. In addition, the 10-year risk for the development of cardiovascular disease, on the basis of the Framingham Risk Score, was estimated. Multivariable linear regression evaluated the dependence of coronary artery 18F-NaF uptake on cardiovascular risk factors. Results: We recruited 89 (47 men, 42 women) healthy adults aged 21–75 yea...
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Reference values for fluorine-18-fluorodeoxyglucose and fluorine-18-sodium fluoride uptake in human arteries: a prospective evaluation of 89 healthy adults
Objective: Reference values of fluorine-18-fluorodeoxyglucose (18F-FDG) and fluorine-18-sodium fluoride (18F-NaF) uptake in human arteries are unknown. The aim of this study was to determine age-specific and sex-specific reference values of arterial 18F-FDG and 18F-NaF uptake. Participants and methods: Uptake of 18F-FDG and 18F-NaF was determined in the ascending aorta, aortic arch, and descending thoracic aorta. In addition, 18F-FDG uptake was determined in the carotid arteries and 18F-NaF uptake was determined in the coronary arteries. Arterial 18F-FDG and 18F-NaF uptake were quantified as the blood pool subtracted maxi...
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Low-dose 90Y PET/CT imaging optimized for lesion detectability and quantitative accuracy: a phantom study to assess the feasibility of pretherapy imaging to plan the therapeutic dose
Conclusion: 90Y PET/CT imaging, even with a low activity concentration, is feasible for depicting the distribution of 90Y implanted microspheres using optimized reconstruction parameters. As such, in-vivo PET/CT imaging of low-dose 90Y in the pretherapeutic stage may be feasible and fruitful to optimally plan the therapeutic activity delivered to patients undergoing radioembolization. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

A clinical evaluation of the impact of the Bayesian penalized likelihood reconstruction algorithm on PET FDG metrics
Purpose: The aim of this study was to evaluate the impact of using the Bayesian penalized likelihood (BPL) algorithm on a bismuth germanium oxide positron emission tomography (PET)/computed tomography (CT) system for 18F-FDG PET/CT exams in case of low injected activity and scan duration. Materials and methods: 18F-FDG respiratory gated PET/CT performed on 102 cancer patients, injected with ∼2 MBq/kg of 18F-FDG, were reconstructed using two algorithms: ordered subset expectation maximization (OSEM) and BPL. The signal-to-noise ratio (SNR) was calculated as the ratio of mean standard uptake value (SUV) over the ...
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

A comparison of 18F-FDG PET/MR with PET/CT in pulmonary tuberculosis
Conclusion: PET/MR visual performance was shown to be comparable to PET/CT in terms of the number of PTB lesions detected. SUVs were significantly lower on PET/MR. Dixon-based attenuation correction underestimates the linear attenuation coefficient of PTB lesions, resulting in lower SUVs compared with PET/CT. However, the use of PET/MR to measure the response of lung lesions to assess response to treatment in research studies is unlikely to be affected by these differences in quantification. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Orbital flourine-18-fluorodeoxyglucose positron emission tomography in patients with Graves’ disease for evaluation of active inflammation
Conclusion: FDG PET/CT may be helpful in detection of extraocular muscle inflammation and it may show ongoing orbitopathy in early stages of inflammation before anatomical changes occur. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The role of 68Ga-PSMA-I&T PET/CT in the pretreatment staging of primary prostate cancer
Conclusion: A role for 68Ga-PSMA-I&T PET/CT in primary PCa staging of high-grade disease (GS 8 or more and PSA>10 ng/ml) has been shown. There was a low rate of detection of PSMA-avid metastases in low-grade disease (GS 7 or less and PSA (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Quantification and reduction of respiratory induced artifacts in positron emission tomography/computed tomography using the time-of-flight technique
Conclusion: Integration of TOF in reconstruction algorithm remarkably improved the white band artifact in the diaphragmatic region. This technique affected the quantification accuracy and resulted in smaller tumor size and higher standardized uptake value in tumors located in/near the diaphragmatic region. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Predictive approaches for post-therapy PET/CT in patients with extranodal natural killer/T-cell lymphoma: a retrospective study
Conclusion: Post-therapy PET/CT analysis using the 5-PS is more able to predict survival than analysis with IHP or [INCREMENT]SUVmax in ENKTL patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Future cardiac events in patients with ischemic ECG changes during adenosine infusion as a myocardial stress agent and normal cardiac scan
Conclusion: Patients with normal myocardial perfusion scintigraphy in whom ST-segment depression develops during adenosine stress test appear to have no increased risk for future cardiac events compared with similar patients without ECG evidence of ischemia. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Comparison of treatment efficacy 1 and 2 years after thyroid remnant ablation with 1110 versus 5550 MBq of iodine-131 in patients with intermediate-risk differentiated thyroid cancer
Conclusion: 1110 MBq of 131I was as effective as 5550 MBq of 131I in the treatment of FCDTC patients with intermediate risk 1 and 2 years after therapy. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

A novel molecular agent for glioma angiogenesis imaging
Conclusion: 18F-FB-endostatin shows promising in-vivo properties. Therefore, the promising properties of 18F-FB-endostatin indicate that this probe can be a powerful tool to evaluate the antiangiogenic therapy for gliomas and thus warrants further investigation as a novel PET probe for imaging of tumor angiogenesis. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

99mTc-exendin(9-39)/octreotide: biokinetics and radiation dosimetry in healthy individuals
Conclusion: All the absorbed doses were comparable to those known for most of the 99mTc studies. 99mTc-exendin(9-39)/octreotide obtained from kit formulations showed high tumor uptake in a patient with a malignant lesion, making it a promising imaging radiopharmaceutical to target GLP-1R and SSTR. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Stress-only myocardial perfusion scintigraphy: a prospective study on the accuracy and observer agreement with quantitative coronary angiography as the gold standard
Conclusion: AC stress-only images yielded a high sensitivity independent of the training level and experience with AC of the nuclear physician, whereas the specificity correlated positively with both. Interobserver and intraobserver agreements tended to be the best for physicians with AC experience. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differentiated thyroid cancer: a randomized-controlled trial
This study aimed to examine the radioprotective effect of vitamin E on salivary glands after radioactive iodine (131I) therapy in patients with differentiated thyroid cancer. Patients and methods: Eighty-two patients with differentiated thyroid cancer were enrolled in this study. They were divided randomly into four groups (control group: 22 cases, group A: 23 cases, group B: 22 cases, and group C: 15 cases) before postsurgical ablation therapy with 100 mCi 131I. The patients in groups A, B, and C received vitamin E 100, 200, and 300 mg/day orally, respectively, for a duration of 1 week before to 4 weeks aft...
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Diagnostic value of 99mTc-ubiquicidin scintigraphy in differentiation between osteomyelitis and bone tumors
Conclusion: Although 99mTc-UBI scintigraphy in the dynamic imaging format was very useful with high accuracy in differentiating between infectious and tumoral lesions, it was not useful to distinguish these two entities on the basis of visual assessment or T/NT ratio measurement on static images. The study also showed the high accuracy of this noninvasive modality in acute osteomyelitis with low diagnostic value in chronic infectious processes. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - October 20, 2017 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Brown adipose tissue detected by PET/CT imaging is associated with less central obesity: Erratum
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - September 14, 2017 Category: Nuclear Medicine Tags: Erratum Source Type: research