Harmonization of standardized uptake values between two scanners, considering repeatability and magnitude of the values in clinical fluorine-18-fluorodeoxyglucose PET settings: a phantom study: Erratum
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Erratum Source Type: research

Calculation of interobserver agreement in Ga68 PSMA-PET/CT: weighted kappa
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Agreement for the interpretation of 68Ga-prostate-specific membrane antigen-I&T positron emission tomography/computed tomography imaging; methodological issues to avoid misinterpretation
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Brain glucose metabolism in patients with newly diagnosed multiple myeloma significantly decreases after high-dose chemotherapy followed by autologous stem cell transplantation
Conclusion Multiple myeloma patients who received HDC/ASCT demonstrated a significant decrease in 18FDG uptake in the supratentorial brain and cerebellum, while patients who received CDC did not demonstrate significant changes in the brain 18FDG uptake. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The early prediction of pathological response to neoadjuvant chemotherapy and prognosis: comparison of PET Response Criteria in Solid Tumors and European Organization for Research and Treatment of Cancer criteria in breast cancer
Conclusion EORTC criteria and PERCIST had early predictive value to long-term outcome, but moderate value for pCR. Furthermore, PERCIST might show more potential than the EORTC criteria and conventional PET-based parameters to predict prognosis in breast cancer patients following two cycles of neoadjuvant chemotherapy. Video abstract: see http://links.lww.com/NMC/A162. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Diagnostic performance of 18F-2-fluoro-2-deoxy-D-glucose PET/computerized tomography in identifying bone marrow infiltration in new patients with diffuse large B-cell lymphoma and Hodgkin lymphoma
Conclusion 18F-FDG PET/CT seemed to be an excellent diagnostic test in assessment of BMI at initial assessment and staging of Hodgkin lymphoma and DLBCL patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The association of 18F-fluorodeoxyglucose PET/computed tomography parameters with tissue gastrin-releasing peptide receptor and integrin αvβ3 receptor levels in patients with breast cancer
Conclusion GRPR and integrin αvβ3 expression results are complementary to 18F-FDG PET/CT findings, and are also significantly correlated with hormone receptors associated with aggressive subtypes. These results may pave the way for GRPR and integrin αvβ3 targeted imaging with 68Ga-labeled molecules and systemic radionuclide treatment with 177Lu-labeled compounds. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Correlation of PD-L1 expression on tumor cell and tumor infiltrating immune cell with 18F-fluorodeoxyglucose uptake on PET/computed tomography in surgically resected pulmonary adenocarcinoma
Conclusion High SUVmax is associated with PD-L1 expression on TC and IC in surgically resected pulmonary ADC. 18F-FDG-PET/CT imaging can be a potential tool to evaluate PD-L1 expression in pulmonary ADC. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Robotic-assisted computed tomography-guided 18F-FDG PET/computed tomography-directed biopsy for diagnosis of intra thoracic lesions: An experience from a tertiary care centre in North India.
Conclusion Robotic-assisted CT-guided 18F-FDG PET/CT-directed biopsy is a useful and accurate technique for diagnostic evaluation of intrathoracic neoplasms with minimal complications rates as compared with conventional imaging techniques. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

PET/computed tomography shows association between subjective pain in knee joints and fluorine-18-fluorodeoxyglucose uptake
Objective The aim of this study was to evaluate the capability of fluorine-18-fluorodeoxyglucose (18F-FDG)-PET/computed tomography (CT) in screening for musculoskeletal inflammation and injury in the knee region. Methods The study included 12 subjects (6 men and 6 women) who complained of knee pain at rest and 94 controls who did not. Maximum standardized uptake value (SUV)max was calculated for the right and left knees and compared via a 4-point numerical rating scale (NRS) for subjective knee pain. Correlations between SUV values were also evaluated. Results SUVmax was significantly higher in knee joints with res...
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Interobserver agreement of the visual Herder scale for the assessment of solitary pulmonary nodules on 18F Fluorodeoxyglucose PET/computed tomography
Conclusion Our study suggests excellent interobserver agreement for use of the Herder scale in evaluating SPNs. Reviewer confidence scores were high reflecting high confidence in the use of the Herder scale for evaluating SPN. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Outcome of radioiodine therapy in thyroid cancer patients with recent contrasted computed tomography
Conclusion RIT in postthyroidectomy setting can be successfully performed within 90 days after CCT. Further research is needed to confirm our findings. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Comparison of 99mTc-DTPA and serum creatinine, cystatin C in detection of glomerular filtration rate: a retrospective clinical data analysis of 744 Chinese subjects
Conclusion Our data suggest that estimating glomerular filtration rate equations evaluated by serum cystatin C were better than serum creatinine-based equations, estimating glomerular filtration rate equations evaluated by both serum creatinine and cystatin C were better than those evaluated by serum creatinine or cystatin C alone. Among all enrolled equations, Fengscr-cys equation might be the best one to evaluate glomerular filtration rate in general Chinese paticipants. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The success rate of radioactive iodine therapy for Graves’ disease in iodine-replete area and affecting factors: a single-center study
Objective Initial treatment options for Graves’ disease include antithyroid drugs, radioactive iodine (RAI), and surgery. Because of similar effects of three modalities, initial treatment preferences differ by country to country. In Korea, iodine-replete area, RAI was used as a second-line option. For these reasons, the RAI success rate in Korea might differ from other countries. Methods A total of 247 patients were enrolled. The primary outcome was cumulative success rate in the first year, and the secondary outcome was factors that affected the success. Delayed response, which included patients who attained su...
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Myocardial perfusion abnormalities in Eisenmenger syndrome
Conclusion Myocardial perfusion defects, both in RV and LV, occur even in asymptomatic or mildly symptomatic patients with Eisenmenger syndrome. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Study of novel deformable image registration in myocardial perfusion single-photon emission computed tomography
Objective In the present study, deformable image registration (DIR) technology was applied to gated myocardial perfusion single-photon emission computed tomography (G-MPS) reconstructed images in distorting all image phases. We aimed to define a new method of end-diastole compatible image registration and verify the clinical usability for any cardiac volume. Methods Projection images were created using the Monte Carlo simulation. All image phases were shifted to fit the end-diastole phase by applying DIR to images that were reconstructed from projection images. Defect ratios were subsequently evaluated using the simul...
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The value of 18F-FDG PET-CT and 131I-norcholesterol scintigraphy in the characterization of high-risk adrenal masses
Conclusion Conventional CT and FDG PET parameters are not adequately specific for determination of a benign lesion in this selected cohort of high-risk patients. Use of 131I-norcholesterol in this patient cohort may provide additional value. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Single-photon emission computed tomography/computed tomography arthrography of wrist, ankle, and knee joints
Conclusion The addition of arthrography to single-photon emission computed tomography/computed tomography of wrist, ankle, and knee joints leads to supplementary visibility of lesions of cartilage, ligaments, triangular fibrocartilage complex, meniscus, or loose bodies in 77% of joints. Single-photon emission computed tomography/computed tomography arthrography can serve as promising alternative especially in patients with magnetic resonance imaging contraindications or metallic hardware. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Thank you to the top reviewers of Nuclear Medicine Communications in 2019
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - February 19, 2020 Category: Nuclear Medicine Tags: Editorial Source Type: research

[18F] FBB cortical uptake is not related to the age of onset of Alzheimer’s disease
Conclusion In our study group, the age of onset is not related to brain amyloid burden in Alzheimer’s disease patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

The impact of Ga-68 DOTATATE PET/CT imaging on management of patients with paragangliomas
Conclusion Ga-68 DOTATATE PET/CT findings led to a change in the scheduled treatment plan in 90.9% of patients with suspected recurrence. The most frequent change consisted in initiation of PRRT due to disease recurrence or progression or detection of multiple metastases. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

18F-FDG-PET/CT in measuring volume and global metabolic activity of thigh muscles: a novel CT-based tissue segmentation methodology
We present a novel computed tomography-based tissue segmentation methodology for determining volume and global uptake of FDG of the thigh muscles and correlate these parameters with age. Materials and methods A total of 71 subjects from a prospective clinical trial (NCT01724749) were included. PET/CT scans were acquired 180 minutes after intravenous injection of FDG. A 3D growing region algorithm with neighborhood Hounsfield unit threshold between one and 150 was used to highlight the muscle. FDG uptake was expressed as the average mean standardized uptake value normalized for lean body mass (average SULmean). Femur vol...
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Positron emission tomography/magnetic resonance imaging for the diagnosis and differentiation of pancreatic tumors
Conclusion The integration of PET/MR imaging could be used to efficiently diagnose whether the pancreatic tumor was benign or malignant. The SUVmax/ADC was the most efficient metric, while it could not help in the differentiation of pancreatic cancer. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Qualitative and quantitative reproducibility of [18]fluoromethycholine PET/computed tomography in prostate cancer
Conclusion Our study demonstrated that visual report of [18F]FCH PET/CT was very reproducible and that the repeatability limits of SUVmax was similar to those of other PET radiotracers. An SUVmax difference of more than 40% should be considered as representing a treatment response effect. Change of SUVmax during the acquisition time varied and should not be considered as an interpretation criterion. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

In primary lymph nodal staging of patients with high-risk and intermediate-risk prostate cancer, how critical is the role of Gallium-68 prostate-specific membrane antigen positron emission tomography-computed tomography?
Conclusion 68Ga-PSMA PET-CT allows accurate detection of lymphnodal metastases in patients with intermediate-risk and high-risk prostate cancer prior to definitive surgical treatment. It performed better than mp-MRI in a subset of patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

13N-ammonia PET/CT stress myocardial blood flow compared to fractional flow reserve in coronary artery disease
Conclusion Discordance with stress myocardial blood flow in the corresponding flow territory was found in 32% of the fractional flow reserve-measurements. Patients with reduced stress myocardial blood flow but normal fractional flow reserve showed significantly reduced stress myocardial blood flow in all coronaries and a trend towards more cardiac adverse events. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Renal artery wall 18F-NaF activity and glomerular filtration rate: an exploratory analysis in a high cardiovascular risk population
Objectives Atherosclerotic plaque molecular imaging with 18F-sodium fluoride (NaF) PET with computed tomography (PET-CT) may identify active unstable microcalcification. We sought to explore renal arteries calcification activity in a group of high cardiovascular (CV) risk subjects without manifest CV disease. Methods High CV risk hypertensive individuals from a single centre were prospectively scanned with 18F-NaF-PET-CT in major vascular territories. Renal arterial wall activity was retrospectively analysed and expressed as the ratio between maximum standard uptake value in the lesion and mean blood pool activity in ...
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Role of gamma probe-assisted intraoperative sentinel lymph node evaluation in predicting axillary breast cancer metastasis after neoadjuvant chemotherapy
Conclusions Sentinel lymph node identification using preoperative scintigraphy and intraoperative use of gamma probe seems to be a feasible and efficient method in terms of differentiating patients that require axillary lymph node dissection during breast cancer surgery, even when they have received neoadjuvant chemotherapy. Further large prospective studies allowing subgroup analyses are warranted. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

A microdosimetry model of kidney by GATE Monte Carlo simulation using a nonuniform activity distribution in digital phantom of nephron
Conclusion Average dose of nephron is not a reliable parameter for nephrotoxicity evaluation. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

99mTc-D(RGD): molecular imaging probe for diagnosis of α: v: β: 3: -positive tumors
Conclusion The novel 99mTc HYNIC- D(RGD) was demonstrated to be a useful radiotracer for the assessment of αvβ3-positive tumor in animal model. Therefore, further clinical and preclinical studies are required. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Interobserver reproducibility of mercaptoacetyltriglicine renography in children and adults with suspected obstruction: parameters of drainage and function calculated by International Atomic Energy Agency software
Conclusion Our results indicate an excellent interobserver reproducibility for all quantitative parameters of IAEA software in both pediatric and adult patients. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Use of pinhole dual-phase Tc-99m sestamibi vs combined Tc-99m sestamibi and Tc-99m pertechnetate scintigraphy in patients with hyperparathyroidism where single-photon emission computed tomography/computed tomography is unavailable
Conclusion Pinhole dual-phase Tc-99m sestamibi alone has high accuracy in the detection of PA. The routine addition of Tc-99m pertechnetate to Tc-99m sestamibi does not result in significant improvement in the detection of PA or PH and should be reserved for equivocal cases. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - January 16, 2020 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Prognostic value of neutrophil-to-lymphocyte ratio and its correlation with fluorine-18-fluorodeoxyglucose metabolic parameters in intrahepatic cholangiocarcinoma submitted to 90Y-radioembolization
Conclusion NLR is correlated with SUVmax-mean values in ICC and resulted to be an easy available predictor of survival in patients submitted to treatment with 90Y-microspheres. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Analysis of prognostic factors in patients receiving transarterial radioembolization for unresectable hepatocellular carcinoma
Conclusion Patients with low basal albumin-bilirubin grade and neutrophil-lymphocyte ratio survive longer after transarterial radioembolization for unresectable hepatocellular carcinoma. Presence of extrahepatic metastases and portal venous thrombosis seems to have a prognostic value. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Prospective evaluation of phosphorus-32 radiation synovectomy in patients with severe and chronic rheumatoid arthritis unresponsive to conventional medical treatment
Objectives To determine the efficacy of Phosphorus-32 radiation synovectomy in the treatment of patients with severe rheumatoid arthritis (RA) unresponsive to systematic or local medical therapy. Methods Twenty-three knees in 16 patients with severe chronic RA were prospectively treated by intra-articular installation of Phosphorus-32 and evaluated at 1, 3, 6, and 12 months. The Western Ontario and McMaster Universities Arthritis index (WOMAC), visual analog scale (VAS), Health Assessment Questionnaire (HAQ), pain scale, and grade of joint effusion and tenderness were assessed. At the 12-month time interval, the treat...
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Clinical implication of 18F-NaF PET/computed tomography indexes of aortic calcification in coronary artery disease patients: correlations with cardiovascular risk factors
In this study, correlations between 18F-NaF PET/computed tomography (CT) findings and cardiovascular risk factors were investigated in patients with suspected coronary artery disease. Patients and methods Forty patients with suspected coronary artery disease underwent 18F-NaF PET/CT. The maximum and overall burden of calcifying activity, and the overall burden of calcium deposition in the descending thoracic aorta (DTA) were measured on 18F-NaF PET/CT and they were compared with cardiovascular risk factors, particularly, with those related to metabolic syndrome. Results The maximum and overall burden of calcifying ac...
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Prognostic value of dual-point fluorine-18 fluorodeoxyglucose PET imaging, partial volume correction and glucose transporter-1 expression in resected nonsmall cell lung cancer patients.
Objective To investigate the relationship between the prognosis and glucose transporter-1 (Glut-1) expression or fluorine-18 fluorodeoxyglucose uptake using partial volume correction and dual-point imaging in surgically resected nonsmall cell lung cancer (NSCLC) patients. Methods Our patient population consisted of 108 NSCLC cases. The early maximum standardized uptake value (ESUVmax), delayed SUVmax (DSUVmax), partial volume correction SUVmax (cSUVmax) and retention index of primary lesions were calculated. Cox proportional hazard model was applied to evaluate the effects of PET parameters and Glut-1 expression. Over...
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Sequential PET/diffusion-weighted imaging in the evaluation of myocardial perfusion and viability in coronary artery disease: a preliminary study
Objectives To evaluate the utility of sequential F-18 fluorodeoxyglucose PET/diffusion-weighted imaging in assessing myocardial perfusion and viability in coronary artery disease. Methods Fourteen coronary artery disease patients and five non-coronary artery disease subjects underwent sequential cardiac F-18 fluorodeoxyglucose PET/diffusion-weighted imaging using a trimodality PET/computed tomography-MRI system. The perfusion data were acquired by measuring low b-values apparent diffusion coefficient using diffusion-weighted imaging. Regional myocardial viability was determined by perfusion/metabolism patterns. The pe...
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Impact of 18F-fluorodeoxyglucose PET/CT in the management of patients with plasma cell disorders
Conclusion PET/CT resulted in a change in planned management in more than two-thirds of patients with plasma cell disorders in the current selected patient cohort. These results should be validated in a larger prospective trial. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Preliminary clinical assessment of dynamic 18F-fluorodeoxyglucose positron-emission tomography/computed tomography for evaluating the clinicopathological grade in patients with non-Hodgkin’s lymphoma: a prospective study
Conclusion The dynamic second and third phase could potentially provide good predictors of clinicopathological discrimination, as can the early and delayed phases. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Revalidation of PET/computed tomography criteria (Hopkins criteria) for the assessment of therapeutic response in lung cancer patients: inter-reader reliability, accuracy and survival outcomes
Conclusion The use of Hopkins criteria for posttherapy assessment in patients with lung cancer represents an easy and reproducible method with substantial to almost perfect interobserver agreement and high positive predictive value and accuracy; moreover, it is easily understood by referring physicians. Additionally, there was no significant difference when applying a semi-quantitative measure to the same five-point score. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Compatibility of [99mTc]Tc-EDDA/HYNIC-TOC and [68Ga] Ga-DOTA-TOC in a syringe for intravenous administration
Objective Drug quality in medical devices is not evaluated during the marketing authorization of radiopharmaceuticals. Therefore, the extemporaneous change of packaging made for preparation of patient unit doses in a syringe is the responsibility of radiopharmacists. The present study aimed to determine the impact of packaging and storage in a polypropylene syringe on the quality of hydrophilic drugs [99mTc]Tc-EDDA/HYNIC-TOC (Tektrotyd) and [68Ga]Ga-DOTA-TOC (Somakit-TOC). Methods Appearance, pH, radiochemical purity, sterility, and endotoxin tests were performed according the current European Pharmacopoeia. Subvisibl...
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Predicting large-volume lymph node metastasis in the clinically node-negative papillary thyroid microcarcinoma: a retrospective study
This study aimed to determine clinical predictors for large-volume LNM in clinically node-negative PTMC. Methods A total of 947 clinically N0 PTMC patients who received total thyroidectomy with lymph node dissection and radioiodine therapy were included. Based on the LNM status, they were divided into two groups: large-volume LNM and small-volume LNM including those patients without LNM. The association between age, gender and other clinical factors and large-volume LNM were investigated. The recurrence-free survival was also compared among these groups. Results We found that male gender [odds ratio (OR) =&thi...
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Sub-segmentation specific paradigms for better individualized management of poorly differentiated thyroid carcinoma: can a systematic approach be evolved?
No abstract available (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - December 6, 2019 Category: Nuclear Medicine Tags: Editorial Source Type: research

Direct bilirubin level is an independent risk factor for atrial fibrillation in thyrotoxic patients receiving radioactive iodine therapy
This study aimed to indicate the risk factors of atrial fibrillation (AF) in thyrotoxic patients receiving radioactive iodine (RAI) therapy after antithyroid drug and other medication. Methods This study was a retrospective cohort study. Thyrotoxic patients were divided into two groups, with or without AF. Clinical features were retrospectively analyzed. Univariate and multivariate analyses of data from thyrotoxic patients were performed to evaluate the probability of AF. Results The following clinical factors were found to be correlated with AF: age, gender, duration of hyperthyroidism, coronary artery disease, hype...
Source: Nuclear Medicine Communications - November 16, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

68Ga-prostate-specific membrane antigen PETCT-based response to androgen deprivation therapy in patients with prostate cancer
Conclusion Primary prostatic tumor seems less likely to respond to ADT than nodal or metastatic lesions. Residual primary uptake may guide patient selection for local therapy in (oligo) metastatic prostate cancer. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 16, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Metabolic imaging patterns in posterior cortical atrophy and Lewy body dementia
Conclusion [18F]FDG PET may be useful as a non-invasive diagnostic modality in differentiating the two posterior cortical dementias, despite significant overlap. Primary visual cortical hypometabolism can serve as an independent diagnostic marker for DLB, even in the absence of TRODAT imaging. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 16, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

18F-Flourodeoxy glucose PET–computed tomography in testicular carcinoma: diagnostic and prognostic value
Conclusion In this single-center experience with a limited number of patients, 18F-FDG PET/computed tomography appears to have a value of staging and restaging for both seminomatous and non-seminomatous GCTs. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 16, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

18F-choline positron emission tomography/computed tomography for the detection of prostate cancer relapse: assessment of maximum standardized uptake value correlation with prostate-specific antigen levels
Objective Patients with prostate cancer are monitored by prostate-specific antigen (PSA) evaluation and PET [PET/computed tomography (CT)]. The aim of our study was to evaluate correlations between PSA levels and standardized uptake values (SUV) in patients with recurrent prostate cancer. Methods We analyzed 282 prostate cancer patients undergoing PET-CT due to suspicion of recurrence. Levels of PSA and PSA change per month were analyzed, together with maximum standardized uptake value (SUVmax). Results PET/CT results were positive in 175 patients (62.1%) and negative in 107 patients (37.9%). In the positive group,...
Source: Nuclear Medicine Communications - November 16, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research

A simple prediction model using fluorodeoxyglucose-PET and high-resolution computed tomography for discrimination of invasive adenocarcinomas among solitary pulmonary ground-glass opacity nodules
Conclusion Using HRCT combined with FDG-PET to establish the corresponding mathematical prediction model has the potential to identify IVA in early lung adenocarcinoma preoperatively. (Source: Nuclear Medicine Communications)
Source: Nuclear Medicine Communications - November 16, 2019 Category: Nuclear Medicine Tags: Original Articles Source Type: research