Reply to ‘Use of convalescent plasma in the treatment of COVID-19’
Nature Reviews Nephrology, Published online: 17 February 2023; doi:10.1038/s41581-023-00691-3Reply to ‘Use of convalescent plasma in the treatment of COVID-19’ (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - February 17, 2023 Category: Urology & Nephrology Authors: Naoka Murakami Robert Hayden Thomas Hills Hanny Al-Samkari Jonathan Casey Lorenzo Del Sorbo Patrick R. Lawler Meghan Sise David E. Leaf Source Type: research

Bridging the gap of referral to nephrology care
Nature Reviews Nephrology, Published online: 17 February 2023; doi:10.1038/s41581-023-00693-1Optimal referral of patients who are at risk of kidney failure to nephrologists could improve their long-term outcomes. Various strategies, including the inclusion of kidney failure risk equations in electronic medical records and the active dissemination of clinical practice guidelines, could help to reduce the gap between optimal referral and what currently happens in clinical practice. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - February 17, 2023 Category: Urology & Nephrology Authors: Nestor Oliva-Damaso Navdeep Tangri Pierre Delanaye Richard J. Glassock Source Type: research

Disaster preparedness for patients with kidney disease
Nature Reviews Nephrology, Published online: 06 February 2023; doi:10.1038/s41581-023-00678-0Access to essential medical care can be compromised by social disruptions (such as riots and labour strikes), armed conflict and natural disasters, including extreme weather events. A successful response to such events requires forward planning, preparation and rehearsal with involvement of health-care systems, professionals, patients and their support networks. Following execution of the response, after-action evaluation is required to improve future responses. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - February 6, 2023 Category: Urology & Nephrology Authors: Jeffrey B. Kopp Kenneth Lempert Kristen Finne Source Type: research

Author Correction: Therapeutic advances in COVID-19
Nature Reviews Nephrology, Published online: 06 February 2023; doi:10.1038/s41581-023-00686-0Author Correction: Therapeutic advances in COVID-19 (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - February 6, 2023 Category: Urology & Nephrology Authors: Naoka Murakami Robert Hayden Thomas Hills Hanny Al-Samkari Jonathan Casey Lorenzo Del Sorbo Patrick R. Lawler Meghan E. Sise David E. Leaf Source Type: research

Fasting induces structural and functional changes in the peritoneal membrane
Nature Reviews Nephrology, Published online: 31 January 2023; doi:10.1038/s41581-023-00688-yFasting induces structural and functional changes in the peritoneal membrane (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 31, 2023 Category: Urology & Nephrology Authors: Ellen F. Carney Source Type: research

Pathological consequences of DNA damage in the kidney
Nature Reviews Nephrology, Published online: 26 January 2023; doi:10.1038/s41581-022-00671-zThe DNA damage response is essential to genomic stability. Here, the authors discuss DNA damage-induced nephrotoxicity and kidney cancer, and the essential role of DNA repair in kidney homeostasis, as well as its potential to contribute to kidney dysfunction, including the links between DNA damage, cell-cycle control and ciliopathies. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 26, 2023 Category: Urology & Nephrology Authors: Juan I. Garaycoechea Catherine Quinlan Martijn S. Luijsterburg Source Type: research

VPS34 functions in the proximal tubule
Nature Reviews Nephrology, Published online: 24 January 2023; doi:10.1038/s41581-023-00685-1VPS34 functions in the proximal tubule (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 24, 2023 Category: Urology & Nephrology Authors: Susan J. Allison Source Type: research

Targeting glutamine use in RCC
Nature Reviews Nephrology, Published online: 24 January 2023; doi:10.1038/s41581-023-00684-2Targeting glutamine use in RCC (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 24, 2023 Category: Urology & Nephrology Authors: Monica Wang Source Type: research

Heat and health inequity: acting on determinants of health to promote heat justice
Nature Reviews Nephrology, Published online: 20 January 2023; doi:10.1038/s41581-023-00679-zClimate change is increasing global temperatures and causing more frequent and severe extreme heat events. The resulting additional disease burden is inequitably distributed. Strategies that reduce inequities in heat exposure and vulnerability to heat-related illness, as well as health protections at multiple levels (from individual to regional), are urgently needed to contain the looming crisis. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 20, 2023 Category: Urology & Nephrology Authors: Jeremy Hess Source Type: research

Environmental pollution, heat stress and kidney health: a need for integrated assessment
Nature Reviews Nephrology, Published online: 20 January 2023; doi:10.1038/s41581-023-00680-6Thousands of environmental chemicals are used globally. However, despite clear evidence of their adverse effects on the kidney, substantial knowledge gaps remain. Further studies are needed to better understand the effects of chemical mixtures, windows of physiological susceptibility, vulnerable populations, and the intersection of chemical exposure with health risks associated with climate change and heat stress. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 20, 2023 Category: Urology & Nephrology Authors: Alison P. Sanders Nishad Jayasundara Source Type: research

Climate change-fuelled natural disasters and chronic kidney disease: a call for action
Nature Reviews Nephrology, Published online: 20 January 2023; doi:10.1038/s41581-023-00682-4People with kidney disease are particularly vulnerable to the impacts of natural disasters and extreme weather events. As climate change is increasing the frequency and severity of these events, a robust response is needed to improve disaster preparedness and increase the resilience of these patients. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 20, 2023 Category: Urology & Nephrology Authors: Amir Sapkota Peter Kotanko Source Type: research

Consequences of famine and malnourishment on kidney health
Nature Reviews Nephrology, Published online: 19 January 2023; doi:10.1038/s41581-023-00681-5Adequate nutrition is essential for kidney health; however, attempts to improve nutrition and food security have been hindered in recent years by man-made and natural disasters. Approaches to eradicate famine, improve nutritional status and reduce food insecurity are needed to reduce inequities and maintain kidney health in the face of adverse circumstances. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 19, 2023 Category: Urology & Nephrology Authors: Gerjan Navis Source Type: research

Hope for resistant hypertension through BrigHTN and PRECISION
Nature Reviews Nephrology, Published online: 19 January 2023; doi:10.1038/s41581-023-00676-2An estimated 10–15% of individuals with hypertension are resistant to available antihypertensive therapies. Findings from two new clinical trials — BrigHTN and PRECISION — that assessed the blood pressure-lowering effects of the aldosterone synthase inhibitor baxdrostat and the dual endothelin receptor antagonist aprocitentan, respectively, suggest these approaches hold promise for patients with treatment-resistant hypertension. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 19, 2023 Category: Urology & Nephrology Authors: R. M. Touyz D. G. Harrison Source Type: research

Informing clinical decision making during a pandemic — a call for better preparedness
Nature Reviews Nephrology, Published online: 18 January 2023; doi:10.1038/s41581-023-00677-1The COVID-19 pandemic exposed flaws in the ability of the nephrology community to efficiently inform clinical decision making. To improve preparedness for the next pandemic, the nephrology community must work more closely together to ensure that research efforts are aligned and put in place a strategy for the effective dissemination of high-quality evidence in real-time. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 18, 2023 Category: Urology & Nephrology Authors: Priya Vart Luuk B. Hilbrands Ron T. Gansevoort Source Type: research

Exercise and chronic kidney disease: potential mechanisms underlying the physiological benefits
Nature Reviews Nephrology, Published online: 17 January 2023; doi:10.1038/s41581-022-00675-9This Review discusses the potential mechanisms by which regular exercise has beneficial effects on chronic inflammation, cardiovascular health, lipid metabolism, insulin resistance, sarcopenia and bone health in people with kidney disease. The authors highlight areas for further investigation to enhance the benefits of exercise for this population. (Source: Nature Reviews Nephrology)
Source: Nature Reviews Nephrology - January 17, 2023 Category: Urology & Nephrology Authors: Nicolette C. Bishop James O. Burton Matthew P. M. Graham-Brown David J. Stensel Jo ão L. Viana Emma L. Watson Source Type: research