Pathological consequences of DNA damage in the kidney

Nature Reviews Nephrology, Published online: 26 January 2023; doi:10.1038/s41581-022-00671-zThe DNA damage response is essential to genomic stability. Here, the authors discuss DNA damage-induced nephrotoxicity and kidney cancer, and the essential role of DNA repair in kidney homeostasis, as well as its potential to contribute to kidney dysfunction, including the links between DNA damage, cell-cycle control and ciliopathies.

Source: Nature Reviews Nephrology - January 26, 2023 Category: Urology & Nephrology Authors: Juan I. Garaycoechea Catherine Quinlan Martijn S. Luijsterburg Source Type: research