Immunotherapy Plus Targeted Drug in First-line Kidney Cancer Immunotherapy Plus Targeted Drug in First-line Kidney Cancer
First-line immunotherapy with avelumab plus axitinib significantly improves progression-free survival in advanced kidney cancer over sunitinib, with no additional safety issues.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 22, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

High-dose, high-precision radiation therapy safe, effective for solitary kidney cancer patients with only one kidney
(American Society for Radiation Oncology) Treatment of renal cell carcinoma with stereotactic radiation therapy is as safe and effective for patients with one kidney as it is for those who have two, according to an analysis of the largest-ever, international dataset of solitary kidney patients to receive this emerging treatment. Findings will be presented in a news briefing today at 12 p.m. from the American Society for Radiation Oncology (ASTRO) Annual Meeting. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 22, 2018 Category: Cancer & Oncology Source Type: news

Merck, Pfizer combo treatment meets main goals of kidney cancer trial
Merck& Co said on Thursday a combination treatment of its cancer drug Keytruda and Pfizer Inc's Inlyta met the main goals of a late-stage study in patients with the most common form of kidney cancer. (Source: Reuters: Health)
Source: Reuters: Health - October 18, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

LoginSearchLATEST A look ahead to key trial readouts at ESMO
ESMO is only 7 days away. Here is an inside look at some of the trials that will be discussed.10/12/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 12, 2018 Category: Urology & Nephrology Source Type: news

8 Surprising Health Benefits of Wakame Seaweed
Wakame seaweed may have cancer-fighting properties. A study found that specific compounds extracted from the seaweed were effective at inhibiting the growth of colon and kidney cancer cells.10/12/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 12, 2018 Category: Urology & Nephrology Source Type: news

' Revolutionary' Data to Be Presented at ESMO 2018'Revolutionary' Data to Be Presented at ESMO 2018
Evolutions and even revolutions are expected when the latest data in head and neck cancer, renal cell carcinoma, breast cancer, and ovarian cancer are presented at the leading European cancer meeting.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 11, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Cabozantinib to Be Featured in 13 Presentations at ESMO 2018 Congress
Cabozantinib will be the subject of 13 presentations at the European Society for Medical Oncology (ESMO) 2018 Congress, which is being held October 19-23, 2018 in Munich, Germany.10/09/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 9, 2018 Category: Urology & Nephrology Source Type: news

Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC): A Contemporary Review and Practical Discussion of the Differential Diagnosis for HLRCC-Associated Renal Cell Carcinoma
Hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC) is an uncommon disorder with germline-inactivating mutations in the fumarate hydratase ( FH) gene. The kidney cancers that develop in patients with HLRCC are often unilateral and solitary, with a potentially aggressive clinical course; morphologic identification of suspicious cases is of the utmost importance.10/08/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 8, 2018 Category: Urology & Nephrology Source Type: news

Kidney cancer symptoms: Warning signs of the deadly disease could be confused with this
KIDNEY cancer symptoms are not always obvious in the early stages of the disease, and when they do occur, after often similar to those of less serious conditions. Here ’s what to look out for and when you should see a doctor. (Source: Daily Express - Health)
Source: Daily Express - Health - October 7, 2018 Category: Consumer Health News Source Type: news

Kidney cancer symptoms: Blood in your urine could be a sign of the disease
KIDNEY cancer symptoms are not often obvious at first and can be confused with other, less serious conditions. But if symptoms do occur, blood in urine could be a sign. (Source: Daily Express - Health)
Source: Daily Express - Health - October 6, 2018 Category: Consumer Health News Source Type: news

Kidney cancer symptoms: Noticing blood here could indicate the deadly disease
KIDNEY cancer symptoms are not often obvious at first and can be confused with other, less serious conditions. But if symptoms do occur, noticing blood here could be a sign. (Source: Daily Express - Health)
Source: Daily Express - Health - October 6, 2018 Category: Consumer Health News Source Type: news

Kidney cancer symptoms: Should you see a doctor if you notice blood in your urine?
KIDNEY cancer symptoms are not often obvious at first and can be confused with other, less serious conditions. But if symptoms do occur, noticing blood in your urine could be a sign. But should you see a doctor, even if it's a one-off or just a tiny amount? (Source: Daily Express - Health)
Source: Daily Express - Health - October 6, 2018 Category: Consumer Health News Source Type: news

No link between progression-free survival, quality of life in cancer trials
In clinical trials evaluating cancer interventions, there was no significant association between progression-free survival and health-related quality of life, according to research published in JAMA Internal Medicine.10/05/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 5, 2018 Category: Urology & Nephrology Source Type: news

Differentiating Benign Renal Tumors From Chromophobe RCC
A radiographic measure may help clinicians distinguish between benign renal oncocytoma and chromophobe renal cell carcinoma. (Source: CancerNetwork)
Source: CancerNetwork - October 4, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Robotic Tumor Enucleation Appears Safe for Sporadic Renal Cell Carcinoma
The use of robotic tumor enucleation conferred favorable long-term surgical margins and local recurrence rates in patients with sporadic renal cell carcinoma (RCC), according to the results of a single-center Italian study.10/04/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 4, 2018 Category: Urology & Nephrology Source Type: news

A New Front Line Is Taking Shape in Metastatic Renal Cell Carcinoma
The dismal prognosis for patients with metastatic renal cell carcinoma (mRCC) has fueled an earnest quest for more effective treatments, culminating in a better understanding of the disease and regulatory approval of several new drugs and therapeutic combinations.10/04/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 4, 2018 Category: Urology & Nephrology Source Type: news

What Makes the Nobel-Winning Breakthroughs in Immunotherapy So Revolutionary Read more: https://www.smithsonianmag.com/science-nature/nobel-winning-breakthroughs-in-immunotherapy-revolutionary-1809704
This article by Smithsonian Magazine explains the importance of this approach in treating cancer.10/04/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 4, 2018 Category: Urology & Nephrology Source Type: news

Epidemiology of Renal Cell Carcinoma
Smoking, obesity, hypertension and chronic kidney disease are risk factors for kidney cancer.09/28/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 28, 2018 Category: Urology & Nephrology Source Type: news

Renal Cell Carcinoma Center of Excellence
We invite you to become a member of PracticeUpdate and the Renal Cell Carcinoma Center of Excellence, an expert-curated resource that ’s dedicated to practicing physicians. The Renal Cell Carcinoma Center of Excellence provides physicians with the most up to date information on patient care.09/27/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 27, 2018 Category: Urology & Nephrology Source Type: news

New nanotherapy offers hope in treating drug-resistant renal cell carcinoma
A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma.09/26/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 26, 2018 Category: Urology & Nephrology Source Type: news

Obesity could overtake smoking as biggest preventable cause of cancer in women
Being overweight or obese as an adult increases the risk of 13 different types of cancer including breast, bowel and kidney cancer, but only around one in seven people in the UK are aware of the link.09/24/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 24, 2018 Category: Urology & Nephrology Source Type: news

New nanotherapy offers hope in treating drug-resistant renal cell carcinoma
(Wayne State University - Office of the Vice President for Research) A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 21, 2018 Category: International Medicine & Public Health Source Type: news

Susan describes her cancer diagnosis at age 25
Susan from Alberta, Canada, was diagnosed with stage 1 kidney cancer at age 25. After receiving a radical right nephrectomy, she has remained cancer-free for 12 years. Below, Susan shares her best advice for those going through a similar situation: 1.) Ask questions and record everything so you can remember what the doctor says. It will also serve as a journal for you down the road. 2.) Be kind to yourself. There will be bad days, hard days, but there will be many good days as well so enjoy those when they come. 3.) Let your close loved ones know when you are having a bad day, don ’t keep your feelings to yourself...
Source: Kidney Cancer Association - September 20, 2018 Category: Urology & Nephrology Source Type: news

NLR Predicts Survival After Cytoreductive Nephrectomy+Thrombectomy
Preoperative neutrophil-lymphocyte ratio (NLR) may predict survival following cytoreductive nephrectomy plus thrombectomy for renal cell carcinoma (RCC), a new study suggest.09/19/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 19, 2018 Category: Urology & Nephrology Source Type: news

Kidney Cancer: Risk Factors and Prevention
This article discusses the risk factors that can cause kidney cancer and what people can do to lower their chances of developing the condition.09/19/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 19, 2018 Category: Urology & Nephrology Source Type: news

Combinations Poised to Carry Clinical Benefit in RCC
In this Q&A article, Bradley McGregor, M.D., explains how combination therapy will have a global impact on patients.09/18/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 18, 2018 Category: Urology & Nephrology Source Type: news

10 Healthy Reasons to Eat a Banana Every Day
Researchers found that people who ate lots of fruits and vegetables - more than 75 servings per month, or roughly three servings total per day - had the lowest risk of developing renal cell carcinoma. When researchers looked at fruit specifically, bananas seemed to be the most beneficial due to their high concentration of antioxidants.09/18/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 18, 2018 Category: Urology & Nephrology Source Type: news

Pfizer, Merck immunotherapy combo delays kidney cancer progression
Bavencio, which was developed together with Pfizer, was found to delay the progression of kidney cancer when used with Pfizer ’s Inlyta (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - September 11, 2018 Category: Pharmaceuticals Source Type: news

For new cancer treatments, less is more
People with advanced kidney cancer can skip surgery to have their kidneys removed and instead go right to drug treatment, a recent study showed.09/11/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 11, 2018 Category: Urology & Nephrology Source Type: news

Dawnia survives kidney cancer after receiving a nephrectomy on her right kidney
Five years ago, Dawnia, who lives in Texas, was diagnosed with stage II kidney cancer at age 50. During a routine visit at her gynecologist ’s office, the nurse practitioner was alarmed when she learned that Dawnia’s mother was recently diagnosed with kidney cancer. The nurse urged her to get an ultrasound which showed a 9×9 tumor. Dawnia credits her nurse practitioner’s suggestion of getting an ultrasound with saving her life. S he has remained cancer-free following her nephrectomy. No chemotherapy or radiation was required. Dawnia had chest x-rays and abdominal CT scans every three to six months f...
Source: Kidney Cancer Association - September 11, 2018 Category: Urology & Nephrology Source Type: news

Merck KGaA, Pfizer's immuno-drug shown to alleviate kidney cancer
Merck KGaA said that its immunotherapy Bavencio, jointly developed with Pfizer, delayed the progression of kidney cancer when used in combination with Pfizer's Inlyta drug in a late-stage study. (Source: Reuters: Health)
Source: Reuters: Health - September 11, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

A healthy, organic diet lowers your risk of cancer by a whopping 65%
According to a recent study by the University of Florida, a healthy organic diet that is rich in fruits, vegetables and dairy can help lower your cancer risk by 65 percent. The study also states that avoiding tobacco can help lower your risk of developing kidney cancer.09/10/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - September 10, 2018 Category: Urology & Nephrology Source Type: news

' Jury Still Out' on Adjuvant Therapy in Kidney Cancer'Jury Still Out' on Adjuvant Therapy in Kidney Cancer
Although sunitinib improves disease-free survival in high-risk resected renal cancer and adverse events are manageable, many patients discontinue therapy, and its role is a matter of debate, say experts.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 6, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Watching kidney cancer metabolism
(Source: ScienceNOW)
Source: ScienceNOW - September 6, 2018 Category: Science Authors: Yang, M. Tags: twil Source Type: news

Simple CT Scan Eliminates Need for Surgery in Kidney Cancer Simple CT Scan Eliminates Need for Surgery in Kidney Cancer
A simple CT scan measurement discriminates between a benign form of kidney cancer and a more lethal subtype with high degree of accuracy, allowing surgery to be avoided.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - September 5, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news

A Genetic Cause for Kidney Cancer
UNC scientists have discovered some really interesting information about how RCCC develops, providing new pathways for targeted therapies. Targeted therapies are those that work by zeroing in on a specific pathway in the cancer ’s development. In this case, Qing Zhang, PhD, and his team of fellow scientists saw that in 90% of RCCC, an important tumor suppressor gene called VHL was either missing or malfunctioning. When this happens, a protein called ZHX2 accumulates in high quantities in the renal cells. The VHL gene l oss is responsible in not only in the origination of the tumor(s), but also plays a key role in the...
Source: Kidney Cancer Association - September 4, 2018 Category: Urology & Nephrology Source Type: news

Blood Biomarker May Help Identify Those at Increased Risk for RCC
Concentrations of KIM-1 in the blood may predict for renal cell carcinoma up to 5 years prior to diagnosis. (Source: CancerNetwork)
Source: CancerNetwork - August 30, 2018 Category: Cancer & Oncology Authors: Leah Lawrence Source Type: news

Imaging for Screening and Surveillance of Patients with Hereditary Forms of Renal Cell Carcinoma
According to the University of Texas, 5-8% of RCC cases are hereditary.08/29/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 29, 2018 Category: Urology & Nephrology Source Type: news

New test uncovers metabolic vulnerabilities in kidney cancer
(UT Southwestern Medical Center) A team of investigators used intraoperative infusions of labeled glucose in patients about to have surgery to remove the kidney cancer to assess how the tumors use glucose. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 29, 2018 Category: International Medicine & Public Health Source Type: news

Immunotherapy: What Makes this Cancer Treatment So Promising?
Immunotherapy to treat cancer has been around for a while, but new research is making headway in directions that are both exciting and are giving hope to patients fighting cancer. In this video, Dr Shubham Pant, an oncologist in Houston Texas, demystifies immunotherapy.08/28/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 28, 2018 Category: Urology & Nephrology Source Type: news

Young Investigator Award winner Dr. Liam Macleod discusses his research on regionalization
Since 2006, the Kidney Cancer Association has supported an annual Young Investigator Award (YIA) through the Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO). The YIA supported by Kidney Cancer Association provides funding to promising doctors to pursue careers in kidney cancer research. This year, the Kidney Cancer Association supported two awards – a YIA and an ASCO Annual Meeting Merit Award – through the Conquer Cancer Foundation. The 2018 Conquer Cancer Foundation of ASCO/Kidney Cancer Association YIA recipient, Liam C. Macleod, M.D., M.P.H., is currently completing his s eco...
Source: Kidney Cancer Association - August 28, 2018 Category: Urology & Nephrology Source Type: news

UNDER THE MICROSCOPE:  Nicholas Owen, 71, answers our health quiz 
The award-winning journalist was diagnosed with kidney cancer in 2002, suffered DVT and had his appendix removed ten years ago. But he still thinks occasional wine and regular sex are important... (Source: the Mail online | Health)
Source: the Mail online | Health - August 27, 2018 Category: Consumer Health News Source Type: news

My patients are dying. But it ’s their right to keep going.
Isaac Chan, a medical oncology fellow at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, discusses a patient's right to refuse palliative care.08/27/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 27, 2018 Category: Urology & Nephrology Source Type: news

Kuzel Discusses Treatment Options for Metastatic RCC Based on Risk Stratification
Dr. Kuzel discusses treatment options for metastatic RCC based on risk stratification. In the article, Dr. Kuzel talks about two different case scenarios.08/27/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 27, 2018 Category: Urology & Nephrology Source Type: news

"Kidney Cancer" Journal Release New Issue
The newest issue of the journal, “Kidney Cancer” just came out! The issue includes two review articles on the topics of diagnostic imaging and adjuvant therapy, a commentary about partial nephrectomy and five research articles, plus a new Clinical Trials Corner.08/24/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 24, 2018 Category: Urology & Nephrology Source Type: news

Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma
Although a subset of clear cell renal cell carcinoma (ccRCC) patients respond to immune checkpoint blockade (ICB), predictors of response remain uncertain.08/24/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 24, 2018 Category: Urology & Nephrology Source Type: news

Selecting Patients With Renal Cell Carcinoma for Adjuvant Sunitinib Therapy
Daniel J. George, MD, professor of medicine and surgery at Duke Cancer Institute, discusses his rationale for choosing patients with renal cell carcinoma (RCC) that should receive adjuvant sunitinib (Sutent) therapy.08/23/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 23, 2018 Category: Urology & Nephrology Source Type: news

African Americans Urged To Consider Clinical Trials
An initiative launched today encourages newly-diagnosed African American cancer patients in Maryland to consider clinical trials as the first-line option, not the last resort. The ads are intended to reward those progressive physicians who are actively supporting their patients ’ access to the most advanced options for improved care, including clinical trials for prostate, bladder and kidney cancer.08/23/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 23, 2018 Category: Urology & Nephrology Source Type: news

Diabetes Can Develop in Cancer Patients Treated With Checkpoint Inhibitors
Cancer treatment has been transformed by the use of monoclonal antibodies (mAbs) that block immune inhibitory ligands CTLA-4 and PD-1, known as immune checkpoint inhibitors (CPIs). With these options for treatment of cancers that are resistant to conventional cancer therapies, the life expectancy of patients with melanoma, lung cancer, renal cell carcinoma, and other cancers, has shown significant improvement. However, according to the journal Diabetes, some patients experience adverse effects. One percent of patients treated with anti –PD-1 or –PD-L1 CPIs develop diabetes.08/22/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 22, 2018 Category: Urology & Nephrology Source Type: news

Case Studies: Treatment of Refractory Metastatic Renal Cell Carcinoma
Thomas Hutson, DO, PharmD, reviews the case of a 70-year old woman who presents with symptomatic, metastatic clear cell renal cell carcinoma.08/21/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 21, 2018 Category: Urology & Nephrology Source Type: news