Associations of retinal microvascular caliber with large arterial function and structure: A population ‐based study of 11‐12 year‐olds and mid‐life adults
ConclusionsNarrower retinal arterioles and wider venules are associated with large arterial function as early as mid ‐childhood. Associations strengthen by mid‐life and also extend to arterial structure, although effect sizes remain small. (Source: Microcirculation)
Source: Microcirculation - June 2, 2020 Category: Research Authors: Mengjiao Liu,
Kate Lycett,
Tien Yin Wong,
Anneke Grobler,
Markus Juonala,
Mingguang He,
Terry Dwyer,
David Burgner,
Melissa Wake Tags: ORIGINAL RESEARCH Source Type: research
Issue Information
Microcirculation, Volume 27, Issue 4, May 2020. (Source: Microcirculation)
Source: Microcirculation - May 24, 2020 Category: Research Tags: ISSUE INFORMATION Source Type: research
BCR ‐ABL Tyrosine Kinase Inhibitors Promote Pathological Changes in Dilator Phenotype in the Human Microvasculature
ConclusionIncubating human arterioles with imatinib or nilotinib switches the mediator of FMD from vasoprotective nitric oxide to pro ‐inflammatory H2O2. (Source: Microcirculation)
Source: Microcirculation - May 11, 2020 Category: Research Authors: Matthew J. Durand,
Shelby N. Hader,
Alexa Derayunan,
Natalya Zinkevich,
Jennifer J. McIntosh,
Andreas M. Beyer Tags: ORIGINAL RESEARCH Source Type: research
Adenosine Kinase Inhibition Enhances Microvascular Dilator Function and Improves Left Ventricle Diastolic Dysfunction
ConclusionsOur results indicate that ADK inhibition selectively enhances microvascular vasodilator function, whereby it improves LV perfusion and LV contractile function under metabolic and hemodynamic stress. (Source: Microcirculation)
Source: Microcirculation - April 29, 2020 Category: Research Authors: Alec Davila,
Yanna Tian,
Istvan Czikora,
Amanda Weissman,
Nicholas Weinand,
Guangkuo Dong,
Jiean Xu,
Jie Li,
Huabo Su,
Gaston Kapuku,
Yuqing Huo,
Zsolt Bagi Tags: ORIGINAL RESEARCH Source Type: research
Non ‐invasive measurement of retinal permeability in a diabetic rat model
ConclusionsThis novel imaging methodology in combination with mathematical quantification allows retinal permeability to be non ‐invasively and accurately measured at multiple time points in the same animal. In addition, this technique is a non‐toxic, rapid, sensitive and cost‐effective alternative to the Evans blue assay. (Source: Microcirculation)
Source: Microcirculation - April 29, 2020 Category: Research Authors: Claire L Allen,
Naseeb K Malhi,
Jaqueline D Whatmore,
David O Bates,
Kenton P Arkill Tags: ORIGINAL RESEARCH Source Type: research
The impact of maternal asthma during pregnancy on offspring retinal microvascular structure and its relationship to placental growth factor production in utero
This study explored whether maternal asthma in pregnancy is associated with the development of offspring microvascular structure and if it was related to biomarkers of angiogenesisin utero. Children aged 4 to 6 years, born to either asthmatic mothers (n=38) or healthy controls (n=25) had their retinal microvascular structure examined. Maternal plasma placental growth factor (PlGF) concentrations at 18 and 36 weeks gestation were measured. There was a significant global difference in all retinal microvascular measures between children of asthmatic mothers relative to controls and increased retinal venular tortuosity in chil...
Source: Microcirculation - April 23, 2020 Category: Research Authors: Ailee R. Jones,
Christine Tuckwell,
Ian M.R. Wright,
Janna L. Morrison,
Yogavijayan Kandasamy,
Melanie R. Wittwer,
Margaret A. Arstall,
Michael J Stark,
Michael Davies,
Cameron Hurst,
Satomi Okano,
Vicki L. Clifton Tags: ORIGINAL RESEARCH Source Type: research
Individual cell motion in healthy human skin microvasculature by reflectance confocal video microscopy
ConclusionsThe proposed method and reported values in healthy skin provide new insights into intact human skin microcirculation. (Source: Microcirculation)
Source: Microcirculation - April 16, 2020 Category: Research Authors: Inga Saknite,
Zijun Zhao,
J. Randall Patrinely,
Michael Byrne,
Madan Jagasia,
Eric R. Tkaczyk Tags: ORIGINAL RESEARCH Source Type: research
Cover Image
Cover Caption: The cover image is based on the Original Article In vivo imaging of hemodynamic redistribution and arteriogenesis across microvascular network by Song Hu et al.,https://doi.org/10.1111/micc.12598. (Source: Microcirculation)
Source: Microcirculation - April 13, 2020 Category: Research Authors: Naidi Sun,
Bo Ning,
Anthony C. Bruce,
Rui Cao,
Scott A. Seaman,
Tianxiong Wang,
Regina Fritsche ‐Danielson,
Leif G. Carlsson,
Shayn M. Peirce,
Song Hu Tags: COVER IMAGE Source Type: research
Issue Information
Microcirculation, Volume 27, Issue 3, April 2020. (Source: Microcirculation)
Source: Microcirculation - April 13, 2020 Category: Research Tags: ISSUE INFORMATION Source Type: research
Sigma ‐1 Receptor Activation‐Induced Glycolytic ATP Production and Endothelial Barrier Enhancement
ConclusionActivation of σ1 enhances endothelial barrier function and modulates the ratio of glycolytic versus mitochondrial ATP production. These novel findings suggest that endothelial σ1 may prove beneficial as a novel therapeutic target for reducing microvascular hyperpermeability and counteracting mitochondrial dysfu nction. (Source: Microcirculation)
Source: Microcirculation - April 11, 2020 Category: Research Authors: Zeinab Y. Motawe,
Forouzandeh Farsaei,
Salma S. Abdelmaboud,
Javier Cuevas,
Jerome W. Breslin Tags: ORIGINAL RESEARCH Source Type: research
Issue Information
Microcirculation, Volume 27, Issue 2, February 2020. (Source: Microcirculation)
Source: Microcirculation - March 21, 2020 Category: Research Tags: ISSUE INFORMATION Source Type: research
The British Microcirculation Society
Microcirculation, Volume 27, Issue 2, February 2020. (Source: Microcirculation)
Source: Microcirculation - March 21, 2020 Category: Research Tags: ABSTRACTS Source Type: research
Cover Image
Cover Caption: The cover image is based on the Original Article Lymphatic ‐to‐Blood Vessel Transition in Adult Microvascular Networks: A Discovery Made Possible by a Top‐Down Approach to Biomimetic Model Development by Walter Murfee et al.,https://doi.org/10.1111/micc.12595. (Source: Microcirculation)
Source: Microcirculation - March 21, 2020 Category: Research Authors: Mohammad S. Azimi,
Jessica M. Motherwell,
Nicholas A. Hodges,
Garret R. Rittenhouse,
Dima Majbour,
Stacey L. Porvasnik,
Christine E. Schmidt,
Walter L. Murfee Tags: COVER IMAGE Source Type: research
The influence of hyperglycemia on neutrophil extracellular trap formation and endothelial glycocalyx damage in a mouse model of type 2 diabetes
ConclusionNeutrophil activation and cell death induce endothelial glycocalyx damage, and NETs formation also participates in the mechanisms of vascular injury in type 2 diabetes. (Source: Microcirculation)
Source: Microcirculation - March 21, 2020 Category: Research Authors: Tatsuhiko Hirota,
Jerrold H. Levy,
Toshiaki Iba Tags: ORIGINAL RESEARCH Source Type: research
Sublingual microcirculation in prehospital critical care medicine: A proof ‐of‐concept study
ConclusionThe prehospital sublingual measurement is safe and valid. Despite normal macrocirculation, microcirculation was impaired and correlated with National Advisory Committee on Aeronautics. (Source: Microcirculation)
Source: Microcirculation - March 21, 2020 Category: Research Authors: Raphael Romano Bruno,
Markus Reed,
Nana ‐Yaw Bimpong‐Buta,
Johanna M. Muessig,
Maryna Masyuk,
Stephan Binneboessel,
Marcus Franz,
Malte Kelm,
Christian Jung Tags: ORIGINAL ARTICLE Source Type: research
