Three ‐dimensional spatial quantitative analysis of cardiac lymphatics in the mouse heart
ConclusionsThis workflow and study enabled multi-scale analysis of pathological changes in cardiac LyVs of young adult mice, inviting ideas for research on LyVs in cardiac disease. (Source: Microcirculation)
Source: Microcirculation - August 22, 2023 Category: Research Authors: Evan H. Phillips,
Vytautas P. Bindokas,
Dahee Jung,
Jay Teamer,
Jan K. Kitajewski,
R. John Solaro,
Beata M. Wolska,
Steve Seung ‐Young Lee Tags: ORIGINAL ARTICLE Source Type: research
Cover Image
The cover image is based on the Original ArticleVariations in mechanical stiffness alter microvascular sprouting and stability in a PEG hydrogel model of idiopathic pulmonary fibrosis by Julie Leonard-Dukeet al.,https://doi.org/10.1111/micc.12817. (Source: Microcirculation)
Source: Microcirculation - August 10, 2023 Category: Research Authors: Julie Leonard ‐Duke,
Anthony C. Bruce,
Shayn M. Peirce,
Lakeshia J. Taite Tags: COVER IMAGE Source Type: research
Corrigendum
(Source: Microcirculation)
Source: Microcirculation - August 10, 2023 Category: Research Tags: CORRIGENDUM Source Type: research
Issue Information
(Source: Microcirculation)
Source: Microcirculation - August 10, 2023 Category: Research Tags: ISSUE INFORMATION Source Type: research
Beneficial effects of empagliflozin and liraglutide on the cerebral microcirculation of diabetic rats
ConclusionThese findings suggest that chronic treatment with SGLT2 inhibitors and GLP-1 receptor agonists may serve as potential therapeutic approaches to prevent microvascular complications associated with diabetes. (Source: Microcirculation)
Source: Microcirculation - August 8, 2023 Category: Research Authors: Joana Costa d'Avila,
Aluana Santana Carlos,
Raimundo Lima Vieira,
Carla Vergueiro,
Aline Teixeira Lima,
Isaias dos Santos Silva,
Vivian Carvalho Figueiredo,
Paulo Henrique Petrone Chateaubriand,
Adalgiza Mafra Moreno,
Hugo Caire Castro Faria N Tags: ORIGINAL ARTICLE Source Type: research
Removal of the endothelial surface layer via hyaluronidase does not modulate monocyte and neutrophil interactions with the glomerular endothelium
ConclusionsThese observations indicate that, despite evidence that the ESL has the capacity to inhibit leukocyte-endothelial cell interactions while also containing adhesive ligands for immune cells, neither of these functions modulate trafficking of monocytes and neutrophils in steady-state or acutely-inflamed glomeruli. (Source: Microcirculation)
Source: Microcirculation - July 27, 2023 Category: Research Authors: ZheHao Tan,
Pam Hall,
Adam Costin,
Simon A. Crawford,
Georg Ramm,
Connie H. Y. Wong,
A. Richard Kitching,
Michael J. Hickey Tags: ORIGINAL ARTICLE Source Type: research
Microvascular dysfunction in patients with heart failure with preserved ejection fraction: A meta ‐analysis
ConclusionsThis meta-analysis revealed that approximately 50% of patients diagnosed with HFpEF exhibited MVD. Moreover, the presence of MVD demonstrated significant prognostic implications in multiple studies conducted on patients with HFpEF. These findings strongly suggest that MVD plays a crucial role in the underlying pathophysiology of patients with HFpEF. (Source: Microcirculation)
Source: Microcirculation - July 26, 2023 Category: Research Authors: Mai Azuma,
Shingo Kato,
Kazuki Fukui,
Nobuyuki Horita,
Daisuke Utsunomiya Tags: ORIGINAL ARTICLE Source Type: research
Extended ‐volume image‐derived models of coronary microcirculation
ConclusionThe tools and techniques from this study will serve other investigations into the microcirculation, and the wealth of data from this study will enable the analysis of biophysical mechanisms using computer models. (Source: Microcirculation)
Source: Microcirculation - July 2, 2023 Category: Research Authors: Vibujithan Vigneshwaran,
Christine Lauren Sy,
Bruce H. Smaill,
Gregory B. Sands,
Nicolas P. Smith Tags: ORIGINAL ARTICLE Source Type: research
The sublingual microcirculation and frailty index in chronic kidney disease patients
ConclusionsThere is a relationship between the frailty index and microcirculatory health in those attending a kidney transplant assessment clinic, that is not confounded by age. These findings suggest that the impaired microcirculation may be an underlying cause of frailty. (Source: Microcirculation)
Source: Microcirculation - June 8, 2023 Category: Research Authors: Ryan A. P. Homes,
Fiona Giddens,
Ross S. Francis,
Ruth E. Hubbard,
Emily H. Gordon,
Mark J. Midwinter Tags: ORIGINAL ARTICLE Source Type: research
Variations in mechanical stiffness alter microvascular sprouting and stability in a PEG hydrogel model of idiopathic pulmonary fibrosis
ConclusionsWe have developed a novel, tunable hydrogel assay for the creation of lung explant vessel organoids which can be modulated to study the impact of specific environmental cues on vessel formation and maturation. (Source: Microcirculation)
Source: Microcirculation - May 30, 2023 Category: Research Authors: Julie Leonard ‐Duke,
Anthony C. Bruce,
Shayn M. Peirce,
Lakeshia J. Taite Tags: ORIGINAL ARTICLE Source Type: research
Circadian and sex differences in post ‐ischemic vasodilation and reactive hyperemia in young individuals and elderly with and without type 2 diabetes
ConclusionsForearm vasodilation following reperfusion is attenuated in the morning in the elderly, impairing BF towards an ischemic area. Diabetes does not affect the circadian regulation of VC and BF, but that of MAP. There are sex differences in VC and BF at baseline and after circulatory reperfusion at a young age, being greater in men, which disappear with aging without being affected by diabetes. (Source: Microcirculation)
Source: Microcirculation - May 29, 2023 Category: Research Authors: Alessandro Gentilin,
Paolo Moghetti,
Antonio Cevese,
Anna Vittoria Mattioli,
Federico Schena,
Cantor Tarperi Tags: ORIGINAL ARTICLE Source Type: research
5 ‐HT7 receptors mediate dilation of rat cremaster muscle arterioles in vivo
Conclusions5-HT7 receptors mediate dilation of small arterioles in skeletal muscle and likely contribute to 5-HT-induced hypotension, in vivo. (Source: Microcirculation)
Source: Microcirculation - May 20, 2023 Category: Research Authors: William F. Jackson,
Armond Daci,
Janice M. Thompson,
Gregory D. Fink,
Stephanie W. Watts Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Microcirculation)
Source: Microcirculation - May 10, 2023 Category: Research Tags: ISSUE INFORMATION Source Type: research
Impaired peripheral microvascular reactivity in patients with nonobstructive coronary artery disease
ConclusionAngina patients with NOCAD have microvascular dysfunction as demonstrated by reduced magnitude of reperfusion with an ischemic stimulus. NOCAD patients without coronary obstruction also displayed a slower response to reperfusion. (Source: Microcirculation)
Source: Microcirculation - April 21, 2023 Category: Research Authors: Zulkefli Sanip,
Nurnajwa Pahimi,
Nur Adilah Bokti,
Zurkurnai Yusof,
Mohd Sapawi Mohamed,
W. Yus Haniff W. Isa,
Aida Hanum Rasool Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Microcirculation)
Source: Microcirculation - April 20, 2023 Category: Research Tags: ISSUE INFORMATION Source Type: research
