Issue Information ‐Calendar of Events
Microcirculation, Volume 27, Issue 8, November 2020. (Source: Microcirculation)
Source: Microcirculation - November 20, 2020 Category: Research Tags: ISSUE INFORMATION ‐Calendar of Events Source Type: research

Issue Information
Microcirculation, Volume 27, Issue 8, November 2020. (Source: Microcirculation)
Source: Microcirculation - November 20, 2020 Category: Research Tags: ISSUE INFORMATION Source Type: research

Withdrawn: Long noncoding RNA XIST participates hypoxia ‐induced angiogenesis in human brain microvascular endothelial cells through regulating miR 485/SOX7 axis
Withdrawal: Hu C, Bai X, Liu C, Hu Z. Long noncoding RNA XIST participates hypoxia ‐induced angiogenesis in human brain microvascular endothelial cells through regulating miR‐485/SOX7 axis. Microcirculation. 2019 (https://doi.org/10.1111/micc.12601)The above article, published online on 29 November 2019 in Wiley Online Library (wileyonlinelibrary.com), has been withdrawn at the request of the authors. The withdrawal has been agreed by the journal Editor in Chief Donald Welsh, and by John Wiley& Sons Ltd. due to major overlap with a previously published article from the same group of authors. (Source: Microcirculation)
Source: Microcirculation - November 20, 2020 Category: Research Tags: WITHDRAWAL Source Type: research

A Clinical Perspective on Adipose ‐Derived Cell Therapy for Enhancing Microvascular Health and Function: Implications and Applications for Reconstructive Surgery
The objective of this article is to share the clinical perspectives of reconstructive plastic surgeons regarding the use of ADC based therapies to help with flap‐tissue integration, revascularization and wound healing. Specifically, the focus will be on considering the potenti al for ADC as therapeutic agents and how their clinical application motivates basic science opportunities. (Source: Microcirculation)
Source: Microcirculation - November 11, 2020 Category: Research Authors: V. Morgan Jones, Ariana D. Suarez ‐Martinez, Nicholas A. Hodges, Walter L. Murfee, Ramon Llull, Adam J. Katz Tags: INVITED REVIEW Source Type: research

The Cerebral Microvasculature: Basic and Clinical Perspectives on Stroke and Glioma
AbstractMicrovascular networks are vital components of the cardiovascular system, performing many key roles in maintaining the health and homeostasis of the tissues and organs in which they develop. As discussed in this review, the molecular and cellular components within the microcirculation orchestrate critical processes to establish functional capillary beds, including organization of endothelial cell (EC) polarity, guiding investment of vascular pericytes (PCs), and building the specialized extracellular matrix (ECM) that comprises the vascular basement membrane (vBM). Herein, we further discuss the unique features of ...
Source: Microcirculation - November 10, 2020 Category: Research Authors: Maruf M. Hoque, Hanaa Abdelazim, Clifton Jenkins ‐Houk, Dawn Wright, Biraj M. Patel, John C. Chappell Tags: INVITED REVIEW Source Type: research

The effect of blood transfusion on sublingual microcirculation in critically ill patients: A scoping review
ConclusionsThis scoping review has catalogued evidence that RBC transfusion differently improves sublingual microcirculation in different populations. The existing evidence is not sufficient to conclude the effects of the leukoreduction and storage time of RBCs. (Source: Microcirculation)
Source: Microcirculation - November 9, 2020 Category: Research Authors: Wanglin Liu, Huaiwu He, Can Ince, Yun Long Tags: Original Article Source Type: research

Effects of exenatide on microvascular reactivity in patients with type 2 diabetes and coronary artery disease, a randomized controlled study
ConclusionsThree months daily treatment with the GLP ‐1RA exenatide in T2DM patients with CAD showed no significant effects on skin microvascular function or blood glucose control, while this study confirms a reduction in body weight and blood pressure by exenatide, as compared to conventional antidiabetic drug treatment. (Source: Microcirculation)
Source: Microcirculation - November 5, 2020 Category: Research Authors: Nikolaos Östlund Papadogeorgos, Jeanette Kuhl, Angela Shore, Thomas Kahan, Gun Jörneskog, Majid Kalani Tags: ORIGINAL ARTICLE Source Type: research

Mild obesity does not affect the forearm muscle microvascular responses to hyperglycemia
ConclusionEven though obese individuals showed impaired postprandial brachial artery function, the current findings suggest that mild obesity does not affect the forearm skeletal muscle responses to glucose ingestion. (Source: Microcirculation)
Source: Microcirculation - November 4, 2020 Category: Research Authors: Rog ério Nogueira Soares, Raylene A. Reimer, Patricia K. Doyle‐Baker, Juan M. Murias Tags: ORIGINAL ARTICLE Source Type: research

Effect of cytosol viscosity on the flow behavior of red blood cell suspensions in microvessels
ConclusionsThe weak effect on the flow resistance and RBC ‐FL explains why RBCs can contain a high concentration of hemoglobin for efficient oxygen delivery, without a pronounced increase in the flow resistance. Furthermore, our results suggest that significant alterations in microvascular flow in various pathologies are likely not due to mere changes in cytosolic viscosity. (Source: Microcirculation)
Source: Microcirculation - November 1, 2020 Category: Research Authors: Wei Chien, Gerhard Gompper, Dmitry A. Fedosov Tags: ORIGINAL ARTICLE Source Type: research

Cover Image
The cover image is based on the Original ArticleThe need to freeze ‐ dehydration during specimen preparation for electron microscopy collapses the endothelial glycocalyx regardless of fixation method by Casper Hempel et al.,https://doi.org/10.1111/micc.12643. (Source: Microcirculation)
Source: Microcirculation - October 30, 2020 Category: Research Authors: Casper Hempel, Sergey Kapishnikov, Ana Joaquina Perez ‐Berna, Stephan Werner, Peter Guttmann, Eva Pereiro, Klaus Qvortrup, Thomas Lars Andresen Tags: COVER IMAGE Source Type: research

Issue Information
Microcirculation, Volume 27, Issue 7, October 2020. (Source: Microcirculation)
Source: Microcirculation - October 30, 2020 Category: Research Tags: ISSUE INFORMATION Source Type: research

Microvascular dysfunction and kidney disease: Challenges and opportunities?
The objective of this rev iew is to highlight the role of renal microvasculature in kidney disease. The overview will outline the impetus to study renal microvasculature, the bidirectional relationship between kidney disease and microvascular dysfunction, the key pathways driving microvascular diseases such as vasoreactivity , the cell dynamics coordinating fibrosis, and vessel rarefaction. Finally, we will also briefly highlight new therapies targeting the renal microvasculature to improve renal function. (Source: Microcirculation)
Source: Microcirculation - October 28, 2020 Category: Research Authors: Suraj Krishnan, Ariana D. Suarez ‐Martinez, Pooneh Bagher, Anjelica Gonzalez, Ruisheng Liu, Walter L. Murfee, Rajesh Mohandas Tags: ORIGINAL ARTICLE Source Type: research

The Effect of Blood Transfusion on Sublingual Microcirculation in Critically Ill Patients: A Scoping Review
ConclusionsThis scoping review has catalogued evidence that RBC transfusion differently improves sublingual microcirculation in different populations. The existing evidence is not sufficient to conclude the effects of the leukoreduction and storage time of RBCs. (Source: Microcirculation)
Source: Microcirculation - October 22, 2020 Category: Research Authors: Wanglin Liu, Huaiwu He, Can Ince, Yun Long Tags: ORIGINAL ARTICLE Source Type: research

The presence of diabetes mellitus further impairs structural and functional capillary density in patients with chronic kidney disease.
ConclusionsCapillary density during postocclusive hyperemia and after venous congestion is lower in diabetic compared to non ‐diabetic CKD patients, a finding indicative that diabetes is an additional factor contributing to microcirculatory structural and functional impairment in CKD. These differences are more prominent in CKD stage 3b. (Source: Microcirculation)
Source: Microcirculation - October 16, 2020 Category: Research Authors: Maria Schoina, Charalampos Loutradis, Marieta Theodorakopoulou, Theodoros Dimitroulas, Eva Triantafillidou, Michael Doumas, Asterios Karagiannis, Alexandros Garyfallos, Aikaterini Papagianni, Pantelis Sarafidis Tags: ORIGINAL RESEARCH Source Type: research

Systemic microvascular endothelial dysfunction is associated with left ventricular ejection fraction reduction in chronic Chagas ’ disease patients.
ConclusionsWe have shown for the first time that the reduction of MR is associated with a decrease of LVEF in a cohort of chronic CD patients. The results were not affected by comorbidities, such as hypertension or diabetes. The evaluation of systemic endothelial function may be useful to tailor therapeutic and preventive approaches, targeted at systolic left ventricular failure associated with chronic CD cardiomyopathy. (Source: Microcirculation)
Source: Microcirculation - October 16, 2020 Category: Research Authors: Daniel Arthur Barata Kasal, Ademar Britto, Val éria Verri, Andrea De Lorenzo, Eduardo Tibiriçá Tags: ORIGINAL RESEARCH Source Type: research