Microvascular dysfunction and kidney disease: Challenges and opportunities?

The objective of this rev iew is to highlight the role of renal microvasculature in kidney disease. The overview will outline the impetus to study renal microvasculature, the bidirectional relationship between kidney disease and microvascular dysfunction, the key pathways driving microvascular diseases such as vasoreactivity , the cell dynamics coordinating fibrosis, and vessel rarefaction. Finally, we will also briefly highlight new therapies targeting the renal microvasculature to improve renal function.

Source: Microcirculation - October 28, 2020 Category: Research Authors: Suraj Krishnan, Ariana D. Suarez ‐Martinez, Pooneh Bagher, Anjelica Gonzalez, Ruisheng Liu, Walter L. Murfee, Rajesh Mohandas Tags: ORIGINAL ARTICLE Source Type: research