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Hyperoxia does not affect oxygen delivery in healthy volunteers while causing a decrease in sublingual perfusion
Abstract ObjectiveTo determine the human dose‐response relationship between a stepwise increase in arterial oxygen tension and its associated changes in oxygen delivery and sublingual microcirculatory perfusion MethodsFifteen healthy volunteers breathed increasing oxygen fractions for 10 minutes to reach arterial oxygen tensions of baseline (breathing air), 20 kPa, 40 kPa, 60 kPa and max kPa (breathing oxygen). Systemic hemodynamics were measured continuously by the volume‐clamp method. At the end of each period, the sublingual microcirculation was assessed by Sidestream Darkfield Imaging ResultsSystemic oxygen deliver...
Source: Microcirculation - December 6, 2017 Category: Research Authors: B. Smit, Y.M. Smulders, E.C. Eringa, H.P.M.M. Gelissen, A.R.J. Girbes, H.J.S. de Grooth, H.H.M. Schotman, P.G. Scheffer, H.M. Oudemans ‐ van Straaten, A.M.E. Spoelstra ‐ de Man Tags: Original Research Source Type: research

Kv channels and vascular smooth muscle cells proliferation
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 7, 2017 Category: Research Authors: Jos é R. López‐López, Pilar Cidad, M. Teresa Pérez‐García Tags: Invited Reviews Source Type: research

Abstracts from the 42nd Annual Meeting of Japanese Society for Microcirculation March 25th ‐ 26th, 2017 Toyama, Japan
(Source: Microcirculation)
Source: Microcirculation - November 6, 2017 Category: Research Tags: ABSTRACTS Source Type: research

Between ‐day reliability of local thermal hyperemia in the forearm and index finger using single‐point laser Doppler flowmetry
ConclusionsFor all sites, LTH reliability was acceptable for the timing, and for the initial peak and plateau using CVC or %CVC44°C. (Source: Microcirculation)
Source: Microcirculation - November 6, 2017 Category: Research Authors: Gregory W. McGarr, Gary J. Hodges, Stephen S. Cheung Tags: ORIGINAL ARTICLE Source Type: research

Endothelial precursor cells stimulate pericyte ‐like coverage of bone marrow‐derived mesenchymal stem cells through platelet‐derived growth factor‐BB induction, which is enhanced by substance P
ConclusionsBM‐EPCs along with SP promote the pericyte‐like coverage of BM‐MSCs on endothelial tubules possibly through the induction of PDGF‐BB. (Source: Microcirculation)
Source: Microcirculation - November 6, 2017 Category: Research Authors: Mingzi Zhang, Woosung Ahn, Sumin Kim, Hyun Sook Hong, Chengshi Quan, Youngsook Son Tags: ORIGINAL ARTICLE Source Type: research

Dosing of indocyanine green for intraoperative laser fluorescence angiography in kidney transplantation
ConclusionsFluorescence angiography with ICG is an emerging tool for the intraoperative quality control and evaluation of microperfusion in kidney transplantation. A dose of 0.02 mg ICG per kg body weight is recommended to ensure the quantitative assessment with SPY‐Q. (Source: Microcirculation)
Source: Microcirculation - November 6, 2017 Category: Research Authors: Ulrich Rother, Andreas L. H. Gerken, Ioannis Karampinis, Madeline Klumpp, Susanne Regus, Alexander Meyer, Hendrik Apel, Bernhard K. Kr ämer, Karl Hilgers, Werner Lang, Kai Nowak Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: Microcirculation)
Source: Microcirculation - November 6, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research

Regulation of microvascular function by voltage ‐gated potassium channels: new tricks for an “ancient” dog
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Matthew A. Nystoriak, Manuel F. Navedo Tags: Invited Reviews Source Type: research

Perivascular adipose tissue and the dynamic regulation of Kv7 and Kir channels: Implications to resistant hypertension
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Maik Gollasch, Donald G. Welsh, Rudolf Schubert Tags: Invited Reviews Source Type: research

Endovascular Shedding Markers in Patients with Heart Failure with Reduced Ejection Fraction
ConclusionThe glycocalyx shedding marker HA is significantly elevated in a subgroup of HFrEF patients and an independent predictor for worse clinical outcome. Glycocalyx shedding might be an additional factor in the pathophysiology of HF which warrants further investigation.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Petra Nijst, Jirka Cops, Pieter Martens, Quirine Swennen, Matthias Dupont, W.H. Wilson Tang, Wilfried Mullens Tags: Original Article Source Type: research

KV1 channel expression and vasomotor function in human coronary resistance arteries
ConclusionsKV1.5, as a major 4‐AP‐sensitive KV1 channel expressed in coronary VSMCs, mediates cAMP‐mediated dilation in non‐CAD arterioles. The cAMP‐mediated dilation is reduced in CAD coronary arterioles, which is associated with impaired 4‐AP‐sensitive KV channel function.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Yoshinori Nishijima, Ankush Korishettar, Dawid S. Chabowski, Sheng Cao, Xiaodong Zheng, David D. Gutterman, David X. Zhang Tags: Original Research Source Type: research

Treatment strategies in coronary microvascular dysfunction: a systematic review of interventional studies
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Hannah E Suhrs, Marie M Michelsen, Eva Prescott Tags: Reviews Source Type: research

Biophysical properties of microvascular endothelium: Requirements for initiating and conducting electrical signals
ConclusionsHigh Rm makes the endothelium sensitive to electrical stimuli and able to conduct these signals effectively. Whereas the activation of a group of ECs is required to initiate physiologically relevant hyperpolarization, this requirement is increased by myoendothelial coupling and KCa activation along the endothelium inhibits conduction by dissipating electrical signals.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Adam Kapela, Erik J. Behringer, Steven S. Segal, Nikolaos M. Tsoukias Tags: Original Research Source Type: research

Coronary microvascular Kv1 channels as regulatory sensors of intracellular pyridine nucleotide redox potential
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: Marc M. Dwenger, Vahagn Ohanyan, Manuel F. Navedo, Matthew A. Nystoriak Tags: Invited Reviews Source Type: research

Oxygen delivery from the cerebral microvasculature to tissue is governed by a single time constant of approximately 6 seconds
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - November 1, 2017 Category: Research Authors: S J Payne, C Lucas Tags: Original Research Source Type: research

Regulation of voltage ‐gated potassium channels in vascular smooth muscle during hypertension and metabolic disorders
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - October 16, 2017 Category: Research Authors: Madeline Nieves ‐Cintrón, Arsalan U. Syed, Matthew A. Nystoriak, Manuel F. Navedo Tags: Invited Reviews Source Type: research

The British Microcirculation Society
(Source: Microcirculation)
Source: Microcirculation - October 7, 2017 Category: Research Tags: ABSTRACTS Source Type: research

Effects of different ‐intensity laser acupuncture at two adjacent same‐meridian acupoints on nitric oxide and soluble guanylate cyclase releases in human
ConclusionsThis is the first evidence reporting that LA induced significant elevations of NO‐sGC releases over acupoints, and the enhanced signal molecules contribute to local circulation, which improves the beneficial effects of the therapy. (Source: Microcirculation)
Source: Microcirculation - October 7, 2017 Category: Research Authors: Wan ‐Ling Jiang, Hua‐Jiang Wei, Zhou‐Yi Guo, Yi‐Rong Ni, Hong‐Qin Yang, Shu‐Sen Xie Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: Microcirculation)
Source: Microcirculation - October 7, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research

Kv7 potassium channels as signal transduction intermediates in the control of microvascular tone
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - October 4, 2017 Category: Research Authors: Kenneth L. Byron, Lyubov I. Brueggemann Tags: Reviews Source Type: research

Molecular Determinants of Beta ‐adrenergic Signaling to Voltage‐gated K+ Channels in the Cerebral Circulation
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - October 1, 2017 Category: Research Authors: Sung W. Rhee, Nancy J. Rusch Tags: Invited Reviews Source Type: research

Hepatic Transudation Barrier Properties
ConclusionsTaken together, these findings suggest that the hepatic transudation barrier is highly permeable at elevated sinusoidal pressures. These fundamental studies provide a better understanding of the hepatic transudation barrier properties and transudation under conditions that are physiologically and clinically relevant to ascites formation.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - October 1, 2017 Category: Research Authors: R M Dongaonkar, R H Stewart, C M Quick, K L Uray, C S Cox, G A Laine Tags: Original Research Source Type: research

The relationship between forearm skin speed resolved perfusion and oxygen saturation, and finger arterial pulsation amplitudes, as indirect measures of endothelial function
ConclusionWe have demonstrated for the first time, a relationship between forearm skin microcirculatory perfusion and oxygen saturation and finger peripheral arterial tonometry. Both local heating and reactive hyperemia are useful skin provocations. Further studies are needed to understand the precise regulation mechanisms of blood flow and oxygenation during these tests.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - October 1, 2017 Category: Research Authors: Sara Bergstrand, Maria ‐Aurora Morales, Giuseppe Coppini, Marcus Larsson, Tomas Strömberg Tags: Original Research Source Type: research

Increased myoendothelial feedback is associated with increased connexin37 and IK1 channel expression in mesenteric arteries of diet ‐induced hyperhomocysteinemic mice
Abstract ObjectivePreviously, we found that diet‐induced HHcy in mice caused decreased eNOS expression and signaling in mesenteric arteries, but greatly enhanced non‐NOS, non‐prostacyclin‐dependent vasodilation, which involves myoendothelial gap junction (MEJ) communication. To further assess whether HHcy enhances MEJ communication, this study examined endothelium‐dependent attenuation of phenylephrine‐induced vasoconstriction (myoendothelial feedback) and key molecules involved. MethodsMyoendothelial feedback was examined in isolated mouse mesenteric arteries, after 6‐wk diet‐induced HHcy, using pressure m...
Source: Microcirculation - August 31, 2017 Category: Research Authors: Robin C. Looft ‐Wilson, Cara R. Goodell, Christina A. Mutch, Stephanie M. Mutchler, Kayla L. Miller, Monique Guraya Tags: Original Research Source Type: research

Influence of feeding hematocrit and perfusion pressure on hematocrit reduction (F åhræus effect) in an artificial microvascular network
ConclusionsThe magnitude of the network Fåhræus effect in an AMVN is inversely related to feeding hematocrit and perfusion pressure.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 12, 2017 Category: Research Authors: Walter H. Reinhart, Nathaniel Z. Piety, Sergey S. Shevkoplyas Tags: Original Research Source Type: research

Dosing of indocyanine ‐green for intraoperative laser fluorescence angiography in kidney transplantation
ConclusionsFluorescence angiography with ICG is an emerging tool for the intraoperative quality control and evaluation of microperfusion in kidney transplantation. A dose of 0.02 mg ICG per kg body weight is recommended in order to ensure the quantitative assessment with SPY‐Q.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 8, 2017 Category: Research Authors: Ulrich Rother, Andreas L.H. Gerken, Ioannis Karampinis, Madeline Klumpp, Susanne Regus, Alexander Meyer, Hendrik Apel, Bernhard K. Kr ämer, Karl Hilgers, Werner Lang, Kai Nowak Tags: Original Research Source Type: research

Agent ‐based Computational Model of Retinal Angiogenesis Simulates Microvascular Network Morphology as a Function of Pericyte Coverage
ConclusionThis study supports a role for pericytes as a physical buffer to signal propagation during vascular network formation – a barrier that may be important for generating healthy microvascular network patterns.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 8, 2017 Category: Research Authors: Joseph Walpole, Feilim Mac Gabhann, Shayn M Peirce, John C Chappell Tags: Original Research Source Type: research

Short ‐term (48 hours) intravenous serelaxin infusion has no effect on myogenic tone or vascular remodeling in rat mesenteric arteries
Abstract BackgroundShort‐term IV sRLX (recombinant human relaxin‐2) infusion enhances endothelium‐dependent relaxation in mesenteric arteries. This is initially underpinned by increased NO followed by a transition to prostacyclin. The effects of short‐term IV sRLX treatment on pressure‐induced myogenic tone and vascular remodeling in these arteries are unknown. Therefore, we investigated the effects of sRLX infusion on pressure‐induced myogenic tone and passive mechanical wall properties in mesenteric arteries. MethodsMesenteric artery myogenic tone and passive mechanics were examined after 48‐hours and 10‐...
Source: Microcirculation - August 3, 2017 Category: Research Authors: Maria Jelinic, Chen Huei Leo, Sarah A. Marshall, Sevvandi N. Senadheera, Laura J. Parry, Marianne Tare Tags: ORIGINAL ARTICLE Source Type: research

Astrocyte activation and capillary remodeling in modified bilateral common carotid artery occlusion mice
Abstract ObjectiveThe cerebral ischemia leads to brain dysfunction with neuron degeneration and responses from astrocytes and vessels. The aim of this study was to study the changes of astrocyte and microvessel in modified BCCAO mice. MethodsAdult transgenic Tie2‐GFP mice were subjected to modified BCCAO operation and cranial window implantation. CBF and neurological injury were examined after ischemia. Astrocytes and vessels were investigated by two‐photon laser‐scanning microscope and confocal laser‐scanning microscope in vivo. ResultsThe CBF decreased to approximately 40% of the baseline in the ischemic mice (P
Source: Microcirculation - August 3, 2017 Category: Research Authors: Jiangman Song, Di Nan, Qihua He, Lu Yang, Huailian Guo Tags: ORIGINAL ARTICLE Source Type: research

Pericyte modulation by a functional antibody obtained by a novel single ‐cell selection strategy
ConclusionsThe selection method provides an efficient platform for the selection of functional antibodies which target pericytes. We obtain an antibody that interacts with a fibronectin epitope important for pericyte mobility and functionality. Targeting of this epitope in pathologies where pericytes are implicated could potentially be of therapeutic benefit. (Source: Microcirculation)
Source: Microcirculation - August 3, 2017 Category: Research Authors: Jesper Just, Simon Lykkemark, Charlotte H. Nielsen, Ali R. Roshenas, Kim R. Drasbek, Steen V. Petersen, Toke Bek, Peter Kristensen Tags: ORIGINAL ARTICLE Source Type: research

Increased survivability of ischemic skin flap tissue in Flk ‐1+/− mice by Pellino‐1 intervention
ConclusionOur findings reveal that Peli1 is a proangiogenic molecule that acts downstream of VEGF‐Flk‐1 and restores angiogenesis and enhances skin flap survivability. (Source: Microcirculation)
Source: Microcirculation - August 3, 2017 Category: Research Authors: Chandra K. Rednam, Rickesha L. Wilson, Vaithinathan Selvaraju, Muhammad T. Rishi, Mahesh Thirunavukkarasu, Vladimir Coca ‐Soliz, Rajesh Lakshmanan, John A. Palesty, David W. McFadden, Nilanjana Maulik Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: Microcirculation)
Source: Microcirculation - August 3, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research

KV channels and the regulation of vascular smooth muscle tone
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 1, 2017 Category: Research Authors: William F. Jackson Tags: Reviews Source Type: research

Assessment of the test ‐retest reliability of human gingival blood flow measurements by Laser Speckle Contrast Imaging in a healthy cohort
ConclusionsLaser Speckle Contrast Imaging has good short and long‐term reliability regardless of lip retraction or an indirect view. This technique seems to be appropriate for the long‐term clinical follow‐up of gingival microcirculation.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 1, 2017 Category: Research Authors: Eszter Moln ár, Réka Fazekas, Zsolt Lohinai, Zsuzsanna Tóth, János Vág Tags: Original Research Source Type: research

KV channel trafficking and control of vascular tone
This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 1, 2017 Category: Research Authors: Raquibul Hasan, Jonathan H. Jaggar Tags: Invited Reviews Source Type: research

Retinal vessel morphology in rheumatoid arthritis: association with systemic inflammation, subclinical atherosclerosis and cardiovascular risk
We examined retinal microvascular diameters in RA, particularly in regard with systemic inflammation, subclinical atherosclerosis and cardiovascular risk. MethodsRetinal images from RA patients and controls were processed using computerized software, to obtain central retinal arteriolar (CRAE) and venular (CRVE) equivalent and arteriovenous ratio (AVR). Subclinical atherosclerosis was assessed with carotid intima‐media thickness (cIMT), and 10‐year risk of general cardiovascular disease was calculated. ResultsBoth CRAE (78.8±8.9 vs 90.2±9.9 μm, p
Source: Microcirculation - August 1, 2017 Category: Research Authors: Panagiota Anyfanti, Areti Triantafyllou, Eugenia Gkaliagkousi, Nikolaos Koletsos, Georgios Athanasopoulos, Xenophon Zabulis, Vasiliki Galanopoulou, Spyros Aslanidis, Stella Douma Tags: Original Research Source Type: research

Acute simvastatin treatment restores cerebral functional capillary density and attenuates angiotensin II ‐induced microcirculatory changes in a model of primary hypertension
Abstract ObjectiveWe investigated the acute effects of simvastatin on cerebral microvascular rarefaction and dysfunction in spontaneously hypertensive rats (SHRs). MethodsMale Wistar Kyoto rats (WKY) and SHRs were divided into 4 groups of 8 animals each: WKY‐CTL and SHR‐CTL, treated with 0.9% saline; and WKY+SIM and SHR+SIM, treated with simvastatin (30 mg/kg/day) for 3 days by gavage. Cerebral functional capillary density (FCD) was assessed by intravital fluorescence videomicroscopy. Microvascular cerebral blood flow (mCBF) before and after administration within the cranial window of angiotensin II (1 μM) was inves...
Source: Microcirculation - August 1, 2017 Category: Research Authors: Felipe Freitas, Vanessa Estato, Patricia Reis, Hugo C. Castro ‐Faria‐Neto, Vinícius Carvalho, Rafael Torres, Marcos A. Lessa, Eduardo Tibiriçá Tags: Original Research Source Type: research

Effect of direct cold atmospheric plasma (diCAP) on microcirculation of intact skin in a controlled mechanical environment
ConclusiondiCAP‐treatment of intact skin notably enhances microcirculation for a therapeutically relevant period. This effect is specific to the plasma treatment and not an effect of the applied pressure. Prolonged treatment durations lead to more pronounced effects.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 1, 2017 Category: Research Authors: Thomas Borchardt, Jennifer Ernst, Andreas Helmke, Murat Tanyeli, Arndt F. Schilling, Gunther Felmerer, Wolfgang Vi öl Tags: Original Research Source Type: research

Between ‐day reliability of local thermal hyperaemia in the forearm and index finger using single point laser‐Doppler flowmetry
ConclusionFor all sites, LTH reliability was acceptable for the timing, and for the initial peak and plateau using CVC or %CVC44°C.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 1, 2017 Category: Research Authors: Gregory W. McGarr, Gary J. Hodges, Stephen S. Cheung Tags: Original Research Source Type: research

Endothelial precursor cells stimulate pericyte ‐like coverage of bone marrow derived mesenchymal stem cells through PDGF‐BB induction, which is enhanced by substance‐P
ConclusionsBM‐EPCs along with SP promote the pericyte‐like coverage of BM‐MSCs on endothelial tubules possibly through the induction of PDGF‐BB.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - August 1, 2017 Category: Research Authors: Mingzi Zhang, Woosung Ahn, Sumin Kim, Hyun Sook Hong, Chengshi Quan, Youngsook Son Tags: Original Research Source Type: research

Hypoxia ‐enhanced adhesion of red blood cells in microscale flow
ConclusionsThe approach presented here enabled the control of oxygen tension in blood during microscale flow and the quantification of RBC adhesion in a cost‐efficient and patient‐specific manner. We identified a unique patient population in which RBCs showed enhanced adhesion in hypoxia in vitro. Clinical correlates suggest a more severe clinical phenotype in this subgroup. (Source: Microcirculation)
Source: Microcirculation - July 10, 2017 Category: Research Authors: Myeongseop Kim, Yunus Alapan, Anima Adhikari, Jane A. Little, Umut A. Gurkan Tags: ORIGINAL ARTICLE Source Type: research

Microfluidics Technologies and Approaches for Studying the Microcirculation
Abstract A challenge for basic and applied microvascular research is the lack of ex vivo experimental platforms that mimic the structural and functional complexity that is inherent to the microcirculation in living organisms. This Special Topic Issue highlights the emergence of microfluidic‐based approaches as tools for recapitulating physiologically relevant network architectures and hemodynamics to study biochemical and biomechanical mechanisms of microvascular function and adaptation. This collection of review and original research articles showcases the value of microfluidics in bridging the gap between in vivo and i...
Source: Microcirculation - July 10, 2017 Category: Research Authors: Walter L. Murfee, Shayn M. Peirce Tags: EDITORIAL Source Type: research

Issue Information
(Source: Microcirculation)
Source: Microcirculation - July 10, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research

The hypertension of hemophilia is associated with vascular remodeling in the joint
ConclusionsVascular remodeling in hemophilic joints is associated with hypertension and elevated blood pressures. Since hypertension is a grave risk factor for intracranial hemorrhage, a prominent cause of mortality in hemophilia patients, future studies are needed to address the causal pathways between vascular joint remodeling and blood pressure.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - June 19, 2017 Category: Research Authors: Richard FW Barnes, Thomas J Cramer, Tudor H Hughes, Annette von Drygalski Tags: Original Research Source Type: research

Lymph node effective vascular permeability and chemotherapy uptake
ConclusionsLymph node effective vascular permeability can be increased (~4‐fold) by VEGF‐A. However, no significant increase in chemotherapy uptake was measured by pre‐treatment with VEGF‐A.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - May 16, 2017 Category: Research Authors: Eelco FJ Meijer, Cedric Blatter, Ivy X Chen, Echoe Bouta, Dennis Jones, Ethel R Pereira, Keehoon Jung, Benjamin J. Vakoc, James W Baish, Timothy P Padera Tags: Original Research Source Type: research

Model ‐based inference from microvascular measurements: Combining experimental measurements and model predictions using a Bayesian probabilistic approach
ConclusionOur Bayesian probabilistic approach may be suitable for optimizing data acquisition and for analyzing and reporting large data sets acquired as part of microvascular imaging studies. (Source: Microcirculation)
Source: Microcirculation - May 15, 2017 Category: Research Authors: Peter M. Rasmussen, Amy F. Smith, Sava Sakad žić, David A. Boas, Axel R. Pries, Timothy W. Secomb, Leif Østergaard Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: Microcirculation)
Source: Microcirculation - May 15, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research

Estimating Blood Flow in Skeletal Muscle Arteriolar Trees Reconstructed from In Vivo Data Using the Fry Approach
ConclusionsWe have developed and validated a computational method that can accurately estimate RBC flow distribution in skeletal muscle arteriolar trees in the absence of complete boundary data.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - May 4, 2017 Category: Research Authors: Zahra Farid, Amani H. Saleem, Baraa K. Al ‐Khazraji, Dwayne N. Jackson, Daniel Goldman Tags: Original Research Source Type: research

Effects of Different Intensity Laser Acupuncture at Two Adjacent Same ‐meridian Acupoints on Nitric Oxide and Soluble Guanylate Cyclase Releases in Human
ConclusionsThis is the first evidence reporting that LA induced significant elevations of NO‐sGC releases over acupoints, the enhanced signal molecules contribute to local circulation, which improves the beneficial effects of the therapy.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - May 1, 2017 Category: Research Authors: Wan ‐Ling Jiang, Hua‐Jiang Wei, Zhou‐Yi Guo, Yi‐Rong Ni, Hong‐Qin Yang, Shu‐Sen Xie Tags: Original Article Source Type: research

Acute skin trauma induces hyperemia, but superficial papillary nutritive perfusion remains unchanged
ConclusionThe results indicate that skin nutritive papillary capillary function can be assessed by CAVM and DRS, but not with LDPM because of its dependence of the deep plexus perfusion.This article is protected by copyright. All rights reserved. (Source: Microcirculation)
Source: Microcirculation - May 1, 2017 Category: Research Authors: Liv Kristin Sundheim, Ane Halse Sporast øyl, Torjus Wester, Göran Salerud, Knut Kvernebo Tags: Original Research Source Type: research