Postmenopausal giant ovarian tumor: a rare case report and literature review
Conclusions The high incidence of severe complications should be carefully considered when huge ovarian tumors or tumors containing a large amount of tumor fluid in postmenopausal women are removed. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Case Report Source Type: research

Exercise training and vascular function in postmenopausal individuals: a systematic review and meta-analysis
Importance Cardiovascular disease (CVD) is a leading cause of morbidity and mortality for menopausal individuals. Flow-mediated dilation (FMD), a surrogate marker of CVD, improves with aerobic exercise training in healthy and nonhealthy cohorts. However, systematic evaluation and precise estimate of this effect for menopausal individuals are unknown. Objective We conducted a systematic review with meta-analysis to evaluate the influence of exercise training on FMD in postmenopausal individuals. Evidence Review Studies were identified from systematic search of major electronic databases (PubMed, ScienceDir...
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Review Article Source Type: research

Lifestyle for breast cancer risk reduction
Primary prevention is the most cost-effective long-term strategy for reducing breast cancer occurrence. Lifestyle education centered on the 2018 American Institute for Cancer Research Cancer Prevention Recommendations, offered as a package, should be a core component of routine patient visits. The key components of the recommendations include maintenance of a normal weight; following a low-fat, whole-food, plant-predominant diet rich in whole grains, fruit, and vegetables; regular physical activity; and alcohol avoidance. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Clinical Corner: NAMS Practice Pearl Source Type: research

Results of a pilot study of a cooling mattress pad to reduce vasomotor symptoms and improve sleep
Objective This single-arm pilot study was designed to generate pilot data on the use of a cooling mattress pad system on vasomotor symptoms (VMS; hot flashes and/or night sweats), self-assessed sleep, and daily hot flash interference among perimenopausal and postmenopausal women. Methods A total of 15 perimenopausal and postmenopausal women aged 45 to 59 years experiencing four or more VMS per day were recruited from the community. After completion of baseline questionnaires and a 2-week daily diary to confirm VMS eligibility, all women received a cooling mattress pad system to use at night for 8 weeks, during w...
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Brief Reports Source Type: research

Impact of the CBT-Meno protocol on menopause-specific beliefs, dysfunctional attitudes, and coping behaviors
Conclusions The CBT-Meno protocol is effective in improving menopause-related symptoms and a broader range of outcomes, including problematic beliefs about menopause, dysfunctional attitudes related to depression, and menopause-specific behaviors. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Prasterone in the treatment of mild to moderate urge incontinence: an observational study
Objective To assess the effects of prasterone compared with hyaluronic acid on symptoms of mild to moderate urinary urgency in women with genitourinary syndrome of menopause. Methods This is an observational prospective cohort study. A total of 58 postmenopausal women were enrolled (from December 2019 to May 2021). Overactive Bladder Screener questionnaire, Patient Global Impression of Improvement questionnaire, International Consultation on Incontinence Questionnaire–Short Form, and International Quality of Life questionnaire were used. Results Fifty-eight women, 29 (50%) and 29 (50%), were treated wit...
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Clinicopathological features of endometrial lesions in asymptomatic postmenopausal women with thickened endometrium
Objective To analyze the clinical and pathological features of asymptomatic postmenopausal women with an incidentally detected increase in endometrial thickness (ET) by transvaginal ultrasound examination and discuss the cutoff value of ET for the timely discovery of endometrial malignancy. Methods This was a retrospective study of postmenopausal women with asymptomatic thickened endometrium (greater than or equal to 5 mm) screened by transvaginal ultrasound who were referred to the gynecology department at Xuanwu Hospital between January 2018 and March 2021. Data on participant demographics, clinical characteri...
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Serum total bilirubin and new-onset hypertension in perimenopausal women: a cross-sectional study
Conclusions In perimenopause, TBIL was inversely associated with diastolic blood pressure and new-onset hypertension, diagnosed using 24-hour ambulatory blood pressure monitoring. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Association of dietary intake of n-3 polyunsaturated fatty acids with breast cancer risk in pre- and postmenopausal Chinese women
Conclusions High intake of n-3 PUFAs and n-3 PUFA subtypes was associated with a lower risk of breast cancer, especially among premenopausal women and women with ER+ and/or PR+ subtype breast cancer. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Barriers to surgical menopause counseling in gynecologic cancers: a quantitative and qualitative study of patients and providers
Conclusions Younger age at surgery increased odds of receiving surgical menopause counseling. Gynecologic cancer patients experienced significant menopause-related disturbances. Improved understanding of patient and provider preferences and greater emphases on surgical menopause and survivorship will improve care for gynecologic oncology patients. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Correlation between plasma sphingosine-1-phosphate and the occurrence and severity of coronary heart disease in postmenopausal women
Objective Sphingosine-1-phosphate (S1P) is a bioactive sphingosine with antiatherosclerotic effects. The incidence of coronary heart disease (CHD) increases significantly among women after menopause. We explored the relationship between plasma S1P levels and the occurrence and severity of CHD in postmenopausal women. Methods Postmenopausal women admitted to our hospital for coronary angiography because of chest pain–like symptoms were included in our study. By 1:1 age matching (age difference ≤5 y), 166 women in the CHD group and control group were enrolled. The plasma S1P concentration was determined, and t...
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Lipoprotein subfractions and subclinical vascular health in middle aged women: does menopause status matter?
Conclusions Carotid intimal medial thickening is positively and independently associated with small- and medium-sized LDL particles after menopause. Monitoring levels of specific lipoprotein fractions may have value in identifying midlife women at risk for developing atherosclerotic vascular disease. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Uterine arcuate artery calcification as a potential marker of cardiovascular risk—a preliminary study
Conclusions The presence of UMC has been identified as an independent predictive factor for atherosclerotic risk. Accordingly, considering UMC as an atherosclerotic cardiovascular risk factor may provide an opportunity to identify cardiovascular disease in asymptomatic postmenopausal women. When UMC is detected, women should be assessed for cardiovascular risk. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

The longitudinal relation of inflammation to incidence of vasomotor symptoms
Conclusions Our results showed no significant association of the proinflammatory biomarkers, hs-CRP or IL-6, either concurrently or with subsequent incident VMS, indicating that inflammation was unlikely to be a risk factor for VMS. Thus, clinical treatments directed at reducing inflammation would be unlikely to reduce the occurrence of VMS. (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Original Studies Source Type: research

A new tool in the prediction of cardiovascular disease? Perhaps
No abstract available (Source: Menopause)
Source: Menopause - July 30, 2022 Category: OBGYN Tags: Editorials Source Type: research