Explaining the Potential Role of Hormone Replacement Therapy in Covid-19 Infection Among Postmenopausal Women. Reply
No abstract available (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Letters to the Editor Source Type: research

Explaining the Potential Beneficial Roles of Hormone Replacement Therapy in COVID-19 Infection Among Postmenopausal Women.
No abstract available (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Letters to the Editor Source Type: research

Different regimens of menopausal hormone therapy for improving sleep quality: a systematic review and meta-analysis
Importance: Long-term sleep disturbances in menopausal women are closely related to cardiovascular disorders, metabolic disorders, and cognitive impairment. At present, hormone therapy (HT) is a standard treatment for menopausal symptoms. However, it remains unclear whether HT can improve sleep quality. Objective: We did a systematic review and meta-analysis to assess the effects of different HT regimens on menopausal sleep quality. Evidence Review: We systematically searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, PsycINFO, CINAHL, and Web of Science for randomized controlled...
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Review Articles Source Type: research

Efficacy of interventions to manage sexual dysfunction in women with cancer: a systematic review
Conclusions and Relevance: The most reliable evidence for improvement was from a study of DHEA vaginal gel, but in general, gels or creams were useful in reducing dyspareunia. Pharmacological, psychoeducational, laser therapy, and multimodal approaches demonstrated potential in managing cancer-related sexual issues, but most were small in size (10-70 participants), with moderate to high risk of bias. Therefore, large-scale, double-blind, RCTs with long-period follow-up, and at low risk of bias are needed to show efficacy for these interventions. Video Summary:http://links.lww.com/MENO/A912. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Review Articles Source Type: research

Update on migraine management
Migraine is a highly prevalent disorder in women associated with significant disability. Yet it remains underdiagnosed and undertreated. Recent advances in our understanding of the pathophysiology of migraine, including the role of calcitonin gene-related peptide, has led to the development of new targeted migraine therapies. It is important for all healthcare professionals caring for women to be familiar with the diagnostic criteria for migraine and for them to follow a stepwise approach to management of acute and chronic migraine that comprises biobehavioral and pharmacologic management, particularly the more recently ap...
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Clinical Corner: NAMS Practice Pearl Source Type: research

A report on pharmacists with the NCMP credential
Conclusions: Pharmacists find the NCMP credential to be valuable. Although pharmacists are engaged in counseling and recommendations, they desire prescriptive authority related to menopause care. Future studies should explore the various pharmacist care models and evaluate the impact of pharmacist care on organizational operations and patient outcomes. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Mediation effect of body mass index on the association between age at menopause and type 2 diabetes mellitus in postmenopausal Chinese women
This study aimed to examine the association between age at menopause and type 2 diabetes mellitus (T2DM), and whether this association is mediated by body mass index (BMI) in postmenopausal Chinese women. Methods: This cross-sectional study enrolled 4,279 postmenopausal women. Binary logistic regression was used to estimate the association between age at menopause and T2DM. A multiple linear regression model was used to evaluate the relationships between age at menopause and fasting plasma glucose (FPG), 2-hour postprandial blood glucose (2hPBG), homeostasis model assessment for insulin resistance (HOMA)-IR, and HOM...
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

The effect of micronized progesterone and medroxyprogesterone acetate in combination with transdermal estradiol on hemostatic biomarkers in postmenopausal women diagnosed with POI and early menopause: a randomized trial
Conclusion: Fluctuations in traditional hemostatic biomarkers were not reproduced by parallel changes in thrombin generation parameters that remained neutral in both groups compared with baseline. The absence of statistically significant changes in thrombin generation for the first 3-months of hormone therapy use is reassuring and would suggest a neutral effect of both progestogens on the global coagulation assay. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Prognostic value of arterial stiffness in menopausal women
This study aimed to verify the prognostic value of arterial stiffness in menopausal women. Methods: We retrospectively analyzed 2,917 menopausal women (age>55y) without overt cardiovascular disease who underwent brachial-ankle pulse wave velocity measurement. The primary endpoint was a composite of clinical events, including all-cause death, nonfatal myocardial infarction, coronary revascularization, and stroke, hereafter referred to as major adverse cardiovascular events. Propensity score matching and inverse probability-treatment weighting analysis were used to balance differences in baseline participant character...
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

The association of age at natural menopause with pre- to postmenopausal changes in left ventricular structure and function: the Coronary Artery Risk Development in Young Adults (CARDIA) study
Conclusion: In this study, premenopausal CVD risk factors attenuated the association of ANM with changes in LV structure parameters. These data suggest that premenopausal CVD risk factors may predispose women to elevated future CVD risk more than ovarian aging. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Prevalence, severity, and associated factors in women in East Asia with moderate-to-severe vasomotor symptoms associated with menopause
Conclusions: Vasomotor symptoms associated with menopause affected =80% of women aged 40 to 65 years. A substantial proportion of women are unsuitable for, or choose not to take, menopausal hormone therapy, resulting in an unmet need for nonhormonal treatment options. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

The effect of music therapy on menopausal symptoms and depression: a randomized-controlled study
Conclusions: There was a significant decrease of posttest BDI scores of the women in the music group but not in the control group. Listening to music can help reduce depression levels and symptoms of menopause in postmenopausal women. Music could be used as a nonpharmacological therapeutic option in nursing care. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

A 16-week multicomponent exercise training program improves menopause-related symptoms in middle-aged women. The FLAMENCO project randomized control trial
Conclusions: A 16-week multicomponent physical exercise program showed a positive effect on menopause- related symptoms especially in couple relationships, psychological state, and VMS, among 45 to 60 year old women. (Source: Menopause)
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Blood pressure control and glaucoma risk in postmenopausal women: an analysis from the Women's Health Initiative
Objective: Individuals with elevated systolic blood pressure (BP) or low diastolic BP, whether or not on antihypertensive treatment, may be at higher risk for developing glaucoma. We aimed to investigate BP levels in relation to glaucoma risk in a large cohort of postmenopausal women. Methods: Prospective follow-up of 101,447 postmenopausal women without prior history of glaucoma enrolled in the Women's Health Initiative Study. BP was measured in-clinic at baseline and after 3 years using standardized procedures. Antihypertensive medication use was determined by drug inventory at baseline and year 3. Women sel...
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research

Avoidable bilateral salpingo-oophorectomy at hysterectomy: a large retrospective study
Objectives: Evaluate the proportion of justified bilateral salpingo-oophorectomy (BSO) at hysterectomy, based on pathologic diagnosis, and determine prevalence of avoidable BSO based on pre- and intraoperative considerations and pathologic diagnosis. Methods: Retrospective review of hysterectomies at seven Ontario, Canada hospitals from 2016 to 2019. Surgeries completed by oncologists or for invasive placentation were excluded. Patient, case, and surgeon characteristics were recorded along with pathologic diagnoses. Avoidable BSO criteria were: preoperative diagnosis of cervical dysplasia or benign diagnosis oth...
Source: Menopause - May 1, 2022 Category: OBGYN Tags: Original Studies Source Type: research