Log in to search using one of your social media accounts:

 

Meaningful weight loss in obese postmenopausal women: a pilot study of high-intensity interval training and wearable technology
Objective: Postmenopausal women cite lack of time as their primary barrier to exercise and related weight control behaviors. The purpose of this study was to address this barrier via testing the feasibility and initial outcomes of a short-duration/high-intensity interval training (HIIT)-based weight loss program among obese postmenopausal women, with descriptive comparison to an endurance-focused exercise program. Methods: A 16-week behavioral program incorporated (1) HIIT to limit time necessary to produce health benefits of exercise, and (2) wearable activity sensors to facilitate self-monitoring exercise. Participa...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Brief Report Source Type: research

Negative correlation of high-density lipoprotein-cholesterol and bone mineral density in postmenopausal Iranian women with vitamin D deficiency
Objective: The aim of the study was to investigate the association between high-density lipoprotein (HDL) and bone status taking into account serum vitamin D levels in postmenopausal Iranian women. Methods: During January 2015 and February 2016, a total of 488 postmenopausal Iranian women participated in this cross-sectional study, all of whom were not taking osteoporosis medication and were not suffering from any chronic disorder. Dual X-ray absorptiometry was used to assess bone mineral density (BMD) of the total hip, femoral neck, and lumbar vertebrae (L2-L4). Each person was categorized based on the World Health O...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women
Conclusion: Genetic variants associated with earlier age-at-natural menopause are associated with increased cardiovascular disease risk in women, but not men, suggesting sex-specific genetic effects on cardiovascular disease risk. (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Cross-cultural validation of the Modified Falls Efficacy Scale in Serbian community-dwelling women at risk for osteoporotic fracture
Objective: Cross-cultural validation of the Serbian version of the Modified Falls Efficacy Scale (MFES). Methods: This cross-sectional study involved 257 women aged 65 years and above who were referred for dual-energy x-ray absorptiometry examination at the Railway Healthcare Institute in Belgrade, Serbia, between January and April 2016. Data collection comprised of a sociodemographic questionnaire and Geriatric Depression Scale-Short Form (GDS-SF) questionnaire, and data related to fractures, level of physical activity, use of medications that can increase the risk of falls, and frequency of falls in the past 12 mont...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Associations of consuming specific fruit and vegetable subgroups with LDL-C status in early postmenopausal Chinese women
Conclusions: A daily consumption of vegetables equivalent to about four servings or more might be beneficial for LDL-C control in early Chinese postmenopausal women. In particular, darkgreen leafy vegetables, as well as corn and tubers, deserve greater advocacy for their ability to improve lipid profiles and hence cardiovascular health. (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Vaginal health of postmenopausal women on nutraceutical containing equol
Objective: The aim of the study was to evaluate the effects of nutraceuticals containing equol on vaginal health of postmenopausal women with vulvovaginal symptoms and dyspareunia. Methods: One hundred twenty-six natural postmenopausal women on +1b +1c (2 and 3-6 y after the final menstrual period, respectively) of the Stages of Reproductive Aging Workshop were enrolled in a nonrandomized trial. Of these, 72 women accepted to use nutraceutical (group A). The remaining 54 women refused the treatment and participated as the control group (group B). Group A was prescribed one tablet daily to take orally, for 8 months. Al...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Age at natural menopause in Koreans: secular trends and influences thereon
Objectives: Age at natural menopause (ANM) has become an important health issue in older women. We explored secular trends in ANM in Korea during the past decade, and defined factors predicting ANM. Methods: A total of 12,761 naturally menopausal women were selected from the 2001 to 2014 data of the Korea National Health and Nutrition Examination Survey, stages II to VI. The participants were divided into four groups based on 5-year ANM categories: (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Risk factors associated with intensity of climacteric symptoms in Brazilian middle-aged women: a population-based household survey
Objective: To determine the factors associated with the intensity of climacteric somatovegetative, psychological, and urogenital symptoms among middle-aged women in the Metropolitan Region of Campinas, Brazil. Methods: A cross-sectional population-based household survey was conducted with 749 women aged 45 to 60 years. The dependent variable was the intensity of menopausal symptoms assessed using the Menopause Rating Scale. The independent variables were sociodemographic data, health-related habits and problems, self-perception of health, and gynecological background. Results: The mean age of the women was 52.5 &...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Menopause improves the predictive value of common cardiovascular risk scores in women with premature coronary artery disease
Conclusion: Adding the early menopausal period may significantly improve the predictive value of the 10-year Atherosclerotic Cardiovascular Disease risk score and the Systematic COronary Risk Evaluation model in women with premature coronary artery disease. (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Age-related changes in luteal dynamics: preliminary associations with antral follicular dynamics and hormone production during the human menstrual cycle
Objective: The aim of the study was to test the hypothesis that the development of luteal phase dominant follicles (LPDFs) as women age is associated with abnormal luteal function. Methods: Luteal and antral follicle diameter were quantified in ovulatory women of midreproductive age (MRA; 18-35 y; n = 9) and advanced reproductive age (ARA; 45-55 y; n = 16) every 1 to 3 days during one complete interovulatory interval. Blood was drawn at each visit and assayed for progesterone, estradiol, inhibin A, follicle-stimulating hormone, and luteinizing hormone. Luteal diameter and hormone profiles were compared within ...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Association of vasomotor symptoms and sleep apnea risk in midlife women
Objective: The aim of the study was to determine the association between self-reported vasomotor symptoms (VMS) and obstructive sleep apnea (OSA) risk. Methods: The STOP-BANG to evaluate OSA and Menopause Rating Scale (MRS) were administered to 2,935 women seen in the Women's Health Clinic at Mayo Clinic in Rochester, MN, between May 2015 and December 2016. Of these, 1,691 women were included in the analysis. Total MRS and VMS ratings were compared using logistic regression, with age, smoking, and body mass index (BMI) included as covariates between women at intermediate/high risk versus low risk for OSA. Results: ...
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

The dynamics of stress and fatigue across menopause: attractors, coupling, and resilience
Conclusions: Results are suggestive of general dysregulation via disruptions to coupling relationships of stress and fatigue across the MT. Findings support a holistic approach to understanding symptoms and supporting women during the MT. (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Increased cardiac and stroke death risk in the first year after discontinuation of postmenopausal hormone therapy
Conclusions: Discontinuation of postmenopausal HT may be associated with increased risk of cardiac and stroke death in the first posttreatment year. Further investigation is required to evaluate causality of the observed associations. (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Trauma exposure and endothelial function among midlife women
Conclusions: A greater number of traumatic exposures were associated with poorer endothelial function. Relations were not explained by demographics, CVD risk factors, mood/anxiety, or a by history of childhood abuse. Women with greater exposure to trauma over life maybe at elevated CVD risk. (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Cardiovascular risk after withdrawal of hormone therapy
No abstract available (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Editorials Source Type: research

Novel risk factor for cardiovascular disease in women: history of trauma
No abstract available (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Editorials Source Type: research

Changes in an office practice of menopause in the last 25 years
No abstract available (Source: Menopause)
Source: Menopause - March 23, 2018 Category: OBGYN Tags: Editorials Source Type: research

Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment: Erratum
No abstract available (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Erratum Source Type: research

In Reply
No abstract available (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

To the Editor
No abstract available (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Effects of multicomponent training on lean and bone mass in postmenopausal and older women: a systematic review
Conclusions:Further studies are needed to identify the optimal multicomponent training protocols, specifically the training loads that will improve lean and bone mass at different anatomical locations, in postmenopausal and older women. Objective: The purpose of this systematic review was to update and examine to what extent multicomponent training interventions could improve lean and bone mass at different anatomical regions of the body in postmenopausal and older women. Methods: A computerized literature search was performed in the following online databases: PubMed MEDLINE, Cochrane, and Web of Knowledge. The sea...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Review Article Source Type: research

Screening mammography for average-risk women
This Practice Pearl describes an approach to screening mammography for average-risk women that encourages the use of shared decision-making that addresses benefits (early diagnosis and decreased mortality) and potential harms (false positives and overdiagnosis/overtreatment) in determining screening mammography initiation, frequency, and duration for women at average risk of breast cancer. (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Clinical Corner: NAMS Practice Pearl Source Type: research

The effects of supplemental vitamin E on hematological parameters in a rat model of ovarian hormone deficiency
Conclusion:These findings suggest that vitamin E in the form of α-tocopherol acetate may provide protection against ovarian hormone deficiency-associated adverse changes in hematological parameters. Objective: Menopause is associated with adverse changes in hematological parameters. Although the antioxidative and anti-inflammatory properties of vitamin E have been previously demonstrated, the effects of vitamin E on hematopoietic parameters are not well-documented. This study investigated the effects of supplemental vitamin E on hematological parameters in a rat model of ovarian hormone deficiency. Methods: Tw...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to obesity in Chinese postmenopausal women
AbstractObjective:We conducted a case-control study to investigate the associations of functional single-nucleotide polymorphisms in the purinergic P2X7 receptor (P2X7R) gene (rs2393799, rs7958311, rs1718119, rs2230911, and rs3751143) with obesity and overweight in a population of Chinese postmenopausal women.Methods:Our study included 180 obese women, 179 overweight women, and 204 controls. All participants were genotyped at the P2X7R rs2393799, rs7958311, rs1718119, rs2230911, and rs3751143 loci via allele-specific polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism procedures. The relationsh...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Low bone mineral density in middle-aged women: a red flag for sarcopenia
This study evaluated whether low bone density, a condition related to aging, is associated with low muscle mass, a surrogate for sarcopenia, and whether it could be used as a marker of the condition.Methods:We studied 483 women aged 35 to 69 years old who appeared healthy and attended a preventive gynecological examination. Dual-energy X-ray absorptiometry was used to measure bone mineral density (BMD) and regional body composition. BMD was assessed using the T-score. Low appendicular lean mass (aLM) adjusted by height (aLM index) was defined according to Baumgartner et al ( (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Body iodine status in women with postmenopausal osteoporosis
AbstractObjective:Postmenopausal osteoporosis is a frequent cause of morbidity and can negatively impact life expectancy; iodine is an essential element for bone mineralization, and iodine deficiency is frequently observed. The aim of the present study was to understand the connection between postmenopausal osteoporosis and the level of iodine in the body.Methods:A total of 132 participants were divided into three groups: group 1 consisted of healthy postmenopausal women (n = 34), group 2 comprised osteopenic women (n = 38), and group 3 included women with postmenopausal osteoporosis (n = 60). The three groups ...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Depressive symptoms screening in postmenopausal women with symptomatic pelvic organ prolapse
This study aimed to investigate the prevalence of depressive symptoms in postmenopausal women with symptomatic pelvic organ prolapse (POP) and to identify the factors associated with depressive symptoms in this population.Methods:We conducted a cross-sectional study involving postmenopausal women with symptomatic POP who visited the Center of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, between July 2016 and March 2017. We collected data pertaining to participants’ sociodemographic characteristics and medical histories. The participants enrolled in the study were evaluated by POP quantif...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Is BMI a valid measure of obesity in postmenopausal women?
Conclusions:Results demonstrate that a BMI cut-point of 30 kg/m2 does not appear to be an appropriate indicator of true obesity status in postmenopausal women. Empirical estimates of the validity of BMI from this study may be used by other investigators to account for BMI-related misclassification in older women. Objective: Body mass index (BMI) is a widely used indicator of obesity status in clinical settings and population health research. However, there are concerns about the validity of BMI as a measure of obesity in postmenopausal women. Unlike BMI, which is an indirect measure of obesity and does not distinguis...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Effect of 2 years of endurance and high-impact training on preventing osteoporosis in postmenopausal women: randomized clinical trial
Conclusions:Calcium plus vitamin D supplementation combined with specifically oriented exercises had a higher impact in the femoral neck than walking at an intense pace. As there were no differences at the lumbar spine level, the results were, however, inconclusive concerning which type of exercise was the most convenient. Importantly, the fact that the T-scores did not decrease after 2 years supports the belief that both proposed interventions can be conveniently used to prevent osteoporosis in postmenopausal women. A trial with a larger sample size would provide consistency to the findings and is warranted given the poss...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Concentration range of serum sex steroids in normal postmenopausal women and those with diagnosis of vulvovaginal atrophy
AbstractObjective:The aim of the study was to determine the range of serum sex-related steroids in normal postmenopausal women and in women of the same age with a diagnosis of vulvovaginal atrophy (VVA).Methods:Validated mass spectrometry-based assays coupled to gas or liquid chromatography were used over a 10-year period for steroid measurements. Serum samples were obtained in up to 1,512 women aged 55 to 65 years.Results:Serum estrone sulfate (E1S) and androsterone glucuronide (ADT-G), the main metabolites of estrogens and androgens, respectively, were 16.9% (P = 0.005) and 16.1% (P = 0.001) higher in women not d...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Changes in sexual function among midlife women: “I’m older… and I’m wiser”
Conclusions:In this qualitative study, women described experiencing both positive and negative changes in sexual function during midlife. When negative changes occurred, women often adapted behaviorally and psychologically. Providers should recognize that each woman's experience is unique and nuanced, and they should provide tailored care regarding sexual function at midlife. Objective: Women experience a variety of changes at midlife that may affect sexual function. Qualitative research approaches can allow a deeper understanding of women's experiences. We conducted 20 individual interviews and three focus groups amon...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Initial investigation into the optimal dose ratio of conjugated estrogens and bazedoxifene: a double-blind, randomized, placebo-controlled phase 2 dose-finding study
AbstractObjective:The aim of the study was to explore dose-related endometrial effects of conjugated estrogens/bazedoxifene (CE/BZA).Methods:In this randomized, double-blind, phase 2 study, 408 nonhysterectomized, symptomatic (with hot flushes [HFs]) postmenopausal women received ≥1 dose of CE 0.3 or 0.625 mg alone or with BZA 5, 10, or 20 mg/d; placebo; BZA 5 mg/d alone; or CE 0.625 mg with medroxyprogesterone acetate 2.5 mg/d for 84 days. The primary outcome was endometrial thickness on transvaginal ultrasound. HF frequency and severity based on diaries were key secondary outcomes.Results:CE 0.625 mg alone...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Age at natural menopause and its associated factors in Canada: cross-sectional analyses from the Canadian Longitudinal Study on Aging
Conclusions:These findings provide a national estimate of ANM in Canada and show the importance of lifestyle factors and health conditions in determining menopausal age. These factors might help in risk assessment, prevention and early management of chronic disease risk during the menopausal transition. Background: Early onset of menopause is associated with long-term disease and higher mortality risks. Research suggests that age at natural menopause (ANM) varies across populations. Little is known about factors that affect ANM in Canadian women. Objective: This study aims to estimate the median ANM and examine fact...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Sexual activity and vaginal symptoms in the postintervention phase of the Women's Health Initiative Hormone Therapy Trials
AbstractObjective:To assess the impact of discontinuing oral hormone therapy (HT) on sexual activity, vaginal symptoms, and sexual activity components among participants in the estrogen-progestin therapy (EPT) and estrogen therapy (ET) trial of the Women's Health Initiative.Methods:Surveys were sent postintervention to those who were still taking study pills and agreed to continue in the study when the trials were stopped. Comparisons between former HT and placebo users were accomplished with chi-square tests for categorical variables and t tests for continuous variables.Results:In all, 13,902 women with mean age at survey...
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Do social determinants of health make a difference in the age at natural menopause in Canada?
No abstract available (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Editorials Source Type: research

The Women's Health Initiative: addressing vaginal and sexual health
No abstract available (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Editorials Source Type: research

Ultrasound in menopause: a look back
No abstract available (Source: Menopause)
Source: Menopause - February 21, 2018 Category: OBGYN Tags: Editorials Source Type: research

Response to letter to editor
No abstract available (Source: Menopause)
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Letter to the Editor
No abstract available (Source: Menopause)
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Letters to the Editor Source Type: research

Postmenopausal choriocarcinoma: a rare case report and review of the literature
We report a rare case of a postmenopausal woman with choriocarcinoma. The 61-year-old patient presented with irregular vaginal bleeding, 11 years after menopause and 30 years after the birth of the last child.Results:Radiological investigation found a 3-cm mass on the lower left part of the vaginal wall, and also bilateral lung nodules. Gynecological examination found 3-4 cm blue and purple nodules in the lower left part of the vaginal wall. Her serum CA125 and serum β-hCG levels were 10.2 and 9273.9 mIU/mL, respectively. The early diagnosis was a choriocarcinoma, and combination chemotherapy (etoposide, kengsheng...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Case Report Source Type: research

Prevalence of sexual symptoms in relation to menopause in women in Asia: a systematic review
Conclusions:The available data, despite its limitations, suggests that after menopause, lowered sexual desire and vulvovaginal atrophy symptoms, including dryness, irritation, soreness, and dyspareunia, are common in women in Asia. The extent to which such symptoms cause women distress is not known. Studies of representative samples of premenopausal, perimenopausal, and postmenopausal women that use robustly translated and culturally appropriate validated questionnaires, and that collect detailed demographic data are still needed to determine the prevalence of sexual symptoms in relation to menopause in women in Asia. Ob...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Review Article Source Type: research

Clinical trials in menopause
Conclusions:The available literature suggests that HT is a viable option for the primary prevention of cardiovascular disease in postmenopausal women. Newer trials will likely verify this assessment. If this is enough to change clinical practice, however, remains to be seen given the general fear of HT by many with prescriptive authority, and also the women in our care. Objective: Clinical trials in menopause have undergone much scrutiny over the years. This has led to significant shifts in the treatment of symptomatic menopause and a substantial impact on women. We aim to delineate the key studies contributing to this...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Clinical Corner: Invited Review Source Type: research

Resistance training reduces inflammation and fatigue and improves physical function in older breast cancer survivors
AbstractObjective:Resistance training (RT) reduces fatigue and improves physical function and quality of life (QOL) in breast cancer survivors (BCS). This may be related to reductions in systemic and tissue-specific inflammation. This pilot study examines the hypothesis that RT induces changes in systemic and tissue-specific inflammation that contribute to improvements in physical and behavioral function in postmenopausal BCS.Methods:Eleven BCS (60 ± 2 years old, body mass index 30 ± 1 kg/m2, mean ± SEM) underwent assessments of fatigue (Piper Fatigue Scale), physical function, QOL (SF-36...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Brief Report Source Type: research

Orthosiphon stamineus (Misai Kucing) ameliorated postmenopausal osteoporosis in rat model
This study investigated the potential use of OS leaf extracts to ameliorate osteoporosis in ovariectomized rats.Methods:Fifty-six female Sprague-Dawley rats were randomly allocated into eight groups (n = 7): SHAM (healthy sham control); OVX (ovarietomized) nontreated rats (negative control); OVX + Remifemin (100 mg/kg body weight), and 2% green tea extract (positive controls); OVX + OS 50% ethanolic and aqueous extracts, both at either 150 or 300 mg/kg. After 16 weeks, the rats’ bones and blood were evaluated for osteoporosis indicators (protein and mRNA expressions), micro-computed tomography for bon...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Associations among circulating colony-stimulating factor-1, estrogen, and bone mineral density in postmenopausal women: results from a randomized placebo-controlled trial
Conclusions:This study did not demonstrate a meaningful relationship between circulating levels of CSF-1 and bone mineral density in either the placebo group or estrogen-treated group. Although CSF-1 is required for osteoclastic bone resorption, our data suggest that circulating levels of the cytokine may not reflect this process. Objective: This study addresses the relationship between circulating levels of colony-stimulating factor 1 (CSF-1) and rates of postmenopausal bone loss. The purpose was to test the hypothesis that CSF-1 levels would correlate with the rate of bone loss in estrogen-deficient woman. We further...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Pharmacokinetics and safety profile of single-dose administration of an estrogen receptor β-selective phytoestrogenic (phytoSERM) formulation in perimenopausal and postmenopausal women
Conclusions:A single-dose oral administration of the phytoSERM formulation was well-tolerated and did not elicit any adverse events. It was rapidly absorbed, reached high plasma concentrations, and showed a linear dose-concentration response in its pharmacokinetics. These findings are consistent with previously reported parameters for each parent compound (Clinicaltrials.gov NCT01723917). Objective: Selected estrogen receptor β-selective phytoestrogen (phytoSERM), a preparation of genistein, daidzein, and S-equol, has an 83-fold selective affinity for estrogen receptor (ER) β, and may promote neuronal surviva...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Understanding the complex relationships underlying hot flashes: a Bayesian network approach
Conclusions:These models can serve as a guide for design of studies into the causal network underlying hot flashes. Objective: The mechanism underlying hot flashes is not well-understood, primarily because of complex relationships between and among hot flashes and their risk factors. Methods: We explored those relationships using a Bayesian network approach based on a 2006 to 2015 cohort study of hot flashes among 776 female residents, 45 to 54 years old, in the Baltimore area. Bayesian networks were fit for each outcome (current hot flashes, hot flashes before the end of the study, hot flash severity, hot flash fre...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Functional capacity depends on lower limb muscle strength rather than on abdominal obesity in active postmenopausal women
Conclusions:Our results demonstrate an association between abdominal obesity and FC in active postmenopausal women and that the strongest association and the best predictor of FC was lower limb muscle strength. Thus, active postmenopausal women with abdominal obesity may not necessarily have a reduced FC if lower limb muscle strength is preserved. Objective: An association has been found between abdominal obesity and functional capacity (FC) in the literature where waist circumference has been used to infer abdominal obesity. However, most studies focused on evaluating predictors of FC and functional disabilities only ...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Effects of menopause and high-intensity training on insulin sensitivity and muscle metabolism
AbstractObjective:To investigate peripheral insulin sensitivity and skeletal muscle glucose metabolism in premenopausal and postmenopausal women, and evaluate whether exercise training benefits are maintained after menopause.Methods:Sedentary, healthy, normal-weight, late premenopausal (n = 21), and early postmenopausal (n = 20) women were included in a 3-month high-intensity exercise training intervention. Body composition was assessed by magnetic resonance imaging and dual-energy x-ray absorptiometry, whole body glucose disposal rate (GDR) by hyperinsulinemic euglycemic clamp (40 mU/m2/min), and femoral muscle ...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research

Is outpatient hysteroscopy accurate for the diagnosis of endometrial pathology among perimenopausal and postmenopausal women?
Conclusions:Outpatient hysteroscopy is an adequate and reliable tool for the evaluation of benign pathology in the uterine cavity. Visual findings may not suffice, and directed biopsies may be required to improve diagnostic accuracy. Objective: To assess the histological and visual accuracy of outpatient hysteroscopy. Methods: This was a retrospective analysis of all women referred to a tertiary center outpatient hysteroscopy clinic between March 2011 and October 2016 for the following indications: postmenopausal bleeding, suspected polyp, and/or thick endometrium. Histological accuracy was evaluated by comparing sp...
Source: Menopause - January 18, 2018 Category: OBGYN Tags: Original Articles Source Type: research