Menopausal hormone therapy and risk of incident hypertension: role of the route of estrogen administration and progestogens in the E3N cohort
Conclusions: MHT was associated with a modest but significant increased risk of incident hypertension, especially when using oral estrogen in combination with a progestogen such as pregnane and norpregnane derivatives. Surveillance of blood pressure should be added to the medical surveillance of MHT users. Video Summary:http://links.lww.com/MENO/A802. (Source: Menopause)
Source: Menopause - November 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

Fibroids after menopause: they never stop growing
No abstract available (Source: Menopause)
Source: Menopause - November 1, 2021 Category: OBGYN Tags: Editorials Source Type: research

Menopausal hormone therapy and hypertension: minimizing risk
No abstract available (Source: Menopause)
Source: Menopause - November 1, 2021 Category: OBGYN Tags: Editorials Source Type: research

Influencing factors on women's attitudes toward menopause: a systematic review
Conclusion and relevance: The findings showed that menopausal stage, menopausal symptoms, and psychological and socioeconomic status can influence the attitude of women toward menopause. Therefore, these factors should be considered in interventions that aim to improve women's attitudes toward menopause. (Source: Menopause)
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Review Article Source Type: research

Menopause preparedness: perspectives for patient, provider, and policymaker consideration
Conclusions: To improve care and quality of life for individuals during the menopause transition and after menopause, the working group recommends developing a more standardized approach to menopause preparedness that includes education for both patients and providers, as well as considering policy solutions to address regulatory barriers to care. Providers also need to factor in the diverse needs of individuals experiencing menopause in the development of their personalized care. (Source: Menopause)
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Personal Perspective Source Type: research

Different cutoff points to diagnose low muscle mass and prediction of osteoporosis in postmenopausal women
This study aimed to verify which of the different cutoff points of low muscle mass (LMM) based on appendicular lean mass (ALM) is associated with osteoporosis in postmenopausal women (PMW). Methods: Cross-sectional study. PMW (n = 355) were classified for the presence of osteoporosis (score (Source: Menopause)
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Brief Reports Source Type: research

Impact of sleep disturbances on employment and work productivity among midlife women in the US SWAN database: a brief report
Conclusions: New-onset sleep problems in midlife women are associated with significant increases in risk of unemployment and ∼$2 billion/yr in lost productivity nationwide. Video Summary:http://links.lww.com/MENO/A798. (Source: Menopause)
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Brief Reports Source Type: research

Associations between menopause, cardiac remodeling, and diastolic function: the CARDIA study
Objectives: Heart failure with preserved ejection fraction (HFpEF) affects more women than men. Menopause may influence HFpEF development in women. We assessed cross-sectional and longitudinal associations between menopause and echocardiographic measures of left ventricular (LV) function and cardiac remodeling. Methods: We studied 1,723 women with available echo data from at least two of: year 5 (Y5) (1990-1991), Y25 (2010-2011), or Y30 (2015-2016) in the Coronary Artery Risk Development in Young Adults study. Cardiac structure and function were measured using 2D and Doppler echocardiography. Cross-sectional ass...
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

Association between higher serum uric acid levels within the normal physiological range and changes of lumbar spine bone mineral density in healthy Chinese postmenopausal women: a longitudinal follow-up study
Objectives: The aim of this study was to investigate whether higher serum uric acid (SUA) levels within the physiological range were associated with changes in lumbar spine bone mineral density (LBMD) in postmenopausal women without existing lumbar spine osteoporosis after a longitudinal follow-up of 3.09 years, and to further confirm the relationship between SUA and bone mineral density (BMD) in other sites such as femoral neck, total hip, and trochanter at follow-up. Methods: A longitudinal study of 175 healthy postmenopausal women without osteoporosis was conducted in Shenyang, China. BMD of the lumbar spin...
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

The Women's Study for the Alleviation of Vasomotor Symptoms (WAVS): a randomized, controlled trial of a plant-based diet and whole soybeans for postmenopausal women
This study aimed to assess the effects of the combination of a low-fat plant-based diet and soybeans on the frequency and severity of menopausal hot flashes. Methods: Postmenopausal women (n = 38) reporting two or more hot flashes/day were randomly assigned to a low-fat, vegan diet, including ½ cup (86 g) of cooked soybeans daily, or to no diet changes for 12 weeks. Frequency and severity of hot flashes were recorded using a mobile application, and vasomotor, psychosocial, physical, and sexual symptoms were assessed using the Menopause-Specific Quality of Life Questionnaire. Significance was assessed using ...
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

The mediating effect of skeletal muscle index on the relationship between menarcheal age and bone mineral density in premenopausal women by race/ethnicity
Conclusions: SMI, as a full mediator, affected the relationship between menarcheal age and BMD among premenopausal women, and the mediating effects varied by race/ethnicity. To prevent or slow down the loss of hip/spine BMD and the development of osteoporosis, measures aiming at minimizing the risk for muscle mass loss should be recommended, especially for White and African-American women with late menarcheal age. (Source: Menopause)
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

Factors related to age at natural menopause in China: results from the China Kadoorie Biobank
Objectives: The aim of this study was to investigate the potentially modifiable factors affecting age at natural menopause (ANM) in Chinese women. Methods: We used cross-sectional data from the China Kadoorie Biobank study which that recruited 0.5 million (0.3 million women) Chinese adults aged 30 to 79 from 2004 to 2008. Multinomial logistic regression models were used to examine the relationships between ANM and various factors recorded at baseline. Results: Among 87,349 postmenopausal women, the mean ANM (SD) was 48.7 (4.3) years. Older age, being a housewife, earlier menarche, and passive smoking were...
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

Comparative venous thromboembolic safety of oral and transdermal postmenopausal hormone therapies among women Veterans
Conclusions: Among women veterans, the risk of VTE was similar in users of oral CEE, oral E2, and transdermal E2. These findings do not confirm the previously observed greater safety of transdermal and oral E2 over CEE. (Source: Menopause)
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

Dance practice modifies functional fitness, lipid profile, and self-image in postmenopausal women
Objective: The aim of the present study was to analyze the effects of dance practice on body composition, metabolic profile, functional fitness, and self-image/self-esteem in postmenopausal women. Methods: A total of 36 postmenopausal participants (mean age 57 years) danced three times per week for 90 minutes each day and were evaluated before and after 16 weeks. The parameters evaluated were body composition (body fat and lean mass), blood lipids, functional fitness, self-image, and self-esteem. Results: Statistical analysis was done using Student t test for paired samples and the Wilcoxon test with ...
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research

Hormone therapy formulation, dose, route of delivery, and risk of hypertension: findings from the Women's Health Initiative Observational Study (WHI-OS)
Objective: Using data from the Women's Health Initiative Observational Study (WHI-OS), to determine the role of estrogen formulation, dose, route of delivery, and its combination with different progestogens on the risk for hypertension in the WHI-OS. Methods: After excluding women with diagnosed hypertension, receiving antihypertensive medication, presenting with elevated blood pressure ( ≥ 140/90), and those not taking menopausal hormone therapy at baseline, 19,986 women remained eligible for the analyses. Using hierarchal modeling, proportional hazard rate calculation, and linear and logistic regression ...
Source: Menopause - October 1, 2021 Category: OBGYN Tags: Original Studies Source Type: research