Adiposity and insulin resistance as mediators between age at menarche and type 2 diabetes mellitus
Conclusions: Late menarche may be negatively associated with T2DM. The potential mechanism is adiposity and IR completely mediating the association between age at menarche and T2DM. (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Dietary inflammatory index and dietary energy density are associated with menopausal symptoms in postmenopausal women: a cross-sectional study
Conclusion: A proinflammatory diet was associated with higher menopause-specific somatic symptoms and higher DED was positively associated with menopausal symptoms. (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Differences between accelerometer cut point methods among midlife women with cardiovascular risk markers
Objective: Midlife women experience elevated risk for cardiovascular disease and often receive advice to increase physical activity to mitigate this risk. Use of accelerometers to measure ambulatory physical activity requires selection of appropriate thresholds for estimating moderate-to-vigorous physical activity (MVPA), and choice of cut points may lead to meaningfully different conclusions about midlife women's physical activity (PA) engagement. This is particularly important given the recent elimination of 10-minute bout requirements for MVPA. This two-phase study examined differences between four cut point methods a...
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Accelerated progression of waist-to-hip ratio but not body mass index associated with lower socioeconomic position: a cohort study of nonobese early postmenopausal Chinese women
Conclusions: Socioeconomic patterning was observed for the progression of WHR among nonobese Chinese women soon after menopause. Early postmenopausal stage may be a critical window for prevention of abdominal obesity among women with a lower educational attainment. (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Association between hysterectomy and depression: a longitudinal follow-up study using a national sample cohort
This study investigated the influence of hysterectomy on depression using a national sample cohort from South Korea. Methods: We extracted data entered into the Korean Health Insurance data based form 2002 through 2013 and classified patients into a group of women who had undergone a hysterectomy (n = 9,971) and a 1:4 matched control group (n = 39,884). A Cox proportional hazards model was used to analyze the hazard ratios (HRs) and 95% confidence intervals (CIs) to assess the risk of depression in the hysterectomy group and the control group. The HR was calculated as the risk of depression in the hysterectomy group...
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Changes in hot flash experiences and related factors in women with breast cancer
Objective: Taiwanese women are younger than women in western countries when diagnosed with breast cancer, and many of them are still menstruating. One of many distressing side effects reported by premenopausal women treated for breast cancer are hot flashes (HFs). The purposes of this study were to identify: (1) the trajectories of hot flash (HF) occurrence, frequency, and interference and (2) potential factors associated with HF changes. Methods: Peri- or premenopausal women newly diagnosed with breast cancer scheduled to receive chemotherapy and hormonal therapy were enrolled. HF frequency, HF interference, and othe...
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Efficacy and safety of ultra-low dose 0.005% estriol vaginal gel for the treatment of vulvovaginal atrophy in postmenopausal women with early breast cancer treated with nonsteroidal aromatase inhibitors: a phase II, randomized, double-blind, placebo-controlled trial
Conclusions: Ultra-low dose 0.005% estriol vaginal gel showed efficacy in improving the symptoms and signs of vulvovaginal atrophy. These results, together with minimal oscillations in hormonal levels throughout the treatment, support the use of ultra-low dose 0.005% estriol vaginal gel as a treatment option for vulvovaginal atrophy in women with breast cancer receiving NSAIs with an indication for treatment with vaginal estrogens. Video Summary:http://links.lww.com/MENO/A531. (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Interferential current: a new option for the treatment of sexual complaints in women with premature ovarian insufficiency using systemic hormone therapy: a randomized clinical trial
Objective: The aim of the study was to evaluate the efficacy of interferential current (IC) in the sexual function of women with premature ovarian insufficiency (POI) using systemic hormone therapy (HT), compared to topical estriol. Methods: A randomized clinical trial with 40 women with POI using systemic HT, who were sexually active and referred for dyspareunia and reduction of lubrication. The women were divided into two treatment groups for 4 weeks: IC group (eight electrotherapy sessions twice a week); or E group (estriol vaginal cream, daily application, 0.5 mg/d). The Female Sexual Function Index was used to ...
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Association of hot flushes with ghrelin and adipokines in early versus late postmenopausal women
Conclusions: Higher concentrations of ghrelin were associated with greater likelihood of hot flushes in both early- and late-postmenopausal women. Leptin, adiponectin, and resistin levels were not associated with hot flushes in postmenopausal women. (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

The association between hormone therapy and sarcopenia in postmenopausal women: the Korea National Health and Nutrition Examination Survey, 2008-2011
This study assessed the effect of HT on sarcopenia in postmenopausal women. Methods: The present study included 4,254 postmenopausal women who participated in the Korea National Health and Nutritional Examination Surveys from 2008 to 2011. Appendicular skeletal muscle mass divided by weight (ASM/Wt) and the prevalence of sarcopenia were analyzed in groups of women stratified by duration of HT use. Results: ASM/Wt was higher and the prevalence of sarcopenia was lower in participants with a history of prolonged (≥13 mo) HT use than in participants with a shorter duration of HT use or no HT use. After adjusting for m...
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Effects of NT-814, a dual neurokinin 1 and 3 receptor antagonist, on vasomotor symptoms in postmenopausal women: a placebo-controlled, randomized trial
Objectives: To evaluate the safety, pharmacokinetics, and preliminary efficacy of NT-814, a dual neurokinin 1,3 antagonist, in postmenopausal women with vasomotor symptoms (hot flashes). Methods: We completed a double-blind, randomized, placebo-controlled trial in three US clinical research units in 76 postmenopausal women with moderate/severe hot flashes. Participants were randomized to 14 days of once-daily NT-814 or placebo within each of four sequential dose cohorts; 50, 100, 150, and 300 mg. Participants completed diaries of hot flash frequency and severity and waking due to night sweats before (baseline) and d...
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Hormone therapy and sarcopenia: implications for the prevention of frailty as women age
No abstract available (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Editorials Source Type: research

The protagonist is a neurokinin 1, 3 antagonist
No abstract available (Source: Menopause)
Source: Menopause - May 1, 2020 Category: OBGYN Tags: Editorials Source Type: research

Gabapentin for the treatment of hot flushes in menopause: a meta-analysis
Objective: Gabapentin is used to treat vasomotor symptoms (VMS) in postmenopausal women with contraindications to hormonal therapy or who prefer alternatives. We investigated the efficacy and tolerability of gabapentin for treating menopausal hot flushes via a meta-analysis. Methods: We searched the PubMed, MEDLINE, EMBASE, and CENTRAL databases for English-language articles published until June, 2018. The following search terms were used: “menopause,” “hot flushes,” “vasomotor symptoms,” “gabapentin,” and “non-hormonal therapy.” Primary outcomes were frequen...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Review-Systematic Source Type: research

Lights on MsFLASH: a review of contributions
Conclusions: The MsFLASH trials contributed substantially to our understanding of bothersome menopausal symptom treatment. It is important that clinicians counseling women about available treatment options consider all therapies—both nonhormonal and hormonal. (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Clinical Corner: Invited Review Source Type: research

Association between common mental disorders, sleep quality, and menopausal symptoms: a population-based study in Southern Brazil
Objective: To investigate the association between common mental disorders (CMD), sleep quality, and moderate and severe menopausal symptoms in adult women in southern Brazil. Methods: This cross-sectional, population-based study investigated a representative sample of 393 women (age 40-69 years) living in an urban area. A standardized and pretested questionnaire that included the Self-Reporting Questionnaire-20 for CMD (Self-Reporting Questionnaire-20 ≥7), the Pittsburgh Sleep Quality Index-BR for sleep disorders (Pittsburgh Sleep Quality Index>5), and the Menopause Rating Scale for moderate/severe menopausal sy...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Relationship between BRSK1 rs12611091 variant and age at natural menopause based on physical activity
Objectives: The rs12611091 variant in the BR serine/threonine kinase 1 gene is one of the variants previously associated with age at natural menopause. So far, this variant has not been replicated in Taiwanese women. The purpose of this study was to determine the association between rs12611091 and age at natural menopause based on physical activity. Methods: A total of 1,758 women were eligible for analysis whose information about menopause was collected from the Taiwan Biobank. Multiple linear regression analysis was used for analysis. Results: The mean age (standard deviation) at natural menopause was 50.82 (3.59...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Pelvic floor disorders in women with premature ovarian insufficiency: a cross-sectional study
This study aimed to investigate the prevalence of self-reported main pelvic floor disorders (PFD) (urinary incontinence [UI], pelvic organ prolapse [POP], and fecal incontinence [FI]) and its associated factors in women with premature ovarian insufficiency (POI) and a control group. Methods: This was a cross-sectional study wherein two groups were interviewed from August, 2017 to November, 2018—women with POI (n = 150) and a control group matched for age and body weight (n = 150). Sociodemographic variables and two questionnaires validated in Brazilian Portuguese language for PFD (Kings Health Questionnair...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Quality over quantity: skeletal loading intensity plays a key role in understanding the relationship between physical activity and bone density in postmenopausal women
Conclusion: Despite having higher-than-expected PA, the low stepping loads observed in this cohort, along with half of the participants having low BMD measures, underscores the need for PA intensity to be considered in the management of postmenopausal bone health. (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Association of objectively measured sedentary behavior and physical activity levels with health-related quality of life in middle-aged women: The FLAMENCO project
Conclusions: Spending less time in sedentary behavior and greater physical activity levels, especially vigorous physical activity, are associated with better health-related quality of life in middle-aged women. Vigorous physical activity is associated with a better SF-36 physical component scale, which might mean a reduction in exercise time with similar improvements for women's quality of life. ClinicalTrials.gov Identifier: NCT02358109. Date of registration: 05/02/2015 (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Is it possible to investigate menopausal age? A comparative cross-sectional study of five cohorts between 1968 and 2017 from the Population Study of Women in Gothenburg, Sweden
Conclusions: This study has shown an increase in the hormonal use, in both 38- and 50-year-old women, making it difficult to determine when the actual menopause occurs. Thus, the previously found increasing secular trend in menopausal age will be more complicated to assess in female generations of today and tomorrow. (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

The European Vulvovaginal Epidemiological Survey (EVES): impact on sexual function of vulvovaginal atrophy of menopause
Objective: To estimate the impact of vulvovaginal atrophy (VVA) on sexual function in a clinical population of postmenopausal women. Methods: Women 45 to 75 years old and more than 12 months after the last menstruation, who attended menopausal/gynecological centers in Italy and Spain, were included. Women with at least one VVA symptom completed the following questionnaires: Day-to-Day Impact of Vaginal Aging (DIVA), Female Sexual Function Index (FSFI), and Female Sexual Distress Scale revised (FSDS-R). A physical gynecological examination was performed to confirm the VVA diagnosis. Data were analyzed by chi-square and...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Effect of rescue fractional microablative CO2 laser on symptoms and sexual dysfunction in women affected by vulvar lichen sclerosus resistant to long-term use of topic corticosteroid: a prospective longitudinal study
The objective of this study was to evaluate the efficacy of rescue fractional microablative CO2 laser treatment in women with severe symptoms and sexual dysfunction related to lichen sclerosus not responsive to long-term ultra-potent topical corticosteroid treatment. Methods: Consecutive eligible women with lichen sclerosus referred to our unit who received fractional microablative CO2 laser treatment after failure of ultra-potent topical corticosteroid treatment were enrolled in the study. The diagnosis was confirmed by histological assessment in all cases. Patients underwent two cycles of CO2 laser every 30 to 40 days...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Endometrial safety and bleeding profile of a 17β-estradiol/progesterone oral softgel capsule (TX-001HR)*
Objective: The aim of the study was to evaluate the effect of a single-capsule 17β-estradiol/progesterone (E2/P4), TX-001HR, on endometrial safety, to report on amenorrhea and bleeding patterns of users, and to identify predictors of amenorrhea. Methods: The REPLENISH trial (NCT01942668) evaluated use of TX-001HR in menopausal women (40-65 y) with vasomotor symptoms (VMS) and a uterus. Women were randomized to daily E2/P4 (mg/mg: 1/100, 0.5/100, 0.5/50, or 0.25/50), or placebo for 12 months. Incidence rate of endometrial hyperplasia was calculated from endometrial biopsies conducted at screening and study complet...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

The role of physical activity in the link between menopausal status and mental well-being
Objective: To examine the relationship between menopausal status and mental well-being, and whether this relationship varies as a function of physical activity (PA). Methods: Based on a hormonal analysis and bleeding diary, women aged 47 to 55 were categorized as pre (n = 304), early peri (n = 198), late peri (n = 209), or postmenopausal (n = 387). Mental well-being was assessed using the Centre for Epidemiologic Studies Depression Scale, the International Positive and Negative Affect Schedule Short Form, and the Satisfaction with Life Scale. PA was self-reported and categorized as low, medium, and hig...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Obstetrician-gynecologists’ screening and management of depression during perimenopause
Conclusion: Increased education of ob-gyn physicians related to depression during perimenopause may increase the screening and treatment of women during this phase of life. (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

A phase 2b, randomized, placebo-controlled, double-blind, dose-ranging study of the neurokinin 3 receptor antagonist fezolinetant for vasomotor symptoms associated with menopause
Objective: Menopausal vasomotor symptoms (VMS) may result from altered thermoregulatory control in brain regions innervated by neurokinin 3 receptor-expressing neurons. This phase 2b study evaluated seven dosing regimens of fezolinetant, a selective neurokinin 3 receptor antagonist, as a nonhormone approach for the treatment of VMS. Methods: Menopausal women aged>40-65 years with moderate/severe VMS (≥50 episodes/wk) were randomized (double-blind) to fezolinetant 15, 30, 60, 90 mg BID or 30, 60, 120 mg QD, or placebo for 12 weeks. Primary outcomes were reduction in moderate/severe VMS frequency and severit...
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Original Studies Source Type: research

The associations between menopausal symptoms and mental well-being: the role of types of physical activity
No abstract available (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Editorials Source Type: research

Towards improving recognition and management of perimenopausal depression
No abstract available (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Editorials Source Type: research

More promising news (mostly) on manipulating neurokinin B activity as a nonhormonal treatment of hot flashes
No abstract available (Source: Menopause)
Source: Menopause - March 31, 2020 Category: OBGYN Tags: Editorials Source Type: research

To the Editor
No abstract available (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Letter to the Editor Source Type: research

Taking a fresh look at mood, hormones, and menopause
Depression, with or without concomitant anxiety, is one of the most burdensome medical conditions worldwide. Depression affects women more often than men and may cause significant impairment. Reproductive phase-related windows of vulnerability for depression (new or recurrent) have been recognized, including the menopause transition. Midlife depression is likely influenced by both menopause- and nonmenopause-related factors. Antidepressants and cognitive behavioral therapy remain first-line treatment options for moderate to severe major depressive disorder at any time, with proven efficacy and tolerability in midlife women...
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Clinical Corner: NAMS Practice Pearl Source Type: research

Systemic estradiol levels with low-dose vaginal estrogens
Conclusion: Serum estradiol concentrations were generally lower when measured with more specific and sensitive assays. Estradiol absorption was dose-dependent, and may be influenced by dose, formulation, and positioning in the vagina. Very low systemic estradiol absorption with low/ultralow-dose vaginal estrogens may potentially decrease any adverse events that may be associated with higher doses of vaginal estrogens used for treating moderate to severe VVA due to less estradiol exposure. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Review Articles Source Type: research

Safety of vaginal estrogens: a systematic review
Conclusions: Newer low-dose estradiol rings, tablets, and inserts appear to induce the least increases in serum hormones, possibly indicating greater safety. Limited evidence in trials lasting up to 52 weeks suggest endometrial safety of vaginal estrogen use. Long-term trials are needed. Video Summary:http://links.lww.com/MENO/A513. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Review Articles Source Type: research

Design and psychometric analysis of a climacteric adjustment questionnaire for middle-aged women
Conclusion: The findings of the present study indicated that the validity and reliability of the questionnaire designed to measure the adjustment to the climacteric period in middle-aged women could be used in related studies. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

The effect of metformin on vertebral marrow fat in postmenopausal women with newly diagnosed type 2 diabetes mellitus
Objective: To determine the effect of metformin on marrow adiposity in postmenopausal women with newly diagnosed type 2 diabetes mellitus (T2DM). Methods: We enrolled 25 postmenopausal T2DM women who satisfied the requirement of having been on 1 year of metformin therapy and 26 age-matched healthy women receiving a placebo. All participants were analyzed for marrow fat fraction (FF) by magnetic resonance spectroscopy, vertebral volumetric bone mineral density (vBMD) by quantitative computed tomography, blood glucose, lipid profiles, and bone biomarkers to compare values before and after the interventions. Differences ...
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Plasma levels of miR-30d-5p are decreased in regularly exercising postmenopausal women
Objective: Plasma/serum microRNAs (miRNAs) are proposed to have a role in the development of osteoporosis, and their levels can be affected by physical activity. Therefore, the aim of this study was to analyze differences in plasma miRNAs levels in postmenopausal women and to simultaneously find novel extracellular miRNAs that are associated with variations in physical activities. Methods: We measured hsa-miR-148a-3p, hsa-miR-125b, hsa-miR-21-5p, hsa-miR-93-5p, and hsa-miR-30d-5p in a cohort of 149 postmenopausal women divided into subgroups based on the amount of physical activity by using quantitative polymerase cha...
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Menopause and risk of hip fracture in middle-aged Chinese women: a 10-year follow-up of China Kadoorie Biobank
Objective: Bone loss is accelerated after menopause in women, as is the risk of hip fracture, but little is known about the importance of age at menopause, time since menopause, and total reproductive years for risk of hip fracture. Methods: Between 2004 and 2008, the China Kadoorie Biobank recruited 125,336 postmenopausal women who had a natural menopause and recorded 1,327 incident cases of hip fracture during the first 10 years of follow-up. Multivariable Cox regression was used to estimate hazard ratios and 95% CIs for incident hip fracture for age at menopause, time since menopause, and total reproductive years. ...
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Menopausal hormone therapy, blood thrombogenicity, and development of white matter hyperintensities in women of the Kronos Early Estrogen Prevention Study
Conclusion: In recently menopausal women, the type of MHT did not significantly influence the association of markers of blood thrombogenicity with development of WMH in the brain. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Effects of menopause on sleep quality and sleep disorders: Canadian Longitudinal Study on Aging
Conclusions: Menopause is associated with increased sleep-onset insomnia. Postmenopausal women also are more likely to screen positive for OSA. However, menopausal status is not associated with sleep maintenance, somnolence, or RLS, and RBD. Video Summary:http://links.lww.com/MENO/A501. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

“I want to feel like I used to feel”: a qualitative study of causes of low libido in postmenopausal women
Conclusions: A wide variety of factors contribute to low libido in women over 60, but many of these factors are addressable. Low libido in older women should not be automatically attributed to “normal” aging or to menopause; providers should take an approach to assessment and treatment that addresses biological, interpersonal and social, and psychological factors. Video Summary: http://links.lww.com/MENO/A499 (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Trajectory analysis of sleep maintenance problems in midlife women before and after surgical menopause: the Study of Women's Health Across the Nation (SWAN)
Objective: Investigate temporal patterns of sleep maintenance problems in women who became surgically menopausal (hysterectomy with bilateral oophorectomy) before their final menstrual period and examine whether presurgery trajectories of sleep maintenance problems are related to problems staying asleep postsurgery. Methods: Longitudinal analysis of sleep self-reports collected every 1 to 2 years from 1996 to 2013 from 176 surgically menopausal women in the Study of Women's Health Across the Nation, a seven-site community-based, multiethnic/multiracial, cohort study. Median follow-up was 15.3 years (4.2 years presurge...
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Hot flashes are associated with altered brain function during a memory task
Objective: Vasomotor symptoms (VMS) are associated with decreased memory performance and alterations in brain function. We conducted a preliminary examination of VMS and patterns of brain activity during a verbal memory task to provide insights into the VMS-related brain mechanisms that can contribute to memory problems in midlife women. Methods: Fourteen postmenopausal women (mean age 53.5, 64% African-American) with moderate-to-severe VMS (>35/wk) and not taking hormone therapy completed functional magnetic resonance imaging (fMRI) assessments during word encoding and recognition, 24-hour physiologic VMS monitori...
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Interaction between postmenopausal hormone therapy and diabetes on cataract
Conclusions: Long-term HT use and type 2 diabetes interact in their relationship with cataract. This novel finding should be confirmed. If confirmed, women with type 2 diabetes should be informed that long-term HT use increases their risk of cataract. Video Summary:http://links.lww.com/MENO/A519. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Heart fat and carotid artery atherosclerosis progression in recently menopausal women: impact of menopausal hormone therapy: The KEEPS trial
Conclusion: Compared with t-E2, o-CEE appears to slow down the adverse effect of increasing PAT on progression of atherosclerosis. Whether this beneficial association is specific to CEE or to the oral route of CEE administration is unclear and should be assessed further. (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Clear vision in postmenopausal women: role of hormone therapy and diabetes
No abstract available (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Editorials Source Type: research

Vet for fat—epicardial versus paracardial types and atherosclerosis risk
No abstract available (Source: Menopause)
Source: Menopause - February 29, 2020 Category: OBGYN Tags: Editorials Source Type: research

In Reply
No abstract available (Source: Menopause)
Source: Menopause - January 31, 2020 Category: OBGYN Tags: Letters to the Editor Source Type: research

To the Editor
No abstract available (Source: Menopause)
Source: Menopause - January 31, 2020 Category: OBGYN Tags: Letters to the Editor Source Type: research

Hormonal management of menopausal symptoms in women with a history of gynecologic malignancy
Conclusions: The risks of hormone therapy should be assessed on an individual basis, with consideration of age, type of hormone therapy, dose, duration of use, regimen, route, and prior exposure. Systemic hormone therapy is not recommended in breast cancer survivors, whereas vaginal low-dose estrogen appears safe. Hormone therapy may be used by endometrial, cervical, and ovarian cancer survivors with low-risk, non-estrogen-receptor–positive subtypes. Video Summary:http://links.lww.com/MENO/A516. (Source: Menopause)
Source: Menopause - January 31, 2020 Category: OBGYN Tags: Review Article Source Type: research