Transdermal estrogen therapy in menopausal women at increased risk for thrombotic events: a scoping review
Conclusion:
In women with prior VTE, two studies found a decrease in coagulability and no increased risk of recurrent VTE with transdermal MHT use. In women with increased body mass index, three studies found no increased VTE risk in transdermal MHT users. In women with prothrombotic genetic polymorphisms, three studies found minimal to no increased VTE risk in transdermal MHT users. In women with various proinflammatory comorbidities, five studies found an improved thrombotic profile and no increased VTE risk with transdermal MHT use. This scoping review provides data regarding the safety of transdermal MHT use in pos...
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Review-Narrative Source Type: research
Safety and efficacy of compounded bioidentical hormone therapy (cBHT) in perimenopausal and postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
Conclusions and Relevance:
This review found that cBHT used in primarily short-term RCTs is not associated with adverse changes in lipid profile or glucose metabolism. cBHT in the form of vaginal androgens appears beneficial for vaginal atrophy symptoms. There are insufficient RCTs of cBHT to assess clinical risk of breast cancer, endometrial cancer, or cardiovascular disease. Long-term studies with clinical endpoints are needed. (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Review-Systematic Source Type: research
Effects of menopause on the retinal nerve fiber layer and ganglion cell complex and on intraocular pressure
Objective:
To compare the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness and intraocular pressure in reproductive age and postmenopausal women.
Methods:
The study included 94 eyes of 47 reproductive age women (Group 1) and 94 eyes of 47 postmenopausal women (Group 2). In all women, RNFL and GCC thicknesses were measured by optical coherence tomography. Intraocular pressure levels were measured by Goldmann applanation tonometry. Generalized linear mixed models were conducted to test the differences between groups. Age- and body mass index (BMI)-adjusted partial correlation analysis was...
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Association of adiposity evaluated by anthropometric, BIA, and DXA measures with cardiometabolic risk factors in nonobese postmenopausal women: the CoLaus/OsteoLaus cohort
Conclusions:
BIA seems not to be a good tool to assess VAT. At the population level, waist circumference and body mass index seem to be good tools to estimate VAT. VAT measured by DXA is the parameter most correlated with cardiometabolic risk factors and could become a component of the cardiometabolic marker on its own. (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Psychological well-being of midlife women: a structural equation modeling approach
Conclusions:
To improve the psychological well-being of middle-aged women, it is important to increase their self-efficacy and minimize stress. Moreover, managing menopausal symptoms and increasing self-compassion through effective coping may maximize psychological well-being.
Video Summary:
http://links.lww.com/MENO/A933. (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Resilience and psychosocial factors linked to symptom experience during the menopause transition for women living with HIV*
Objective:
Women living with HIV (WLWH) are commonly symptomatic during perimenopause and menopause (≥1 y without menstruation), however, little is known of risks for symptoms and their timing. We analyzed these unwanted experiences to inform care.
Methods:
WLWH (≥40 y) in the Canadian HIV Women’s Sexual and Reproductive Health Cohort Study rated midlife experiences for seven symptoms and a symptom composite (from 0 to 21). Timing was categorized into four phases: i) perimenopause (flow in the last year), ii) 1-2 years from final menstrual period (FMP), iii) 2-5 years post-FMP; and iv)>5 years post-FMP. Re...
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Patterns of mental health symptoms among women living with HIV ages 45-60 in England: associations with demographic and clinical factors
Objective:
We aimed to describe the prevalence of various mental health symptoms according to menopausal status (pre, peri, post) among women living with HIV ages 45-60 in England, and to identify groups of women with similar general and menopause-related mental health symptoms. We then investigated demographic predictors of group-membership and group differences in HIV-related care outcomes (antiretroviral therapy adherence, HIV clinic attendance, CD4-count, and last HIV viral load).
Methods:
An analysis of cross-sectional data from the Positive Transitions through Menopause study, an observational study of the...
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Prevalence of female pattern hair loss in postmenopausal women: a cross-sectional study
Conclusion: The prevalence of FPHL was high in postmenopausal women, raising the need for hair loss awareness in menopause clinics. Early detection and proper treatment of FPHL may increase the quality of life in postmenopausal women. (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Resilience and sexual health among menopausal women: a cross-sectional study
In this study, we assessed resilience, sexual function, and quality of life among a sample of mid-aged Spanish menopausal women.
Methods:
This cross-sectional study was performed in 101 symptomatic menopausal women. Participants filled out the 14-item Wagnild and Young Resilience Scale, the 19-item Female Sexual Function Index (FSFI), the 16-item Cervantes-SF form, and a sociodemographic questionnaire.
Results:
Resilience scores were significantly higher among women with high sexual function scores (FSFI> 26), with a 14-item Wagnild and Young Resilience Scale total valuation of 86 [80-94] versus 74 [66-79.50]...
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Toward a better measure of midlife sexual function: pooled analyses in nearly 1,000 women participating in MsFLASH randomized trials
Objective:
Evaluate appropriateness of the current Female Sexual Function Index (FSFI)-19 value of (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Translabial ultrasound indices of failed pessary fittings in women with symptomatic pelvic organ prolapse
Conclusions:
Younger age, LAM avulsion, enterocele, and sizeable HA on Valsalva proved independently predictive of failed pessary fittings in women with symptomatic POP. (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Metabolic effects of menopause: a cross-sectional characterization of body composition and exercise metabolism
Conclusions:
Perimenopause may be the most opportune window for lifestyle intervention, as this group experienced the onset of unfavorable body composition and metabolic characteristics.
Video Summary:
http://links.lww.com/MENO/A932. (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Original Study Source Type: research
Pessaries: valuable interventions for symptomatic pelvic organ prolapse
No abstract available (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Editorial Source Type: research
Can 50 ever be the new 40, metabolically speaking?
No abstract available (Source: Menopause)
Source: Menopause - April 1, 2022 Category: OBGYN Tags: Editorial Source Type: research
Menopausal experiences of South Asian immigrant women: a scoping review
Conclusion:
Findings of this scoping review can help guide the development and evaluation of menopause interventions for South Asian immigrant women. Culturally sensitive care, increased discussion on sexual health, support networks, and reduction of socioeconomic barriers are needed to address the health needs of South Asian immigrant women. Further research is needed to better understand South Asian immigrant women's menopausal needs and help guide intervention design. (Source: Menopause)
Source: Menopause - February 27, 2022 Category: OBGYN Tags: Review Articles Source Type: research
