High-throughput quantification of microbial-derived organic acids in mucin-rich samples via reverse phase high performance liquid chromatography
J Med Microbiol. 2023 Jun;72(6). doi: 10.1099/jmm.0.001708.ABSTRACTOrganic acids (short chain fatty acids, amino acids, etc.) are common metabolic byproducts of commensal bacteria of the gut and oral cavity in addition to microbiota associated with chronic infections of the airways, skin, and soft tissues. A ubiquitous characteristic of these body sites in which mucus-rich secretions often accumulate in excess, is the presence of mucins; high molecular weight (HMW), glycosylated proteins that decorate the surfaces of non-keratinized epithelia. Owing to their size, mucins complicate quantification of microbial-derived metab...
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Alex R Villarreal Sarah K Lucas Joshua R Fletcher Ryan C Hunter Source Type: research
Class 1 integrons in clinical and swine industry isolates of < em > Salmonella < /em > Typhimurium from Colombia, dating 1997 to 2017
Conclusions. The widespread presence of the IntI1-Col1 integron in Colombia since 1997 was striking. A possible relationship between integrons, source and mobile elements that favour the spread of antimicrobial resistance determinants in Colombian S. Typhimurium was identified.PMID:37294286 | DOI:10.1099/jmm.0.001704 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Nancy Yaneth Fl órez-Delgado Elizabeth Noelia Ubillus Blanca Perez-Sepulveda Eyda Lizeth Ospina-R íos Ana Karina Carrascal-Camacho Iliana C Chamorro-Tobar Lucy Angeline Monta ño Yan Li Silvana Zapata-Bedoya Jay C D Hinton Jos é Miguel Villarreal Magda Source Type: research
Characterization of a < em > Helicobacter pylori < /em > strain with high biofilm-forming ability
Conclusion. There is substantial variation in biofilm-forming ability in H. pylori, but this was not significantly associated with disease severity in our study. We identified and characterized an interesting strain with high biofilm-forming ability, including generation and analysis of the complete genome.PMID:37294289 | DOI:10.1099/jmm.0.001710 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Daniel Wilkinson Lolwah Alsharaf Stephen Thompson Andreja Paulin Rhodrick Takor Abed Zaitoun Karen Robinson Jonathan Thomas Gareth McVicker Jody Winter Source Type: research
MARGINAL NOTES, April 2023. Learning to breathe again
J Med Microbiol. 2023 Jun;72(4). doi: 10.1099/jmm.0.001709.NO ABSTRACTPMID:37294292 | DOI:10.1099/jmm.0.001709 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Timothy J J Inglis Source Type: research
CLEC4A and CLEC12B C-type lectin receptors mediate interactions with < em > Pneumocystis < /em > cell wall components
Conclusion. The data presented here provide new members of the CLRs family recognizing Pneumocystis. Future studies using CLEC4A and/or CLEC12B deficient mice in the PCP mouse model should provide further insights into the host immunological response to Pneumocystis.PMID:37294293 | DOI:10.1099/jmm.0.001714 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Theodore J Kottom Eva M Carmona Kyle Schaefbauer Andrew H Limper Source Type: research
Temporal shifts in the predominant carbapenemase gene types among carbapenemase-producing < em > Klebsiella pneumoniae < /em > isolated in Bangkok, Thailand, during 2013-2016
Conclusion. Our findings suggest that a substantial change in CPE types occurred in Thailand and potentially in Southeast Asian countries.PMID:37294294 | DOI:10.1099/jmm.0.001711 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Noriko Sakamoto Warawut Laolerd Yukihiro Akeda Yo Sugawara Daisuke Motooka Norihisa Yamamoto Dan Takeuchi Rathina Kumar Shanmugakani Isao Nishi Masato Suzuki Keigo Shibayama Tetsuya Iida Pitak Santanirand Kazunori Tomono Shigeyuki Hamada Source Type: research
< em > Escherichia coli < /em > encoding Shiga toxin subtype Stx2f causing human infections in England, 2015-2022
Conclusions. Certain serotypes of E. coli harbouring stx2f cause severe clinical outcomes, including STEC-HUS. Public health advice and possible interventions are limited, as little is known about the animal and environmental reservoirs and transmission routes. We recommend more comprehensive and standardized collection of microbiological and epidemiological data, and routine sharing of sequencing data between public health agencies worldwide.PMID:37294302 | DOI:10.1099/jmm.0.001707 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Anouschka Den Ouden David R Greig Ella V Rodwell Francesco Tripodo Israel Olonade Craig Swift Claire Jenkins Source Type: research
Gut bacteria and sex differences in colorectal cancer
Conclusion. Gut bacteria were correlated with sexes and CRC. It is necessary to consider gender when gut bacteria are used to treat and predict CRC.PMID:37294282 | DOI:10.1099/jmm.0.001706 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Xi Yang Ping Li Zhanbo Qu Jing Zhuang Yinhang Wu Wei Wu Qichun Wei Source Type: research
High-throughput quantification of microbial-derived organic acids in mucin-rich samples via reverse phase high performance liquid chromatography
J Med Microbiol. 2023 Jun;72(6). doi: 10.1099/jmm.0.001708.ABSTRACTOrganic acids (short chain fatty acids, amino acids, etc.) are common metabolic byproducts of commensal bacteria of the gut and oral cavity in addition to microbiota associated with chronic infections of the airways, skin, and soft tissues. A ubiquitous characteristic of these body sites in which mucus-rich secretions often accumulate in excess, is the presence of mucins; high molecular weight (HMW), glycosylated proteins that decorate the surfaces of non-keratinized epithelia. Owing to their size, mucins complicate quantification of microbial-derived metab...
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Alex R Villarreal Sarah K Lucas Joshua R Fletcher Ryan C Hunter Source Type: research
Class 1 integrons in clinical and swine industry isolates of < em > Salmonella < /em > Typhimurium from Colombia, dating 1997 to 2017
Conclusions. The widespread presence of the IntI1-Col1 integron in Colombia since 1997 was striking. A possible relationship between integrons, source and mobile elements that favour the spread of antimicrobial resistance determinants in Colombian S. Typhimurium was identified.PMID:37294286 | DOI:10.1099/jmm.0.001704 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Nancy Yaneth Fl órez-Delgado Elizabeth Noelia Ubillus Blanca Perez-Sepulveda Eyda Lizeth Ospina-R íos Ana Karina Carrascal-Camacho Iliana C Chamorro-Tobar Lucy Angeline Monta ño Yan Li Silvana Zapata-Bedoya Jay C D Hinton Jos é Miguel Villarreal Magda Source Type: research
Characterization of a < em > Helicobacter pylori < /em > strain with high biofilm-forming ability
Conclusion. There is substantial variation in biofilm-forming ability in H. pylori, but this was not significantly associated with disease severity in our study. We identified and characterized an interesting strain with high biofilm-forming ability, including generation and analysis of the complete genome.PMID:37294289 | DOI:10.1099/jmm.0.001710 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Daniel Wilkinson Lolwah Alsharaf Stephen Thompson Andreja Paulin Rhodrick Takor Abed Zaitoun Karen Robinson Jonathan Thomas Gareth McVicker Jody Winter Source Type: research
MARGINAL NOTES, April 2023. Learning to breathe again
J Med Microbiol. 2023 Jun;72(4). doi: 10.1099/jmm.0.001709.NO ABSTRACTPMID:37294292 | DOI:10.1099/jmm.0.001709 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Timothy J J Inglis Source Type: research
CLEC4A and CLEC12B C-type lectin receptors mediate interactions with < em > Pneumocystis < /em > cell wall components
Conclusion. The data presented here provide new members of the CLRs family recognizing Pneumocystis. Future studies using CLEC4A and/or CLEC12B deficient mice in the PCP mouse model should provide further insights into the host immunological response to Pneumocystis.PMID:37294293 | DOI:10.1099/jmm.0.001714 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Theodore J Kottom Eva M Carmona Kyle Schaefbauer Andrew H Limper Source Type: research
Temporal shifts in the predominant carbapenemase gene types among carbapenemase-producing < em > Klebsiella pneumoniae < /em > isolated in Bangkok, Thailand, during 2013-2016
Conclusion. Our findings suggest that a substantial change in CPE types occurred in Thailand and potentially in Southeast Asian countries.PMID:37294294 | DOI:10.1099/jmm.0.001711 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Noriko Sakamoto Warawut Laolerd Yukihiro Akeda Yo Sugawara Daisuke Motooka Norihisa Yamamoto Dan Takeuchi Rathina Kumar Shanmugakani Isao Nishi Masato Suzuki Keigo Shibayama Tetsuya Iida Pitak Santanirand Kazunori Tomono Shigeyuki Hamada Source Type: research
< em > Escherichia coli < /em > encoding Shiga toxin subtype Stx2f causing human infections in England, 2015-2022
Conclusions. Certain serotypes of E. coli harbouring stx2f cause severe clinical outcomes, including STEC-HUS. Public health advice and possible interventions are limited, as little is known about the animal and environmental reservoirs and transmission routes. We recommend more comprehensive and standardized collection of microbiological and epidemiological data, and routine sharing of sequencing data between public health agencies worldwide.PMID:37294302 | DOI:10.1099/jmm.0.001707 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Anouschka Den Ouden David R Greig Ella V Rodwell Francesco Tripodo Israel Olonade Craig Swift Claire Jenkins Source Type: research