CXCR2 perturbation promotes < em > Staphylococcus aureus < /em > implant-associated infection
Conclusion. Our results demonstrate that CXCR2 plays an essential role in regulating the severity of S. aureus implant-associated infections. Interestingly, however, perturbation of CXCR2 expression or signalling both resulted in enhanced Cxcr2 transcription and elevated implant-associated bacterial burdens. Thus, CXCR2 appears finely tuned to efficiently recruit effector cells and mediate control of S. aureus biofilm-mediated infection.PMID:38567642 | DOI:10.1099/jmm.0.001821 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 3, 2024 Category: Microbiology Authors: Mike Akaraphanth Tara M Nordgren Casey M Gries Source Type: research
Characterization of invasive Group B < em > Streptococcus < /em > isolates from Western Australian infants, 2004-2020
Conclusions. Based on comprehensive characterization of invasive infant GBS in Western Australia, we found that coverage for leading capsular polysaccharide and surface protein vaccine candidates was high. The demonstrated changes in serotype and molecular type highlight the need for ongoing surveillance, particularly with regard to future GBS vaccination programmes. The reduced susceptibility to IAP agents over time should inform changes to antibiotic guidelines.PMID:38567639 | DOI:10.1099/jmm.0.001822 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 3, 2024 Category: Microbiology Authors: Ginger Hilpipre Lucy L Furfaro Michelle Porter Christopher C Blyth Daniel K Yeoh Source Type: research
CXCR2 perturbation promotes < em > Staphylococcus aureus < /em > implant-associated infection
Conclusion. Our results demonstrate that CXCR2 plays an essential role in regulating the severity of S. aureus implant-associated infections. Interestingly, however, perturbation of CXCR2 expression or signalling both resulted in enhanced Cxcr2 transcription and elevated implant-associated bacterial burdens. Thus, CXCR2 appears finely tuned to efficiently recruit effector cells and mediate control of S. aureus biofilm-mediated infection.PMID:38567642 | DOI:10.1099/jmm.0.001821 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 3, 2024 Category: Microbiology Authors: Mike Akaraphanth Tara M Nordgren Casey M Gries Source Type: research
Characterization of invasive Group B < em > Streptococcus < /em > isolates from Western Australian infants, 2004-2020
Conclusions. Based on comprehensive characterization of invasive infant GBS in Western Australia, we found that coverage for leading capsular polysaccharide and surface protein vaccine candidates was high. The demonstrated changes in serotype and molecular type highlight the need for ongoing surveillance, particularly with regard to future GBS vaccination programmes. The reduced susceptibility to IAP agents over time should inform changes to antibiotic guidelines.PMID:38567639 | DOI:10.1099/jmm.0.001822 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 3, 2024 Category: Microbiology Authors: Ginger Hilpipre Lucy L Furfaro Michelle Porter Christopher C Blyth Daniel K Yeoh Source Type: research
CXCR2 perturbation promotes < em > Staphylococcus aureus < /em > implant-associated infection
Conclusion. Our results demonstrate that CXCR2 plays an essential role in regulating the severity of S. aureus implant-associated infections. Interestingly, however, perturbation of CXCR2 expression or signalling both resulted in enhanced Cxcr2 transcription and elevated implant-associated bacterial burdens. Thus, CXCR2 appears finely tuned to efficiently recruit effector cells and mediate control of S. aureus biofilm-mediated infection.PMID:38567642 | DOI:10.1099/jmm.0.001821 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 3, 2024 Category: Microbiology Authors: Mike Akaraphanth Tara M Nordgren Casey M Gries Source Type: research
Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research
Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research
Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research
Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research
Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research
Cancer invasion and anaerobic bacteria: new insights into mechanisms
J Med Microbiol. 2024 Mar;73(3). doi: 10.1099/jmm.0.001817.ABSTRACTThere is growing evidence that altered microbiota abundance of a range of specific anaerobic bacteria are associated with cancer, including Peptoniphilus spp., Porphyromonas spp., Fusobacterium spp., Fenollaria spp., Prevotella spp., Sneathia spp., Veillonella spp. and Anaerococcus spp. linked to multiple cancer types. In this review we explore these pathogenic associations. The mechanisms by which bacteria are known or predicted to interact with human cells are reviewed and we present an overview of the interlinked mechanisms and hypotheses of how multiple...
Source: Journal of Medical Microbiology - March 27, 2024 Category: Microbiology Authors: Rachel Hurst Daniel S Brewer Abraham Gihawi John Wain Colin S Cooper Source Type: research
Anthraquinones against < em > Cryptococcus neoformans sensu stricto < /em > : antifungal interaction, biofilm inhibition and pathogenicity in the < em > Caenorhabditis elegans < /em > model
Conclusion. These results highlight the potential activity of anthraquinones to increase the effectiveness of antifungal drugs against cryptococcal biofilms.PMID:38530134 | DOI:10.1099/jmm.0.001815 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 26, 2024 Category: Microbiology Authors: G éssica Dos Santos Araújo Raimunda S âmia Nogueira Brilhante Maria Gleiciane da Rocha Lara de Aguiar D ébora de Souza Collares Maia Castelo-Branco Glaucia Morgana de Melo Guedes Jos é Júlio Costa Sidrim Waldemiro Aquino Pereira Neto Marcos F ábio Source Type: research
Anthraquinones against < em > Cryptococcus neoformans sensu stricto < /em > : antifungal interaction, biofilm inhibition and pathogenicity in the < em > Caenorhabditis elegans < /em > model
Conclusion. These results highlight the potential activity of anthraquinones to increase the effectiveness of antifungal drugs against cryptococcal biofilms.PMID:38530134 | DOI:10.1099/jmm.0.001815 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 26, 2024 Category: Microbiology Authors: G éssica Dos Santos Araújo Raimunda S âmia Nogueira Brilhante Maria Gleiciane da Rocha Lara de Aguiar D ébora de Souza Collares Maia Castelo-Branco Glaucia Morgana de Melo Guedes Jos é Júlio Costa Sidrim Waldemiro Aquino Pereira Neto Marcos F ábio Source Type: research
< em > Clostridioides difficile < /em > detection and infection in children: are they just small adults?
J Med Microbiol. 2024 Mar;73(3). doi: 10.1099/jmm.0.001816.ABSTRACTClostridioides difficile is a well-recognized healthcare-associated pathogen, with its significance widely recognized in adult populations. Despite this, there is limited data on the significance of detection within paediatric populations, both for individual patient management and wider transmission risk-based considerations. High rates of colonization are understood to occur in infants, with increasing levels up to 11 months, and colonization rates similar to adults by 8 years old. Sources of C. difficile are ubiquitous, with detection in companion animal...
Source: Journal of Medical Microbiology - March 25, 2024 Category: Microbiology Authors: Sam Watkin Francis Yongblah James Burton John C Hartley Elaine Cloutman-Green Source Type: research
< em > Clostridioides difficile < /em > detection and infection in children: are they just small adults?
J Med Microbiol. 2024 Mar;73(3). doi: 10.1099/jmm.0.001816.ABSTRACTClostridioides difficile is a well-recognized healthcare-associated pathogen, with its significance widely recognized in adult populations. Despite this, there is limited data on the significance of detection within paediatric populations, both for individual patient management and wider transmission risk-based considerations. High rates of colonization are understood to occur in infants, with increasing levels up to 11 months, and colonization rates similar to adults by 8 years old. Sources of C. difficile are ubiquitous, with detection in companion animal...
Source: Journal of Medical Microbiology - March 25, 2024 Category: Microbiology Authors: Sam Watkin Francis Yongblah James Burton John C Hartley Elaine Cloutman-Green Source Type: research
