Urinary tract infections: a review of the current diagnostics landscape
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001780.ABSTRACTUrinary tract infections are the most common bacterial infections worldwide. Infections can range from mild, recurrent (rUTI) to complicated (cUTIs), and are predominantly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy is important to tackle infection; however, with the continued emergence of antibiotic resistance there is an urgent need to monitor the use of effective antibiotics through better stewardship measures. Currently, clinical diagnosis of UTIs relies on empiric methods supported by laboratory testing including cellular analy...
Source: Journal of Medical Microbiology - November 15, 2023 Category: Microbiology Authors: Braith Grey Mathew Upton Lovleen Tina Joshi Source Type: research

Urinary tract infections: a review of the current diagnostics landscape
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001780.ABSTRACTUrinary tract infections are the most common bacterial infections worldwide. Infections can range from mild, recurrent (rUTI) to complicated (cUTIs), and are predominantly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy is important to tackle infection; however, with the continued emergence of antibiotic resistance there is an urgent need to monitor the use of effective antibiotics through better stewardship measures. Currently, clinical diagnosis of UTIs relies on empiric methods supported by laboratory testing including cellular analy...
Source: Journal of Medical Microbiology - November 15, 2023 Category: Microbiology Authors: Braith Grey Mathew Upton Lovleen Tina Joshi Source Type: research

Urinary tract infections: a review of the current diagnostics landscape
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001780.ABSTRACTUrinary tract infections are the most common bacterial infections worldwide. Infections can range from mild, recurrent (rUTI) to complicated (cUTIs), and are predominantly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy is important to tackle infection; however, with the continued emergence of antibiotic resistance there is an urgent need to monitor the use of effective antibiotics through better stewardship measures. Currently, clinical diagnosis of UTIs relies on empiric methods supported by laboratory testing including cellular analy...
Source: Journal of Medical Microbiology - November 15, 2023 Category: Microbiology Authors: Braith Grey Mathew Upton Lovleen Tina Joshi Source Type: research

Urinary tract infections: a review of the current diagnostics landscape
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001780.ABSTRACTUrinary tract infections are the most common bacterial infections worldwide. Infections can range from mild, recurrent (rUTI) to complicated (cUTIs), and are predominantly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy is important to tackle infection; however, with the continued emergence of antibiotic resistance there is an urgent need to monitor the use of effective antibiotics through better stewardship measures. Currently, clinical diagnosis of UTIs relies on empiric methods supported by laboratory testing including cellular analy...
Source: Journal of Medical Microbiology - November 15, 2023 Category: Microbiology Authors: Braith Grey Mathew Upton Lovleen Tina Joshi Source Type: research

Urinary tract infections: a review of the current diagnostics landscape
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001780.ABSTRACTUrinary tract infections are the most common bacterial infections worldwide. Infections can range from mild, recurrent (rUTI) to complicated (cUTIs), and are predominantly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy is important to tackle infection; however, with the continued emergence of antibiotic resistance there is an urgent need to monitor the use of effective antibiotics through better stewardship measures. Currently, clinical diagnosis of UTIs relies on empiric methods supported by laboratory testing including cellular analy...
Source: Journal of Medical Microbiology - November 15, 2023 Category: Microbiology Authors: Braith Grey Mathew Upton Lovleen Tina Joshi Source Type: research

Urinary tract infections: a review of the current diagnostics landscape
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001780.ABSTRACTUrinary tract infections are the most common bacterial infections worldwide. Infections can range from mild, recurrent (rUTI) to complicated (cUTIs), and are predominantly caused by uropathogenic Escherichia coli (UPEC). Antibiotic therapy is important to tackle infection; however, with the continued emergence of antibiotic resistance there is an urgent need to monitor the use of effective antibiotics through better stewardship measures. Currently, clinical diagnosis of UTIs relies on empiric methods supported by laboratory testing including cellular analy...
Source: Journal of Medical Microbiology - November 15, 2023 Category: Microbiology Authors: Braith Grey Mathew Upton Lovleen Tina Joshi Source Type: research

< em > Mycobacterium bovis < /em > and its impact on human and animal tuberculosis
J Med Microbiol. 2023 Nov;72(11). doi: 10.1099/jmm.0.001769.NO ABSTRACTPMID:37962183 | DOI:10.1099/jmm.0.001769 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 14, 2023 Category: Microbiology Authors: Jason Sawyer Shelley Rhodes Gareth J Jones Philip J Hogarth H Martin Vordermeier Source Type: research

High incidence of antibiotic resistance amongst isolates of < em > Helicobacter pylori < /em > collected in Nottingham, UK, between 2001 and 2018
Conclusion. Although there was high and increasing resistance to clarithromycin and metronidazole, there was no resistance to tetracycline and the frequencies of amoxicillin and levofloxacin resistance were very low.PMID:37962209 | DOI:10.1099/jmm.0.001776 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 14, 2023 Category: Microbiology Authors: Elizabeth Garvey Joanne Rhead Suffi Suffian Daniel Whiley Farah Mahmood Naveen Bakshi Darren Letley Jonathan White John Atherton Jody Anne Winter Karen Robinson Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research

Excretory-secretory products from adult helminth < em > Nippostrongylus brasiliensis < /em > have < em > in vitro < /em > bactericidal activity
Conclusion. The results of this study demonstrate that helminths such as Nippostrongylus brasiliensis release molecules via their excretory-secretory pathway that have broad-spectrum bactericidal activity. The mechanisms responsible for this bactericidal activity remain to be determined and further studies aimed at isolating and identifying active bactericidal molecules are needed.PMID:37929930 | DOI:10.1099/jmm.0.001762 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - November 6, 2023 Category: Microbiology Authors: Roxanne Pillay Zilungile L Mkhize-Kwitshana William G C Horsnell Christopher Icke Ian Henderson Murray E Selkirk Rita Berkachy Pragalathan Naidoo Abraham J Niehaus Ravesh Singh Adam F Cunningham Matthew K O'Shea Source Type: research