< em > Escherichia coli < /em > encoding Shiga toxin subtype Stx2f causing human infections in England, 2015-2022
Conclusions. Certain serotypes of E. coli harbouring stx2f cause severe clinical outcomes, including STEC-HUS. Public health advice and possible interventions are limited, as little is known about the animal and environmental reservoirs and transmission routes. We recommend more comprehensive and standardized collection of microbiological and epidemiological data, and routine sharing of sequencing data between public health agencies worldwide.PMID:37294302 | DOI:10.1099/jmm.0.001707 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Anouschka Den Ouden David R Greig Ella V Rodwell Francesco Tripodo Israel Olonade Craig Swift Claire Jenkins Source Type: research
Using gut microbiota as a diagnostic tool for colorectal cancer: machine learning techniques reveal promising results
Conclusions. Our results suggested an association between gut microbiota dysregulation and CRC, and demonstrated the feasibility of the gut microbiota to diagnose cancer. The bacteria s__metagenome_g__Lachnospiraceae_ND3007_group, s__Escherichia_coli_g__Escherichia-Shigella and s__unclassified_g__Prevotella were key biomarkers for CRC.PMID:37288545 | DOI:10.1099/jmm.0.001699 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Fang Lu Ting Lei Jie Zhou Hao Liang Ping Cui Taiping Zuo Li Ye Hui Chen Jiegang Huang Source Type: research
Impact of the COVID-19 restrictions on the epidemiology of < em > Cryptosporidium < /em > spp. in England and Wales, 2015-2021: a time series analysis
Conclusion. C. hominis cases almost entirely ceased post-restrictions implementation, reinforcing that foreign travel seeds infections. C. parvum incidence fell sharply but recovered post-restrictions implementation, consistent with relaxation of restrictions. Future exceedance reporting for C. hominis should exclude the post-restriction implementation period but retain it for C. parvum (except the first 6 weeks post-restrictions implementation). Infection prevention and control advice should be improved for people with gastrointestinal illness (GI) symptoms to ensure hand hygiene and swimming pool avoidance.PMID:37288574 ...
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: James P Adamson Rachel M Chalmers Daniel Rh Thomas Kristin Elwin Guy Robinson Alicia Barrasa Source Type: research
Detection of multiple extensively-drug resistant hypervirulent < em > Klebsiella pneumoniae < /em > clones from patients with ventilator-associated pneumonia in Egypt
Conclusion. This study highlights the dominance and clonal spread of XDR-hvKP strains at Assiut University Hospital in Egypt. Physicians should be aware of the increased risk of hvKP induced-VAP and support further epidemiologic studies.PMID:37288576 | DOI:10.1099/jmm.0.001701 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Hadeel Elzeny Wegdan Mohamed Enas Daef Omnia El-Badawy Lamiaa Shaaban Naglaa S Osman Safy Hadiya Sherine Aly Source Type: research
Serotypes and antimicrobial resistance of < em > Streptococcus pneumoniae < /em > in children under 5 years of age pre- and post-pneumococcal conjugate vaccine introduction in Paraguay
Conclusion. A change in the circulating serotypes and antimicrobial resistance to certain antibiotics was observed. Non-vaccine serotype circulation and multidrug resistance may compromise the success of the conjugate vaccines.PMID:37289483 | DOI:10.1099/jmm.0.001700 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Mar ía Eugenia León Margarita Samudio An íbal Kawabata Minako Nagai Liliana Rojas Noem í Zárate Juan Irala Myrian Leguizam ón Gloria G ómez Juana Ortellado Raquel Blasco Rossana Franco Gustavo Chamorro Source Type: research
Effect of dextransucrase antibodies on biofilm formation and certain cariogenic activities in < em > Streptococcus mutans < /em >
Conclusions. These findings suggest that antibodies raised against dextransucrase exhibit a profound inhibitory effect on biofilm formation and vital cariogenic factors of S. mutans, which supports the contention that dextransucrase could be a promising antigen to study for its anticariogenic potential.PMID:37289487 | DOI:10.1099/jmm.0.001696 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Shabeer Ahmad Rather Abid Majeed Lakhvinder Singh Alka Bhatia Sukesh Chander Sharma Akhtar Mahmood Source Type: research
Characterisation of key genotypic and phenotypic traits of clinical cystic fibrosis < em > Staphylococcus aureus < /em > isolates
Conclusion. There is huge variation in genetic and phenotypic capabilities of S. aureus strains. Further studies on how these may differ in relation to other species in the CF lung may give insight into inter-species interactions.PMID:37289488 | DOI:10.1099/jmm.0.001703 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Micaela Mossop Luca Robinson Jhih-Hang Jiang Anton Y Peleg Luke V Blakeway Nenad Macesic Audrey Perry Stephen Bourke Fatima R Ulhuq Tracy Palmer Source Type: research
Using gut microbiota as a diagnostic tool for colorectal cancer: machine learning techniques reveal promising results
Conclusions. Our results suggested an association between gut microbiota dysregulation and CRC, and demonstrated the feasibility of the gut microbiota to diagnose cancer. The bacteria s__metagenome_g__Lachnospiraceae_ND3007_group, s__Escherichia_coli_g__Escherichia-Shigella and s__unclassified_g__Prevotella were key biomarkers for CRC.PMID:37288545 | DOI:10.1099/jmm.0.001699 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Fang Lu Ting Lei Jie Zhou Hao Liang Ping Cui Taiping Zuo Li Ye Hui Chen Jiegang Huang Source Type: research
Impact of the COVID-19 restrictions on the epidemiology of < em > Cryptosporidium < /em > spp. in England and Wales, 2015-2021: a time series analysis
Conclusion. C. hominis cases almost entirely ceased post-restrictions implementation, reinforcing that foreign travel seeds infections. C. parvum incidence fell sharply but recovered post-restrictions implementation, consistent with relaxation of restrictions. Future exceedance reporting for C. hominis should exclude the post-restriction implementation period but retain it for C. parvum (except the first 6 weeks post-restrictions implementation). Infection prevention and control advice should be improved for people with gastrointestinal illness (GI) symptoms to ensure hand hygiene and swimming pool avoidance.PMID:37288574 ...
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: James P Adamson Rachel M Chalmers Daniel Rh Thomas Kristin Elwin Guy Robinson Alicia Barrasa Source Type: research
Detection of multiple extensively-drug resistant hypervirulent < em > Klebsiella pneumoniae < /em > clones from patients with ventilator-associated pneumonia in Egypt
Conclusion. This study highlights the dominance and clonal spread of XDR-hvKP strains at Assiut University Hospital in Egypt. Physicians should be aware of the increased risk of hvKP induced-VAP and support further epidemiologic studies.PMID:37288576 | DOI:10.1099/jmm.0.001701 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Hadeel Elzeny Wegdan Mohamed Enas Daef Omnia El-Badawy Lamiaa Shaaban Naglaa S Osman Safy Hadiya Sherine Aly Source Type: research
Serotypes and antimicrobial resistance of < em > Streptococcus pneumoniae < /em > in children under 5 years of age pre- and post-pneumococcal conjugate vaccine introduction in Paraguay
Conclusion. A change in the circulating serotypes and antimicrobial resistance to certain antibiotics was observed. Non-vaccine serotype circulation and multidrug resistance may compromise the success of the conjugate vaccines.PMID:37289483 | DOI:10.1099/jmm.0.001700 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Mar ía Eugenia León Margarita Samudio An íbal Kawabata Minako Nagai Liliana Rojas Noem í Zárate Juan Irala Myrian Leguizam ón Gloria G ómez Juana Ortellado Raquel Blasco Rossana Franco Gustavo Chamorro Source Type: research
Effect of dextransucrase antibodies on biofilm formation and certain cariogenic activities in < em > Streptococcus mutans < /em >
Conclusions. These findings suggest that antibodies raised against dextransucrase exhibit a profound inhibitory effect on biofilm formation and vital cariogenic factors of S. mutans, which supports the contention that dextransucrase could be a promising antigen to study for its anticariogenic potential.PMID:37289487 | DOI:10.1099/jmm.0.001696 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Shabeer Ahmad Rather Abid Majeed Lakhvinder Singh Alka Bhatia Sukesh Chander Sharma Akhtar Mahmood Source Type: research
Characterisation of key genotypic and phenotypic traits of clinical cystic fibrosis < em > Staphylococcus aureus < /em > isolates
Conclusion. There is huge variation in genetic and phenotypic capabilities of S. aureus strains. Further studies on how these may differ in relation to other species in the CF lung may give insight into inter-species interactions.PMID:37289488 | DOI:10.1099/jmm.0.001703 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2023 Category: Microbiology Authors: Micaela Mossop Luca Robinson Jhih-Hang Jiang Anton Y Peleg Luke V Blakeway Nenad Macesic Audrey Perry Stephen Bourke Fatima R Ulhuq Tracy Palmer Source Type: research
Lipid A modification-induced colistin-resistant < em > Klebsiella variicola < /em > from healthy adults
Conclusions. We found that colistin resistance in K. variicola was mediated by the modification of lipid A. Although the isolate was obtained from faecal samples of healthy adults, colistin-resistant K. variicola challenges public health as an opportunistic pathogen.PMID:37261959 | DOI:10.1099/jmm.0.001680 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 1, 2023 Category: Microbiology Authors: Sun Ju Kim Jeongwoo Jo Kwan Soo Ko Source Type: research
Unravelling the flexibility of < em > Mycobacterium tuberculosis: < /em > an escape way for the bacilli
J Med Microbiol. 2023 Jun;72(6). doi: 10.1099/jmm.0.001695.ABSTRACTThe persistence of Mycobacterium tuberculosis makes it difficult to eradicate the associated infection from the host. The flexible nature of mycobacteria and their ability to adapt to adverse host conditions give rise to different drug-tolerant phenotypes. Granuloma formation restricts nutrient supply, limits oxygen availability and exposes bacteria to a low pH environment, resulting in non-replicating bacteria. These non-replicating mycobacteria, which need high doses and long exposure to anti-tubercular drugs, are the root cause of lengthy chemotherapy. N...
Source: Journal of Medical Microbiology - June 1, 2023 Category: Microbiology Authors: Shashikanta Sau Arnab Roy Puja Kumari Agnivesh Sunil Kumar Santosh Kumar Guru Sandeep Sharma Nitin Pal Kalia Source Type: research
