Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India
This study reiterates the EV-D68 novel subclade B3 circulation in India and indicates the urgent need for structured EV-D68 surveillance in the country to describe the epidemiology.PMID:33999799 | DOI:10.1099/jmm.0.001356 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Ramachandran Erathodi Sanjay Sasidharanpillai Sabeena Sudandiradas Robin John T Shaji M P Jayakrishnan E K Kumar Suresh C J Michael S Aswathyraj Joseph Josmi Sheik Shahin Jayaram Anup Govindakarnavar Arunkumar Source Type: research

Difference in drug susceptibility distribution and clinical characteristics between < em > Mycobacterium avium < /em > and < em > Mycobacterium intracellulare < /em > lung diseases in Shanghai, China
Conclusions. The pulmonary disease caused by distinct MAC species had different antimicrobial susceptibility, symptoms, and radiographic findings.PMID:33999797 | DOI:10.1099/jmm.0.001358 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Weiping Wang Jinghui Yang Xiaocui Wu Baoshan Wan Hongxiu Wang Fangyou Yu Yinjuan Guo Source Type: research

Determination of incompatibility group plasmids and copy number of the < em > bla < /em > < sub > NDM-1 < /sub > gene in carbapenem-resistant < em > Klebsiella pneumoniae < /em > strains recovered from different hospitals in Kerman, Iran
Conclusion. The spread of NDM-1-producing K. pneumoniae strains that carry several plasmid replicon types increases the chance of horizontal transfer of antibiotic resistance genes in hospital settings. In this study, 10 different replicon types were identified. We could not find any relationship between the increase of MIC levels to imipenem and the copy numbers of bla NDM-1. Therefore, due to the identification of different replicon types in this study, the type and genetic characteristics of bla NDM-1-carrying plasmids, and other factors such as antibiotic selective pressure, probably affect the copy number of bla NDM-1...
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Sajad Aslani Somayeh Kiaei Ali Afgar Jos é Rubén Morones-Ramírez Hossein Alishah Aratboni Ashkan Faridi Luis Roberto Rivera-Mackintosh Davood Kalantar-Neyestanaki Source Type: research

Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India
This study reiterates the EV-D68 novel subclade B3 circulation in India and indicates the urgent need for structured EV-D68 surveillance in the country to describe the epidemiology.PMID:33999799 | DOI:10.1099/jmm.0.001356 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Ramachandran Erathodi Sanjay Sasidharanpillai Sabeena Sudandiradas Robin John T Shaji M P Jayakrishnan E K Kumar Suresh C J Michael S Aswathyraj Joseph Josmi Sheik Shahin Jayaram Anup Govindakarnavar Arunkumar Source Type: research

Difference in drug susceptibility distribution and clinical characteristics between < em > Mycobacterium avium < /em > and < em > Mycobacterium intracellulare < /em > lung diseases in Shanghai, China
Conclusions. The pulmonary disease caused by distinct MAC species had different antimicrobial susceptibility, symptoms, and radiographic findings.PMID:33999797 | DOI:10.1099/jmm.0.001358 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Weiping Wang Jinghui Yang Xiaocui Wu Baoshan Wan Hongxiu Wang Fangyou Yu Yinjuan Guo Source Type: research

Determination of incompatibility group plasmids and copy number of the < em > bla < /em > < sub > NDM-1 < /sub > gene in carbapenem-resistant < em > Klebsiella pneumoniae < /em > strains recovered from different hospitals in Kerman, Iran
Conclusion. The spread of NDM-1-producing K. pneumoniae strains that carry several plasmid replicon types increases the chance of horizontal transfer of antibiotic resistance genes in hospital settings. In this study, 10 different replicon types were identified. We could not find any relationship between the increase of MIC levels to imipenem and the copy numbers of bla NDM-1. Therefore, due to the identification of different replicon types in this study, the type and genetic characteristics of bla NDM-1-carrying plasmids, and other factors such as antibiotic selective pressure, probably affect the copy number of bla NDM-1...
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Sajad Aslani Somayeh Kiaei Ali Afgar Jos é Rubén Morones-Ramírez Hossein Alishah Aratboni Ashkan Faridi Luis Roberto Rivera-Mackintosh Davood Kalantar-Neyestanaki Source Type: research

Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India
This study reiterates the EV-D68 novel subclade B3 circulation in India and indicates the urgent need for structured EV-D68 surveillance in the country to describe the epidemiology.PMID:33999799 | DOI:10.1099/jmm.0.001356 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Ramachandran Erathodi Sanjay Sasidharanpillai Sabeena Sudandiradas Robin John T Shaji M P Jayakrishnan E K Kumar Suresh C J Michael S Aswathyraj Joseph Josmi Sheik Shahin Jayaram Anup Govindakarnavar Arunkumar Source Type: research

Difference in drug susceptibility distribution and clinical characteristics between < em > Mycobacterium avium < /em > and < em > Mycobacterium intracellulare < /em > lung diseases in Shanghai, China
Conclusions. The pulmonary disease caused by distinct MAC species had different antimicrobial susceptibility, symptoms, and radiographic findings.PMID:33999797 | DOI:10.1099/jmm.0.001358 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Weiping Wang Jinghui Yang Xiaocui Wu Baoshan Wan Hongxiu Wang Fangyou Yu Yinjuan Guo Source Type: research

Determination of incompatibility group plasmids and copy number of the < em > bla < /em > < sub > NDM-1 < /sub > gene in carbapenem-resistant < em > Klebsiella pneumoniae < /em > strains recovered from different hospitals in Kerman, Iran
Conclusion. The spread of NDM-1-producing K. pneumoniae strains that carry several plasmid replicon types increases the chance of horizontal transfer of antibiotic resistance genes in hospital settings. In this study, 10 different replicon types were identified. We could not find any relationship between the increase of MIC levels to imipenem and the copy numbers of bla NDM-1. Therefore, due to the identification of different replicon types in this study, the type and genetic characteristics of bla NDM-1-carrying plasmids, and other factors such as antibiotic selective pressure, probably affect the copy number of bla NDM-1...
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Sajad Aslani Somayeh Kiaei Ali Afgar Jos é Rubén Morones-Ramírez Hossein Alishah Aratboni Ashkan Faridi Luis Roberto Rivera-Mackintosh Davood Kalantar-Neyestanaki Source Type: research

Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India
This study reiterates the EV-D68 novel subclade B3 circulation in India and indicates the urgent need for structured EV-D68 surveillance in the country to describe the epidemiology.PMID:33999799 | DOI:10.1099/jmm.0.001356 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Ramachandran Erathodi Sanjay Sasidharanpillai Sabeena Sudandiradas Robin John T Shaji M P Jayakrishnan E K Kumar Suresh C J Michael S Aswathyraj Joseph Josmi Sheik Shahin Jayaram Anup Govindakarnavar Arunkumar Source Type: research

Difference in drug susceptibility distribution and clinical characteristics between < em > Mycobacterium avium < /em > and < em > Mycobacterium intracellulare < /em > lung diseases in Shanghai, China
Conclusions. The pulmonary disease caused by distinct MAC species had different antimicrobial susceptibility, symptoms, and radiographic findings.PMID:33999797 | DOI:10.1099/jmm.0.001358 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Weiping Wang Jinghui Yang Xiaocui Wu Baoshan Wan Hongxiu Wang Fangyou Yu Yinjuan Guo Source Type: research

Determination of incompatibility group plasmids and copy number of the < em > bla < /em > < sub > NDM-1 < /sub > gene in carbapenem-resistant < em > Klebsiella pneumoniae < /em > strains recovered from different hospitals in Kerman, Iran
Conclusion. The spread of NDM-1-producing K. pneumoniae strains that carry several plasmid replicon types increases the chance of horizontal transfer of antibiotic resistance genes in hospital settings. In this study, 10 different replicon types were identified. We could not find any relationship between the increase of MIC levels to imipenem and the copy numbers of bla NDM-1. Therefore, due to the identification of different replicon types in this study, the type and genetic characteristics of bla NDM-1-carrying plasmids, and other factors such as antibiotic selective pressure, probably affect the copy number of bla NDM-1...
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Sajad Aslani Somayeh Kiaei Ali Afgar Jos é Rubén Morones-Ramírez Hossein Alishah Aratboni Ashkan Faridi Luis Roberto Rivera-Mackintosh Davood Kalantar-Neyestanaki Source Type: research

Genetic analysis of Enterovirus D68 associated with pneumonia in children from South India
This study reiterates the EV-D68 novel subclade B3 circulation in India and indicates the urgent need for structured EV-D68 surveillance in the country to describe the epidemiology.PMID:33999799 | DOI:10.1099/jmm.0.001356 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2021 Category: Microbiology Authors: Ramachandran Erathodi Sanjay Sasidharanpillai Sabeena Sudandiradas Robin John T Shaji M P Jayakrishnan E K Kumar Suresh C J Michael S Aswathyraj Joseph Josmi Sheik Shahin Jayaram Anup Govindakarnavar Arunkumar Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens
J Med Microbiol. 2021 May;70(5). doi: 10.1099/jmm.0.001363.ABSTRACTAntimicrobial resistance (AMR) is one of the greatest global health challenges of modern times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of antibiotics and increases both the morbidity and the mortality associated with bacterial infections. Despite this growing risk, few antibiotics with a novel mode of action are being produced, leading to a lack of antibiotics that can effectively treat bacterial infections with AMR. Metals have a history of antibacterial use but upon the discovery of antibiotics, often became overlo...
Source: Journal of Medical Microbiology - May 7, 2021 Category: Microbiology Authors: Andris Evans Kevin A Kavanagh Source Type: research

A longitudinal study of antibody responses to selected host antigens in rheumatic fever and rheumatic heart disease
Conclusion. Our findings of antibody responses against host proteins support the multistep hypothesis in the development of rheumatic carditis. The differential kinetics of serum antibody responses against S2 peptides may have potential use as markers of ongoing cardiac damage that can be used to monitor patients with ARF/RHD.PMID:33956590 | DOI:10.1099/jmm.0.001355 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 6, 2021 Category: Microbiology Authors: Nuzhat Z Surve Prafulla G Kerkar Chandrahas T Deshmukh Milind Y Nadkar Preeti R Mehta Natkunam Ketheesan Kadaba S Sriprakash Mohan G Karmarkar Source Type: research

Impact of different SARS-CoV-2 assays on laboratory turnaround time
Conclusion. This work shows that the combination of high-throughput systems and rapid tests allows the efficient processing of a large number of tests with a short TAT. In addition, the use of a custom platform allowed the quick implementation of an in-house test when commercial assays were not yet available.PMID:33956591 | DOI:10.1099/jmm.0.001280 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 6, 2021 Category: Microbiology Authors: Bastian Marquis Onya Opota Katia Jaton Gilbert Greub Source Type: research

A longitudinal study of antibody responses to selected host antigens in rheumatic fever and rheumatic heart disease
Conclusion. Our findings of antibody responses against host proteins support the multistep hypothesis in the development of rheumatic carditis. The differential kinetics of serum antibody responses against S2 peptides may have potential use as markers of ongoing cardiac damage that can be used to monitor patients with ARF/RHD.PMID:33956590 | DOI:10.1099/jmm.0.001355 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 6, 2021 Category: Microbiology Authors: Nuzhat Z Surve Prafulla G Kerkar Chandrahas T Deshmukh Milind Y Nadkar Preeti R Mehta Natkunam Ketheesan Kadaba S Sriprakash Mohan G Karmarkar Source Type: research

Impact of different SARS-CoV-2 assays on laboratory turnaround time
Conclusion. This work shows that the combination of high-throughput systems and rapid tests allows the efficient processing of a large number of tests with a short TAT. In addition, the use of a custom platform allowed the quick implementation of an in-house test when commercial assays were not yet available.PMID:33956591 | DOI:10.1099/jmm.0.001280 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 6, 2021 Category: Microbiology Authors: Bastian Marquis Onya Opota Katia Jaton Gilbert Greub Source Type: research

Effects of calcineurin inhibitors, cyclosporine A and tacrolimus (FK506), on the activity of antifungal drugs against < em > Candida < /em > spp
Conclusion. Synergistic interactions in the combinations of TAC or CsA with antifungal drugs, except for AMB, in many concentrations was found to be promising in terms of the treatment of patients with fungal infections.PMID:33915075 | DOI:10.1099/jmm.0.001354 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 29, 2021 Category: Microbiology Authors: S ümeyye Şen Kaya Nuri Kiraz Ay şe Bariş Deniz Turan Yasemin Öz İlknur Dağ G ökhan Aygün Source Type: research

Effects of calcineurin inhibitors, cyclosporine A and tacrolimus (FK506), on the activity of antifungal drugs against < em > Candida < /em > spp
Conclusion. Synergistic interactions in the combinations of TAC or CsA with antifungal drugs, except for AMB, in many concentrations was found to be promising in terms of the treatment of patients with fungal infections.PMID:33915075 | DOI:10.1099/jmm.0.001354 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 29, 2021 Category: Microbiology Authors: S ümeyye Şen Kaya Nuri Kiraz Ay şe Bariş Deniz Turan Yasemin Öz İlknur Dağ G ökhan Aygün Source Type: research

Effects of calcineurin inhibitors, cyclosporine A and tacrolimus (FK506), on the activity of antifungal drugs against < em > Candida < /em > spp
Conclusion. Synergistic interactions in the combinations of TAC or CsA with antifungal drugs, except for AMB, in many concentrations was found to be promising in terms of the treatment of patients with fungal infections.PMID:33915075 | DOI:10.1099/jmm.0.001354 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 29, 2021 Category: Microbiology Authors: S ümeyye Şen Kaya Nuri Kiraz Ay şe Bariş Deniz Turan Yasemin Öz İlknur Dağ G ökhan Aygün Source Type: research

Effects of calcineurin inhibitors, cyclosporine A and tacrolimus (FK506), on the activity of antifungal drugs against < em > Candida < /em > spp
Conclusion. Synergistic interactions in the combinations of TAC or CsA with antifungal drugs, except for AMB, in many concentrations was found to be promising in terms of the treatment of patients with fungal infections.PMID:33915075 | DOI:10.1099/jmm.0.001354 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 29, 2021 Category: Microbiology Authors: S ümeyye Şen Kaya Nuri Kiraz Ay şe Bariş Deniz Turan Yasemin Öz İlknur Dağ G ökhan Aygün Source Type: research

Effects of calcineurin inhibitors, cyclosporine A and tacrolimus (FK506), on the activity of antifungal drugs against < em > Candida < /em > spp
Conclusion. Synergistic interactions in the combinations of TAC or CsA with antifungal drugs, except for AMB, in many concentrations was found to be promising in terms of the treatment of patients with fungal infections.PMID:33915075 | DOI:10.1099/jmm.0.001354 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 29, 2021 Category: Microbiology Authors: S ümeyye Şen Kaya Nuri Kiraz Ay şe Bariş Deniz Turan Yasemin Öz İlknur Dağ G ökhan Aygün Source Type: research

Lipopolysaccharide from biofilm-forming < em > Pseudomonas aeruginosa < /em > PAO1 induces macrophage hyperinflammatory responses
Conclusion. The presented in vitro study indicates that LPS derived from biofilm-forming PAO1 induces enhanced M1 polarization in human and murine macrophage cell lines than LPS from planktonic PAO1.PMID:33909550 | DOI:10.1099/jmm.0.001352 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 28, 2021 Category: Microbiology Authors: Sufei Wang Dandan Xiang Fangbing Tian Ming Ni Source Type: research

Whole genome sequencing of a clinical drug resistant < em > Candida albicans < /em > isolate reveals known and novel mutations in genes involved in resistance acquisition mechanisms
This study aims at determining point mutations in genes known to be involved in resistance acquisition and correlating resistance to virulence and ergosterol content in the azole resistant C. albicans isolate CA77 from Lebanon. This pilot study is the first of its kind to be implemented in Lebanon. We carried out whole genome sequencing of the azole resistant C. albicans isolate CA77 and examined 18 genes involved in antifungal resistance. To correlate genotype to phenotype, we evaluated the virulence potential of this isolate by injecting it into BALB/c mice and we quantified membrane ergosterol. Whole genome sequencing r...
Source: Journal of Medical Microbiology - April 28, 2021 Category: Microbiology Authors: Roy A Khalaf Nour Fattouh Matej Medvecky Jaroslav Hrabak Source Type: research

Rapid macrolide and amikacin resistance testing for < em > Mycobacterium abscessus < /em > in people with cystic fibrosis
Conclusion. Using the molecular methods described here, results for health care providers or researchers could be available days or weeks earlier than is currently possible via culture-based antibiotic susceptibility testing.PMID:33909552 | DOI:10.1099/jmm.0.001349 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 28, 2021 Category: Microbiology Authors: Amanda Bordin Sushil Pandey Christopher Coulter Melanie Syrmis Carolyn Pardo Hazel Hackett Scott C Bell Claire E Wainwright Graeme R Nimmo Amy V Jennison Julia E Clark David M Whiley Source Type: research

Lipopolysaccharide from biofilm-forming < em > Pseudomonas aeruginosa < /em > PAO1 induces macrophage hyperinflammatory responses
Conclusion. The presented in vitro study indicates that LPS derived from biofilm-forming PAO1 induces enhanced M1 polarization in human and murine macrophage cell lines than LPS from planktonic PAO1.PMID:33909550 | DOI:10.1099/jmm.0.001352 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 28, 2021 Category: Microbiology Authors: Sufei Wang Dandan Xiang Fangbing Tian Ming Ni Source Type: research

Whole genome sequencing of a clinical drug resistant < em > Candida albicans < /em > isolate reveals known and novel mutations in genes involved in resistance acquisition mechanisms
This study aims at determining point mutations in genes known to be involved in resistance acquisition and correlating resistance to virulence and ergosterol content in the azole resistant C. albicans isolate CA77 from Lebanon. This pilot study is the first of its kind to be implemented in Lebanon. We carried out whole genome sequencing of the azole resistant C. albicans isolate CA77 and examined 18 genes involved in antifungal resistance. To correlate genotype to phenotype, we evaluated the virulence potential of this isolate by injecting it into BALB/c mice and we quantified membrane ergosterol. Whole genome sequencing r...
Source: Journal of Medical Microbiology - April 28, 2021 Category: Microbiology Authors: Roy A Khalaf Nour Fattouh Matej Medvecky Jaroslav Hrabak Source Type: research

Rapid macrolide and amikacin resistance testing for < em > Mycobacterium abscessus < /em > in people with cystic fibrosis
Conclusion. Using the molecular methods described here, results for health care providers or researchers could be available days or weeks earlier than is currently possible via culture-based antibiotic susceptibility testing.PMID:33909552 | DOI:10.1099/jmm.0.001349 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 28, 2021 Category: Microbiology Authors: Amanda Bordin Sushil Pandey Christopher Coulter Melanie Syrmis Carolyn Pardo Hazel Hackett Scott C Bell Claire E Wainwright Graeme R Nimmo Amy V Jennison Julia E Clark David M Whiley Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research

Co-infection in critically ill patients with COVID-19: an observational cohort study from England
Conclusion. We found limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19, but a high rate of Gram-negative infection acquired during ICU stay.PMID:33861190 | DOI:10.1099/jmm.0.001350 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Vadsala Baskaran Hannah Lawrence Louise E Lansbury Karmel Webb Shahideh Safavi Nurul I Zainuddin Tausif Huq Charlotte Eggleston Jayne Ellis Clare Thakker Bethan Charles Sara Boyd Tom Williams Claire Phillips Ethan Redmore Sarah Platt Eve Hamilton Andrew B Source Type: research

Clinical characteristics and antibody response to SARS-CoV-2 spike 1 protein using VITROS Anti-SARS-CoV-2 antibody tests in COVID-19 patients in Japan
Conclusion. VITROS Anti-SARS-CoV-2 total and IgG assays will be useful as supporting diagnostic and surveillance tools and for evaluation of humoral immune response to COVID-19. Optimal prediction of disease prognosis is made from considering both clinical history and laboratory findings.PMID:33861191 | DOI:10.1099/jmm.0.001291 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - April 16, 2021 Category: Microbiology Authors: Mayu Nagura-Ikeda Kazuo Imai Katsumi Kubota Sakiko Noguchi Yutaro Kitagawa Masaru Matsuoka Sakiko Tabata Kazuyasu Miyoshi Toshimitsu Ito Kaku Tamura Takuya Maeda Source Type: research