Analysis of possible pathways on the mechanism of action of minocycline and doxycycline against strains of < em > Candida < /em > spp. resistant to fluconazole
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001759.ABSTRACTSpecies of the genus Candida, characterized as commensals of the human microbiota, are opportunistic pathogens capable of generating various types of infections with high associated costs. Considering the limited pharmacological arsenal and the emergence of antifungal-resistant strains, the repositioning of drugs is a strategy used to search for new therapeutic alternatives, in which minocycline and doxycycline have been evaluated as potential candidates. Thus, the objective was to evaluate the in vitro antifungal activity of two tetracyclines, minocycline...
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Cec ília Rocha da Silva Maria Janielly Castelo Branco Silveira Giulia Caetano Soares Claudia Roberta de Andrade Vit ória Pessoa de Farias Cabral L ívia Gurgel do Amaral Valente Sá Daniel Sampaio Rodrigues Lara Elloyse Almeida Moreira Amanda Dias Barbo Source Type: research
Avian reovirus: a furious and fast evolving pathogen
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001761.ABSTRACTAvian reoviruses (ARVs) have a significant economic impact on the poultry industry, affecting commercial and backyard flocks. Spread feco-orally, or vertically, many do not cause morbidity, but pathogenic strains can contribute to several diseases, including tenosynovitis/arthritis, which is clinically the most significant. The last decade has seen a surge in cases in the US, and due to ongoing evolution, seven genotypic clusters have now been identified. Control efforts include strict biosecurity and vaccination with commercial and autogenous vaccines. Re...
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Sofia Egana-Labrin Andrew J Broadbent Source Type: research
Foodborne antimicrobial resistance (AMR) research and surveillance in the UK: priorities identified through the Food Standards Agency's AMR programme review (2023)
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001753.NO ABSTRACTPMID:37801024 | DOI:10.1099/jmm.0.001753 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Henry Nicholls Bobby Kainth Paul Cook Rick Mumford Charles Keevil Roberto La Ragione Eric Threlfall David McDowell Kathryn Callaghan Source Type: research
Corrigendum: The characterisation of antimicrobial resistant < em > Escherichia coli < /em > from dairy calves
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001764.NO ABSTRACTPMID:37801009 | DOI:10.1099/jmm.0.001764 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Merning Mwenifumbo Adrian L Cookson Shengguo Zhao Ahmed Fayaz A Springer Browne Jackie Benschop Sara A Burgess Source Type: research
Rapid response of a public health reference laboratory to the COVID-19 pandemic
Conclusion. IAL was able to rapidly implement a new laboratory structure to support the processing of an enormous number of samples for diagnosis of COVID-19, outlining strategies to carry out work with quality, using different RT-qPCR protocols.PMID:37801010 | DOI:10.1099/jmm.0.001757 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Juliana Maira Watanabe Pinhata Angela Pires Brandao Daniela Leite Rosangela Siqueira de Oliveira Lucila Okuyama Fukasawa Maria Gisele Gon çalves Juliana Mariotti Guerra Leonardo Jos é Tadeu de Araujo Gina Ploeger Mansueli Lilian Beserra Santos Tarcilla Source Type: research
Analysis of possible pathways on the mechanism of action of minocycline and doxycycline against strains of < em > Candida < /em > spp. resistant to fluconazole
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001759.ABSTRACTSpecies of the genus Candida, characterized as commensals of the human microbiota, are opportunistic pathogens capable of generating various types of infections with high associated costs. Considering the limited pharmacological arsenal and the emergence of antifungal-resistant strains, the repositioning of drugs is a strategy used to search for new therapeutic alternatives, in which minocycline and doxycycline have been evaluated as potential candidates. Thus, the objective was to evaluate the in vitro antifungal activity of two tetracyclines, minocycline...
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Cec ília Rocha da Silva Maria Janielly Castelo Branco Silveira Giulia Caetano Soares Claudia Roberta de Andrade Vit ória Pessoa de Farias Cabral L ívia Gurgel do Amaral Valente Sá Daniel Sampaio Rodrigues Lara Elloyse Almeida Moreira Amanda Dias Barbo Source Type: research
Avian reovirus: a furious and fast evolving pathogen
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001761.ABSTRACTAvian reoviruses (ARVs) have a significant economic impact on the poultry industry, affecting commercial and backyard flocks. Spread feco-orally, or vertically, many do not cause morbidity, but pathogenic strains can contribute to several diseases, including tenosynovitis/arthritis, which is clinically the most significant. The last decade has seen a surge in cases in the US, and due to ongoing evolution, seven genotypic clusters have now been identified. Control efforts include strict biosecurity and vaccination with commercial and autogenous vaccines. Re...
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Sofia Egana-Labrin Andrew J Broadbent Source Type: research
Foodborne antimicrobial resistance (AMR) research and surveillance in the UK: priorities identified through the Food Standards Agency's AMR programme review (2023)
J Med Microbiol. 2023 Oct;72(10). doi: 10.1099/jmm.0.001753.NO ABSTRACTPMID:37801024 | DOI:10.1099/jmm.0.001753 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 6, 2023 Category: Microbiology Authors: Henry Nicholls Bobby Kainth Paul Cook Rick Mumford Charles Keevil Roberto La Ragione Eric Threlfall David McDowell Kathryn Callaghan Source Type: research
Efficacy of ceftobiprole in a murine model of bacteremia and disseminated infection
Conclusion. These results suggest that treatment with ceftobiprole using a 500 mg q8h dosing regimen studied in several successful phase three trials, has potential as an antibiotic therapy to treat bacteremia and associated disseminated infections caused by either methicillin-susceptible or methicillin-resistant strains of S. aureus.PMID:37791651 | DOI:10.1099/jmm.0.001755 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 4, 2023 Category: Microbiology Authors: Charlotte Cumper Claire Richards Jennifer Smart Karine Litherland Mark Jones Source Type: research
Efficacy of ceftobiprole in a murine model of bacteremia and disseminated infection
Conclusion. These results suggest that treatment with ceftobiprole using a 500 mg q8h dosing regimen studied in several successful phase three trials, has potential as an antibiotic therapy to treat bacteremia and associated disseminated infections caused by either methicillin-susceptible or methicillin-resistant strains of S. aureus.PMID:37791651 | DOI:10.1099/jmm.0.001755 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - October 4, 2023 Category: Microbiology Authors: Charlotte Cumper Claire Richards Jennifer Smart Karine Litherland Mark Jones Source Type: research
Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials
Conclusions. Probiotics have a therapeutic role in IBS. However, the effect of different probiotics varies. The minimal effective dose of probiotics may be 109 c.f.u./day. With appropriate probiotic formula, the therapeutic effect can occur at 4 weeks. These data provide a basis for further research on the optimal probiotic therapy in IBS.PMID:37772692 | DOI:10.1099/jmm.0.001758 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - September 29, 2023 Category: Microbiology Authors: Wen Xue Zhang Lu Bo Shi Min Si Zhou Jing Wu Hai Yun Shi Source Type: research
Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials
Conclusions. Probiotics have a therapeutic role in IBS. However, the effect of different probiotics varies. The minimal effective dose of probiotics may be 109 c.f.u./day. With appropriate probiotic formula, the therapeutic effect can occur at 4 weeks. These data provide a basis for further research on the optimal probiotic therapy in IBS.PMID:37772692 | DOI:10.1099/jmm.0.001758 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - September 29, 2023 Category: Microbiology Authors: Wen Xue Zhang Lu Bo Shi Min Si Zhou Jing Wu Hai Yun Shi Source Type: research
Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials
Conclusions. Probiotics have a therapeutic role in IBS. However, the effect of different probiotics varies. The minimal effective dose of probiotics may be 109 c.f.u./day. With appropriate probiotic formula, the therapeutic effect can occur at 4 weeks. These data provide a basis for further research on the optimal probiotic therapy in IBS.PMID:37772692 | DOI:10.1099/jmm.0.001758 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - September 29, 2023 Category: Microbiology Authors: Wen Xue Zhang Lu Bo Shi Min Si Zhou Jing Wu Hai Yun Shi Source Type: research
Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials
Conclusions. Probiotics have a therapeutic role in IBS. However, the effect of different probiotics varies. The minimal effective dose of probiotics may be 109 c.f.u./day. With appropriate probiotic formula, the therapeutic effect can occur at 4 weeks. These data provide a basis for further research on the optimal probiotic therapy in IBS.PMID:37772692 | DOI:10.1099/jmm.0.001758 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - September 29, 2023 Category: Microbiology Authors: Wen Xue Zhang Lu Bo Shi Min Si Zhou Jing Wu Hai Yun Shi Source Type: research
Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials
Conclusions. Probiotics have a therapeutic role in IBS. However, the effect of different probiotics varies. The minimal effective dose of probiotics may be 109 c.f.u./day. With appropriate probiotic formula, the therapeutic effect can occur at 4 weeks. These data provide a basis for further research on the optimal probiotic therapy in IBS.PMID:37772692 | DOI:10.1099/jmm.0.001758 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - September 29, 2023 Category: Microbiology Authors: Wen Xue Zhang Lu Bo Shi Min Si Zhou Jing Wu Hai Yun Shi Source Type: research
