Three-dimensional chromatin architecture in plants - General features and novelties
We present an overview on plant 3D genome organizational features that resemble those in animals and highlight facets that have only been observed in plants to date.PMID:37562220 | DOI:10.1016/j.ejcb.2023.151344 (Source: European Journal of Cell Biology)
Source: European Journal of Cell Biology - August 10, 2023 Category: Cytology Authors: Edouard Tourdot Stefan Grob Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells
Eur J Cell Biol. 2023 Jul 23;102(3):151343. doi: 10.1016/j.ejcb.2023.151343. Online ahead of print.ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse. Nuclear deformability plays a critical role in cancer cell invasion through confined spaces; however, the direct impact of epigenetic changes on the nuclear deformability of leukemic cells remains unclear. Here, we characterized how 3D collagen matrix conditions induced H3K4 methylation in ALL cell lines and clinical samples. We used specific shRNA and chemical...
Source: European Journal of Cell Biology - July 26, 2023 Category: Cytology Authors: Raquel Gonz ález-Novo Ana de Lope-Planelles Mar ía Pilar Cruz Rodríguez África González-Murillo Elena Madrazo David Acitores Mario Garc ía de Lacoba Manuel Ram írez Javier Redondo-Mu ñoz Source Type: research
Leptin deficiency impairs adipogenesis and browning response in mouse mesenchymal progenitors
Eur J Cell Biol. 2023 Jul 13;102(3):151342. doi: 10.1016/j.ejcb.2023.151342. Online ahead of print.ABSTRACTAlthough phenotypically different, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) are able to produce heat through non-shivering thermogenesis due to the presence of mitochondrial uncoupling protein 1 (UCP1). The appearance of thermogenically active beige adipocytes in iWAT is known as browning. Both brown and beige cells originate from mesenchymal stem cells (MSCs), and in culture conditions a browning response can be induced with hypothermia (i.e. 32 °C) during which nuclear leptin immunodetect...
Source: European Journal of Cell Biology - July 19, 2023 Category: Cytology Authors: Ksenija Velickovic Hilda Anaid Lugo Leija Bojana Kosic Harold Sacks Michael E Symonds Virginie Sottile Source Type: research
Leptin deficiency impairs adipogenesis and browning response in mouse mesenchymal progenitors
Eur J Cell Biol. 2023 Jul 13;102(3):151342. doi: 10.1016/j.ejcb.2023.151342. Online ahead of print.ABSTRACTAlthough phenotypically different, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) are able to produce heat through non-shivering thermogenesis due to the presence of mitochondrial uncoupling protein 1 (UCP1). The appearance of thermogenically active beige adipocytes in iWAT is known as browning. Both brown and beige cells originate from mesenchymal stem cells (MSCs), and in culture conditions a browning response can be induced with hypothermia (i.e. 32 °C) during which nuclear leptin immunodetect...
Source: European Journal of Cell Biology - July 19, 2023 Category: Cytology Authors: Ksenija Velickovic Hilda Anaid Lugo Leija Bojana Kosic Harold Sacks Michael E Symonds Virginie Sottile Source Type: research
Leptin deficiency impairs adipogenesis and browning response in mouse mesenchymal progenitors
Eur J Cell Biol. 2023 Jul 13;102(3):151342. doi: 10.1016/j.ejcb.2023.151342. Online ahead of print.ABSTRACTAlthough phenotypically different, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) are able to produce heat through non-shivering thermogenesis due to the presence of mitochondrial uncoupling protein 1 (UCP1). The appearance of thermogenically active beige adipocytes in iWAT is known as browning. Both brown and beige cells originate from mesenchymal stem cells (MSCs), and in culture conditions a browning response can be induced with hypothermia (i.e. 32 °C) during which nuclear leptin immunodetect...
Source: European Journal of Cell Biology - July 19, 2023 Category: Cytology Authors: Ksenija Velickovic Hilda Anaid Lugo Leija Bojana Kosic Harold Sacks Michael E Symonds Virginie Sottile Source Type: research
