A year in review: brain barriers and brain fluids research in 2022
This aim of this editorial is to highlight progress made in brain barrier and brain fluid research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers (choroid plexus and meninge... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 21, 2023 Category: Neurology Authors: Richard F. Keep, Hazel C. Jones, Mark G. Hamilton and Lester R. Drewes Tags: Editorial Source Type: research
Genetic disorders and genetic manipulation at the blood-brain barriers
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 20, 2023 Category: Neurology Authors: Richard F. Keep, Hazel C. Jones and Lester R. Drewes Tags: Editorial Source Type: research
Abstracts from the International Symposium “Signal Transduction at the Blood–Brain Barriers” 2022
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 19, 2023 Category: Neurology Tags: Meeting Abstracts Source Type: research
Central nervous system insulin signaling can influence the rate of insulin influx into brain
Insulin transport across the blood-brain barrier (BBB) is a highly regulated, saturable process, known to be affected by many peripheral substrates including insulin itself and triglycerides. This is in contra... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 19, 2023 Category: Neurology Authors: Van Nguyen, Peter Thomas, Sarah Pemberton, Alice Babin, Cassidy Noonan, Riley Weaver, William A. Banks and Elizabeth M. Rhea Tags: Research Source Type: research
Movement of cerebrospinal fluid tracer into brain parenchyma and outflow to nasal mucosa is reduced at 24 h but not 2 weeks post-stroke in mice
Recent data indicates that cerebrospinal fluid (CSF) dynamics are disturbed after stroke. Our lab has previously shown that intracranial pressure rises dramatically 24 h after experimental stroke and that this... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 11, 2023 Category: Neurology Authors: K. E. Warren, K. G. Coupland, R. J. Hood, L. Kang, F. R. Walker and N. J. Spratt Tags: Research Source Type: research
Direct association with the vascular basement membrane is a frequent feature of myelinating oligodendrocytes in the neocortex
Oligodendrocyte lineage cells interact with the vasculature in the gray matter. Physical and functional interactions between blood vessels and oligodendrocyte precursor cells play an essential role in both the... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 3, 2023 Category: Neurology Authors: Justine S. C. Palhol, Maddalena Balia, Fernando S ánchez-Román Terán, Mélody Labarchède, Etienne Gontier and Arne Battefeld Tags: Research Source Type: research
Filter exchange imaging with crusher gradient modelling detects increased blood –brain barrier water permeability in response to mild lung infection
Blood –brain barrier (BBB) dysfunction occurs in many brain diseases, and there is increasing evidence to suggest that it is an early process in dementia which may be exacerbated by peripheral infection. Filter... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - April 3, 2023 Category: Neurology Authors: Yolanda Ohene, William J. Harris, Elizabeth Powell, Nina W. Wycech, Katherine F. Smethers, Samo Lasi č, Kieron South, Graham Coutts, Andrew Sharp, Catherine B. Lawrence, Hervé Boutin, Geoff J. M. Parker, Laura M. Parkes and Ben R. Dickie Tags: Research Source Type: research
The CLDN5 gene at the blood-brain barrier in health and disease
The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and forms tight junctions which limit the passive diffusions of ions and solutes. The blood –brain barrier (BBB), composed of brain ... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 28, 2023 Category: Neurology Authors: Yosuke Hashimoto, Chris Greene, Arnold Munnich and Matthew Campbell Tags: Review Source Type: research
Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives
Despite greatly renewed interest concerning meningeal lymphatic function over recent years, the lymphatic structures of human dura mater have been less characterized. The available information derives exclusiv... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 28, 2023 Category: Neurology Authors: C ésar Luis Vera Quesada, Shreyas Balachandra Rao, Reidun Torp and Per Kristian Eide Tags: Research Source Type: research
Large-scale morphometry of the subarachnoid space of the optic nerve
The meninges, formed by dura, arachnoid and pia mater, cover the central nervous system and provide important barrier functions. Located between arachnoid and pia mater, the cerebrospinal fluid (CSF)-filled su... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 21, 2023 Category: Neurology Authors: Diego Rossinelli, Hanspeter Esriel Killer, Peter Meyer, Graham Knott, Gilles Fourestey, Vartan Kurtcuoglu, Corina Kohler, Philipp Gruber, Luca Remonda, Albert Neutzner and Jatta Berberat Tags: Research Source Type: research
Estimates of the permeability of extra-cellular pathways through the astrocyte endfoot sheath
Astrocyte endfoot processes are believed to cover all micro-vessels in the brain cortex and may play a significant role in fluid and substance transport into and out of the brain parenchyma. Detailed fluid mec... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 20, 2023 Category: Neurology Authors: Timo Koch, Vegard Vinje and Kent-Andr é Mardal Tags: Research Source Type: research
Morphological and mitochondrial changes in murine choroid plexus epithelial cells during healthy aging
Choroid plexuses (ChPs) are intraventricular structures mainly composed by specialized epithelial cells interconnected by tight junctions that establish the blood-cerebrospinal fluid (CSF) barrier. ChPs are es... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 14, 2023 Category: Neurology Authors: Valentina Scarpetta, Felipe Bodaleo, Chiara Salio, Amit Agarwal, Marco Sasso è-Pognetto and Annarita Patrizi Tags: Research Source Type: research
Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis
The mechanisms of cerebrospinal fluid (CSF) production by the ventricular choroid plexus (ChP) have not been fully deciphered. One prominent hypothesized mechanism is trans-epithelial water transport mediated ... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 13, 2023 Category: Neurology Authors: Pooya Razzaghi Khamesi, Vasileios Charitatos, Eva K. Heerfordt, Nanna MacAulay and Vartan Kurtcuoglu Tags: Research Source Type: research
Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion
In the cerebrospinal fluid (CSF) dynamics, the pulsations of cerebral arteries and brain is considered the main driving force for the reciprocating bidirectional CSF movements. However, measuring these complex... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 10, 2023 Category: Neurology Authors: Shigeki Yamada, Shinnosuke Hiratsuka, Tomohiro Otani, Satoshi Ii, Shigeo Wada, Marie Oshima, Kazuhiko Nozaki and Yoshiyuki Watanabe Tags: Research Source Type: research
Maternal e-cigarette use can disrupt postnatal blood-brain barrier (BBB) integrity and deteriorates motor, learning and memory function: influence of sex and age
Electronic nicotine delivery systems (ENDS), also commonly known as electronic cigarettes (e-cigs) are considered in most cases as a safer alternative to tobacco smoking and therefore have become extremely pop... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 10, 2023 Category: Neurology Authors: Sabrina Rahman Archie, Ali Ehsan Sifat, Yong Zhang, Heidi Villalba, Sejal Sharma, Saeideh Nozohouri and Thomas J. Abbruscato Tags: Research Source Type: research
