Microglia activated by microbial neuraminidase contributes to ependymal cell death
The administration of microbial neuraminidase into the brain ventricular cavities of rodents represents a model of acute aseptic neuroinflammation. Ependymal cell death and hydrocephalus are unique features of... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 23, 2021 Category: Neurology Authors: Mar ía del Mar Fernández-Arjona, Ana León-Rodríguez, María Dolores López-Ávalos and Jesús M. Grondona Tags: Research Source Type: research

Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas
Central nervous system diseases involving the parenchymal microvessels are frequently associated with a ‘microvasculopathy’, which includes different levels of neurovascular unit (NVU) dysfunction, including b... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 20, 2021 Category: Neurology Authors: Francesco Girolamo, Ignazio de Trizio, Mariella Errede, Giovanna Longo, Antonio d ’Amati and Daniela Virgintino Tags: Review Source Type: research

In vitro evaluation of cerebrospinal fluid velocity measurement in type I Chiari malformation: repeatability, reproducibility, and agreement using 2D phase contrast and 4D flow MRI
Phase contrast magnetic resonance imaging, PC MRI, is a valuable tool allowing for non-invasive quantification of CSF dynamics, but has lacked adoption in clinical practice for Chiari malformation diagnostics.... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 18, 2021 Category: Neurology Authors: Gwendolyn Williams, Suraj Thyagaraj, Audrey Fu, John Oshinski, Daniel Giese, Alexander C. Bunck, Eleonora Fornari, Francesco Santini, Mark Luciano, Francis Loth and Bryn A. Martin Tags: Research Source Type: research

Astrocyte-specific hypoxia-inducible factor 1 (HIF-1) does not disrupt the endothelial barrier during hypoxia in vitro
Astrocytes (AC) are essential for brain homeostasis. Much data suggests that AC support and protect the vascular endothelium, but increasing evidence indicates that during injury conditions they may lose their... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 18, 2021 Category: Neurology Authors: Julia Baumann, Chih-Chieh Tsao, Sheng-Fu Huang, Max Gassmann and Omolara O. Ogunshola Tags: Research Source Type: research

Variations in the cerebrospinal fluid dynamics of the American alligator (Alligator mississippiensis)
Studies of mammalian CSF dynamics have been focused on three things: paravascular flow, pressure and pulsatility, and “bulk” flow; and three (respective) potential motive forces have been identified: vasomotor... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - March 12, 2021 Category: Neurology Authors: Bruce A. Young, James Adams, Jonathan M. Beary, Kent-Andre Mardal, Robert Schneider and Tatyana Kondrashova Tags: Research Source Type: research