SCO-spondin, a giant matricellular protein that regulates cerebrospinal fluid activity
Cerebrospinal fluid is a clear fluid that occupies the ventricular and subarachnoid spaces within and around the brain and spinal cord. Cerebrospinal fluid is a dynamic signaling milieu that transports nutrien... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - October 2, 2021 Category: Neurology Authors: Vania Sep úlveda, Felipe Maurelia, Maryori González, Jaime Aguayo and Teresa Caprile Tags: Review Source Type: research
Activation of Frizzled-7 attenuates blood –brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice
Destruction of blood –brain barrier (BBB) is one of the main mechanisms of secondary brain injury following intracerebral hemorrhage (ICH). Frizzled-7 is a key protein expressed on the surface of endothelial ... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - September 26, 2021 Category: Neurology Authors: Wei He, Qin Lu, Prativa Sherchan, Lei Huang, Xin Hu, John H. Zhang, Haibin Dai and Jiping Tang Tags: Research Source Type: research
Investigating receptor-mediated antibody transcytosis using blood –brain barrier organoid arrays
The pathways that control protein transport across the blood –brain barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro, current models are not suitable fo... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - September 20, 2021 Category: Neurology Authors: Claire Simonneau, Martina Duschmal é, Alina Gavrilov, Nathalie Brandenberg, Sylke Hoehnel, Camilla Ceroni, Evodie Lassalle, Elena Kassianidou, Hendrik Knoetgen, Jens Niewoehner and Roberto Villaseñor Tags: Research Source Type: research
Interactions of brain, blood, and CSF: a novel mathematical model of cerebral edema
Previous models of intracranial pressure (ICP) dynamics have not included flow of cerebral interstitial fluid (ISF) and changes in resistance to its flow when brain swelling occurs. We sought to develop a math... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - September 16, 2021 Category: Neurology Authors: Omer Doron, Yuliya Zadka, Ofer Barnea and Guy Rosenthal Tags: Research Source Type: research
Response to the letter, entitled “Role of hemagglutinin esterase protein in neurological manifestation of COVID-19”
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - September 3, 2021 Category: Neurology Authors: Rashid Deane Tags: Letter to the Editor Source Type: research
The CXCL13/CXCR5-chemokine axis in neuroinflammation: evidence of CXCR5+CD4 T cell recruitment to CSF
C-X-C chemokine ligand 13 (CXCL13) is frequently elevated in cerebrospinal fluid (CSF) in a variety of inflammatory central nervous system (CNS) diseases, has been detected in meningeal B cell aggregates in br... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 26, 2021 Category: Neurology Authors: Christine Harrer, Ferdinand Otto, Georg Pilz, Elisabeth Haschke-Becher, Eugen Trinka, Wolfgang Hitzl, Peter Wipfler and Andrea Harrer Tags: Research Source Type: research
Impact of sex differences on thrombin-induced hydrocephalus and white matter injury: the role of neutrophils
Thrombin has been implicated in playing a role in hydrocephalus development following intraventricular hemorrhage (IVH). However, the mechanisms underlying the sex differences to the detrimental effects of thr... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 16, 2021 Category: Neurology Authors: Kang Peng, Sravanthi Koduri, Fan Xia, Feng Gao, Ya Hua, Richard F. Keep and Guohua Xi Tags: Research Source Type: research
Role of hemagglutinin esterase protein in neurological manifestation of COVID-19
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 16, 2021 Category: Neurology Authors: Milad Zandi, Hassan Karami and Saber Soltani Tags: Letter to the Editor Source Type: research
Incidental findings of typical iNPH imaging signs in asymptomatic subjects with subclinical cognitive decline
This study aimed to investigate the association of neuropsychological data with... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 14, 2021 Category: Neurology Authors: Doortje C. Engel, Lukas Pirpamer, Edith Hofer, Reinhold Schmidt and Cornelia Brendle Tags: Research Source Type: research
Similarities and differences in the localization, trafficking, and function of P-glycoprotein in MDR1-EGFP-transduced rat versus human brain capillary endothelial cell lines
In vitro models based on brain capillary endothelial cells (BCECs) are among the most versatile tools in blood –brain barrier research for testing drug penetration into the brain and how this is affected by eff... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 3, 2021 Category: Neurology Authors: Birthe Gericke, Saskia Borsdorf, Inka Wienb öker, Andreas Noack, Sandra Noack and Wolfgang Löscher Tags: Research Source Type: research
Imaging features associated with idiopathic normal pressure hydrocephalus have high specificity even when comparing with vascular dementia and atypical parkinsonism
Vascular dementia (VaD) and atypical parkinsonism often present with symptoms that can resemble idiopathic normal pressure hydrocephalus (iNPH) and enlarged cerebral ventricles, and can be challenging differen... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 29, 2021 Category: Neurology Authors: David F ällmar, Oliver Andersson, Lena Kilander, Malin Löwenmark, Dag Nyholm and Johan Virhammar Tags: Research Source Type: research
Characterization of the blood –brain barrier in genetically diverse laboratory mouse strains
Genetic variation in a population has an influence on the manifestation of monogenic as well as multifactorial disorders, with the underlying genetic contribution dependent on several interacting variants. Com... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 28, 2021 Category: Neurology Authors: Johanna Schaffenrath, Sheng-Fu Huang, Tania Wyss, Mauro Delorenzi and Annika Keller Tags: Research Source Type: research
A multicenter retrospective study of heterogeneous tissue aggregates obstructing ventricular catheters explanted from patients with hydrocephalus
Implantation of ventricular catheters (VCs) to drain cerebrospinal fluid (CSF) is a standard approach to treat hydrocephalus. VCs fail frequently due to tissue obstructing the lumen via the drainage holes. Mec... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 21, 2021 Category: Neurology Authors: Prashant Hariharan, Jeffrey Sondheimer, Alexandra Petroj, Jacob Gluski, Andrew Jea, William E. Whitehead, Sandeep Sood, Steven D. Ham, Brandon G. Rocque, Neena I. Marupudi, James P. McAllister II, David Limbrick, Marc R. Del Bigio and Carolyn A. Harris Tags: Research Source Type: research
SARS-CoV-2: is there neuroinvasion?
SARS-CoV-2, a coronavirus (CoV), is known to cause acute respiratory distress syndrome, and a number of non-respiratory complications, particularly in older male patients with prior health conditions, such as ... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 14, 2021 Category: Neurology Authors: Conor McQuaid, Molly Brady and Rashid Deane Tags: Review Source Type: research
The regulatory roles of motile cilia in CSF circulation and hydrocephalus
Cerebrospinal fluid (CSF) is an ultra-filtrated colorless brain fluid that circulates within brain spaces like the ventricular cavities, subarachnoid space, and the spine. Its continuous flow serves many prima... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 7, 2021 Category: Neurology Authors: Vijay Kumar, Zobia Umair, Shiv Kumar, Ravi Shankar Goutam, Soochul Park and Jaebong Kim Tags: Review Source Type: research
