Relationship between brain iron dynamics and blood-brain barrier function during childhood: a quantitative magnetic resonance imaging study
Mounting evidence suggests that the blood-brain barrier (BBB) plays an important role in the regulation of brain iron homeostasis in normal brain development, but these imaging profiles remain to be elucidated... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 17, 2023 Category: Neurology Authors: Yuto Uchida, Hirohito Kan, Gen Furukawa, Kengo Onda, Keita Sakurai, Koji Takada, Noriyuki Matsukawa and Kenichi Oishi Tags: Research Source Type: research
Characterization of choroid plexus in the preterm rabbit pup following subcutaneous administration of recombinant human IGF-1/IGFBP-3
Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates essential processes of vascular maturation and stabilization. Importantly, preterm birth is associated with reduced ... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 15, 2023 Category: Neurology Authors: Niklas Ortenl öf, Suvi Vallius, Helena Karlsson, Claes Ekström, Amanda Kristiansson, Bo Holmqvist, Olga Göransson, Magdaléna Vaváková, Martin Rydén, Galen Carey, Norman Barton, David Ley and Magnus Gram Tags: Research Source Type: research
Influence of head-over-body and body-over-head posture on craniospinal, vascular, and abdominal pressures in an acute ovine in-vivo model
Optimal shunt-based hydrocephalus treatments are heavily influenced by dynamic pressure behaviors between proximal and distal ends of shunt catheters. Posture-dependent craniospinal, arterial, venous, and abdo... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - August 2, 2023 Category: Neurology Authors: Anthony Podgor šak, Nina Eva Trimmel, Fabian Flürenbrock, Markus Florian Oertel, Margarete Arras, Miriam Weisskopf and Marianne Schmid Daners Tags: Research Source Type: research
Correction to: Estimates of the permeability of extra-cellular pathways through the astrocyte endfoot sheath
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 26, 2023 Category: Neurology Authors: Timo Koch, Vegard Vinje and Kent ‑André Mardal Tags: Correction Source Type: research
Sizes and shapes of perivascular spaces surrounding murine pial arteries
Flow of cerebrospinal fluid (CSF) through brain perivascular spaces (PVSs) is essential for the clearance of interstitial metabolic waste products whose accumulation and aggregation is a key mechanism of patho... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 17, 2023 Category: Neurology Authors: Nikola Raicevic, Jarod M. Forer, Antonio Ladr ón-de-Guevara, Ting Du, Maiken Nedergaard, Douglas H. Kelley and Kimberly Boster Tags: Research Source Type: research
Correction to: The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 14, 2023 Category: Neurology Authors: Ivana Lazarevic, Sasha Soldati, Josephine A. Mapunda, Henriette Rudolph, Maria Rosito, Alex Cardoso de Oliveira, Gaby Enzmann, Hideaki Nishihara, Hiroshi Ishikawa, Tobias Tenenbaum, Horst Schroten and Britta Engelhardt Tags: Correction Source Type: research
Plasma and cerebrospinal fluid concentrations of neurofilament light protein correlate in patients with idiopathic normal pressure hydrocephalus
Neurofilament light chain protein (NFL), a marker of neuronal axonal degeneration, is increased in cerebrospinal fluid (CSF) of patients with idiopathic normal pressure hydrocephalus (iNPH). Assays for analysi... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 6, 2023 Category: Neurology Authors: A. Jeppsson, Å. Sandelius, A. Zettergren, S. Kern, I. Skoog, K. Blennow, H. Zetterberg, C. Wikkelsø, P. Hellström and M. Tullberg Tags: Research Source Type: research
Spontaneously hypertensive rats can become hydrocephalic despite undisturbed secretion and drainage of cerebrospinal fluid
Hydrocephalus constitutes a complex neurological condition of heterogeneous origin characterized by excessive cerebrospinal fluid (CSF) accumulation within the brain ventricles. The condition may dangerously e... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 4, 2023 Category: Neurology Authors: Sara Diana Lolansen, Dagne Barbuskaite, Fenghui Ye, Jianming Xiang, Richard F. Keep and Nanna MacAulay Tags: Research Source Type: research
β1 integrin is essential for blood–brain barrier integrity under stable and vascular remodelling conditions; effects differ with age
Maintaining a tight blood –brain barrier (BBB) is an important prerequisite for the preservation of neurological health, though current evidence suggests it declines with age. While extracellular matrix-integri... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - July 3, 2023 Category: Neurology Authors: Sebok K. Halder, Violaine D. Delorme-Walker and Richard Milner Tags: Research Source Type: research
Unique features of the arterial blood –brain barrier
CNS vasculature differs from vascular networks of peripheral organs by its ability to tightly control selective material exchange across capillary barriers. Capillary permeability is mostly defined by unique c... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - June 27, 2023 Category: Neurology Authors: Batia Bell, Shira Anzi, Esther Sasson and Ayal Ben-Zvi Tags: Research Source Type: research
Nocturnal increase in cerebrospinal fluid secretion as a circadian regulator of intracranial pressure
It is crucial to maintain the intracranial pressure (ICP) within the physiological range to ensure proper brain function. The ICP may fluctuate during the light-dark phase cycle, complicating diagnosis and tre... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - June 23, 2023 Category: Neurology Authors: Annette Buur Steffensen, Beatriche Louise Edelbo, Dagne Barbuskaite, S øren Norge Andreassen, Markus Harboe Olsen, Kirsten Møller and Nanna MacAulay Tags: Research Source Type: research
Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries
This study aimed to develop a method to isolate brain capillaries from a single frozen... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - June 23, 2023 Category: Neurology Authors: Yudai Hamada, Seiryo Ogata, Takeshi Masuda, Shingo Ito and Sumio Ohtsuki Tags: Research Source Type: research
Correction to: Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells
(Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - June 19, 2023 Category: Neurology Authors: Simone S. E. Nielsen, Mikkel R. Holst, Kristine Langthaler, Sarah Christine Christensen, Elisabeth Helena Bruun, Birger Brodin and Morten S. Nielsen Tags: Correction Source Type: research
Ultrasound-mediated blood –brain barrier opening uncovers an intracerebral perivenous fluid network in persons with Alzheimer’s disease
Focused ultrasound (FUS)-mediated blood –brain barrier (BBB) opening is under investigation as a therapeutic modality for neurodegeneration, yet its effects in humans are incompletely understood. Here, we asses... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - June 16, 2023 Category: Neurology Authors: Rashi I. Mehta, Jeffrey S. Carpenter, Rupal I. Mehta, Marc W. Haut, Peng Wang, Manish Ranjan, Umer Najib, Pierre-Fran çois D’Haese and Ali R. Rezai Tags: Research Source Type: research
Reduced folate carrier 1 is present in retinal microvessels and crucial for the inner blood retinal barrier integrity
Reduced folate carrier 1 (RFC1; SLC19a1) is the main responsible transporter for the B9 family of vitamins named folates, which are essential for normal tissue growth and development. While folate deficiency r... (Source: Cerebrospinal Fluid Research)
Source: Cerebrospinal Fluid Research - June 16, 2023 Category: Neurology Authors: Gokce Gurler, Nevin Belder, Mustafa Caglar Beker, Melike Sever-Bahcekapili, Gokhan Uruk, Ertugrul Kilic and Muge Yemisci Tags: Research Source Type: research
