Epigenetic Hypothesis of the Role of Peptides in Aging
AbstractIn addition to transcription factors, epigenetic factors, which control the release of genetic information in each cell division, play an important role in the regulation of gene expression in the ontogenesis of multicellular eukaryotes. Many binding sites for transcription factors were derived from transposon sequences. Mobile elements are also important sources of noncoding RNA. Thus, transposons have an indirect effect on gene expression and genome methylation. In evolution transposons serve as important sources for the origin of new protein and proteins domains. A number of studies have determined that long non...
Source: Advances in Gerontology - July 1, 2018 Category: Geriatrics Source Type: research
Multimorbidity of Elderly Individuals in Urban and Rural Areas of the Nizhny Novgorod Region
AbstractThis paper compares the prevalence of pathological changes in different organs and systems among urban and rural residents of the following ages: elderly (60 –74 years for men and 55–74 years for women), senile (75–84 years), and advanced (85 years and older). The results of a continuous survey of all individuals of retirement age of one urban (7809 individuals) and two rural areas (14749 individuals) of the Nizhny Novgorod region were analyzed. Th e region is comparatively homogeneous in terms of the national composition of the population. In the city, the number of chronic pathologies of different organs an...
Source: Advances in Gerontology - July 1, 2018 Category: Geriatrics Source Type: research
Psychophysiological Monitoring of the State of the Organism in Elderly Female Teachers
AbstractThe purpose of the study is to psychophysiologically monitor elderly female teachers during the dynamics of the school year. The study was conducted with the participation of 30 female teachers aged 60 –61 at the beginning of the year (the background level) and after 5 and 9 months of teaching at the school. Five-minute ECG recording sections were studied with the Poly-Spectrum-Rhythm program (Neurosoft LLC). The parameters of external respiration function were studied with a Spirosoft-5000 devi ce. The psychoemotional state of the teachers during the school year was studied with SAM methodology (state of health,...
Source: Advances in Gerontology - July 1, 2018 Category: Geriatrics Source Type: research
Age-Associated Pathology and the Place of Geriatrics as a Medical Specialty (Reflections of a Clinician)
AbstractControversial issues of pathological processes associated with the elderly and senile age, along with several aspects of the organization of geriatric services that require discussion, are examined by a clinician based on his long-term experience in geriatrics. This paper is presented for public debate in this journal. (Source: Advances in Gerontology)
Source: Advances in Gerontology - July 1, 2018 Category: Geriatrics Source Type: research
Resources of Individual Psychological Security with Respect to the Employment Status of a Pensioner
AbstractTwo hundred pensioners aged 55 to 65 differing in employment status (working or retired) after retirement age and the character of that status (voluntary or involuntary) were surveyed. The content and the structure of the resources of the pensioners ’ personalities, the external determinants of the choice of their employment status, and the connection between the external determinants of the employment status and the resources of the psychological security of the pensioners’ personality were analyzed. These psychological resources consist o f resources of development and protection, which proves that the indivi...
Source: Advances in Gerontology - July 1, 2018 Category: Geriatrics Source Type: research
