Social Security of Aging: Problem Statement
AbstractThe author shows the need to consider aging in the context of social security. The humanizing stages of social security are shown, and it is demonstrated that its theoretical concepts tend to shift towards “human security,” which is developed within the frame of “enhanced security.” The main security object for elderly and senile persons is identified, i.e., the security of physical and mental health. The object of security is comprised of three components: safety of medical care, drug provisi on, and food security. The relevance of these issues to Russian practice is substantiated based on research materia...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
The Main Diseases and Syndromes Identified in Elderly and Senile Patients Hospitalized at Inpatient Clinics of Different Specialties
AbstractIn total, 661 patients have been examined in inpatient clinics; of these, 234 subjects are aged 60 to 102 years and 427 subjects are aged 18 to 59 years. The variants of pathologies that distinctly increase in prevalence with age are identified. First and foremost, these are pathologies of the locomotor system, gastrointestinal tract, and cardiovascular system. Conversely, cerebrovascular accidents (strokes) are prevalent in subjects under 60 years old, while the incidence of CAD and angina pectoris without the development of myocardial infarction in elderly and senile subjects insignificantly increases as compared...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Society for All Ages: Are There Any Prerequisites for its Formation in Russia?
AbstractThe problems of intergenerational interactions in the spheres of labor and leisure are studied in the context of the idea of a society for all ages. The results of measurement of intergenerational relations with sociological methods are presented. An attempt at measuring intergenerational relationships was made in the course of an expert survey conducted by the authors in 2016 within the framework of the project no. 16-02-00495 “Human Capital of the Senior Generation: Preservation and Use,” which was supported by the Russian Foundation for Humanities and the Russian Foundation for Basic Research. The trends in ...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Structure and Cytoarchitectonics of Lymphoid Tissue in Appendi сes of Elderly and Senile People
AbstractThe phenomenon of population aging has been observed in many countries in recent years due to the increase in human life expectancy. Therefore, studies of lymphoid tissue, which supports the immune processes in the human body, are now of particular importance. The lymphoid tissue of appendices from humans of age groups of 54 –81 years and 26–35 years was histologically studied, and the results were statistically treated. The lymphoid tissue belonging to senile age groups showed reductions and rearrangements with partial integrity of the modified lymphoid nodules. The majority of nodules were without lighter-sta...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Why and How Do We Age? A Single Answer to Two Questions
AbstractThe chemical properties of the compounds involved in metabolic processes, even the core ones, such as glycolysis and the Krebs cycle, are not confined to the properties utilized in enzymatic reactions; they include the ability to spontaneously form covalent bonds with other compounds, including macromolecule components. The effects of the gene that codes for an enzyme catalyzing the formation of a metabolite with such properties may be regarded as antagonistically pleiotropic. The effects implemented via the product of the reaction catalyzed by the enzyme coded for by the gene are required to maintain viability. As...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Protection of the Rights of Disabled People to Access Medicines
AbstractToday, disabled people remain one of the most vulnerable categories of the population in any region of the world. Access to safe, high-quality, and effective medicines as a key element of social well-being among disabled people remains a priority of the international agenda and national policy. The right of access to medicines among disabled people is not directly specified in any international document on the protection of the rights of the disabled, which certainly affects the availability of medicines for this population in various regions of the world. The article examines the main international legal documents...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
On the Correlation of Guarantees to Ensure the Labor Rights of the Elderly in Russia and Europe
AbstractMany lawyers, referring to the topic of guarantees for ensuring the labor rights of elderly people who receive a pension, begin their analysis from the provisions of Article 19 of the Russian Constitution on the prohibition of discrimination and Article 3 of the Labor Code of the Russian Federation on the prohibition of discrimination. The ILO Convention no. 111 on Discrimination in Employment and Occupation [8] also does not mention age as a discriminatory motive. At the same time, among the listed elements of Article 19 of the Constitution of the Russian Federation, there is no direct indication of age. Therefore...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Mast Cells of the Human Pineal Gland
AbstractThe goal of this work was to evaluate the efficiency of mast cell identification by different histochemical and immunohistochemical methods and to determine the features of their localization in the human pineal gland. Mast cells were found to be an essential component of the human pineal gland at any age. According to our data, the number of mast cells in the pineal gland increased with age. Mast cells were mostly located in the pineal stroma and did not tend to associate with concrements, cysts, or melanin accumulations. Mast cells in the pineal gland were predominantly non-degranulating, which indicated their in...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Melatonin and the Aging Process in Men in the European Part of the Arctic Zone of Russia
AbstractWe analyzed the concentrations of 6-sulfatoxymelatonin (6-SMT) in working-age men (aged 19 –69 years) living in the European part of the Arctic zone of Russia. The 6-SMT level in the studied group was similar to that in the control group of men living in Western Siberia. The 6-SMT level decreased with age and reached the minimal values at the age of 40–49 years. In the group aged 60– 69 years, there was a tendency to increase; however, the difference was not statistically significant (p> 0.05) as compared with men aged<29 years. We observed the effect of alcohol use on the 6-SMT level; it was lower in m...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Comparative Analysis of Indicators of Disability Due to Malignant New Growths in the Elderly
AbstractThe article analyzes the dynamics of indicators of primary, repeated, and general disability due to malignant new growths in the elderly in the city of Moscow during 2005 –2014 and determines the main medico-social characteristics of this contingent in comparison with indicators for the Central Federal District and Russian Federation. (Source: Advances in Gerontology)
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Effect of Personal History of Athletic Activity on the Clinical Course of Cardiovascular Diseases in Former Athletes
AbstractThis paper analyzes the prevalence and specifics of cardiac arrhythmias and conduction disorders in former athletes with diagnosed cardiovascular diseases as compared to the cohort of nonathletic cardiological patients with a comparable demographic profile and prevalence of hypertension and atherosclerosis. It is shown that the group of former athletes had a higher prevalence of hemodynamically significant pauses of asystole (RR 2.94,p = 0.044) and SA nodal blocks (RR 5.51,p = 0.02), and they required permanent pacemaker implantation more frequently (RR 5.14,p = 0.017). A higher level of athletic performance and ex...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
The Influence of Metformin on Age-Related Changes in the Number and Proliferation of Dermal Fibroblasts in Mice
AbstractThe goal of the work was to examine the effects of metformin on age-related changes in the number and proliferation of dermal fibroblasts in mice. The dermis was examined in 5-month-old mice that received drinking water with metformin at a concentration of 500 mg/L from the age of 2 months (within 90 days). Five-month-old mice that received drinking water without metformin were used as a control. Material from 2-month-old mice was also used in the work. We have counted the total number of dermal fibroblasts and a portion of fibroblasts with positive staining for the Ki-67 antigen. The results showed that there was ...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Study of Therapeutic Physical Exercise Impact on the Functional Status of Elderly Women
AbstractThis paper presents the results of a complex study of the therapeutic exercise impact on physical fitness indicators in elderly women with structural, metabolic, and functional changes. The study involved 12 women aged 61–66 years. All participants underwent physical examination, risk factor assessment, electrocardiography, and duplex scanning of extracranial vessels; the fasting glycemic level dynamics and PPG, as well as the fat indices, hemodynamics parameters, and functional test results were es timated. The results show that individual complexes of therapeutic exercises can significantly slow the paracmast...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Effect of Anthropo-Technogenic Load on Medico-Social Aspects of Primary Morbidity and Disability of Population
AbstractPopulation aging is a global social phenomenon that affects the most important health indicators of the population. The older generation is particularly vulnerable in the current conditions of urbanization and the associated environmental situation. The comprehension of indicators of disability and morbidity of the population, the study of the factors that determine the negative processes of health damage, with an accounting for the regional features of these processes, are necessary for the planning of preventive measures. Elderly disabled people make up 53.3% of the age structure of the primary disability of the ...
Source: Advances in Gerontology - December 31, 2018 Category: Geriatrics Source Type: research
Possible Approaches to Increase the Longevity of Experimental Animals
AbstractA statistically significant difference in the cumulative survival of Wistar rats born in different seasons has been shown: animals born in late November –early December had an average lifespan 24.8% longer, a minimum lifespan 14.3% longer, and a maximum lifespan 20.7% longer in comparison with animals born in April. Transplantation of thymus tissue into the immune privileged anterior chamber of the eye in animals born both in November and April ha s shown a geroprotective effect. (Source: Advances in Gerontology)
Source: Advances in Gerontology - October 1, 2018 Category: Geriatrics Source Type: research
