Compound heterozygous mutations in CFTR causing congenital bilateral absence of the vas deferens in a Chinese pedigree
ConclusionOur study revealed that compound heterozygous mutations ofCFTR are involved in CBAVD, expanding the knownCFTR gene mutation spectrum of CBAVD patients and providing more evidence that compound heterozygous mutations can cause familial CBAVD. (Source: Molecular Genetics & Genomic Medicine)
Source: Molecular Genetics & Genomic Medicine - January 18, 2024 Category: Genetics & Stem Cells Authors: Lingyi Li, Xiaowei Qu, Chenchen Cui, Ke Feng, Yanqing Xia, Feng Wan, Hengtao Ge, Yinghong Fang, Cuilian Zhang, Haibin Guo Tags: ORIGINAL ARTICLE Source Type: research

A micro-fabricated device (microICSI) improves porcine blastocyst development and procedural efficiency for both porcine intracytoplasmic sperm injection and human microinjection
ConclusionThe microICSI device demonstrated significant developmental and procedural benefits for porcine ICSI. A pilot study suggests human ICSI should benefit equally. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - January 18, 2024 Category: Reproduction Medicine Source Type: research

Endometriosis diagnosed by ultrasound is associated with lower live birth rates in women undergoing their first IVF/ICSI treatment
To study the cumulative live birth rate (CLBR) after the first In Vitro Fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI) treatment in women with or without deep infiltrating endometriosis (DIE) and/or endometrioma diagnosed by transvaginal ultrasonography (TVUS), using the International Deep Endometriosis Analysis (IDEA) group definitions. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 18, 2024 Category: Reproduction Medicine Authors: Sara Alson, Emir Henic, Ligita Jokubkiene, Povilas Sladkevicius Tags: Endometriosis Source Type: research

A micro-fabricated device (microICSI) improves porcine blastocyst development and procedural efficiency for both porcine intracytoplasmic sperm injection and human microinjection
ConclusionThe microICSI device demonstrated significant developmental and procedural benefits for porcine ICSI. A pilot study suggests human ICSI should benefit equally. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - January 18, 2024 Category: Reproduction Medicine Source Type: research

Sperm selection by zona adhesion improves assisted reproductive treatment outcomes
Discussion and conclusionThe application of solubilised zonae pellucidae in the sperm selection for ICSI benefits ART outcomes in couples with unexplained infertility. Moreover, sperm –zona selection significantly reduces the risk of miscarriages. (Source: Andrology)
Source: Andrology - January 16, 2024 Category: Urology & Nephrology Authors: Rumiana Ganeva, Dimitar Parvanov, Nina Vidolova, Maria Handzhiyska, Margarita Ruseva, Magdaleva Vasileva, Kristina Nikolova, Ivka Ivanova, Miray Shaban, Joanna Shabarkova, Rayna Hristova, Milena Miladinova, Georgi Stamenov Tags: ORIGINAL ARTICLE Source Type: research

Effect of prior cesarean delivery on the outcomes of intracytoplasmic sperm injection
CONCLUSION: The mode of prior delivery did not significantly impact pregnancy outcomes following frozen-thawed embryo transfer.PMID:38211968 | DOI:10.5653/cerm.2023.06163 (Source: Clinical and Experimental Reproductive Medicine)
Source: Clinical and Experimental Reproductive Medicine - January 11, 2024 Category: Reproduction Medicine Authors: Suzan Atteya Gewida Mohamed Salah Eldeen Abd Rabbo Mohammed Abd Elmoety El Samra Hesham Mahmoud Adel Abdel Moneim Source Type: research

Impact of congenital uterine anomalies on reproductive outcomes of IVF/ICSI-embryo transfer: a retrospective study
ConclusionsBoth canalization defects and unification defects were associated with lower fertility outcomes, including lower live birth rates, lower clinical pregnancy rates, and higher early miscarriage rates. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - January 11, 2024 Category: Research Source Type: research

A Successful Live Birth From a Vitrified Oocyte for Fertility Preservation of a Patient With Borderline Ovarian Tumor Undergoing Bilateral Ovarian Surgery: A Case Report
This article reports the live birth of a healthy newborn using vitrified-warmed oocytes from fertility preservation before ovarian surgery. The patient in our case underwent two cycles of controlled ovarian stimulation before laparoscopic bilateral ovarian cystectomy for endometriosis, and a total of 23 mature oocytes were vitrified. After surgery, her pathologic reports revealed a serous borderline tumor and endometrioma. Fifteen months after her second surgery of laparoscopic right salpingo-oophorectomy and left ovarian cystectomy owing to recurrence, she had been married by then, and three of the frozen oocytes were tha...
Source: J Korean Med Sci - January 9, 2024 Category: General Medicine Authors: Yae Ji Choi Yeon Hee Hong Haerin Paik Seul Ki Kim Jung Ryeol Lee Chang Suk Suh Source Type: research

A Successful Live Birth From a Vitrified Oocyte for Fertility Preservation of a Patient With Borderline Ovarian Tumor Undergoing Bilateral Ovarian Surgery: A Case Report
This article reports the live birth of a healthy newborn using vitrified-warmed oocytes from fertility preservation before ovarian surgery. The patient in our case underwent two cycles of controlled ovarian stimulation before laparoscopic bilateral ovarian cystectomy for endometriosis, and a total of 23 mature oocytes were vitrified. After surgery, her pathologic reports revealed a serous borderline tumor and endometrioma. Fifteen months after her second surgery of laparoscopic right salpingo-oophorectomy and left ovarian cystectomy owing to recurrence, she had been married by then, and three of the frozen oocytes were tha...
Source: Journal of Korean Medical Science - January 9, 2024 Category: Biomedical Science Authors: Yae Ji Choi Yeon Hee Hong Haerin Paik Seul Ki Kim Jung Ryeol Lee Chang Suk Suh Source Type: research

A Successful Live Birth From a Vitrified Oocyte for Fertility Preservation of a Patient With Borderline Ovarian Tumor Undergoing Bilateral Ovarian Surgery: A Case Report
This article reports the live birth of a healthy newborn using vitrified-warmed oocytes from fertility preservation before ovarian surgery. The patient in our case underwent two cycles of controlled ovarian stimulation before laparoscopic bilateral ovarian cystectomy for endometriosis, and a total of 23 mature oocytes were vitrified. After surgery, her pathologic reports revealed a serous borderline tumor and endometrioma. Fifteen months after her second surgery of laparoscopic right salpingo-oophorectomy and left ovarian cystectomy owing to recurrence, she had been married by then, and three of the frozen oocytes were tha...
Source: J Korean Med Sci - January 9, 2024 Category: General Medicine Authors: Yae Ji Choi Yeon Hee Hong Haerin Paik Seul Ki Kim Jung Ryeol Lee Chang Suk Suh Source Type: research

A Successful Live Birth From a Vitrified Oocyte for Fertility Preservation of a Patient With Borderline Ovarian Tumor Undergoing Bilateral Ovarian Surgery: A Case Report
This article reports the live birth of a healthy newborn using vitrified-warmed oocytes from fertility preservation before ovarian surgery. The patient in our case underwent two cycles of controlled ovarian stimulation before laparoscopic bilateral ovarian cystectomy for endometriosis, and a total of 23 mature oocytes were vitrified. After surgery, her pathologic reports revealed a serous borderline tumor and endometrioma. Fifteen months after her second surgery of laparoscopic right salpingo-oophorectomy and left ovarian cystectomy owing to recurrence, she had been married by then, and three of the frozen oocytes were tha...
Source: Journal of Korean Medical Science - January 9, 2024 Category: Biomedical Science Authors: Yae Ji Choi Yeon Hee Hong Haerin Paik Seul Ki Kim Jung Ryeol Lee Chang Suk Suh Source Type: research

Advances in microfluidic technology for sperm screening and in vitro fertilization
Anal Bioanal Chem. 2024 Jan 8. doi: 10.1007/s00216-023-05120-9. Online ahead of print.ABSTRACTAbout 18% of reproductive-age adults worldwide are affected by infertility. In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are widely used assisted reproductive technologies (ARTs) aimed at improving clinical outcomes. Efficient and noninvasive selection and isolation of highly motile sperm with intact DNA are essential for the success of IVF and ICSI and can potentially impact the therapeutic efficacy and the health of the offspring. Compared to traditional methods, microfluidic technology offers signifi...
Source: Analytical and Bioanalytical Chemistry - January 8, 2024 Category: Chemistry Authors: Jingtong Ma Qianlin Xie Yusongjia Zhang Qirui Xiao Xiaoyu Liu Chong Qiao Ye Tian Source Type: research

Advances in microfluidic technology for sperm screening and in vitro fertilization
Anal Bioanal Chem. 2024 Jan 8. doi: 10.1007/s00216-023-05120-9. Online ahead of print.ABSTRACTAbout 18% of reproductive-age adults worldwide are affected by infertility. In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are widely used assisted reproductive technologies (ARTs) aimed at improving clinical outcomes. Efficient and noninvasive selection and isolation of highly motile sperm with intact DNA are essential for the success of IVF and ICSI and can potentially impact the therapeutic efficacy and the health of the offspring. Compared to traditional methods, microfluidic technology offers signifi...
Source: Analytical and Bioanalytical Chemistry - January 8, 2024 Category: Chemistry Authors: Jingtong Ma Qianlin Xie Yusongjia Zhang Qirui Xiao Xiaoyu Liu Chong Qiao Ye Tian Source Type: research

Impact of COVID-19 disease on the male factor in reproductive medicine - how-to advise couples undergoing IVF/ICSI
CONCLUSIONS: The findings of this narrative review suggest that SARS-CoV-2 may harm sperm quality in the acute phase.IMPLICATIONS: A recovery time of at least 3months regarding assisted reproductive therapy could be reasonable.PMID:38185121 | DOI:10.1071/RD23205 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - January 7, 2024 Category: Reproduction Medicine Authors: Julia Stark Stefan P Kuster Vera Hungerb ühler Source Type: research

Impact of COVID-19 disease on the male factor in reproductive medicine - how-to advise couples undergoing IVF/ICSI
CONCLUSIONS: The findings of this narrative review suggest that SARS-CoV-2 may harm sperm quality in the acute phase.IMPLICATIONS: A recovery time of at least 3months regarding assisted reproductive therapy could be reasonable.PMID:38185121 | DOI:10.1071/RD23205 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - January 7, 2024 Category: Reproduction Medicine Authors: Julia Stark Stefan P Kuster Vera Hungerb ühler Source Type: research