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UCLA research could be step toward lab-grown eggs and sperm to treat infertility
A new study on how and when the precursors to eggs and sperm are formed during development could help pave the way for generating egg and sperm cells in the lab to treat infertility.The study, published in the journal Cell Reports, describes the way in which human stem cells evolve into germ cells, the precursors for egg and sperm cells.“Right now, if your body doesn’t make germ cells then there’s no option for having a child that’s biologically related to you,” said Amander Clark, the study’s lead author, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem...
Source: UCLA Newsroom: Health Sciences - February 6, 2020 Category: Universities & Medical Training Source Type: news
Frozen Embryo Transfer Tied to Cancer Risk in Kids
There wasn't an increased cancer risk among children born to parents who used other types of assisted reproductive technology such as fertility drugs, IVF or intracytoplasmic sperm injection. (Source: WebMD Health)
Source: WebMD Health - December 12, 2019 Category: Consumer Health News Source Type: news
IVF clinics are 'embezzling' £42million from desperate patients by charging for extra treatments
Professor Chris Barratt, of of Dundee University, said around half of couples are being offered ICSI, an additional IVF technique designed to help men with poor sperm. But not all men need it. (Source: the Mail online | Health)
Source: the Mail online | Health - December 5, 2019 Category: Consumer Health News Source Type: news
Featured Review: Interventions for unexplained infertility
Couples are classified as having unexplained infertility when they have tried to conceive for at least one year and no abnormality in semen analysis, ovulation, or tubal patency has been identified. Treatment options for unexplained infertility include expectant management, ovarian stimulation (OS), intrauterine insemination (IUI), OS-IUI, and in vitro fertilisation (IVF) with or without intracytoplasmic sperm injection (ICSI). Cochrane authors conductednetwork meta-analysis on interventions for unexplained infertility.Cochrane Gynecology and Fertility sat down with Dr Rui Wang, the lead author of the study, who answered t...
Source: Cochrane News and Events - September 27, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news
Meet the families who say we're glorious proof you don't need IVF
Laura underwent two NHS-funded attempts at IVF, using a technique called intracytoplasmic sperm injection (ICSI), where a single sperm was injected into one of Laura's eggs. (Source: the Mail online | Health)
Source: the Mail online | Health - August 27, 2019 Category: Consumer Health News Source Type: news
Podcast: Assisted reproductive technology: an overview of Cochrane Reviews
Cochrane Overviews bring together the findings from multiple reviews and one of the largest, first published in September 2013, was updated and republished in May 2018. Cindy Farquhar, from the Department of Obstetrics and Gynaecology at the University of Auckland in New Zealand describes this enormous volume of evidence for assisted reproduction." Infertility is defined as failure to conceive after one year of trying. Up to one in six couples will experience this at some point in their lives and many will seek fertility treatment in the form of assisted reproduction. When they do so, they will hope that they are gett...
Source: Cochrane News and Events - August 7, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news
Report: Google Android lets apps track you regardless of permissions
(Natural News) According to a recent study, Google’s Android operating system is allowing more than 1,300 apps to bypass system permissions controlling access to user data to track users without their knowledge. (Article by Lucas Nolan republished from Breitbart.com) ZDNet reports that a recent study by the International Computer Science Institute (ICSI) claims that as many... (Source: NaturalNews.com)
Source: NaturalNews.com - July 9, 2019 Category: Consumer Health News Source Type: news
European pregnancy rates from IVF and ICSI 'appear to have reached a peak'
(European Society of Human Reproduction and Embryology) The latest annual data collected by ESHRE from European national registries (for 2016) show another rise in the cumulative use of IVF in the treatment of infertility, although success rates after IVF or ICSI appear to have reached a peak, with pregnancy rates per started treatment calculated at 27.1% after IVF and 24.3% after ICSI. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 25, 2019 Category: International Medicine & Public Health Source Type: news
Large cohort study confirms small added obstetric risk from transfer of longer developed embryos
(European Society of Human Reproduction and Embryology) The transfer of embryos cultured for five or six days (instead of two or three) after fertilisation in IVF and ICSI has become routine in many fertility clinics. Many (but not all) studies show that transferring these longer and better developed embryos - known as blastocysts - will increase the chance of pregnancy and live birth. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 24, 2019 Category: International Medicine & Public Health Source Type: news
IVF add-on procedure that costs an extra £1,000 is actually LESS effective for healthy couples
Researchers from the Royal Women's Hospital in Melbourne and Melbourne IVF analysed the results of more than 3,300 IVF cycles and found just 13.6 per cent of ICSI procedures led to births. (Source: the Mail online | Health)
Source: the Mail online | Health - June 11, 2019 Category: Consumer Health News Source Type: news
Older fathers a risk to health of partners and unborn children
Men should be counselled on risks linked to paternal age Related items fromOnMedica Fewer than ever women smoke at point of birth Obese couples take longer to achieve pregnancy Patients face postcode lottery for IVF, new data shows Doctors and midwives welcome clear alcohol advice Doubled use of ICSI did not improve outcomes in US (Source: OnMedica Latest News)
Source: OnMedica Latest News - May 13, 2019 Category: UK Health Source Type: news
No Increased Risk for Cancer for ART - Conceived Children
Slightly but not significantly increased risks seen in children conceived by ICSI or cryopreservation (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 5, 2019 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pediatrics, Journal, Source Type: news
Why So Many Women Travel to Denmark for Fertility Treatments
Holly Ryan knows the biological father of her children has two sisters, is a Coldplay fan, and doesn’t like eating chicken in pasta dishes. She knows his mother is a nurse and his father is a policeman, and that his aunt has green eyes and curly hair. She even has a photo of him as a child, and an audio recording of his voice. But Ryan, 41, doesn’t know his name and has never met him. More than six years ago, she decided she wanted to start a family. “Once you commit to trying to get pregnant, it becomes a kind of obsession,” says Ryan, the director of a talent agency for TV directors, producers and...
Source: TIME: Health - January 3, 2019 Category: Consumer Health News Authors: Naina Bajekal/Copenhagen Tags: Uncategorized Denmark Source Type: news
What We're Doing Right And What Can Be Better About IVF
The same vision and imagination that resulted in the invention of IVF, embryo freezing, ICSI, oocyte vitrification, and preimplantation genetics will, with a bit of innovation capital and seed funding, evolve the IVF industry into one of the most important branches of medicine in the 21st-century. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - October 7, 2018 Category: Pharmaceuticals Authors: David Sable, Contributor Source Type: news
Genetic Testing Doesn't Boost Live-Birth Rates in Older Women Planning ICSI Genetic Testing Doesn't Boost Live-Birth Rates in Older Women Planning ICSI
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 20, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news
ICSI treatment linked to increased prostate cancer risk
Men who undergo ICSI (intracytoplasmic sperm injection) are at greater risk of developing prostate cancer, according to a large study presented during the European Society of Human Reproduction and Embryology annual meeting.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - July 4, 2018 Category: Endocrinology Source Type: news
Sub-fertility in men treated with ICSI associated with an increased risk of prostate cancer
(European Society of Human Reproduction and Embryology) Subfertile men who have received fertility treatment with the microinjection technique of ICSI (intracytoplasmic sperm injection) have been found at a significantly greater risk of prostrate cancer, according to an analysis of three comprehensive nationwide registries in Sweden. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 3, 2018 Category: Cancer & Oncology Source Type: news
Thousands of mobile apps for children might be violating their privacy
(IMDEA Networks Institute) Thousands of the most popular apps and games available, mostly free of charge, in the Google Play Store, make potentially illegal tracking of children's use habits, according to a large-scale international study co-authored by Narseo Vallina-Rodriguez, a researcher at the IMDEA Networks Institute in Madrid and ICSI, the International Computer Science Institute at the University of California, Berkeley (USA). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 24, 2018 Category: International Medicine & Public Health Source Type: news
FDA clears DxNow ’ s sperm separation device
Medical device developer DxNow said today it won FDA 510(k) clearance for its ZyMōt ICSI and ZyMōt multi sperm separation devices designed for use in assisted reproductive technology procedures. The newly cleared devices from the Gaithersburg, Md.-based company are designed for preparing motile sperm from semen for use in the treatment of infertile couples by intracytoplasmic sperm injection, intrauterine insemination and in vitro fertilization procedures. “We are excited to announce the achievement of this significant milestone in our company’s evolution. This announcement follows CE certification and the in...
Source: Mass Device - March 15, 2018 Category: Medical Devices Authors: Fink Densford Tags: 510(k) Food & Drug Administration (FDA) Regulatory/Compliance dxnow Source Type: news
DxNow, Inc. Receives FDA 510(k) Clearance for ZyMand#333;t(TM) ICSI and ZyMand#333;t(TM) Multi Sperm Separation Devices
Novel Devices Advance Fertility Treatment for Millions of Couples Striving to Conceive GAITHERSBURG, Md., March 15, 2018 -- (Healthcare Sales & Marketing Network) -- DxNow, Inc., a privately held medical device company, announces receipt of FDA 510(k) ... Devices, FDA DxNow, ZyMōt, assisted reproductive technology (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 15, 2018 Category: Pharmaceuticals Source Type: news
Spontaneous Preterm Birth Rates Higher With IVF/ICSI Spontaneous Preterm Birth Rates Higher With IVF/ICSI
Reuters Health Information (Source: Medscape ObGyn and Womens Health Headlines)
Source: Medscape ObGyn and Womens Health Headlines - December 5, 2017 Category: OBGYN Tags: Ob/Gyn & Women ' s Health News Source Type: news
In vitro fertilization linked with increased risk of congenital heart defects
(Wiley) A new analysis of published studies found a 45 percent increased risk of congenital heart defects in newborns when women become pregnant via in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) than through spontaneous conception. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 22, 2017 Category: International Medicine & Public Health Source Type: news
Fertile offspring from sterile sex chromosome trisomic mice
Having the correct number of chromosomes is vital for normal development and health. Sex chromosome trisomy affects 0.1% of the human population and is associated with infertility. We show that during reprogramming to induced pluripotent stem cells (iPSCs), fibroblasts from sterile trisomic XXY and XYY mice lose the extra sex chromosome through a phenomenon we term trisomy-biased chromosome loss (TCL). Resulting euploid XY iPSCs can be differentiated into the male germ cell lineage and functional sperm that can be used in intracytoplasmic sperm injection to produce chromosomally normal, fertile offspring. Sex chromosome lo...
Source: ScienceNOW - August 31, 2017 Category: Science Authors: Hirota, T., Ohta, H., Powell, B. E., Mahadevaiah, S. K., Ojarikre, O. A., Saitou, M., Turner, J. M. A. Tags: Genetics reports Source Type: news
Spain now sets the pace of assisted reproduction in Europe with more than 100,000 treatments a year
(European Society of Human Reproduction and Embryology) Spain is Europe's most active country in assisted reproduction. ESHRE has collected the national registry data of ART cycles performed in Europe since 1997 and for its latest report (for 2014) found that a record 109,275 treatment cycles were performed in Spain, which now sets the pace of European ART ahead of Russia (94.985 cycles) and former front runner France (90,434). The cycles monitored by ESHRE include treatments with IVF, ICSI, egg donation and intrauterine insemination (IUI). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 4, 2017 Category: International Medicine & Public Health Source Type: news
The ABCs Of Fertility Treatments That You Need To Know
For BRIDES, by Kelsey Butler. Infertility: It’s a topic that is definitely difficult to talk about, but extremely important to discuss as you think about planning for a family. In fact, with about one in eight couples having trouble getting or staying pregnant, it’s likely that you or someone you know is going through this tough battle. To make it even harder, there is an overwhelming amount of information out there (what the heck do some of these acronyms even stand for?). We’re breaking down some important guidelines on when it’s time to head to the doctor and the key fertility treatment terms yo...
Source: Healthy Living - The Huffington Post - June 9, 2017 Category: Consumer Health News Source Type: news
What a pain! – Lisa ’ s story
The post What a pain! – Lisa’s story appeared first on Hysterectomy Association. I knew I had endometriosis as it had a laparoscopy that identified this in my mid thirties as part of infertility investigations. I tried ICSI once after that and paid privately but we were unsuccessful in having a baby. We carried on ‘leaving it up to nature’ for many years after that but nothing happened. At the age of forty three we decided that we wouldn’t actively pursue my getting pregnant any more and put the idea to bed – my husband has a 17 yr old daughter from a previous marriage and she lives...
Source: The Hysterectomy Association - February 25, 2017 Category: OBGYN Authors: Linda Tags: Your Stories endometriosis Source Type: news
Expensive IVF add-ons 'not evidence based'
Conclusion The researchers rightly say "people seeking fertility treatment need good-quality evidence to make informed choices". As the system currently stands, people seek treatment from a variety of private UK fertility clinics. In their desire for a baby, many couples are in a vulnerable situation and rely heavily on the guidance of health professionals. But clinics may offer treatments that aren't sufficiently backed by the evidence. The researchers highlight several problems. The standard first-step recommendation is for people to ask their GP for advice. But GPs are unlikely to have the specialis...
Source: NHS News Feed - November 28, 2016 Category: Consumer Health News Tags: Pregnancy/child QA articles Source Type: news
Online calculator that tries to predict IVF success released
Conclusion This study aimed to develop a model that could predict the chances of a live birth over multiple cycles of in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI). The model used a large quantity of data taken from reliable UK medical records belonging to couples who had previously undergone IVF or ICSI. The model also benefits from being able to account for a large number of personal and treatment characteristics. The researchers developed two models for couples in both the pre-treatment and post-treatment phase of treatment cycles. They hope this online tool will serve as an aid for couples ...
Source: NHS News Feed - November 18, 2016 Category: Consumer Health News Tags: Pregnancy/child Source Type: news
Medical News Today: Men conceived through IVF may inherit father's fertility problems
The first ever analysis of men conceived though intracytoplasmic sperm injection reveals the procedure may be linked to poorer sperm count and quality. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 6, 2016 Category: Consumer Health News Tags: Fertility Source Type: news
Men conceived by IVF 'may inherit sperm problems'
Conclusion This small cross-sectional study aimed to assess the semen quality of young men who were conceived by ICSI. The study found that when compared with men conceived naturally, men conceived by ICSI had a lower average sperm concentration, total sperm count, and total motile sperm count. This effect remained after the team adjusted for potential confounders. This finding supports concerns that the infertility of a father could be passed on to male offspring, but does not prove it. The study does not rule in or out the possibility of the difference being a result of the ICSI procedure itself or an u...
Source: NHS News Feed - October 6, 2016 Category: Consumer Health News Tags: Pregnancy/child Medical practice Source Type: news
Tests on men born using IVF find they also suffer from low sperm counts
Tests on the first group of men to have been born using the ICSI technique have now shown that they too suffer from low sperm counts and poor-moving sperm. (Source: the Mail online | Health)
Source: the Mail online | Health - October 6, 2016 Category: Consumer Health News Source Type: news
Boys conceived through IVF technique have lower than average fertility
Tests on young men conceived via intra-cytoplasmic sperm injection show that they have lower sperm quantity and quality that those conceived naturallyBoys conceived using an assisted reproductive technique in which sperm is injected directly into the egg have lower fertility than average, scientists have found.The results come from the first generation of boys conceived using a technique called intra-cytoplasmic sperm injection (ICSI), who are just reaching adulthood, and show that the young men have lower sperm quantity and quality than those conceived spontaneously.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 6, 2016 Category: Science Authors: Hannah Devlin Science correspondent Tags: Reproduction IVF Science Biology Fertility problems Health Source Type: news
Cochrane Priority Reviews List: September 2016 Update
Cochrane-wide prioritization remains an important project and has been included in theStrategy to 2020 Targets for 2016. Almost 120 priority reviews or updates have been published since the project began.The September 2016 revision of the Cochrane Priority Reviews List includes new titles from the Cochrane Acute Respiratory Infections, Airways, Injuries, Gynaecology and Fertility, Hepato-Biliary, Oral Health, Skin, Tobacco Addiction, and Vascular Groups.The following titles on the list are open to new authors:Drugs for preventing postoperative nausea and vomitingEffectiveness and safety of skin testing before providing pen...
Source: Cochrane News and Events - September 8, 2016 Category: Information Technology Authors: mumoquit at cochrane.org Source Type: news
How Does Thyroid Autoimmunity Affect IVF Outcomes? How Does Thyroid Autoimmunity Affect IVF Outcomes?
Dr Peter Kovacs reviews a meta-analysis that evaluated the impact of isolated thyroid autoimmunity on IVF/ICSI outcome.Medscape Ob/Gyn (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 31, 2016 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Viewpoint Source Type: news
Rocky Mountain Fertility Center Joins US Fertility Network, Now...
Top Denver fertility clinic, Rocky Mountain Fertility Center, has joined the US Fertility Network and is offering 15% off treatment. Treatment is offered by an Award Winning, Board Certified Colorado...(PRWeb July 20, 2016)Read the full story at http://www.prweb.com/releases/coloradofertilitydoctor/ivf-icsi/prweb13564885.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 20, 2016 Category: Pharmaceuticals Source Type: news
Couples charged £1,000 extra for ICSI treatment that CUTS their chance of baby
Doctors are increasingly pushing a lab technique called ICSI, where a single sperm is injected directly into the egg. Critics say the scientific method should be a 'last resort'. (Source: the Mail online | Health)
Source: the Mail online | Health - July 10, 2016 Category: Consumer Health News Source Type: news
Most popular form of IVF given to thousands of couples is 'ineffective'
Professor Hans Evers, of Maastrich University, said intracytoplasmic sperm injection (ICSI) is expensive and is being inappropriately given to couples who won't benefit from it. (Source: the Mail online | Health)
Source: the Mail online | Health - May 23, 2016 Category: Consumer Health News Source Type: news
World report on fertility treatments reveals high use of intracytoplasmic sperm injection
Experts have attacked the rising use of intracytoplasmic sperm injection (ICSI) for the treatment of infertility, following publication of the latest world report on assisted reproductive technologies. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 21, 2016 Category: Science Source Type: news
World report on fertility treatments reveals high use of intracytoplasmic sperm injection
(European Society of Human Reproduction and Embryology) The editor-in-chief of one of the world's leading reproductive medicine journals, Human Reproduction, has attacked the rising use of intracytoplasmic sperm injection (ICSI) for the treatment of infertility, following publication of the latest world report on assisted reproductive technologies; he brands it as 'ineffective and costly care.' (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 20, 2016 Category: Global & Universal Source Type: news
Trouble Having a Baby? It Might Be Male Infertility
Infertility is often viewed as a woman's problem but when a couple has trouble conceiving, there's a good chance it's related to male factors -- in fact, that's the case 40-50 percent of the time. That's why the male partner should be part of any couple's fertility assessment. Not only is male infertility more common than most people realize, male factors are the sole reason for a couple's inability to have a baby 15 percent to 25 percent of the time. While some reasons for male infertility are well understood, at least 50 percent of problems are due to unknown factors. Male infertility can occur when men have a less t...
Source: Healthy Living - The Huffington Post - May 17, 2016 Category: Consumer Health News Source Type: news
Infertility treatments 'not linked' to developmental delays
ConclusionThis prospective cohort study aimed to assess whether use of and type of infertility treatment was associated with a child's development up to the age of 36 months. The study found no convincing evidence that infertility treatment had any impact on a child's development, which will come as a relief to parents who have undertaken treatment. However, while this type of observational study is good for looking at links between an exposure and an outcome over a period of time, it is not able to prove direct cause and effect and say for certain whether there is any link between two factors. For example, various socioec...
Source: NHS News Feed - January 5, 2016 Category: Consumer Health News Tags: Medical practice Pregnancy/child Source Type: news
Does red meat affect male fertility?
ConclusionThis study of a cohort of men attending a fertility clinic for help to conceive found fertilisation rates in the laboratory during IVF were less successful if men reported a diet high in processed meat, and more successful if they ate more chicken. Importantly, the effect of overall meat intake was not related to fertility success, which is the chance of becoming pregnant after the treatment cycles, or having a live birth. It was also not clear whether the variation in fertility rate influenced how many cycles of IVF were needed, or how long the couple needed medical assistance, before they became pregnant or had...
Source: NHS News Feed - August 11, 2015 Category: Consumer Health News Tags: Food/diet Pregnancy/child Source Type: news
Rate of ectopic pregnancy following IVF has almost halved in past 12 years
The risk of ectopic pregnancy following fertility treatment with assisted reproduction (ART) is small but significantly higher than found in natural conceptions. Now, a nationwide population-based analysis of all ART pregnancies achieved in the UK between 2000 and 2012 has found that the rate of ectopic pregnancy following IVF and ICSI progressively decreased throughout these 12 years, almost halving from an overall rate of 20 to 12 cases per thousand. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 16, 2015 Category: Science Source Type: news
Rate of ectopic pregnancy following IVF has almost halved in past 12 years
(European Society of Human Reproduction and Embryology) The risk of ectopic pregnancy following fertility treatment with assisted reproduction (ART) is small but significantly higher than found in natural conceptions. Now, a nationwide population-based analysis of all ART pregnancies achieved in the UK between 2000 and 2012 has found that the rate of ectopic pregnancy following IVF and ICSI progressively decreased throughout these 12 years, almost halving from an overall rate of 20 to 12 cases per thousand. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 16, 2015 Category: Global & Universal Source Type: news
Why are so many British women travelling abroad for fertility treatment?
With claims of better success rates, pioneering treatments and cheaper IVF, foreign clinics are cleaning up. So are 'fertility tourists' getting a better deal? (Source: Telegraph Health)
Source: Telegraph Health - March 28, 2015 Category: Consumer Health News Tags: egg freezing embryoscope stella icsi fertility tourism advances in ivf spanish fertility clinic era uk ivf success rates stella magazine eshre Source Type: news
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include chlorhexidine baths in the ICU, dangers of too much sitting, intracytoplasmic sperm injection, and stem-cell therapy for MS. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - January 25, 2015 Category: Endocrinology Source Type: news
Injecting Sperm More Popular but Does Not Improve OutcomesInjecting Sperm More Popular but Does Not Improve Outcomes
Intracytoplasmic sperm injection, a relatively new technique that by 2012 had soared to represent 76.2% of fresh in vitro fertilization cycles, was not associated with improved reproductive outcomes. Medscape Medical News (Source: Medscape ObGyn and Womens Health Headlines)
Source: Medscape ObGyn and Womens Health Headlines - January 21, 2015 Category: OBGYN Tags: Ob/Gyn & Women ' s Health News Source Type: news
Nordic IVF outcomes improving - is the same true for the UK?
Conclusion This study found an improvement in health outcomes around the time of birth for babies conceived using artificial reproductive technology (IVF, ICSI and frozen embryo transfer) over the last 20 years in four Nordic countries (Norway, Sweden, Denmark and Finland). The study sample was large and the methods robust. This means we can be relatively confident these results paint an accurate picture of what is going on in these countries. But two questions remain: are similar results found in the UK, and what is behind the improvement? On the first question, it is difficult to say without ha...
Source: NHS News Feed - January 21, 2015 Category: Consumer Health News Tags: Medical practice Pregnancy/child Source Type: news
Could 'DNA editing' lead to designer babies?
Conclusion This laboratory research using sperm and egg cells from mice demonstrates the use of a system to produce targeted alterations in the DNA – a process the media like to call “genetic editing”. The editing happened just before the genetic material of the egg and sperm cell fuse together. The system makes use of an enzyme (Cas9) capable of cutting bonds within DNA, and a “guide” molecule targeting it to the correct genetic location. So far, the techniques have only been tested in animals, and for “editing out” a small number of genes. However, though this is very earl...
Source: NHS News Feed - January 19, 2015 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Source Type: news
Freeze-Drying of Mammalian Sperm
Long-term preservation of mammalian sperm at suprazero temperatures is desired to save storage and space costs as well as to facilitate transport of preserved samples. This can be accomplished by the freeze-drying of sperm samples. Although freeze-drying results in immotile and membrane-compromised sperm, intracytoplasmic sperm injection (ICSI) can be used to introduce such an immotile sperm into an oocyte and thus start the fertilization process. So far, it has been shown that improved freeze-drying protocols preserve chromosomal integrity and oocyte-activating factor(s) at 4 °C for several years and at ambient temper...
Source: Springer protocols feed by Biotechnology - December 2, 2014 Category: Biotechnology Source Type: news