Impact of COVID-19 disease on the male factor in reproductive medicine - how-to advise couples undergoing IVF/ICSI
CONCLUSIONS: The findings of this narrative review suggest that SARS-CoV-2 may harm sperm quality in the acute phase.IMPLICATIONS: A recovery time of at least 3months regarding assisted reproductive therapy could be reasonable.PMID:38185121 | DOI:10.1071/RD23205 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - January 7, 2024 Category: Reproduction Medicine Authors: Julia Stark Stefan P Kuster Vera Hungerb ühler Source Type: research

Optimizing non-invasive preimplantation genetic testing: investigating culture conditions, sample collection, and IVF treatment for improved non-invasive PGT-A results
ConclusionWe have shown a higher concordance rate when SCM was collected on day 6 and the embryos were rinsed in a sequential manner. Comparable results of niPGT-A when oocytes were fertilized by conventional insemination or ICSI. These optimization steps are important prior to commencement of a randomized trial in niPGT-A. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - January 6, 2024 Category: Reproduction Medicine Source Type: research

“Comparison of Outcomes Between Intracytoplasmic Sperm Injection and In Vitro Fertilization with Pre-implantation Genetic Testing for Aneuploidy, Analysis of SART CORS Data”.
To evaluate whether insemination via intracytoplasmic sperm injection provides any benefit over in vitro fertilization for non-male factor infertility with respect to pre-implantation genetic testing results and pregnancy outcome. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 5, 2024 Category: Reproduction Medicine Authors: Jessica Tozour, Alicia Arnott, Meredith Akerman, Linda Sung, Anthony Vintzileos, Rani Fritz Tags: Assisted reproduction Source Type: research

Comparison of outcomes between intracytoplasmic sperm injection and in  vitro fertilization inseminations with preimplantation genetic testing for aneuploidy, analysis of Society for Assisted Reproductive Technology Clinic Outcome Reporting System data
To evaluate whether insemination via intracytoplasmic sperm injection (ICSI) provides any benefit over in  vitro fertilization (IVF) insemination for nonmale factor infertility with respect to preimplantation genetic testing (PGT) results and pregnancy outcome. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 5, 2024 Category: Reproduction Medicine Authors: Jessica N. Tozour, Alicia Arnott, Meredith Akerman, Linda Sung, Anthony Vintzileos, Rani Fritz Tags: Assisted reproduction Source Type: research

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)
CONCLUSIONS: We did not find that tailoring the FSH dose in any particular ORT population (low, normal, high ORT) affected live birth/ongoing pregnancy rates, but we could not rule out differences, due to sample size limitations. Low-certainty evidence suggests that it is unclear if ORT-based individualisation leads to an increase in live birth/ongoing pregnancy rates compared to a policy of giving all women 150 IU. The confidence interval is consistent with an increase of up to around six percentage points with ORT-based dosing (e.g. from 25% to 31%) or a very small decrease (< 1%). A difference of this magnitude could...
Source: Cochrane Database of Systematic Reviews - January 4, 2024 Category: General Medicine Authors: Olina Ngwenya Sarah F Lensen Andy Vail Ben Willem J Mol Frank J Broekmans Jack Wilkinson Source Type: research

Comparative study of intracytoplasmic sperm injection using the traditional holding and the oocyte-holding pipette without aspiration
Zygote. 2024 Jan 4:1-6. doi: 10.1017/S0967199423000618. Online ahead of print.ABSTRACTDespite the high level of standardization of the intracytoplasmic sperm injection (ICSI) technique, there are some aspects that deserve special attention and should still be improved. The major drawback of the technique is its invasiveness, as during cytoplasmic aspiration different structures of the oocyte may be lost or damaged. This is partly because the microtools used in ICSI were not specially designed for assisted reproduction but for other medical-biological disciplines. In view of the above caveats, the aim of the study was to co...
Source: Zygote - January 4, 2024 Category: Reproduction Medicine Authors: Francisco Vergara Javier Fern ández Concepci ón Pedrosa Mar ía Muñoz Elvira Jerez Mireia Var ón Carmen Moyano Alberto Yoldi Jordi Ponce Source Type: research

Increased Y chromosome microdeletions in cord blood of male newborns from assisted reproductive technology compared to natural conception
CONCLUSIONS: Our studies indicate that the population of male children conceived through ARTs, particularly ICSI, are at an increased risk of genetic defect in the form of partial Y chromosome microdeletions. The growing population of ART-conceived children emphasizes the importance of studying genetic repercussions of these procedures in regards to the future fertility of males conceived in vitro.PMID:38176679 | DOI:10.1016/j.jogc.2023.102342 (Source: Journal of Obstetrics and Gynaecology Canada : JOGC)
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - January 4, 2024 Category: OBGYN Authors: Richard Ng Paloma Stanar Kenny Louie Victor Chow Sai Ma Source Type: research

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)
CONCLUSIONS: We did not find that tailoring the FSH dose in any particular ORT population (low, normal, high ORT) affected live birth/ongoing pregnancy rates, but we could not rule out differences, due to sample size limitations. Low-certainty evidence suggests that it is unclear if ORT-based individualisation leads to an increase in live birth/ongoing pregnancy rates compared to a policy of giving all women 150 IU. The confidence interval is consistent with an increase of up to around six percentage points with ORT-based dosing (e.g. from 25% to 31%) or a very small decrease (< 1%). A difference of this magnitude could...
Source: Cochrane Database of Systematic Reviews - January 4, 2024 Category: General Medicine Authors: Olina Ngwenya Sarah F Lensen Andy Vail Ben Willem J Mol Frank J Broekmans Jack Wilkinson Source Type: research

Comparative study of intracytoplasmic sperm injection using the traditional holding and the oocyte-holding pipette without aspiration
Zygote. 2024 Jan 4:1-6. doi: 10.1017/S0967199423000618. Online ahead of print.ABSTRACTDespite the high level of standardization of the intracytoplasmic sperm injection (ICSI) technique, there are some aspects that deserve special attention and should still be improved. The major drawback of the technique is its invasiveness, as during cytoplasmic aspiration different structures of the oocyte may be lost or damaged. This is partly because the microtools used in ICSI were not specially designed for assisted reproduction but for other medical-biological disciplines. In view of the above caveats, the aim of the study was to co...
Source: Zygote - January 4, 2024 Category: Reproduction Medicine Authors: Francisco Vergara Javier Fern ández Concepci ón Pedrosa Mar ía Muñoz Elvira Jerez Mireia Var ón Carmen Moyano Alberto Yoldi Jordi Ponce Source Type: research

Increased Y chromosome microdeletions in cord blood of male newborns from assisted reproductive technology compared to natural conception
CONCLUSIONS: Our studies indicate that the population of male children conceived through ARTs, particularly ICSI, are at an increased risk of genetic defect in the form of partial Y chromosome microdeletions. The growing population of ART-conceived children emphasizes the importance of studying genetic repercussions of these procedures in regards to the future fertility of males conceived in vitro.PMID:38176679 | DOI:10.1016/j.jogc.2023.102342 (Source: Journal of Obstetrics and Gynaecology Canada : JOGC)
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - January 4, 2024 Category: OBGYN Authors: Richard Ng Paloma Stanar Kenny Louie Victor Chow Sai Ma Source Type: research

Comparative study of intracytoplasmic sperm injection using the traditional holding and the oocyte-holding pipette without aspiration
Zygote. 2024 Jan 4:1-6. doi: 10.1017/S0967199423000618. Online ahead of print.ABSTRACTDespite the high level of standardization of the intracytoplasmic sperm injection (ICSI) technique, there are some aspects that deserve special attention and should still be improved. The major drawback of the technique is its invasiveness, as during cytoplasmic aspiration different structures of the oocyte may be lost or damaged. This is partly because the microtools used in ICSI were not specially designed for assisted reproduction but for other medical-biological disciplines. In view of the above caveats, the aim of the study was to co...
Source: Zygote - January 4, 2024 Category: Reproduction Medicine Authors: Francisco Vergara Javier Fern ández Concepci ón Pedrosa Mar ía Muñoz Elvira Jerez Mireia Var ón Carmen Moyano Alberto Yoldi Jordi Ponce Source Type: research

Increased Y chromosome microdeletions in cord blood of male newborns from assisted reproductive technology compared to natural conception
CONCLUSIONS: Our studies indicate that the population of male children conceived through ARTs, particularly ICSI, are at an increased risk of genetic defect in the form of partial Y chromosome microdeletions. The growing population of ART-conceived children emphasizes the importance of studying genetic repercussions of these procedures in regards to the future fertility of males conceived in vitro.PMID:38176679 | DOI:10.1016/j.jogc.2023.102342 (Source: Journal of Obstetrics and Gynaecology Canada : JOGC)
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - January 4, 2024 Category: OBGYN Authors: Richard Ng Paloma Stanar Kenny Louie Victor Chow Sai Ma Source Type: research

Comparative study of intracytoplasmic sperm injection using the traditional holding and the oocyte-holding pipette without aspiration
Zygote. 2024 Jan 4:1-6. doi: 10.1017/S0967199423000618. Online ahead of print.ABSTRACTDespite the high level of standardization of the intracytoplasmic sperm injection (ICSI) technique, there are some aspects that deserve special attention and should still be improved. The major drawback of the technique is its invasiveness, as during cytoplasmic aspiration different structures of the oocyte may be lost or damaged. This is partly because the microtools used in ICSI were not specially designed for assisted reproduction but for other medical-biological disciplines. In view of the above caveats, the aim of the study was to co...
Source: Zygote - January 4, 2024 Category: Reproduction Medicine Authors: Francisco Vergara Javier Fern ández Concepci ón Pedrosa Mar ía Muñoz Elvira Jerez Mireia Var ón Carmen Moyano Alberto Yoldi Jordi Ponce Source Type: research

Increased Y chromosome microdeletions in cord blood of male newborns from assisted reproductive technology compared to natural conception
CONCLUSIONS: Our studies indicate that the population of male children conceived through ARTs, particularly ICSI, are at an increased risk of genetic defect in the form of partial Y chromosome microdeletions. The growing population of ART-conceived children emphasizes the importance of studying genetic repercussions of these procedures in regards to the future fertility of males conceived in vitro.PMID:38176679 | DOI:10.1016/j.jogc.2023.102342 (Source: Journal of Obstetrics and Gynaecology Canada : JOGC)
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - January 4, 2024 Category: OBGYN Authors: Richard Ng Paloma Stanar Kenny Louie Victor Chow Sai Ma Source Type: research