Leukocytospermia does not negatively impact outcomes in in vitro fertilization cycles with intracytoplasmic sperm injection and preimplantation genetic testing for aneuploidy: findings from 5435 cycles
ConclusionLeukocytospermia diagnosed just prior to an IVF cycle with PGT-A does not negatively impact clinical or embryologic outcomes. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 20, 2024 Category: Reproduction Medicine Source Type: research

Safety evaluation of single-sperm cryopreservation technique applied in intracytoplasmic sperm injection
Zygote. 2024 Apr 17:1-8. doi: 10.1017/S0967199424000078. Online ahead of print.ABSTRACTIntracytoplasmic sperm injection (ICSI) is a technique that directly injects a single sperm into the cytoplasm of mature oocytes. Here, we explored the safety of single-sperm cryopreservation applied in ICSI. This retrospective study enrolled 186 couples undergoing ICSI-assisted pregnancy. Subjects were allocated to the fresh sperm (group A)/single-sperm cryopreservation (group B) groups based on sperm type, with their clinical baseline/pathological data documented. We used ICSI-compliant sperm for subsequent in vitro fertilization and f...
Source: Zygote - April 17, 2024 Category: Reproduction Medicine Authors: Duanjun Zhang Wenliang Yao Mingliang Zhang Lijuan Yang Lin Li Shujuan Liu Xianglong Jiang Yingli Sun Shuonan Hu Yufang Huang Jie Xue Xiaoting Zheng Qi Xiong Shenghui Chen Haiqin Zhu Source Type: research

Safety evaluation of single-sperm cryopreservation technique applied in intracytoplasmic sperm injection
Zygote. 2024 Apr 17:1-8. doi: 10.1017/S0967199424000078. Online ahead of print.ABSTRACTIntracytoplasmic sperm injection (ICSI) is a technique that directly injects a single sperm into the cytoplasm of mature oocytes. Here, we explored the safety of single-sperm cryopreservation applied in ICSI. This retrospective study enrolled 186 couples undergoing ICSI-assisted pregnancy. Subjects were allocated to the fresh sperm (group A)/single-sperm cryopreservation (group B) groups based on sperm type, with their clinical baseline/pathological data documented. We used ICSI-compliant sperm for subsequent in vitro fertilization and f...
Source: Zygote - April 17, 2024 Category: Reproduction Medicine Authors: Duanjun Zhang Wenliang Yao Mingliang Zhang Lijuan Yang Lin Li Shujuan Liu Xianglong Jiang Yingli Sun Shuonan Hu Yufang Huang Jie Xue Xiaoting Zheng Qi Xiong Shenghui Chen Haiqin Zhu Source Type: research

Intracytoplasmic sperm injection versus in vitro fertilization in infertile women with thyroid autoimmunity
CONCLUSION: We observed that the use of ICSI in women with TAI was not associated with better assisted reproductive outcomes compared to IVF. Further prospective clinical trials are needed to confirm our findings.PMID:38623805 | DOI:10.1089/thy.2023.0676 (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - April 16, 2024 Category: Endocrinology Authors: Ning Huang Lixue Chen Zhiqiang Yan Lin Zeng Haining Wang Hongbin Chi Jie Qiao Source Type: research

Impact of dehydroepiandrosterone sulfate and free androgen index on pregnancy and neonatal outcomes in PCOS patients
CONCLUSION: In conclusion, PCOS patients with biochemical hyperandrogenism show unsatisfactory clinical PR and CLBR when undergoing assisted reproductive technology (ART). This may be attributed to the influence of both adrenal-derived DHEAS and ovarian-derived FAI on the unfavorable pregnancy outcomes.PMID:38627777 | DOI:10.1186/s12958-024-01212-y (Source: Reproductive Biology)
Source: Reproductive Biology - April 16, 2024 Category: Reproduction Medicine Authors: Wen Zhao Zeting Li Bing Cai Canquan Zhou Qingyun Mai Source Type: research

Intracytoplasmic sperm injection versus in vitro fertilization in infertile women with thyroid autoimmunity
CONCLUSION: We observed that the use of ICSI in women with TAI was not associated with better assisted reproductive outcomes compared to IVF. Further prospective clinical trials are needed to confirm our findings.PMID:38623805 | DOI:10.1089/thy.2023.0676 (Source: Thyroid : official journal of the American Thyroid Association)
Source: Thyroid : official journal of the American Thyroid Association - April 16, 2024 Category: Endocrinology Authors: Ning Huang Lixue Chen Zhiqiang Yan Lin Zeng Haining Wang Hongbin Chi Jie Qiao Source Type: research

Live birth derived from a markedly large polar body oocyte: a rare case report
In this study, it is revealed for the first time that a huge PB1 oocyte can be fertilized, resulting in the growth of a blastocyst, a subsequent pregnancy, and a live birth. This new information prompts us to reconsider the use of large PB1 oocytes. More insightful talks should be given attention to prevent the waste of embryos because not all oocytes with aberrant morphology are unavailable.PMID:38619002 | DOI:10.1017/S0967199424000054 (Source: Zygote)
Source: Zygote - April 15, 2024 Category: Reproduction Medicine Authors: Yongxiang Liu Xinliang Peng Caifeng Liu Shuting Zhang Zhiwei Weng Li Yu Shaohu Zhou Xuekun Huang Source Type: research

Live birth derived from a markedly large polar body oocyte: a rare case report
In this study, it is revealed for the first time that a huge PB1 oocyte can be fertilized, resulting in the growth of a blastocyst, a subsequent pregnancy, and a live birth. This new information prompts us to reconsider the use of large PB1 oocytes. More insightful talks should be given attention to prevent the waste of embryos because not all oocytes with aberrant morphology are unavailable.PMID:38619002 | DOI:10.1017/S0967199424000054 (Source: Zygote)
Source: Zygote - April 15, 2024 Category: Reproduction Medicine Authors: Yongxiang Liu Xinliang Peng Caifeng Liu Shuting Zhang Zhiwei Weng Li Yu Shaohu Zhou Xuekun Huang Source Type: research

Evaluating the developmental potential of 2.1PN-derived embryos and associated chromosomal analysis
ConclusionClinicians should consider using 2.1PN-derived euploid embryos for transfer after preimplantation genetic testing in the absence of available 2PN embryo cycles. 2.1PN-derived embryos could be a candidate, particularly beneficial for patients at advanced age. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 13, 2024 Category: Reproduction Medicine Source Type: research

“Walking on Eggshells”: Will PIEZO-ICSI emerge as a new standard for penetrating the PIEZona pellucida?
(Source: Fertility and Sterility)
Source: Fertility and Sterility - April 12, 2024 Category: Reproduction Medicine Authors: Stephanie Hallisey, Alison Bartolucci, Lawrence Engmann Tags: Reflections Source Type: research

“Walking on eggshells”: will PIEZO-intracytoplasmic sperm injection emerge as a new standard for penetrating the PIEZona pellucida?
In the rapidly expanding field of assisted reproductive technology, precision and efficiency are more crucial than ever. Many technologies have been developed to meet this critical need both in the laboratory and in the clinic. To introduce increased precision and standardization into the realm of intracytoplasmic sperm injection (ICSI), PIEZO-ICSI has emerged as a potential novel adjunct to conventional ICSI. (Source: Fertility and Sterility)
Source: Fertility and Sterility - April 12, 2024 Category: Reproduction Medicine Authors: Lawrence Engmann, Stephanie Hallisey, Alison Bartolucci Tags: Reflections Source Type: research

Metabolomic profiling of embryo culture media in patients with repeated implantation failure during assisted reproductive technology cycles
CONCLUSION: The metabolic profile of the culture medium of the embryos in the RIF group differed from that of the control group. These findings suggest potential factors that may affect implantation capacity in RIF patients and provide a new perspective on embryo selection.PMID:38599889 | DOI:10.5653/cerm.2023.06429 (Source: Clinical and Experimental Reproductive Medicine)
Source: Clinical and Experimental Reproductive Medicine - April 10, 2024 Category: Reproduction Medicine Authors: Sheyda Nami Azam Govahi Nabaa Najjar Samaneh Ghasemi Farshid Rezaei Fatemehsadat Amjadi Gholamreza Taheripak Source Type: research