Coronary microvascular dysfunction in childhood: An emerging pathological entity and its clinical implications
Am Heart J Plus. 2024 Apr 12;42:100392. doi: 10.1016/j.ahjo.2024.100392. eCollection 2024 Jun.ABSTRACTCoronary microvascular dysfunction (CMD) encompasses a spectrum of structural and functional alterations in coronary microvasculature resulting in impaired coronary blood flow and consequent myocardial ischemia without obstruction in epicardial coronary artery. The pathogenesis of CMD is complex involving both functional and structural alteration in the coronary microcirculation. In adults, CMD is predominantly discussed in context with anginal chest pain or existing ischemic heart disease and its risk factors. The presenc...
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Takeshi Tsuda Gina Patel Source Type: research
Exploring the effective compounds and potential mechanisms of Shengxian Decoction against coronary heart disease by UPLC-Q-TOF/MS and network pharmacology analysis
Heliyon. 2024 Apr 16;10(8):e29558. doi: 10.1016/j.heliyon.2024.e29558. eCollection 2024 Apr 30.ABSTRACTAs a well-known classical Chinese medicine prescription, Shengxian Decoction (SXD) has been applied for a century to treat cardiovascular diseases, especially coronary heart disease (CHD), but the potentially effective compounds and underlying mechanisms remain unclear. With ultra-performance liquid chromatography-quadrupole-time of flight-mass spectrometry (UPLC-Q-TOF/MS) and network pharmacology analysis, the potential effective compounds of SXD and their pharmacological mechanisms against CHD were identified and reveal...
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Hao-Ming Zhou Shi-Jun Yue Wen-Xiao Wang Qiao Zhang Ding-Qiao Xu Jia-Jia Li Yu-Ping Tang Xin-Yu Yang Source Type: research
Molecular mimic between cardiovascular diseases and microorganism antigens
CONCLUSION: Human actin and HSPs share a high degree of conservation with epitopes from various microorganisms, such as bacteria, fungi and protozoa, suggesting molecular mimicry and cross-reactivity as a mechanism for the development of atherosclerosis, heart disease rheumatic disease, myocarditis and Chagas heart disease. In vitro and in vivo work is needed to demonstrate the results obtained in the In Silico analysis.PMID:38683079 | DOI:10.29262/ram.v71i1.1379 (Source: Atherosclerosis)
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Andr és Sánchez-Caraballo Valentina Garc ía-Solano Sonia Karina Gonz ález-Rangel Valeria Grattz-Lamadrid Marlon Munera-Gomez Source Type: research
Risk of Adverse Cardiovascular Outcomes in Postmenopausal Women with Inflammatory Bowel Disease
ConclusionsAmong postmenopausal women with IBD, risk of ischemic stroke may be higher than in non-IBD women. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 29, 2024 Category: Gastroenterology Source Type: research
Use of Virtual Reality and 3D Models in Contemporary Practice of Cardiology
AbstractPurpose of ReviewTo provide an overview of the impact of virtual and augmented reality in contemporary cardiovascular medical practice.Recent FindingsThe utilization of virtual and augmented reality has emerged as an innovative technique in various cardiovascular subspecialties, including interventional adult, pediatric, and adult congenital as well as structural heart disease and heart failure. In particular, electrophysiology has proven valuable for both diagnostic and therapeutic procedures. The incorporation of 3D reconstruction modeling has significantly enhanced our understanding of patient anatomy and morpho...
Source: Current Cardiology Reports - April 29, 2024 Category: Cardiology Source Type: research
Enhancing Congenital Cardiac Postprocedural Care: A QR Code-Enabled Medical Bracelet Pilot Study
AbstractThe study aimed to evaluate the feasibility of using QR code-enabled medical bracelets for congenital heart disease (CHD) patients after hospital discharge to ensure quick communication of vital information to other medical personnel in emergency situations. A prospective study was conducted where QR code-enabled medical bracelets were given to families of postoperative pediatric cardiac patients. The QR code linked to a secure medical information sheet detailing the patient ’s cardiac history. Post-study surveys were completed by providers and families to assess their experiences with the bracelet. Of the 20 par...
Source: Mammalian Genome - April 28, 2024 Category: Genetics & Stem Cells Source Type: research
Drug-coated balloon in the treatment of coronary artery de-novo large lesions angiography
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):196-201. doi: 10.14715/cmb/2024.70.4.31.ABSTRACTThe superiority of drug-coated balloon (DCB) in treating small vessels, branching lesions, and high-risk bleeding lesions in coronary heart disease patients has been confirmed. However, its safety and efficacy in large vessels are still unclear. We aimed to investigate whether the efficacy of DCB in large vessels is not inferior to that of drug-eluting stent (DES). From November 2019 to April 2022, a total of 88 patients in our hospital who underwent coronary angiography for the first time and decided to receive DCB or DES tre...
Source: Cellular and Molecular Biology - April 28, 2024 Category: Molecular Biology Authors: Xingyou Cai Xin Hong Yuli Wang Yafei Li Guidong Xu Source Type: research
Drug-coated balloon in the treatment of coronary artery de-novo large lesions angiography
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):196-201. doi: 10.14715/cmb/2024.70.4.31.ABSTRACTThe superiority of drug-coated balloon (DCB) in treating small vessels, branching lesions, and high-risk bleeding lesions in coronary heart disease patients has been confirmed. However, its safety and efficacy in large vessels are still unclear. We aimed to investigate whether the efficacy of DCB in large vessels is not inferior to that of drug-eluting stent (DES). From November 2019 to April 2022, a total of 88 patients in our hospital who underwent coronary angiography for the first time and decided to receive DCB or DES tre...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Xingyou Cai Xin Hong Yuli Wang Yafei Li Guidong Xu Source Type: research
Drug-coated balloon in the treatment of coronary artery de-novo large lesions angiography
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):196-201. doi: 10.14715/cmb/2024.70.4.31.ABSTRACTThe superiority of drug-coated balloon (DCB) in treating small vessels, branching lesions, and high-risk bleeding lesions in coronary heart disease patients has been confirmed. However, its safety and efficacy in large vessels are still unclear. We aimed to investigate whether the efficacy of DCB in large vessels is not inferior to that of drug-eluting stent (DES). From November 2019 to April 2022, a total of 88 patients in our hospital who underwent coronary angiography for the first time and decided to receive DCB or DES tre...
Source: Cellular and Molecular Biology - April 28, 2024 Category: Molecular Biology Authors: Xingyou Cai Xin Hong Yuli Wang Yafei Li Guidong Xu Source Type: research
Traditional Cardiovascular Risk Factors and Coronary Microvascular Disease in Women and Men- A Single Center Study
Conclusion For the entire population, no association was found between coronary microvascular dysfunction and traditional risk factors for coronary atherosclerosis. In women only, older age and previous ischemic heart disease were associated with coronary microvascular dysfunction. Larger studies are needed to elucidate risk factors for CMD.PMID:38679011 | DOI:10.1159/000539102 (Source: Atherosclerosis)
Source: Atherosclerosis - April 28, 2024 Category: Cardiology Authors: Lior Zornitzki Aviel Shetrit Ophir Freund Shir Frydman Ariel Banai Reut Amar Shamir Jeremy Ben-Shoshan Yaron Arbel Shmuel Banai Maayan Konigstein Source Type: research
Drug-coated balloon in the treatment of coronary artery de-novo large lesions angiography
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):196-201. doi: 10.14715/cmb/2024.70.4.31.ABSTRACTThe superiority of drug-coated balloon (DCB) in treating small vessels, branching lesions, and high-risk bleeding lesions in coronary heart disease patients has been confirmed. However, its safety and efficacy in large vessels are still unclear. We aimed to investigate whether the efficacy of DCB in large vessels is not inferior to that of drug-eluting stent (DES). From November 2019 to April 2022, a total of 88 patients in our hospital who underwent coronary angiography for the first time and decided to receive DCB or DES tre...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Xingyou Cai Xin Hong Yuli Wang Yafei Li Guidong Xu Source Type: research
Histologically Validated Myocardial Fibrosis in Relation to Left Ventricular Geometry and Its Function in Aortic Stenosis
Conclusions: Histological MF in AS was correlated with LVM and LVEDD in all study periods. No correlations between MF and LV parameters were found in aortic stenosis in the ischemic heart disease group across all study periods.PMID:38674313 | PMC:PMC11052378 | DOI:10.3390/medicina60040667 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Serik Aitaliyev Egle Rumbinait ė Martynas Jurenas Indr ė Čeponienė Vytenis Keturakis Rokas Nekro šius Yerlan Orazymbetov Rimantas Benetis Dalia Pangonyt ė Source Type: research
